UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`APPLICATION NO.
`
`: 3.497.393 B2
`: 131548446
`
`DATED
`l'NV ENTORI S)
`
`.: July 30, 2013
`: i-fitesh Berra et :11.
`
`Page 1 of ]
`
`It is certified that error appears in the shave-identified pateni and that said Leners Patent is hereby corrected as shown below:
`
`Replace ‘“aOR::[}-R5" with -- uOR3:[}-R5 -- as follows:
`
`In the Specification:
`Col. 2. line 62:
`
`C01. 6, line 55; and
`
`In the Claims:
`
`Claim 1. cal. 19. line 4.
`
`Signed and Sealed this
`
`'I‘hirry-first Day of March. 2015
`
`WM/Kzés.
`
`Michelle K. Lev
`M! l’r'lur'fffiflla' Er'm'h'd' Starr! Man-m amt." limit-maul “mn-
`
`Liquidia - Exhibit 1016 - Page 1
`
`Liquidia - Exhibit 1016 - Page 1
`
`

`

`IN THE UNITED STA TES PA TENTAND TRADEMARK OFFICE
`
`Atty. Dkt. No. 0806134 162
`
`I'irst Inventor Name:
`
`llitesh BA'I‘RA
`
`['ille:
`
`AN IMPROVED PROCESS T0
`
`PREPARE 'l‘REPROS'I‘INlI .
`THE ACTIVE INGREDIENT
`1N REMODULIN'E‘
`
`Patent. No:
`
`Issue Date:
`
`Examiner:
`
`Art Unit:
`
`8,497,393
`
`780/2013
`
`Yevgeny Valenrod
`
`l62|
`
`Confirmation Number:
`
`109?.
`
`RE UEST FOR CERTIFICATE OF CORRECTION
`PURSUANT TO 3? C.F.R.
`1.323
`
`Commissioner for Patents
`[3.0. Box I450
`Alexandria. VA 223134450
`
`Commissioner:
`
`linelosed is a Certificate ofC‘orreetion, Form PTO—SW44. for United States Patent
`
`Number 8.497.393 issued July 30. 2013.
`
`Correction ofthe "CIORI :B-Rs" with ”(IOR‘jila-Rj -- in two instances in the
`
`specification. and in one instance in the claims, is requested.
`
`Applicants submit that the noted errors do not constitute new matter. and correction
`
`there-of would nol require reexamination.
`
`Pursuant to 37 (T.F.R. $51323. Applicants request that [he enclosed Certificate of
`
`Correction be approved.
`
`Since the noted errors are not the fault ofthe Patent Office. payment is enclosed ot‘the
`
`required fee ol‘$ | 00.00.
`
`4531524343851
`
`Liquidia - Exhibit 1016 - Page 2
`
`Liquidia - Exhibit 1016 - Page 2
`
`

`

`Atty. Dkt. No. 080618-1162
`
`l'he above-identified Fees are being paid by credit card via EI‘"S~Web.
`
`The Commissioner is hereby authorized to charge any additional Fees which may he
`
`required regarding this application under 3'." C.l-’.R. §§ 1.16-1. | ?._ or credit any overpayment,
`
`lo Deposit Account No. 19-0?41. Should no proper payment be enclosed herewith. as by the
`
`credit card payment instructions in EFS-Web being incorrect or absent. resulting in a rejected
`
`or incorrect credit card transaction, the Commissioner is authorized to charge the unpaid
`
`amount to Deposit Account No. 19-0141.
`
`Respectfully submitted.
`
`Date
`
` JAN 0 6 2015 'r ,g: -:__.._,-,:;" .3 -
`
`
`
`
`
`By V* ,rx---r.--"‘--'
`
`FOLEY & LARDN 1512. LLP
`Customer Number: 22428
`Telephone:
`[415} 984—9810
`Facsimile:
`(415)434-4511?
`
`3;": Alexey V. Saprigin tilted-‘51 -‘- >
`'
`' Agent for Applicants ""
`Registration No. 56.439
`
`483?-524fl4335.1
`
`Liquidia - Exhibit 1016 - Page 3
`
`Liquidia - Exhibit 1016 - Page 3
`
`

