(12) United States Patent
`Say et al.
`
`USOO6175752B1
`(10) Patent No.:
`US 6,175,752 B1
`(45) Date of Patent:
`Jan. 16, 2001
`
`(54) ANALYTE MONITORING DEVICE AND
`METHODS OF USE
`(75) Inventors: James Say, Alameda; Michael F.
`Tomasco, Cupertino, both of CA (US);
`Adam Heller, Austin, TX (US); Yoram
`Gal, Kibbutz Yagur (IL); Behrad Aria,
`Alameda, CA (US); Ephraim Heller,
`Oakland, CA (US); Philip John
`Plante, Sunnyvale, CA (US); Mark S.
`Vreeke, Alameda, CA (US); Keith A.
`Esta, it S.E.edric
`s
`s
`(73) Assignee: Therasense, Inc., Alameda, CA (US)
`(*) Notice:
`Under 35 U.S.C. 154(b), the term of this
`patent shall be extended for 0 days.
`(21) Appl. No.: 09/070,677
`1-1.
`(22) Filed:
`Apr. 30, 1998
`
`(51) Int. Cl." .................................................... A61B 5/05
`(52) U.S. Cl. ........................... 600/345; 600/365; 128/903
`(58) Field of Search ..................................... 600/300-301,
`600/346, 306–309, 345-365, 372, 385-390;
`604/174–180; 128/897-898, 903, 904, 920
`O
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`Primary Examiner-Cary O’Connor
`ASSistant Examiner Michael Astorino
`(74) Attorney, Agent, or Firm Merchant & Gould P.C.
`(57)
`ABSTRACT
`An analyte monitor includes a Sensor, a Sensor control unit,
`and a display unit. The Sensor has, for example, a Substrate,
`a recessed channel formed in the Substrate, and conductive
`material disposed in the recessed channel to form a working
`electrode. The Sensor control unit typically has a housing
`adapted for placement on Skin and is adapted to receive a
`portion of an electrochemical Sensor. The Sensor control unit
`also includes two or more conductive contacts disposed on
`the housing and configured for coupling to two or more
`- 0
`contact pads on the Sensor. A transmitter is disposed in the
`housing and coupled to the plurality of conductive contacts
`for transmitting data obtained using the Sensor. The display
`unit has a receiver for receiving data transmitted by the
`transmitter of the Sensor control unit and a display coupled
`to the receiver for displaying an indication of a level of an
`analyte. The analyte monitor may also be part of a drug
`delivery system to alter the level of the analyte based on the
`data obtained using the Sensor.
`
`94 Claims, 26 Drawing Sheets
`
`SMALL RECEIVER
`AND
`DISPLAY UNIT
`
`48
`
`LARGE
`RECEIVER
`AND DISPLAY
`UNIT
`
`SENSOR
`CONTROL
`UNIT
`
`SENSOR
`
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`
`

`

`US 6,175,752 B1
`Page 2
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`7/1989
`10/1989
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`IPR2020-00910
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`

`

`US 6,175,752 B1
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`
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`

`US 6,175,752 B1
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