UNITED STATES PATENT AND TRADEMARK OFFICE
`
`BEFORE THE PATENT TRIAL AND APPEAL BOARD
`
`
`ARKEMA INC. AND ARKEMA FRANCE
`Petitioner,
`v.
`
`HONEYWELL INTERNATIONAL INC.,
`Patent Owner.
`
`
`PGR2016-00011
`Patent No. 9,157,017
`
`
`PATENT OWNER’S EIGHTH AMENDED APPENDIX OF EXHIBITS
`
`
`
`
`
`
`
`
`

`

`PGR2016-00011
`
`
`
`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Description
`Exhibit No.
`Declaration of Donald Bivens
`Exhibit 2001
`Curriculum Vitae of Donald Bivens
`Exhibit 2002
`U.S. Patent No. 5,182,040 to Bartlett et al.
`Exhibit 2003
`U.S. Patent No. 5,516,446 to Bivens and Yokozeki
`Exhibit 2004
`U.S. Patent No. 5,648,017 to Bartlett et al.
`Exhibit 2005
`U.S. Patent No. 5,725,791 to Bivens et al.
`Exhibit 2006
`U.S. Patent No. 5,968,406 to Bartlett et al.
`Exhibit 2007
`U.S. Patent No. 7,914,968 to Minor et al.
`Exhibit 2008
`U.S. Patent No. 7,959,825 to Minor et al.
`Exhibit 2009
`Exhibit 2010 Wilson, C. L. et al., Abstract: Man's Impact on the Global
`Environment: Assessment and Recommendation for Action.
`Report of the Study of Critical Environmental Problems (SCEP),
`(1970),
`available
`at:
`MIT Press, Cambridge, Mass.
`http://hdl.handle.net/1969.3/26655
`A. Hammond, Book Review of W. Matthews et al., Study of
`Man's Impact on Climate (SMIC) Report, Inadvertent Climate
`Modification, MIT Press, Cambridge, Mass. (1971), SCIENCE
`Vol. 176, available at: http://science.sciencemag.org/content/
`176/4030/38.2
`V. Ramanathan, Greenhouse Effect Due to Chlorofluorocarbons:
`Climate Implications, SCIENCE: American Association for the
`Advancement of Science, Vol. 190 (1975), available at:
`http://science.sciencemag.org
`J. Calm and D. Didion., Trade-Offs in Refrigerant Selections:
`Past, Present, and Future, ASHRAE/NIST Refrigerants
`Conference (October 1997)
`B. Newell and T. Newell, In Situ, Real Time Oil Concentration in
`a Mobile Air Conditioning System, NI Tech Bulletin 001, Newell
`Instruments, Inc.
`ACURA Service Bulletin, R-134a Refrigerant A/C System, Sept.
`29, 1992 for model NSX Legend, year 1993
`2013 ASHRAE Handbook Fundamentals, SI Ed., Chapter 29:
`Refrigerants, Table 3
`Dometic, Material Safety Data Sheet, March 25, 2015
`ICI Americas, Inc., PAG-46, Material Safety Data Sheet (Feb. 9,
`1999)
`
`Exhibit 2015
`
`Exhibit 2016
`
`Exhibit 2017
`Exhibit 2018
`
`
`
`1
`
`Exhibit 2011
`
`Exhibit 2012
`
`Exhibit 2013
`
`Exhibit 2014
`
`

`

`PGR2016-00011
`
`
`
`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2019
`
`Exhibit 2020
`Exhibit 2021
`
`Presentation, Exposure Limits: TLVs, BEIs, PELs, RELs, WEELs,
`OELs,
`available
`online
`at:
`ERPGs
`and
`http://isites.harvard.edu/fs/docs/icb.topic156420.files/Exposure_
`Limits
`U.S. Patent No. 6,516,837 to Thomas et al.