`

`INVENTORISJ
`
`Hitesh BATRA; Sudersan M. TULADHAR; Raju PENMASTA; David A.
`WALSH
`
`It is certified that an error appears or errors appear in the above-identified patent and that said Letters
`Patent is hereby corrected as shown below:
`
`Replace "oOR1zfi-R5" with --oOR2:B-R5 — as follows:
`
`Col. 2. line 62;
`Col. 6. line 55; and
`
`MODIFIED PTOISBr-M {Io-1.05]
`Approved for use through mraorzoo‘l’. OMB 0651 mm
`U 5. Patent ano Trademark Ofilce: US. DEPRRTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995. no persons are requneo to respond lo a coliecllon or information unless it displays a valid OMB control number
`Also Form PTO-1050
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`
`8’497393
`
`APPLICATION NO.
`
`13,548,448
`
`DATED
`
`7i30l’2013
`
`Claim 1, col. 19, line 4
`
`MAILING ADDRESS OF SENDER (Please do not use customer number below;
`Foley 8. Lardner LLP
`3000 K Street, N.W.. Suite 600
`Washington. DC. 20007-5109
`This collection of information is requ-reo Dy 3? CFR 1.322. 1.323. and ‘l 324. The information is requrreo to obtain or retain a benefit by the public. wnich
`Is to file {and by the USPTO to process} an application Confidentiality l5 governed lay 35 U 5.1:. 122 and 37 CFR 1 14. This collection IS estimated to
`Bite 1 0 hour to complete. Including gelhenng, preparing. and submittlrlg lhe completed application form to [he USPTO. Time wril vary depending upon
`the Ind-ind Liai case Any commenls on the amount oflrme you require [0 complete [his form annior suggestions for reducing this burden. should be sent
`lo the Chief Information Officer.
`US Patent and Trademark Office. U S. Department oiCommeroe. P 0 Box 1450.AIexandna,VA 22313-14150. DO NOT SEND FEES 0R
`COMPLETED FORMS TO THIS ADDRESS. SEND TO: Attention Certificate of Corrections Branch. Commissioner for
`Patents. PD. 3031450, Alexandria. VA 223134450.
`ll'you need assistance in completing the form. call I-aoO-PTO-QI‘QQ and select option 2
`
`4323-?563-3561 T
`
`Liquidia - Exhibit 1016 - Page 4
`
`Liquidia - Exhibit 1016 - Page 4
`
`

`

`Electronic Patent Application Fee Transmittal
`
`
`
`Filing Date: 13-Jul-2012
`
`Title of invention:
`
`PROCESS TO PREPARE TREPROSTINIL. THE ACIWE INGREDIENT IN
`REMODULINO
`
`
`
`
`First Named lnventorlllpplica nt Name:
`
`Hitesh Batra
`
`Stephen Bradford Maeb'lusllt’aren Walker
`
`Filed as Large Entity
`
`
`
`
`
`Filing Fees for Utility under 35 USC1‘l1la}
`
`Basic Filing:
`
`
`Pages:
`
`Claims:
`
`Miscellaneous-Filing:
`
`Patent-Appealls-and-Interference:
`
`Post-AIIowance-and-Post~lssuance:
`
`
`
`
`Certificate of Correction
`
`181 1
`
`1
`
`100
`
`100
`
`Liquidia - Exhibit 1016 - Page 5
`
`Liquidia - Exhibit 1016 - Page 5
`
`

`

`—-mm
`
`Miscellaneous:
`
`
`
`Sub-Total in
`950(5)
`
`
`
`
`Extension-of—Time:
`
`
`
`Total in USD (5)
`
`‘00
`
`Liquidia - Exhibit 1016 - Page 6
`
`Liquidia - Exhibit 1016 - Page 6
`
`

`

`Electronic Acknowledgement Receipt
`
`International Application Number:
`
`
`
` Confirmation Number: 2092
`
`i
`
`Title of Invention:
`
`PROCESS TO PREPARETREPROSTINIL, THE ACTIVE INGREDIENT IN
`
`REMDDUUNO
`
`
`
`First Named Inventormpplicant Name:
`
`Hitesh Batra
`
`“ Stephen Bradford MBEbiuS/Karenwalker
`Filer Authorized By: Stephen Bradford Maebius
`
`
`
`
`
`Attorney Docket Number:
`
`0806134 162
`
`13—JUL—201 2
`Filing Date:
`
`
`
`
`Time Stamp:
`
`12:40:07
`
`Payment information:
`
`Submitted with Payment I yes
`
`
`Payment Type
`Credit Card
`
`
`Deposit Account
`Authorized User
`
`The Director of the USPTO is hereby authorized to charge indicated fees and credit any overpayment as foilows:
`
`Liquidia - Exhibit 1016 - Page 7
`
`Liquidia - Exhibit 1016 - Page 7
`
`

