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~ Universily of Colorado Anschutz Medical Campus
`
`Webmail lilil, I UCD Acee!>!> lilil, I Cann 1!> lilil, I Quick Linb
`
`.,.
`
`] Q.
`
`Department of Anesthesiology
`
`School of Medicine
`
`Home
`
`About ..,
`
`Education ..,
`
`Research & Innovation .., Clinical Care ..,
`
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`Home Research & Innovation
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`Basic Research Christians Lab
`
`Basic Research
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`Clambey Lab
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`Christians Lab
`Uw• Christians Mp_~
`
`Plimary Appointment: Professor. A nesthesiology
`seconda ry Appointme nt: Professor, Pathology
`ProfesSOf (apt.) fiir Expelimentelle und Klinische Pharmako logie und Toxikologie, Medizinische Hochschule
`H annover, Hannover, Germa ny
`
`Education
`
`• MD (hig hest honors, · summa cum laude"). Medizinische Hochschu le Ha nnover, Hannover. Germany
`• Ph D ("Hatlilitation"), Experimentelle u nd Klin ische Pharmakologie und To xiko logie , Medizin ische Hochschule Hannover, Hannove r,
`Germany
`• Post-Doctoral Fe llowships
`o Biopharmaceutical Sciences (Dr. LL Benet), UniVerstty of California, San Francisco
`o Cardiothoracic Surgery and Transplant Immunology (Dr. R.E_ Morris), Stanford UniVe rsity Medica l SChool
`• Reside ncies and Board Certifications:
`o Facharzt fiir Pharmako logie and Toxikologie, Medizinische Hochschule Hannover. Hannover. Germany
`o Facha rzt fiir Klinische Pharmakologie, Medizin isehe Hochschule Hannover, Hannover, Germany
`o Ame rican Board of Clinical Pharmacology
`
`Contact Information
`
`12705 E Montview Blvd . Suite 200
`Aurora, Colorado 80045
`Direct Telephone (303) 724-5665
`Work: Telephone: (303) 724-5670
`Email: ~s@q@nschutz e<lu
`
`iC42 e'
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`Research Interests
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`Clinical Research
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`Research Leadership &
`Administration
`
`My research interests include p ha rmaco kinetk: and pharmacodynamic therapeutic drug monitoling, clink:al biochemistry. biochemical
`toxk:ology, and drug metabolism.
`
`Research Description
`My research has focused on the interactions between energy metabolism, mitochondrial metabolism and the mTOR pathway. This
`inctU<Jes the toxicoctynamk: inte ractions between calcineulin a nd mTOR pathway inhibitors, ageing, meta bolic disea ses, oxidative stress,
`ischemia/ reperfusion inj ury and d rug-coated coro nary ste nts and balloons.
`
`Publications
`Click here tor pr uwe ChliStians' pyblicaliQns on NCBI
`
`Department 01 AnesthesiOlogy
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`Anesthesiology (SOM)
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`o 2022 Illl...&:gents o f tne University .91J<.9.12!M19. a body corporate . All rights reserved.
`Accredited by the !:!jg her Learni ng Commission. All tradema rks a re reg iste red propeny of the University. Used by permission onty
`
`CMS login
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`https://medschool.cuanschutz.edu/anesthesiology/research-innovation/basic-research-pis/christians-lab
`
`9/7/2022
`
`Bausch Health Ireland Exhibit 2004, Page 1 of 1
`Mylan v. Bausch Health Ireland - IPR2022-01104
`
`

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