`Pate, Michael, et al., Miscibility Of Lubricants With Refrigerants,
`Final Report, Iowa State University of Science and Technology
`Department of Mechanical Engineering (July 1993)
`Crown, S.W., et al., A Comparison Study of the Thermal
`Performance of R12 and R134a, International Refrigeration and
`Air Conditioning Conference (1992)
`Uemura, S., et al., Characteristics of HFC Refrigerants,
`International Refrigeration and Air Conditioning Conference
`(1992)
`Brown, J. Steven, et al., The fluorinated olefin R-1234ze(Z) as a
`high-temperature heat pumping refrigerant, International Journal
`of Refrigeration 32, 1412-1422 (2009)
`Case Law of the Board of Appeal of the European Patent Office
`(Seventh Edition, Sept. 2013)
`Bristol Compressors, Medium and Low Temperature Retrofit
`from R502 to R404A/R507, Application Bulletin 125 (Release
`date Oct. 20, 1995)
`Exhibit 2027 Wilson, C. L. et al., Man's Impact on the Global Environment:
`Assessment and Recommendation for Action. Report of the Study
`of Critical Environmental Problems (SCEP), MIT Press,
`Cambridge, Mass. (1970)
`Exhibit 2028 Matthews, W., et al., Study of Man's Impact on Climate (SMIC)
`Report,
`Inadvertent Climate Modification, MIT Press,
`Cambridge, Mass. (1971)
`Case Law of the Board of Appeal of the European Patent Office
`(Seventh Edition, Sept. 2013)
`ASHRAE Standard, Designation and Safety Classification of
`Refrigerants, American Society of Heating, Refrigerating and
`Air-Conditioning, Inc.(Nov. 18, 2009)
`United States Environmental Protection Agency’s Office of
`Pesticide Programs, Summary of the IBT Review Program (July
`1983)
`Exhibit 2032 Manual for Investigation of HPV Chemicals, Chapter 3: Data
`Evaluation
`
`Exhibit 2022
`
`Exhibit 2023
`
`Exhibit 2024
`
`Exhibit 2025
`
`Exhibit 2026
`
`Exhibit 2029
`
`Exhibit 2030
`
`Exhibit 2031
`
`
`
`2
`
`

`

`PGR2016-00011
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`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2033
`
`Exhibit 2034
`
`Exhibit 2035
`Exhibit 2036
`Exhibit 2037
`
`Exhibit 2038
`Exhibit 2039
`
`Exhibit 2040
`Exhibit 2041
`Exhibit 2042
`Exhibit 2043
`
`Exhibit 2044
`
`Exhibit 2045
`
`Exhibit 2046
`
`TSCA Filing, Refrigerant 1243zf; TNO Quality of Life Report: A
`sub-acute (28-day)
`inhalation
`toxicity study with 3,3,3,-
`trifluoroprop-1-ene (HFO 1234zf) in rats (Dec. 3, 2010)
`Clayton Jr., J. Wesley, Chapter 9: The Mammalian Toxicology of
`Organic Compounds Containing Fluorine (1996)
`U.S. Patent No. 5,569,797 to Fu et al.
`U.S. Patent No. 5,001,287 to Fernandez et al.
`ECETOC Technical Report No. 103: Toxicity of Possible
`Impurities and By-products in Fluorocarbon Products (December
`2008)
`U.S. Patent Application No. 13/939,233
`Transcript of Mar. 29, 2016 telephone proceedings before the
`Board
`Transcript of Nov. 28, 2016 teleconference with the Board
`Transcript of Nov. 29, 2016 teleconference with the Board
`US Patent Publication No. 2012/0292556 A1
`Brown, J. Steven, HFOs: New, Low Global Warming Potential
`Refrigerants, ASHRAE Journal (August 2009)
`Brown, J. Steven, Low Global Warming Potential Refrigerant
`Options for Unitary Equipment, ASHRAE Winter Conference
`(2011)
`Beattie, Roger J., et al., Investigation of Low GWP Refrigerant
`Interaction with Various Lubricant Candidates, Purdue
`at
`available
`University
`(2012),
`http://docs.lib.purdue.edu/iracc/1223
`Domanski, Piotr A., et al., NIST, Transition to Low-GWP
`Refrigerants: Options and Tradeoffs, Florida International
`University (April 1, 2016)
`Exhibit 2047 McLinden, Mark O., NIST, Thermodynamic Analysis for Low-
`GWP Refrigerants, ASHRAE Winter Conference (Jan. 19, 2014)
`Deposition Transcript of Dr. William J. Brock (Dec. 1, 2016)
`Deposition Transcript of Dr. J. Steven Brown (Dec. 8, 2016)
`Brown, J. Steven et al., Comparative analysis of an automotive
`air conditioning systems operating with CO2 and R134a,
`International Journal of Refrigeration (2002)
`Brown, Steven J., Potential R-114 Replacement Refrigerants,
`ASHRAE Transactions, Vol. 114 (2008)
`Brown, J. Steven, et al., Thermodynamic properties of eight
`fluorinated olefins, International Journal of Refrigeration, (2010)
`
`Exhibit 2048
`Exhibit 2049
`Exhibit 2050
`
`Exhibit 2051
`
`Exhibit 2052
`
`
`
`3
`
`

`

`PGR2016-00011
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`
`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2053
`
`Exhibit 2054
`
`Exhibit 2055
`
`Exhibit 2056
`
`Clodic, Denis, Automobile Air-conditioning: Environmental
`Stakes and Future Technical Options, Journal of Cold and Air-
`conditioning (May 2008)
`Clodic, Denis, et al., Characteristics and Performances of New
`Refrigerants, ADEME Technical Day (Sept. 23, 1999)
`Ember, Lois R., et al., Tending the Global Commons, C&EN
`(Nov. 24, 1986)
`EPA Approves New Coolant for Car AC Systems/Better climate
`protection without harming the ozone layer, available at
`https://yosemite.epa.gov (Feb. 28, 2011)
`Fisher, Donald A., et al., Model calculations of the relative effects
`of CFCs and their replacements on global warming, Nature, Vol.