`

`Docu ment
`File SizelBytes)!
`
`Number File Name Document Description
`Message Digest
`Part Azip
`{if appl.)
`2193011
`
`
`
`COdef
`Request for Certificate of Correction
`hanl FrnIIU'PLIP'tIIr-bd-Is I he! Ie-I-Ilt-ldo
`-II_L:
`
`Warnings:
`Information:
`
`fee-Infopdf
`Fee Worksheet (5306}
`r'<.lL . .I .-.- | {. Imam-1 lr't alw’lioll MrrIR..H -
`ll.v| L'
`
`Warnings:
`Information:
`
`
`
`New International Application Filed with the USPTO as a Receiging Office
`If a new international application is being filed and the international application includes the necessary components for
`an international filing datelsee PCT Article 11 and MPEP 181 O), a Notification of the International Application Number
`and ofthe International Filing Date {Form PCTIROH 05} will be issued in due course, subject to prescriptions concerning
`national security, and the date shown on this Acknowledgement Receipt will establish the international filing date of
`the application.
`
`
`
`Total Files Size (in bytes) 249985
`
`This Acknowledgement Receipt evidences receipt on the noted date by the USPTO of the indicated documents.
`characterized by the applicant, and including page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`New Applications Under 35 U.S.C.111
`If a new application is being filed and the application includes the necessary components for a filing date (see 37 CFR
`1.53Ibl-{d} and MPEP 506}, a Filing Receipt {37 CFR 1.54) will be issued in due course and the date shown on this
`Acknowledgement Receipt will establish the filing date ofthe application.
`
`National Stage of an International Application under 35 U.S.C. 371
`Ifa timely submission to enter the national stage ofan international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCTIDOIEOIQOEI indicating acceptance of the application as a
`national stage submission under 35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`Liquidia - Exhibit 1016 - Page 8
`
`Liquidia - Exhibit 1016 - Page 8
`
`

`

`
`Mail Stop 8
`
`.
`.
`REPORT ON THE
`Director of the U.S(.)ff';;::nt and Trademark
`FILING 0R DETERMINATION OF AN
`
`TRADEMARK
`ACTION REGARDING A PATENT OR
`9.0. Box I450
`Alexandria, VA 22313—1450
`
`
`
`In Compliance with 35 U.S.C. § 290 audfor 15 U.S.C‘. § 1116 you are hereby advised that a court action has been
`filed in the US. District Court for the District of New Jersey on the following:
`
`Trademarks or X Patents. {
`the patent action involves 3S U.S.C. § 292.)
`
`U.S. DISTRICT COURT
`
`
`TRE
`IN I
`DEFENDANT
`
`TEVA PHARMACEUTICALS USA, INC.
`
`
`TRADEMA ' L
`
`I
`
`1 US 6,765,117 '[32
`
`
`
`
`
`Case 3:14-cv—05498—PGS-LHG Document 3 Filed 09I02ll4 Page 1 of 1 PagelD: 125
`
`
`DATE FILED
`DOCKET NO.
`3:14-ev-05498-PGS—LHG 9f2f20l4
`
`PLAINTIFF
`UNITED THERAPEUTICS CORPORATION
`
`
`
`HOLDER OF PATENT OR TRADEMARK
`
`
`United Therapeutic Corporation
`
` DATE OF PATENT
`
`
`OR TRADEMARK
`
`July 20, 2004
`
`
`
`
`
`5 US 3.658.694 BI!
`February 25, 2014
`United Therapeutics Corporation
`
`
`
`
`DATE INCLUDED
`
`In the above—entitled case the followin_ mom: 5 {trademark s' have been included:
`INCLUDED BY
`
`TRADEMARK N . _
`
`OR TRADEMARK
`
`HOLDER OF PATENT OR TRADEMARK
`
`__ Amendment _ Answer _ Cross Bill
`
`__ Other Pleading
`
`
`
`In the ava—ntitled case the fOHIIWin eci im has been rendered or ’u- _erncnl issued:
`DECISIONIJUDGEMENT
`
`
`
`CLERK
`William T. Walsh
`
`(BY) DEPUTY CLERK
`5! Marlene Kalbach
`
`DATE
`9.1210014
`
`Copy l-“Upon initiation of action. mail this copy to Director Copy 3—Upon lcrminflfion of action. mail this copy to Director
`Copy Z—Upon filing document adding patcntts), mail this copy to Director Copy 4—Cnse file copy
`
`Liquidia - Exhibit 1016 - Page 9
`
`Liquidia - Exhibit 1016 - Page 9
`
`

