Inter Partes Review of U.S. Patent No. 9,517,219 Declaration of Elaine S. Gilmore, M.D., Ph.D. (Exhibit 1018) claimed invention; the analysis may include recourse to logic, judgment, and common sense available to a person of ordinary skill that does not necessarily require an explicit teaching, suggestion, or motivation in any reference.

without a certification in dermatology (i.e., a primary care physician, or a pediatrician) may qualify as a clinical POSA, assuming that they have more than two years of knowledge and experience treating skin conditions.

Inter Partes Review of U.S. Patent No. 9,517,219 Declaration of Elaine S. Gilmore, M.D., Ph.D. (Exhibit 1018) mg/week.” (Id., 1:8-11; see also AMN1007, [0003] [explaining that dapsone can be used to treat acne, rosacea, and other “skin diseases characterized by the abnormal infiltration of neutrophils.”].)

(AMN1004, 1) A POSA in 2012 would understand that Garrett teaches methods of treating both rosacea and acne consisting of inflammatory and non-inflammatory lesions by applying topical compositions containing dapsone to a patient’s affected areas.

First, the reduction in number of daily applications is not unexpected, as dermatologists expected at the time of invention that the potency, or strength, of a given drug is related to both its duration of action and its side effects.

www.Healthtap.com (August 2014 – current) Position: Founding doctor and dermatologist/allergist practicing telemedicine for dermatology and general medicine patients.

Membership and Honorary/Professional Societies: Golden Key International Academic Honor Society, American Medical Student Association (AMSA), American Medical Association (AMA), American Academy of Pediatrics (AAP), Fellow, ACAAI, Fellow AAAAI, Fellow FAAD Honors / Awards: Academic All American; Verizon Academic All-Midwest; Member of Golden Key International Academic Honor Society; Snake Award Winner given annually to the highest achieving medical student group at UMKC; Student Representative at Chancellor's Symposium On Future Planning For Statewide University of Missouri System; Elected fellow representative for Children’s Mercy Hospital residency council.

Clinical utility of pseudopod development on skin prick testing (under review) Textbook chapter: The Autoimmune diseases.

My responsibilities included interviewing and evaluating applicants to the School of Medicine and making recommendations for acceptance for incoming classes 04/ 2001 - 04/2006 Kansas City Parks and Recreation Department, Missouri Volunteer soccer coach for underprivileged youth This volunteer based organization was designed to promote health and wellness as well as a safe environment for underprivileged youth of Kansas City.

Background, Hobbies & Interests: I grew up in Long Island New York and attended the 6 year combined BA/MD program at the University of Missouri-Kansas City.

Glen Marston, sales manager for Evonik Degussa’s AEROSIL® line, has the following comments to this change of organisation: “In our experience, working with the pharmaceutical in- dustry requires, among other things, long term commitment, technical com- petence and a thorough under- standing of the development process in the industry.

Traditional emulsions used for topical applications can be a headache when you build your surfactant system using a lipophilic plus a hydrophilic sur- factant, calculate the HLB of the sys- tem and then add a thickener to ob- tain consistency.

Along with this shift in role, several other initiatives were introduced to the customers such as newsletters, semi- nars and travel arrangements in con- nection with the now biannual Food Ingredients Europe exhibition - all ini- tiatives which are still in place.

Ayurveda offers specific recommenda- tions to each individual on lifestyle, diet, exercise and yoga, herbal therapy, and even spiritual practices to restore and maintain balance in body and mind.

Used in functional foods such as beverages, dairy prod- ucts, or in dietetics products as meal substitute or in dietary supplements, Lactium® is a valuable solution to over- weight problems due to stress.

Commercially available with a 5% concentration of dapsone, this gel material also includes Car homer 980 as a thickener, methylparaben as a preservative, diethyleneglycol monoethyl ether (DGME) as a cosolvent, and sodium hydroxide for pH adjustment.

For example, as is well known in the art, larger particles tend to dissolve or disperse more slowly due to the lower surface area/volume ratio in comparison with smaller but similarly shaped particu lates.

indamyl, carbenicillin, mezlocillin, piperacillin, ticarcillin, cloxacillin, dicloxacillin, floxacillin, methicillin, nafcillin, oxacillin, colistmethate, polyrnixin b, trimethoprim, cotrimoxazole, mafenide, sulfadiazine, sodium sulfacetamide, sulfacytine, sulfadiazine, sul famethoxazole, sulfapyridine, sulfasalazine, sulfisoxazole, chloramphenicol, clindamycin, spectinomycin, azithromy cin, clarithromycin, erythrmoycin, erythromycin estolate, spiramycin, chlortetracycline, demeclocycline, doxycycline, minocycline, oxytetracycline, amikacin, kanamycin, neomy cin, streptomycin, tobramycin, nitrofurantoin, griseofulvin, potassium iodide, fluconazole, itraconazole, ketoconazole, miconazole, clotrimazole, amphotericin b, nystatin, niclosa mide, nifurtimox, piperazine, praziquantel, pyrantel pamo ate, ascariasis, pinworm, thiabendazole, amodiaquine, chlo roquine, hydroxychloroquine, mefloquine, primaquine, pyrimethamine, quinidine gluconate, fansidar, diloxanide furoate, melarsoprol, nifurtimox, paromomycin, pentami dine, sodium stibogluconate, suramin, metronidazole, foscar net, 3-deoxythmidin-2-ene, dideoxycytosine, dideoxyi nosine, lamivudine, azidothymidine, indinavir, ritonavir, Mylan (IPR2019-01095) MYLAN1008, p. 005

These substances, called the coal-tar crudes, form the starting point for the synthesis of numerous prod ucts-notably dyes, drugs, explosives, flavorings, perfumes, preservatives, synthetic resins, and paints and stains.

fasciitis, relapsing polychondritis, and vasculitis), sarcoidosis, Sweet's disease, lichen planus, hirsutism, toxic epidermal necrolysis, derma titis herpetiformis, eczema, atopic dermatitis, seborrhoeic dermatitis (dandruff, cradle cap), diaper rash, urushiol-in duced contact dermatitis, erythroderma, lichen simplex chronicus, prurigo nodularis, itch, pruritus ani, nummular dermatitis, dyshidrosis, pityriasis alba, parapsoriasis (pityri asis lichenoides et varioliformis acuta, pityriasis lichenoides chronica ), pityriasis rosea, pityriasis rubra pilaris, urticaria (dermatographic urticaria, cholinergic urticaria), erythema (erythema nodosum, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema annulare centrifugum, erythema marginatum), sunburn, actinic kera tosis, polymorphous light eruption, radiodermatitis, erythema ab igne, nail disease, onychogryposis, Beau's lines, yellow nail syndrome, follicular disorders, alopecia areata (alopecia universalis), androgenic alopecia, telogen efflu vium, lichen planopilaris, trichorrhexis nodosa, hypertricho sis (hirsutism), epidermoid cysts, sebaceous cysts, pseudofol liculitis barbae, hidradenitis suppurativa, miliaria, anhidrosis, body odor, chromhidrosis, vitiligo, melasma, freckles, cafeau lait spots, lentigo/liver spots, seborrheic keratosis, acanthosis nigricans, callus, pyoderma gangrenosum, bedsores, keloids, granuloma annulare, necrobiosis lipoidica, granuloma faciale, morphea, calcinosis cutis, sclerodactyly, ainhum and livedoid vasculitis.