`433 (April 5, 1990)
`al., Flammability assessment of
`et
`Takizawa, Kenji,
`CH2=CFCF3:
`Comparison
`with
`fluoroalkenes
`and
`fluoroalkanes, Journal of Hazardous Materials (2009)
`Kondo, Shigeo, et al., Flammability limits of olefinic and
`saturated fluoro-compounds, Journal of Hazardous Materials
`(2009)
`(Editor), Fluorine Chemistry: A
`Howe-Grant, Mary
`Comprehensive Treatment (1995)
`French Patent, No. 0 495 543 A1 (1992)
`Exhibit 2061
`Exhibit 2061A French Patent, No. 0 495 543 A1 (1992) with certified translation
`Exhibit 2062
`Gad,
`Shayne C.,
`et
`al.,
`Inhalation
`Toxicity
`of
`Hexafluoroisobutylene, Toxicology and Applied Pharmacology
`(March 31, 1986)
`GM First to Market Greenhouse Gas-Friendly Air Conditioning
`Refrigerant in U.S., available at: http://www.gm.com (July 23,
`2010)
`Refrigerant Selection and System Design – the role of HFCs,
`Institute of Refrigeration, Guidance Note 18 (April 18, 2009)
`US Patent Publication No. 2011/0312101 A1
`Exhibit 2065
`Exhibit 2066 William L. Kopko, Beyond CFCs - Extending the Search for New
`Refrigerant, Proceedings of ASHRAE’s 1989 CFC Technology
`Conference (1989)
`Exhibit 2066A William L. Kopko, Beyond CFCs - Extending the Search for New
`Refrigerant, Proceedings of ASHRAE’s 1989 CFC Technology
`Conference (1989)
`
`Exhibit 2057
`
`Exhibit 2058
`
`Exhibit 2059
`
`Exhibit 2060
`
`Exhibit 2063
`
`Exhibit 2064
`
`
`
`4
`
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`PGR2016-00011
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`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2068
`Exhibit 2069
`
`Exhibit 2070
`
`Exhibit 2071
`
`Exhibit 2072
`
`Exhibit 2072A
`
`Exhibit 2067 McLinden, Mark O., et al., Quest for Alternatives: A molecular
`approach demonstrates tradeoffs and limitations are inevitable in
`seeking refrigerants, ASHRAE Journal (December 1987)
`Exhibit 2067A McLinden, Mark O., et al., Quest for Alternatives: A molecular
`approach demonstrates tradeoffs and limitations are inevitable in
`seeking refrigerants, ASHRAE Journal (December 1987)
`Reserved
`Amendment and Response for Stable Formulated Systems with
`Chloro-3,3,3,-Trifluoropropene, U.S. Patent and Trademark
`Office, Serial No. 12/667,121 (Dec. 29, 2009)
`Amendment and Response for Heat Transfer of Oxygenated
`Lubricant with Hydrofluoroolefin and Hydrochlorofluoroolefin
`Refrigerants, U.S. Patent and Trademark Office, Serial No.