`

`Case 3:14vcv-05499—PGS-LHG Document 2 Filed OQIOZIM Page 1 of 1 PagelD: 31
`
`TO‘
`'
`
`I
`
`I
`
`Mail Stop 8
`REPORT ON THE
`.
`FILING 0R DETERMINATION OF AN
`Dtreetor ofthe U.S(.)I;tatent and Trademark
`ACTION REGARDING A PATENT OR
`“'1
`TRADEMARK
`P-O- 3"" 145"
`Alexandria, VA 22313—1450
`
`In Compliance with 35 U.S.C. § 290 andfor 15 U.S.C. § 1116 you are hereby advised that a court action has been
`filed in the US. District Court for the District of New Jersey on the following:
`
`DATE I-ILED
`
`:14-ev—05499fiPG --LHG 9120014
`PLAINTIFF
`UNITED THERAPEUTICS CORPORATION
`
`
`
`Trademarks or X Patents. ( the patent action involves 3S U.S.C. § 292.)
`
`U.S. DISTRICT COURT
`TREHION. ELL
`DEFENDANT
`SAN DOZ, INC.
`
` DOCKET NO.
`
`
`I
`
`DATE OF PATENT
`Q h TRA I _
`. L
`
`July 30, 2013
`
`HOLDER OF PATENT OR TRADEMARK
`
`United Therapeutics Corporation
`
`
`
`
`
`
`
`In the ah I ve--entitied ease, the following patent a I trademark! st have been included;
`INCLUDED BY
`
`DATE INCLUDED
`
`DECISIONUUDGEMENT
`
`PATENT 0R
`TRADEMARK NO.
`
`DATE OF PATENT
`OR TRADEMA . K.
`
`HOLDER OF PATENT OR TRADEMARK
`
`_ Amendment
`
`_ Answer _ Cross Bill _ Other Pleading
`
`
`
`
`
`
`(BY) DEPUTY CLERK
`I
`CLERK
`Sf Marlene Kalbach
`William T. Walsh
`
`Copy l—Upon initiation of action. mail this copy to Director Copy 3—Upon termination of action. mail this copy to Director
`Copy Z—Upon filing document adding patent{s). mail this copy to Director Copy 4—-Case file copy
`
`DATE
`9/21’2014
`
`Liquidia - Exhibit 1016 - Page 10
`
`Liquidia - Exhibit 1016 - Page 10
`
`

`

`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`APPLICATION NO.
`
`: 8.497.393 B2
`: 132548446
`
`DATED
`lNV ENTORl S)
`
`.: July 30, 2013
`: Hiresl] Berra et :11.
`
`Page 1 Uf ]
`
`ll is certified that error appears in the above—identified patent and that said Letters Patent is hereby corrected as shown below:
`
`In the Claims:
`
`Replace the. term “‘tromethanine" with --trcmethamine-— as follows:
`
`Col. 19, claim 5, line 38;
`C01. 20. claim 13. line 55:
`
`Col. 20. claim 1?. line 66:
`Col. 2]. claim 19, line 6; and
`Col. 2]. claim 20. line 11.
`
`This certificate supersedes the Certificate. of Correction issued March 18. 2014.
`
`Signed and Sealed this
`
`Twenty-seventh Day of May, '20l4
`
`WM/(AL.
`
`Michelle K. Lur.‘
`fin-pm? Ua'u-rrw' ur'rira- i-‘lil'k-n' Klan-5 Pure”! and Hath-tumult Uflh't
`
`Liquidia - Exhibit 1016 - Page 11
`
`Liquidia - Exhibit 1016 - Page 11
`
`

`

`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`APPLICATION NO.
`
`: 8,497.39}. B2
`: ISIS-48446
`
`DATED
`l'NV ENTORl S)
`
`.: July 30, 2013
`: Hiresl] Barra et :11.
`
`Page 1 of ]
`
`1! is cert'rfied that error appears in the abeve—identifled patent and that said Letters Patent is hereby corrected as shown below:
`
`In the Claims:
`
`Replace the. term “‘tremethanine" with --tremethamine-— as follows:
`
`Col. 19, claim 5, line 38:
`C01. 20. claim 13. line 5;
`Col. 20. claim 17. line 66:
`Cal. 2|. claim 19, line 6; and
`
`Col. 21. claim 20, line 11.
`
`Signed and Sealed this
`
`Eighteenth Day of March, 20l4
`
`WM/(éa.
`
`”11'.th Dine-Mr Lif'fl'lt'
`
`Michelle K. Lei.-
`i-‘lil'k-n‘ Nam-s mel! mu." fl'mh'mm'fi Uflh'i
`
`Liquidia - Exhibit 1016 - Page 12
`
`Liquidia - Exhibit 1016 - Page 12
`
`

