Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 1
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 2
`
`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 3
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 4
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 5
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 6
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`cytopathic
`cytotechntW
`
`diagnosrs oi cytomegatovirus lCMV)
`
`liver, kidney. lung. salivary glands. and other organs
`
`urine; inclusion bodies in epithelial cells.especia|ly in
`children up to 3 mos; saliva
`
`specnic intranuclear and intracytoplasmtc inclusions in
`tissue sections
`
`tissue cultures from urine, throat cultures.lymphocytes.
`cervical secretion. biopsy and necropsy materials
`(sperm. breast milk)
`
`fluorescence
`
`was culture
`
`hybridization
`
`separation ot cellular from viral DNA
`
`complement binding reaction (CBR). passive
`hemoagglutination. immunotluorescence. neutralization
`test in tissue culturesdetermination ot lgM antibodies it
`active infection is suspected
`
`cy-lo-pathic lsi-ti‘i—path’ikt. Penaining to or exhibiting cytopa-
`
`cy-to-path-ogen-ic (si'to-path-t’i-Jen’ik). Pertaining to an agent
`or substance that causes a diseased condition in cells. in contrast
`to histologic changes; used especially with reference to effects
`observed in cells in tissue cultures.
`
`tsi’to-pa-tho-Ioj’ik.
`cytopathro-logic. cy-to-path-o-logical
`-Ioj’i-k2'il).
`l. Denoting cellular changes in disease. 2. Relating to
`c} tnputhology.
`A physician. usually
`(si’to-pa—thol'c'i-jist).
`cylto-pa‘lhol-o-gisl
`skilled in anatomical pathology. who is specially trained and
`experienced in cytopathology.
`cytopa-thol‘o'gy tsi’to-pa-thol'o~jéi.
`changes within individual cells or cell
`
`l. The study of disease
`types. 2. 5m c'\ll|lt.tlt\t:
`
`cyrtop-a‘thy tsi-top'aethé). Any disorder of a cell or anomaly of
`any of its constituents. lcyto~ + G. put/tar. disease]
`cytopemp-sis (si-tt‘J-pemp’sisl.
`SYN lliltl\c'\ltt\l'~
`/tt'ltl])i.\'. sending through]
`i.e.. hypocytosis. or a
`cyto-pe-nia tsi-to-pé’né-a). A reduction.
`lack of cellular elements in the circulating blood.
`[cyto- + G.
`[le’llill, poiet‘ty]
`
`lcyio- + G.
`
`Cy topha‘gy tsi-toi'fi-jél. Devouring of other cells by phago-
`cytes. [Cyl0v + U. plated. to devour]
`cytophan‘ere tsi’to-l‘a-néri. A radial spine seen in certain cysts
`of Surrvtcizrrit. as in rabbit and sheep tissue cysts.
`lcyto- + G.
`,i/muemx, Visible. evident. open]
`Gym-pharynx (si'to—l‘ar'inksi. An organelle in certain flagellatCs
`.iiid ciliates that serves as a gullet through which food material
`passes from the cytmtome to the cell
`interior: food passed is
`collected in food vacuoles.
`into which digestive enIymes are
`
`cyto-phiI-ic (si—tfi-lil'ikl.
`
`si'N i'Ji‘llvlt‘lx'
`
`Icyto- + G. phi/m.
`
`cy-tophotom-etry ttt’to-t‘t‘i-tuin’éaréi, A method or measuring
`the absorption of monochromatic light by \luincd microscopic
`structures leg. chromosomes. nuclei. whole L'L‘llsl With the aid of
`.i photoelectric cell: also used to measure cniitted light from such
`objects by fluorescence tn combination wrth selected fluoro—
`chrome dyes. lcyio. + G. pitch. light + mum”. iiieasurcl
`l‘ltiw c.. sis llti"\
`. mm. [I ~.
`
`C)” to-phy‘lac'lic lsi'tt‘i-l‘blak'tikl. Relating to cyttiphylaxis.
`t‘y-tophy-hxis tsi'to-tt-Iak'sisi. Protection of cells against lyric
`.tgciits. (cyto— + G. /)/l\ltl.\'l\’. a guarding]
`t')’ to-phy‘let-ic isi’tn-n-lct’tkl.
`Relating to the genealogy of .1
`tcll. lC}lU- + G. phi/t". a tribe]
`
`Gym-pipette (\‘l'tfi-pi-pel'l. A slightly curved. blunt end pipette
`usually made of glass and tilted with a rubber bulb to prm‘tdc
`
`gentle negative pressure for the collection of vaginal st
`for cytological examination.