`14/715,753 (May 19, 2015)
`Lindley, Andrew A., et al., Consideration of Hydrofluoroolefins
`(HFOs) as potential candidate medical propellants, Mexichem
`Fluor (April 2010)
`Jones, J. (Inventor), Nearly Azeotropic Mixtures to Replace
`Refrigerant 12, NASA Tech Brief from JPL New Technology
`Report, Vol. 16 (August 1992)
`Jones, J. (Inventor), Nearly Azeotropic Mixtures to Replace
`Refrigerant 12, NASA Tech Brief from JPL New Technology
`Report, Vol. 16 (August 1992)
`Reisch, Marc S., Perkins Medal Goes To Ian Shankland,
`Chemical & Engineering News (July 23, 2008)
`Brown, J. Steven, Preliminary Selection of R-114 Replacement
`Refrigerants Using Fundamental Thermodynamic Parameters
`(RP-1308), HVAC&R Research, Vol. 13 (2007)
`European Patent Application No. 0 430 171 A1 (Nov. 27, 1990)
`U.S. Patent No. 5,136,854 (Aug, 11, 1992)
`U.S. Patent No. 5,744,052 (April 28, 1998)
`U.S. Patent No. 6,258,292 (July 10, 2001)
`Carvalho, Suely,
`et.
`al., Alternatives
`to High-GWP
`Hydrofluorocarbons, Institute for Governance & Sustainable
`Development
`Exhibit 2080 Wang, Linda, Rajiv Singh Wins Schoellkopf Award, American
`Chemical Society, Chemical & Engineering News, Vol. 87, Issue
`12 (March 23, 2009)
`
`Exhibit 2073
`
`Exhibit 2074
`
`Exhibit 2075
`Exhibit 2076
`Exhibit 2077
`Exhibit 2078
`Exhibit 2079
`
`
`
`5
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`PGR2016-00011
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`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2082
`
`Exhibit 2083
`
`Exhibit 2081 UNEP, 2002 Report of The Refrigeration, Air Conditioning and
`Heat Pumps, Technical Options Committee, Montreal Protocol
`On Substances that Deplete the Ozone Layer (2002)
`Fischer, S.K., et al., Energy and Global Warming Impacts of CFC
`Alternative Technologies, AFEAS & DOE (December 1991)
`Specifications for Fluorocarbon Refrigerants, Air-Conditioning
`and Refrigeration Institute (2006)
`Exhibit 2084 Henne, Albert L., et. al., Fluorinated Derivatives of Propane and
`Propylene, Department of Chemistry at the Ohio State University
`(1945)
`Exhibit 2085 Haszeldine, R. N., Reactions of Fluorocarbon Radicals, Part V,
`Alternative Syntheses for Trifluoromethylacetylene (3:3 3-
`Trifluoropropyne), and the Influence of Polyfluoro-groups on
`Adjacent Hydrogen and Halogen Atoms, University Chemical
`Laboratory, Cambridge (April 10, 1951)
`P. L. Houston, Chemical Kinetics and Reaction Dynamics,
`Chapter 2: The Rates of Chemical Reactions (April17, 2000)
`(available
`at
`http://www.cosbkup.gatech.edu/group/chem780/CHAPT2.pdf)
`Exhibit 2086A P. L. Houston, Chemical Kinetics and Reaction Dynamics,
`Chapter 2: The Rates of Chemical Reactions (April17, 2000)
`(available
`at
`http://www.cosbkup.gatech.edu/group/chem780/CHAPT2.pdf)
`Exhibit 2087 Keck Graduate
`Institute online
`textbook
`(available at
`http://sbw.kgi.edu/sbwwiki/_media/sysbio/labmembers/hsauro/s
`ystemsandsynthetic_biology3.pdf)
`
`Exhibit 2087A Herbert M. Sauro, Spring 2008: Systems and Synthetic Biology,
`Week
`1,
`PowerPoint
`3,
`http://sbw.kgi.edu/sbwWiki/_media/sysbio/labmembers/hsauro/s
`ystemsandsynthetic_biology3.pdf.
`Exhibit 2088 U.S. Patent Publication No. 2011/0012052 A1 (Jan. 20, 2011)
`Exhibit 2089 Amendment and Response with Request for Continued
`Prosecution by Arkema, Inc. re U.S. Patent Publication No.