`

`IN THE UNITED STA TES PA TEN TAND TRA DWARK OFFICE
`
`Arty. Dkt. No. 0806l8-1162
`
`First Inventor Name:
`
`Hilcsh BATRA
`
`Title:
`
`AN IMPROVED PROCESS TO
`
`PREPARE TREPROSTINIL,
`THE ACTIVE INGREDIENT
`IN REMODULIN®
`
`Patent, 140.:
`
`Issue Date:
`
`Examiner.
`
`Art Unit:
`
`8,497,393
`
`730/2013
`
`Yovgeny Valenrod
`
`l621
`
`Confirmation Number:
`
`2092
`
`REQUEST FOR CERTIFICATE OF CORRECTION
`PURSUANT TO 37 C.F.R.
`1.323
`
`Commissioner for Patents
`PD. Box I450
`Alexandria, VA 223134450
`
`Commissioner:
`
`Enclosed, in duplicate. is a Certificate of Correction, Form PTO-SEEM, for United
`
`States Patent Number 8,497,393 issued July 30, 2013.
`
`Correction ofthe term"lrornethanine“ to ”trornetham ine“ in five instances in the
`
`claims is requested.
`
`Applicants submit that the noted errors do not constitute new matter. and correction
`
`thereof would not require reexamination.
`
`Pursuant to 3? C.F.R. §I .323, Applicants request that the enclosed Certificate of
`
`Correction be approved.
`
`Since the noted errors are not the fault oftho Patent Ofilce, payment is enclosed of‘the
`
`required fee of$l00.00.
`
`4841-6?5?-5063.1
`
`Liquidia - Exhibit 1016 - Page 13
`
`Liquidia - Exhibit 1016 - Page 13
`
`

`

`Atty. Dkt. No. 0806184162
`
`The aboVe-identified fees are being paid by credit card via BPS-Web.
`
`The Commissioner is hereby anthOrizcd to charge any additional fees which may be
`
`required regarding this application under 37 CPR. §§ 1.16- l .l 7. or credit any overpayment,
`
`to Deposit Account No. 19-07-11. Should no proper payment be enclosed herewith, as by the
`
`credit card payment instructions in EFS-Web being incorrect or absent, resulting in a rejected
`
`or incorrect credit card transaction. the Commissioacr is authorized to charge the unpaid
`
`amount to Deposit Account No. 19-074 I.
`
`Respectfully submitted,
`
`Date.
`
`my I} 3 lefl
`
`By
`
`FOLEY 3; LARDNER LLP
`Customer Number: 22428
`Telephone:
`(4! 5) 984-9810
`Facsimile:
`(4]5) 434-4507
`
`Aicxey v. Saprigin
`Agent for Applicants
`Registration No. 56.439
`
`4541 4? 57-5053. 1_
`
`Liquidia - Exhibit 1016 - Page 14
`
`Liquidia - Exhibit 1016 - Page 14
`
`