`cy-to-plasm lsi'tL—Pplu/lttl. The substance of a cell. etc
`the nucleus. which contains \artnus organelles and tr
`Within a colloidal protoplasm. srr. \l st) protoplasm. liya
`cyttNiI.
`lcytti- + U. plui'mu. thing formed]
`ground-glass c.. uniform finely granular eosititiphilic c.
`licpatticytes tn carriers of hepatitis B Virus. and also in e:
`cells in keratoacanthoma.
`
`cytoplasmic txi-to-plaz'mtki. Relating to the C}l0rllil.\l
`C)’~t0-plaS-m0n tsi—to-plaz'mon). The total extranticleat
`information of a eukarytitic cell excluding that of ltlllll'
`and plastids.
`cy-to’plast tsi'to-plastl. The living intact cytoplastii that
`following cell enucleation. lcyto- + G. planar. formed]
`cyto-poi-evsis (si-tt'i—ptiy-é's‘isl. Formation of cells.
`icy
`parent. at making]
`cy~to-prep-a-ra~tion tsi’to-prep-a-ra'shuni. Laboratory
`tion of a cellular \pecimen for cytologic examination.
`cy-topy-ge tsi-to-pfjé). The anal orifice tcell “anus"; l
`certain structurally complex protozoa. such as the rumcn-i
`ciliates ot' herbivores.
`through which waste matter is
`Icytti» + G. ,iygt‘. buttocks]
`cy~to~ryc~tes. cy~tor~rhyc-les tsi-té-rik'tézi. Obsolete
`inclusion b(’lli(’$. under body. [cyto- + G. mykréy. a tliggt
`cytoscreener lsi'té-skrén'erl. SYN . ‘.lu'lt‘i.tllll‘llt",l\3
`
`cy-to‘sides tsi’to-sidzt. Ceramide disaccharides. SEE glyt
`golipid.
`cy-tosine (Cyt) ts‘i'to-sén). a pyrimidine found in tiuclei
`c. arabinoside (CA. AraCl. (l) a synthetic nucleoside us
`antimetabolite in the treatment of neoplasms: l2) incorri
`for arabinosylcytosine.
`c. ribonucleoside. 5w . \llilllll.‘
`cy~tovsis tsi-té'sis).
`l. A condition in which there is more
`usual number of cells. as in the c. of spinal fluid in near
`meningitis. 2. Frequently used with a prefixed combining
`a means of describing certain features pertaining to cel
`isocytosis. equality in size: polycytosis. abnomial
`inct
`number. lcyto- + G. ~t)\'i.\, condition]
`The tonofilaiitents.
`cy‘loskeI-e-ton tsi-tG-skcl’é-ton).
`desmin. neurotilamcnts. or other intermediate filaments so
`act as supportive cytoplasmic elements to stiffen cells or
`lIllC intracellular organelles.
`cy-to~smear isi’to-sméri.
`syN «filt'l‘r‘glt‘ on...»
`cy‘totsol
`lsi’tr'i-solt. Cytoplasni exclusive of the niitricl
`endoplasmic reticulum. and other membranous com;
`lcyto- + "sol." abbrev. of soluble]
`cy-to-soI-ic tst-tdsol’ik). Relating to or contained in the L
`cy-to-some tsi'té-soint.
`I. The cell body exclusive of the t
`2. Distinctive granule found in great alveolar (type ll) cell
`lung that releases pulmonary surfactant on the alveolar s
`syst multilamcllur body.
`[cyto- + G.
`i'r'mtu. body]
`cy-tos-tatsis (si-tos’ta-sis). The slowing of movement and
`ulation of blood cells. especially polymorphonuclear leul
`in the capillaries, as in a region of inflammation; obstruct
`capillary as the result of accumulated leukocytes.
`Icytt
`mum. standing]
`cy-tostat-ic tsT-lfi-stdl'lk). Characterized by cytosiasis.
`cyto-stome tsi’t6<stt‘iml. The cell “mouth" of certain c
`proto/oa. usually with a short gullet or cyttipharynx leadi
`into the organism. where it
`is collected into food vacuuli
`circulated inside the body. eventually to he excreted thro
`cytopygc. lcytri- + (i, \mnm. mouth]
`cytotac-tic tsi-tt'i-tak’tiki. Relating to cytntatis.
`cyetolax'ris. cyvtotaxia tsi-tfi-lttk'sis. ~tak’té~t’ii. The at
`tpositive c.) or repulsion tnegative c.) of cells for one 2
`Icyto— + G. ruxii. arrangement]
`.~\ person with
`cytotechnnlogist
`lsi'lti-tek-tiol'o-iisti.
`training in cytupathology who is; responsible for scrcenl
`smears and deteniiinrng which are negative and “hich
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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 8
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 9
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