`2011/0012052, Serial No. 12/667,140 (Dec. 29, 2009)
`Exhibit 2090 U.S. Patent No. 5,152,845 (Oct. 6, 1992)
`Exhibit 2091
`Action on Ozone, Ozone Secretariat, United Nations Environment
`Programme (2000)
`
`Exhibit 2086
`
`
`
`6
`
`

`

`PGR2016-00011
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`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2092
`
`Exhibit 2096
`
`Exhibit 2097
`
`Exhibit 2098
`
`Studies in Geophysics: Energy and Climate, National Academy
`of
`Sciences,
`available
`at
`https://www.nap.edu/catalog/12024/energy-and-climate-studies-
`in-geophysics (1977)
`Exhibit 2093 Didion, David A., et al., Role of refrigerant mixtures as
`alternatives to CFCs, Rev. Int. Froid, Vol. 13 (May 13, 1990)
`Exhibit 2094 Declaration of Margaret H. Whittaker
`Exhibit 2095 Directive 2006/40/EC of the European Parliament and of the
`Council Relating to emissions from air-conditioning systems in
`motor vehicles and amending Council, Directive 70/156/EEC,
`Official Journal of the European Union (May 17, 2006)
`Klimisch, H.-J., et al., A Systematic Approach for Evaluating the
`Quality of Experimental Toxicological and Ecotoxicological
`Data, Regulatory Toxicology and Pharmacology (1997).
`Bhatti, M.S., A Critical Look at R-744 and R-134a, Mobile Air
`Conditioning Systems, Reprinted from Automotive Climate
`Control Design Elements (SP-1239) (1997)
`Arkema Beefs Up Chemicals; Eyes Acquisition of Acrylics Assets,
`Chemical Week Business and Finance News (2008)
`Exhibit 2098A Arkema Beefs Up Chemicals; Eyes Acquisition of Acrylics Assets,
`Chemical Week Business and Finance News (2008)
`Exhibit 2099 VDA Annual Report (2011)
`Exhibit 2100
`Recognizing our Heroes of Chemistry, American Chemical
`Society, available at https://www.acs.org/content/acs/en/funding-
`and-awards/awards/industry/heroes.html (2016)
`Exhibit 2101 Declaration of Richard Winick, U.S. Patent and Trademark
`Office, In re Reexam Control Nos. 95/002,189 and 95/002,204,
`U.S. Patent No. 7,534,366 (Filed Sept. 12, 2012)
`Exhibit 2102 Declaration of Richard Winick, U.S. Patent and Trademark
`Office, In re Reexam Control No. 95/002,030, U.S. Patent No.
`8,065,882 (Filed Aug. 20, 2012)
`Exhibit 2103 Declaration of Raymond Thomas, U.S. Patent and Trademark
`Office, In re Reexam Control Nos. 95/002,189 & 95/002,204,
`U.S. Patent No. 7,534,366 (Filed Sept. 12, 2012)
`Schulze, Christian, et. al., Transient evaluation of a city bus air
`conditioning system with R-445A as drop-in -- From the
`molecules to the system, International Journal of Thermal
`Sciences (2015)
`Li, Xinzhong, et. al., Optimization of Heat Exchanger for
`
`Exhibit 2104
`
`Exhibit 2105
`
`
`
`7
`
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`

`PGR2016-00011
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`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2106
`
`Exhibit 2107
`Exhibit 2108
`
`High Glide Blend: Condenser model and its application in
`optimization for AC6 , SAE International (Oct. 31, 2012)
`Enrique Peral-Antúnez (Chairperson), MAC Refrigerant Blend
`Cooperative Research Program Update, SAE International (Oct.
`31, 2012)
`Factsheet 19, Hydrofluoroolefins, EFCTC (June 2011)
`Commercial CO2 Refrigeration Systems : Guide for Subcritical
`and Transcritical CO2 Applications, Emerson Climate Study
`(2015)
`Exhibit 2109 Chemours Congratulates the Parties to the Montreal Protocol for
`HFC Amendment Agreement, Chemours Article (Oct. 17, 2016)
`Exhibit 2110 Honeywell Scientists Recognized As “Heroes of Chemistry” For
`Development Of Low-Global-Warming Refrigerant , Honeywell
`Press Release (June 17, 2016)
`Exhibit 2111 AHRI Past Programs -- 21CR Program, MCLR Program (2011)
`Exhibit 2112 Halocarbons: Environmental Effects of Chlorofluoromethane
`Release, Committee on Impacts of Stratospheric Change,
`Assembly of Mathematical and Physical Sciences National
`Research Council, National Academy of Sciences (1976)
`Exhibit 2113 Darryl D. DesMarteau Curriculum Vitae
`Exhibit 2114
`Peroxide formation in glycol ethers, Dow Answer Center, The
`Dow
`Chemical
`Company,
`available
`at
`http://dowac.custhelp.com/app/answers/detail/a_id/11446/~/pero
`xide-formation-in-glycol-ethers (Nov. 15, 2011)
`Exhibit 2115 U.S. Patent No. 5,355,695 to Kawaguchi et al. (Oct. 18, 1994)
`Exhibit 2116 Hudlický, Miloš, Organic Fluorine Chemistry, Dept. of
`Chemistry, Virginia Polytechnic Institute and State University
`(1971)
`Exhibit 2116A Hudlický, Miloš, Organic Fluorine Chemistry, Dept. of
`Chemistry, Virginia Polytechnic Institute and State University
`(1971)
`Exhibit 2117 Amendments and Remarks to the Claims in Response to Office
`Action Mailed May 29, 2014, in re Patent Application No.