`

`MODIFtED PTOFSBJN {tint-05}
`Approved for title through 04501200? 0MB 0551-0033
`U S Felonl and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act 01 1995 no persons are required to respond to a collection of inlorrnation unless tt displays a valid OMB control number.
`Also Form PTO-105D
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`
`APPLICATION NO.
`
`DATED
`
`INVENTOR[S}
`
`.'
`
`'
`
`8,497,393
`
`131548.446
`
`78012013
`
`Hitesh BATRA; Sudersan M. TULADHAR; Raju PENMASTA, David A.
`WALSH
`
`
`
`It is certified that an error appears or errors appear in the above-identified patent and that said Letters
`Patent is hereby corrected as shown below:
`
`Replace the term "tromethanine" with --tromethamine — as follows:
`
`Col. 19. claim 5. line 38‘.
`Got. 20, claim 13. line 55;
`Col. 20.. claim 17. line E56;
`(20121. claim ‘IQ, line 6‘. and
`Col. 21. claim 20. line 11.
`
`MAILING ADDRESS OF SENDER {Please do not use customer number below).
`
`Foley 8i Lardner LLP
`3000 K Street. N.W.. Suite 600
`Washington. D.C. 20007-5143
`This collection or Information is required by 3? CFR 1.322. 1.323. and 1.33 The information Is required to obtain or retain a benefit by the public which
`is to file {and by the USPTD to process) an application Confidentiality is governed by 35 US C. 122 and 3? CFR 1.14. This collection is estimated to
`take 1.0 hour to complete. including gathering. preparing, and submitting the completed appticatlon Form to the USPTO Time will vary depending upon
`the indivioual case Any comments on the amount of time you require to complete this form enolor suggestions For reducing this burden. should be sent
`to the Chief Information Ofiicer.
`US. Patent and Trademark Olfice. US. Department or Commerce. P 0. Box 1450. Alexandria. VA 22313-1450. DO NOT SEND FEES OR
`COMPLETED FORMS TO THIS ADDRESS. SEND TO: Attention Certificate of Corrections Branch. Commissioner for
`Patents, P.O. Box1450. Alexandria. VA 22313-1450.
`ir‘you need assistance in completing the Tomi. call 1~800-PTO—9199 and select option 2.
`
`4345-1132504 55. 1
`
`Liquidia - Exhibit 1016 - Page 15
`
`Liquidia - Exhibit 1016 - Page 15
`
`

`

`Electronic Patent Application Fee Transmittal
`
`
`
`Filing Date: 13-Ju1-2o12
`
`Title of Invention:
`
`PROCESS TO PREPARE TREPROSTINIL. THE ACi'lVE INGREDIENT IN
`REMODULINO
`
`
`
`
`
`
`First Named Inventorlllpplica ht Name: Hitesh Batra
`
`Alexey Vi Sapriginf Karen Walker
`
`Attorney Docket Number:
`
`08061 8—1 162
`
`Filed as Large Entity
`
`
`
`
`
`Utility under 35 U5C111Ia) Filing Fees
`
`.
`
`.
`
`Sub-Total in
`
`Basic Filing:
`
`Pa gas:
`
`Claims:
`
`Miscellaneous-Filing:
`
`Petition:
`
`
`
`Patent-Appeals-and-Interference:
`
`Post-Al Iowa nce—and-Post—lssuance:
`
`Extension«of«Time:
`
`Liquidia - Exhibit 1016 - Page 16
`
`Liquidia - Exhibit 1016 - Page 16
`
`

`

`‘
`
`.
`
`Miscellaneous:
`
`Total in USD ($)
`
`
`
`Sub-Total in
`
`Liquidia - Exhibit 1016 - Page 17
`
`Liquidia - Exhibit 1016 - Page 17
`
`

`

`Electronic Acknowledgement Receipt
`
`International Application Number:
`
`
`
` Confirmation Number: 2092
`
`i
`
`
`
`Tltle of Inventlon:
`
`PROCESS TO PREPARETREPROSTINIL, THE ACTIVE INGREDIENT IN
`REMDDULiNO
`
`First Named Inventormpplicant Name:
`
`Hitesh Batra
`
`“ AlexeyV1 saprigianaren waiker
`
`
`
`Alexey V. Saprigln
`Filer Authorized By:
`
`
`
`
`Attorney Docket Number:
`
`0805134 162
`
`13—JUL—2012
`Filing Date:
`
`
`
`
`Time Stamp:
`
`13:00:28
`
`Payment information:
`
`Submitted with Payment I yes
`
`
`Payment Type
`Credit Card
`
`Deposit Account
`Authorized User
`
`
`
`File Listing:
`
`Document
`
`.
`
`File Size-(Bytes)!
`
`Multi
`
`Pages
`
`Liquidia - Exhibit 1016 - Page 18
`
`Liquidia - Exhibit 1016 - Page 18
`
`