`14/225,588 (Aug. 29, 2014)
`Sealed Glass Tube Method to Test the Chemical Stability of
`for Use within Refrigerant Systems, ASHRAE
`Materials
`Standard (2007)
`Exhibit 2119 U.S. Patent No. 5,419,144 to Kawaguchi et al. (May 30, 1995)
`
`Exhibit 2118
`
`
`
`8
`
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`PGR2016-00011
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`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2130
`
`Exhibit 2120 U.S. Patent No. 5,746,933 to Ishida et al. (May 5, 1998)
`Exhibit 2121 U.S. Patent No. 6,299,792 B1 to Feiring et al. (Oct. 9, 2001)
`Exhibit 2122
`The Exponetial Growth of HFO-1234yf in Automotive Air
`Conditioning, Opteon YF, The Chemours Company (2016)
`Exhibit 2123 U.S. Patent Application No. 2013/0296617 A1 (Nov. 7, 2013)
`Exhibit 2124 Atiyeh, Clifford, Global Cooling: Mercedes to Debut Air
`Conditioning with CO2 Refrigerant, Hearst Communications,
`Inc. (Oct. 26, 2015)
`Exhibit 2125 Margaret H. Whittaker Curriculum Vitae (2016)
`Exhibit 2126 Declaration of Donald Bivens (December 15, 2016)
`Exhibit 2127
`Filov, V.A. (General Editor), Hydrocarcons Halogenated
`Hydrocarbons, Harmful Chemical Substances Handbook (1990)
`(English translation of Exhibit 2155)
`Exhibit 2128 Acute Toxicity Data, RTECS (2016)
`Exhibit 2129 Huttenlocher, Dietrich F., Chemical and Thermal Stability of
`Refrigerant-Lubricant Mixtures with Metals, prepared for The
`Air-Conditioning and Refrigeration Technology Institute (Oct. 9,
`1992)
`Standard Test Method for Acid and Base Number by Color-
`Indicator Titration, ASTM International (2006)
`Sheppard, William A., et al., Organic Fluorine Chemistry (1969)
`Exhibit 2131
`Exhibit 2131A Sheppard, William A., et al., Organic Fluorine Chemistry (1969)
`Exhibit 2132
`Chambers, Richard D., Fluorine
`in Organic Chemistry,
`Interscience Monographs on Organic Chemistry (1973)
`Exhibit 2132A Chambers, Richard D., Fluorine
`in Organic Chemistry,
`Interscience Monographs on Organic Chemistry (1973)
`Chambers, Richard D., Fluorine in Organic Chemistry (2004)
`Chambers, Richard D., et al., Nucleophillic Reactions of
`Fluorinated Alkenes, Topics in Current Chemistry, Vol. 192
`(1997)
`Exhibit 2134A Chambers, Richard D., et al., Nucleophillic Reactions of
`Fluorinated Alkenes, Topics in Current Chemistry, Vol. 192
`(1997)
`Chambers, Richard D., et al., Reactions of Novel Unsaturated
`Fluorocarbon, Journal of Fluorine Chemistry (2000)
`Exhibit 2135A Chambers, Richard D., et al., Reactions of Novel Unsaturated
`Fluorocarbon, Journal of Fluorine Chemistry (2000)
`
`Exhibit 2133
`Exhibit 2134
`
`Exhibit 2135
`
`
`
`9
`
`

`

`PGR2016-00011
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`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2136
`
`Exhibit 2137
`
`Exhibit 2138
`
`Bartlett, Sheena, et al., Reactions Involving Flouride Ion, Part 20,
`Competition between Isomerization and Nucleophilic Attack on a
`Perfluoroalkene (1980)
`Chambers Richard D., et al., Free Radical Chemistry, Part 9,
`Approaches to Fluorinated Polyethers Model Compound Studies
`(March 23, 1999)
`Exhibit 2137A Chambers Richard D., et al., Free Radical Chemistry, Part 9,
`Approaches to Fluorinated Polyethers Model Compound Studies
`(March 23, 1999)
`Chambers, Richard D., et al., Free-radical chemistry Part XII,
`trifluoroethene, Journal of Flourine
`Radical reactions of
`Chemistry (April 19, 2000)
`Exhibit 2139 Dyatkin, B.L., et al., Reactions of Fluoroolefins with
`Electrophilic Reagents, Flourine Chemistry Reviews, Vol. 3
`(1969)
`Exhibit 2140 HFO-1234yf encounters resistance as R-134a replacement for
`A/C, SAE International, available at http://articles.sae.org/8074/
`(April 14, 2010)
`Clayton Jr., J. Wesley, Fluorocarbon Toxicity and Biological
`Action, Toxicity of Anesthetics (1967)
`Clayton Jr., J. Wesley, The Mammalian Toxicology of Organic
`Compounds Containing Fluorine, Handbook of Experimental
`Pharmacology (1966)
`Commandeur, J.N.M., et al., Nephrotoxicity and Hepatotoxicity
`of 1,1-Dichloro-2,2-Difluoroethylene In the Rate: Indications for
`Differential Mechanisms of Bioactivation, Biochemical
`Pharmacology, Vol. 36 (June 24, 1987)
`E.W. Cook and J.S. Pierce, Toxicology of Fluoro-olefins, Nature,
`Vol. 242 (March 30, 1973)
`Exhibit 2145 Kennedy Jr., G. L., Toxicology of Fluorine-containing
`monomers, Toxicology, Vol. 21 (1990)
`Potter, C.L., et al., Effects of Inhaled Chlorotrifluoroethylene and
`Hexafluoropropene on the Rat Kidney, Toxicology and Applied
`Pharmacology (Jan. 9, 1981)
`Purchase, Iain F.H., Fraud, errors and gamesmanship in
`experimental toxicology, Toxicology (2004)
`Representative publications of Dr. Darryl DesMarteau relating to
`EPA and EPRI Initiatives
`
`Exhibit 2141
`
`Exhibit 2142
`
`Exhibit 2143
`
`Exhibit 2144
`
`Exhibit 2146
`
`Exhibit 2147
`
`Exhibit 2148
`
`
`
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`PGR2016-00011
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`
`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Exhibit 2150
`
`Exhibit 2151
`
`Exhibit 2154
`
`Exhibit 2155
`
`Exhibit 2149 Danishevskiy, S.L., et al., Toxicology of Some Fluoro-Organic
`Compounds, Foreign Technology Division (1989) - English
`Translation
`Exhibit 2149A Danishevskiy, S.L., et al., Toxicology of Some Fluoro-Organic
`Compounds, Foreign Technology Division (1989) - original
`Russian
`Final Test Results, Fluoroalkenes, EPA, Federal Register, Vol.