`

`Request for Certificate of Correction
`
`|J I}!l-‘c'l|IrlDlil|-IiW+IiNh1‘ilILl-l fl Beirut-l
`'-'i|:".|'-.|
`
`Info rmation:
`
`sane .-
`
`Fee Worksheet (5306}
`
`fee-infopcif
`
`ll'g’lutitvllihhctll'31!3"51'.|'e".‘||'llil|_'n||!rlll?’lf
`
`Information:
`Total Files Size [in bytesii 12075?
`
`
`
`This Acknowledgement Receipt evidences receipt on the noted date by the USPTO of the indicated documents,
`characterized by the applicant, and including page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card. as described in MPEP 503.
`
`New Applications Under 35 U.S.C. 111
`lfa new application is being filed and the application includes the necessary components for a filing date (see 37 CFR
`1.53ibJ-{d} and MPEP 506}, a Filing Receipt {37 CFR 1.54) will be issued in due course and the date shown on this
`Acknowledgement Receipt will establish the filing date of the application.
`
`National Stage of an International Application under 35 U.$.C. 371
`If a timely submission to enter the national stage ofan international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCTIDDIEOIBOS indicating acceptance of the application as a
`national stage submission under 35 U.S.C. 33"! will be issued in addition to the Filing Receipt, in due course.
`
`New International Application Filed with the USPTO as a Receiving Office
`lfa new international application is being filed and the international application includes the necessary components for
`an international filing dateisee PCT Article 11 and MPEP1B1D). a Notification of the International Application Number
`and ofthe International Filing Date [Form PCTIROH 05} will be issued in due course, subject to prescriptions concerning
`national security, and the date shown on this Acknowledgement Receipt will establish the international filing date of
`the application.
`
`
`Liquidia - Exhibit 1016 - Page 19
`
`Liquidia - Exhibit 1016 - Page 19
`
`

`

`UNl‘l‘lil) S'l‘A'l'lES PA l‘liN'l‘ AND Tami-ammo: OFFICE
`
`
`
`UNITED S’I‘A’l‘l‘li DEPARTMENT OF COMMERCE
`Fain-d Stnlcs Patent and Trademark Ulric“
`fiddler-5.: CUMWISS iQNER I‘IOR PATENTS
`PD Hal l-J-5U
`Alexandria. V1 rglnin :5 I J-Hfiti
`n h'u'slsptagui
`
`APPI..1CATION NU.
`ISSUE UA'I'IL
`PATIfl‘s—I NU.
`ATTORNEY ULXiKl'i'l' N0.
`I..‘OT\‘]"]KMATIUN NU.
`
`ISIS-43.44 (I
`07.9230!!le 3
`34‘)? 3‘33
`0306 1 8-1 151
`1092
`
`12425
`
`TS'JU
`
`07!] I till I l 3
`
`FOLEY AND LARIJNER LLI’
`Slll‘l‘li 500
`3000 K S'I‘REE'I‘ NW
`WASl-IINGT( )N, DC 200"?
`
`The projected patent number and issue date are. specified above.
`
`ISSUE NOTIFICATION
`
`Determination of Patent Tenn Adjustment under 35 U.S.C. 154 (b)
`(application filed on or after May 29, 2000}
`
`The Patent Term Adjustment is 0 dayts). Any patent to issue from the above—identified application will include
`an indication of the adjustment on the front page.
`
`If :1 Continued Piosecution Application (CPA) was filed in the. above-identified application. the filing date that
`determines Patent Term Adjustment is the filing date of the most recent CPA.
`
`Applicant will. be able to obtain more detailed infonnation by accessing the Patent Application Information
`Retrieval (PAIR) WEB site (httpflpairnsptogov).
`
`Any questions reganding the Patent Term Extension or Adjustment determination should be dinected to the
`Office of Patent Legal Administration at (571)-272-7702. Questions relating to issue and publication fee.
`payments should be directed to the Application Assistance Unit [AAU] of the Office of Data Management
`[ODMJ at (571)—272—4200.
`
`APPLICANTlSi [Please see PAIR Willi silc It!Iptl'fpniralsptogov l'oradtlilionul applicants):
`
`Ilitcsh Batru. l'Icrndon. VA;
`Sudcrsan M. 'l‘uladhar. Silver Spring. MI):
`Raju l’cnmasta. llerndon. VA:
`David A. Walsh. Palmyra. VA;
`
`The United States represents the. largest, most dynamic marketplace in the world and is an unparalleled location
`for business investment, innovation. and commercialization of new technologies. The USA offers tremendous
`resources and advantages for those who invest and manufacture goods here. Through SelectUSA. Our nation
`works to encourage and facilitate business investment. To learn mom about why the USA is the best country in
`the world to develop technology, manufacture products, and grow your business, visit Selectflfifiggv.
`
`TRIO} rRev.
`
`lUI'tl‘J}
`
`Liquidia - Exhibit 1016 - Page 20
`
`Liquidia - Exhibit 1016 - Page 20
`
`

`

`OK TO ENTER: NW
`
`Atty. DkI.No.080618-1162
`
`IN THE UNITED STA TES PA TENTAND TRADEMARK OFFICE
`
`Applicant:
`
`Hltesh BATRA et al.
`
`Title:
`
`AN IMPROVED PROCESS TO
`
`PREPARE TREPROSTTNIL,
`THE ACTIVE INGREDIENT 1N
`REMODULING'U
`
`Appl. No.:
`
`0548,4146
`
`Filing Date;
`
`7/13/2012
`
`Examiner:
`
`Yevgeny Valenrod
`
`Art Unit:
`
`1621
`
`Confirmation
`Number:
`
`2092
`
`AMENDMENT UNDER 37 CFR 1.312
`
`Mail Stop Issue Fee
`Commissioner [or Patents
`PO. Box 1450
`
`Alexandria, VA 323l3-ld150
`
`Commissioner:
`
`Applicant acknowledges receipt of a Notice of‘Allowanee in the above—captioned
`
`application. Prior to payment ofthe issue fee. please amend the application as Follows:
`
`Amendments to the Claims are reflected in the listing of claims which begins on
`
`page 2 ofthis document.
`
`Remarks/Arguments begin on page 7 ofthis document.
`
`Please amend the application as follows:
`
`4620-80 94-9524J
`
`Liquidia - Exhibit 1016 - Page 21
`
`Liquidia - Exhibit 1016 - Page 21
`
`

`

`
`
`UNITED S'l‘A'i’liS PA'I‘IEN'I‘ AND TRADEMARK OFFICE
`UNITE!) STATES DEP$RTMENT DF COMMERCE
`lJnilcd Slates Pun-n! and 'I‘ratlemnrk 0m“
`J\ddicik- {TOMVIIQSIONER FOR Phi—17.51“"-
`i'.U Hull-15H
`Alcmmllln. Vlmnllu 33.31 L HS”
`www ibpn. . pm
`
`\PE’IJCA'HUN VG.
`|-'TI .ING iii-“ii
`I-7iiit9-1'i'N-LV'1FII INVENIT}R
`A |'Tl'.)ki\"l‘.\" Ul'X'Kl-I'I' Nfl.
`(‘l'iNf-'iiiN-T.-\']'1t IN NO.
`
`|3J545L44h
`”WINNIE
`Iiiluxh Balm
`0806184 |62
`30‘)!
`
`my mmmmup —
`SL] 1'['[{ 500
`m1 .Exiaura. YI‘LVE'II'iN‘a'
`
`3000 K STREET NW
`M1 ot'zoum
`
`.
`.
`,
`.
`.
`II'II‘I
`
`MAI]. DA'I'l-I
`DHjVi-‘Ji‘f Mt 11 1F.
`
`UNEffllfll .i
`['AI‘ER
`
`Please find below andlor attached an Office communication concerning this application or proceeding.
`
`The. time period for reply, it‘any, is. set in the attached communication.
`
`PTO]. {JIM (Rev. {HINT}
`
`Liquidia - Exhibit 1016 - Page 22
`
`Liquidia - Exhibit 1016 - Page 22
`
`

`

`
`Application No.
`Applicantfs)
`
`
` _ . 13r548.446 BATFIA ET AL.
`
`
`Response to Rule 312 Communication
`_
`.
`Examiner
`Art Unit
`
`— The MAILING DA TE of this communication appears on the cover sheet with the correspondence address —.
`
`YEVGENY VALENROD
`
`1521
`
`1. E The amendment iiied on 18 June 2013 under 37 OFF! 1312 has been considered. and has been:
`
`a) E entered.
`
`tr) [I entered as directed to matters of form not affecting the scope of the invention.
`
`c) El disapproved because the amendment was filed after the payment of the issue fee.
`
`Any amendment filed after the date the issue fee is paid must be acoompanied by a petition under 3? OFF! “313(c)(1)
`and the required fee to withdraw the application from issue.
`
`:4} El disapproved. See explanation below.
`
`e) [I entered In part. See explanation below.
`
`
`
`JYEVGENY \rALENFtODrr
`Primary Examiner. Art Unit 1621
`
`
`
` U S Paienl and Trademark Office
`PTOL—2T‘I (Rev. 04—01}
`Reponse to Rule 312 Communication
`Pan 0f Paper NO. 20130621
`
`Liquidia - Exhibit 1016 - Page 23
`
`Liquidia - Exhibit 1016 - Page 23
`
`

`

`PART II - FI‘LI‘IIS] 'I‘RANSMI'I'I'.'\I.
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`
`Liquidia - Exhibit 1016 - Page 24
`
`Liquidia - Exhibit 1016 - Page 24
`
`

`

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