`52, No. 109 (June 8, 1987)
`Shabecoff, Philip, EPA Threatens to Suspend Approval of
`Pesticides Over Test Flaws, The New York Times (July 12, 1983)
`Exhibit 2152 U.S. Patent Publication No. 2011/0001080 A1 (Jan. 6, 2011)
`Exhibit 2153
`Standard Test Method for An American National Standard Acid
`and Base Number by Color-Indicator Titration, ASTM
`International, Designation 139/98 (2006)
`Protection of Stratospheric Ozone: Change of Listing Status for
`Certain Substitutes Under the Significant New Alternatives
`Policy Program, EPA, Federal Register, Vol. 80, No. 138 (July
`20, 2015)
`[Foreign Document] Vrednie Chemichescie Veshevsta,
`Galogenproisvodnie Ugledorov (1990) (original Russian of
`Exhibit 2127)
`Exhibit 2156 William B. Deichmann and Horace W. Gerarde, Toxicology of
`Drugs and Chemicals (1969)
`Exhibit 2156A William B. Deichmann and Horace W. Gerarde, Toxicology of
`Drugs and Chemicals (1969)
`EPA Health Effects Test Guidelines, Acute Inhalation Toxicity
`(August 1998)
`Papasavva, Stella, et al., Estimated 2017 Refrigerant Emissions
`of 2,3,3,3-tetrafluoropropene (HFC-1234yf) in the United States
`Resulting from Automobile Air Conditioning, Environmental
`Science Technology (Oct. 26, 2009)
`Vamvakas, Spyridon, et al., Metabolic Activation of the
`Nephrotoxic Haloalkene
`1,1,2-Trichloro-3,3,3-Trifluoro-1-
`Biochemical
`Conjugation,
`Propene
`By Glutathione
`Pharmacology, Vol. 38, No. 14, pp. 2297-2304 (1989)
`Smith, Ladd W., et al., Short-Term Inhalation Toxicity of
`Perfluoroisobutylene, Drug and Chemical Toxicology, 1525-
`6014
`(Online),
`available
`at
`http://www.tandfonline.com/loi/idct20 (1982)
`
`Exhibit 2157
`
`Exhibit 2158
`
`Exhibit 2159
`
`Exhibit 2160
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`Exhibit 2161
`Exhibit 2162
`
`Exhibit 2163
`Exhibit 2164
`Exhibit 2165
`
`Exhibit 2166
`
`Exhibit 2167
`
`Exhibit 2168
`
`Exhibit 2169
`Exhibit 2170
`Exhibit 2171
`Exhibit 2172
`Exhibit 2173
`Exhibit 2174
`
`Exhibit 2175
`
`
`
`
`
`
`
`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Declaration of Dr. Darryl Desmarteau
`Office Action Summary, Application No. 14/225,588, U.S.
`Patent and Trademark Office (Filed March 26, 2014)
`U.S. Patent No. 7,084,315 B2 to Corr et. al. (Aug. 1, 2006)
`Reserved
`U.S. Pat. App. No. 10/694,273 11-10-2008 - Rule 132
`Declaration of Rajiv Singh
`Excerpts of Deposition Transcript of Dr. Rajiv R. Singh (Sep. 17,
`2011) from litigation in the Eastern District of Pennsylvania
`between Arkema and Honeywell, Civ. A. No. 2:10-cv-2886
`Declaration of Joseph Posillico in support of Patent Owner’s
`Motion for Leave to Request a Certificate of Correction
`Patent Owner’s Proposed Request for a Certificate of
`Correction
`U.S. Provisional Patent Application No. 60/693,853
`U.S. Patent Application No. 11/475,605
`U.S. Patent Application No. 11/850,025
`U.S. Provisional Patent Application No. 60/658,543
`Excerpts of the Prosecution History of U.S. Patent No. 9,157,017
`Request for Certificate of Correction for U.S. Patent No.
`9,157,017 and Accompanying Papers
`Petition Under 37 CFR § 1.182 to Hold Final Written Decision in
`Abeyance Pending The Decision on Patent Owner’s Petition
`Under 37 CFR § 1.181
`
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`PGR2016-00011
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`Date: March 23, 2022
`
`
`
`
`
`
`
`Patent Owner’s Eighth Am. Appendix of Exhibits
`
`Respectfully submitted,
`
`/s/ Noah Frank
`Gregg F. LoCascio, P.C. (Reg. No. 55,396)
`Noah Frank (Reg. No. 67,279)
`glocascio@kirkland.com
`noah.frank@kirkland.com
`KIRKLAND & ELLIS LLP
`1301 Pennsylvania Ave., N.W.
`Washington, DC 20004
`Telephone: (202) 389-5200
`Fax: (202) 389-5200
`Attorneys For Patent Owner
`
`
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`CERTIFICATE OF SERVICE
`The undersigned hereby certifies that a copy of the foregoing Patent Owner’s
`
`Eighth Amended Appendix of Exhibits and newly designated Exhibit 2175 were
`
`served on March 23, 2022, via electronic mail directed to counsel of record for the
`
`Petitioners:
`
`Mark D. Sweet
`
`Mark J. Feldstein
`
`Erin M. Sommers
`
`mark.sweet@finnegan.com
`
`mark.feldstein@finnegan.com
`
`erin.sommers@finnegan.com
`
`Charles W. Mitchell
`
`charles.mitchell@finnegan.com
`
`
`
`
`
`
`
`
`
`Arkema_PTAB@finnegan.com
`
`/s/ Noah Frank
`Noah Frank
`
`
`
`
`
`
`
`