PTO-1390 (Rev. 0908)
`Approved for use through 3/31/2010. OMB 06510021
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`TRANSMITTAL LETTER To THE UNITED STATES
`DESIGNATED/ELECTED OFFICE (DOIEO/US)
`CONCERNING A SUBMISSION UNDER 35 U.S.C. 371
`INTERNATIONAL APPLICATION NO.
`INTERNATIONAL FILING DATE
`
`TITLE OF INVENTION
`
`ATTORNEY’SDOCKET NUMBER
`i1jiSSJigigie/mg/Ifik1w137001215)
`12526296
`'
`’
`'
`. PRIORITY DATE CLAIMED
`02/000007
`
`NRF2 Screening Assays and Related Methods and Compositions
`APPLICANT(S) FOR DO/EO/us
`Matvey E. LUKASHEV
`Applicant herewith submits to the United States Designated/Elected Office (DO/EO/US) the following items and other information:
`
`This is a FIRST submission of items concerning a submission under 35 U.S.C. 371.
`
`This is a SECOND or SUBSEQUENT submission of items concerning a submission under 35 U.S.C. 371.
`
`This is an express request to begin national examination procedures (35 U.S.C. 371(f)). The submission must include items
`(5). (6), (9) and (21) indicated below.
`
`The US has been elected (Article 31).
`
`A copy of the international Application as filed (35 U.S.C. 371(c)(2))
`
`
`
`
`
`
`
`
`
`a. I: is attached hereto (required only if not communicated by the international Bureau).
`
`b. I:: has been communicated by the international Bureau.
`
`0. I:: is not required, as the application was filed in the United States Receiving Office (RC/US).
`
`
`
`An Eng iSh language translation of the international Application as filed (35 U.S.C. 371(c)(2)).
`
`is attached hereto.
`
`“TI
`__ has been previously submitted under 35 U.S.C. 154(d)(4).
`
`ndments to the claims of the International Application under PCT Article 19 (35 U.S.C. 371(c)(3))
`._
`
`
`
`
`
`
`
`
`
`
`
`are attached hereto (required only if not communicated by the international Bureau).
`
`have been communicated by the international Bureau.
`
`::I have not been made; however, the time limit for making such amendments has NOT expired.
`c.
`d. —-— have not been made and will not be made.
`
`
`
`
`
`
`An English language translation of the amendments to the claims under PCT Article 19 (35 U.S.C. 371(c)(3)).
`
`An oath or declaration of the inventor(s) (35 U.S.C. 371(c)( )).
`
`An English language translation of the annexes of the international Preliminary Examination Report under PCT
`Article 36 (35 U.S.C. 371(c)(5)).
`
`items 11 to 20 below concern document(s) or information included:
`
`
`
`, :I
`
`
`
`
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`
`
`
`
`An information Disclosure Statement under 37 CFR 1.97 and 1.98.
`
`An assignment document for recording. A separate cover sheet in compliance with 37 CFR 328 and 3.31 is included.
`
`A preliminary amendment.
`
`An Application Data Sheet under 37 CFR 1.76.
`
`A substitute specification.
`
`A power of attorney and/or change of address letter.
`
`A computer-readable form of the sequence listing in accordance with PCT Rule 13ter.3 and 37 CFR 1.821— 1.825.
`
`A second copy Of the published international Application under 35 U.S.C. 154(d)( ).
`
`A second copy of the English language translation of the international application under 35 U.S.C. 154(d)(4).
`
`This collection of information is required by 37 CFR 1.414 and 1491-1 .492. The information is required to obtain or retain a b enefit by the public, which is to file (and by the
`USPTO to pro cess) an application I Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.11 and 1.14. This collection is estimated to take 15 minutes to complete,
`including gathering information. preparing, and submitting the completed form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount
`of time you require to complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office. U.S.
`Department of Commerce, PO. Box 1450, Alexandria, VA 22313—1450. DO NOT SEND FEE 8 OR COMPLE mam Eflfibfifififl§END TO: Mail Stop PCT,
`Comnpaiwrloifftirfi, PO. Box 1450, AleXandria, VA 22313-1450.
`Page ’i of 3
`
`Mylan v. Biogen
`IPR 2018-01403
`
`Biogen Exhibit 2203
`Mylan v. Biogen
`IPR 2018-01403
`
`Page 1 of 10
`
`

`

`1. Online Credit Card Authorization Form in the amount of $ 234.00 to cover: Surcharge ($130); Excess claims
`($104); Petition for Extension of Time — 1 Mo ($130); and
`2. Petition for Extension of Time Under 37 CFR. 1.136(a). Documents filed electronically through EFS—Web.
`CALCULATIONS
`PTO USE ONLY
`
`
`
` a
`
`
`
`x $270
`
`
`
`
`
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`
`
`
`
`I
`
`PTO-1390 (Rev. 0908)
`Approved for use through 3/31/2010, OMB 0651-0021
`U.S. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
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`us. APPLlCATlON No. (if known, see 37 CFR1.5)
`lNTERNATiONAL APPLICATION NO.
`ATTORNEY’S DOCKET NUMBER
`
`
`12/526,296
`PCT/U82008/001602
`2159.3210001/JMC/M—R/KMH
`
`
`20.
`Other items or information:
`
`
`
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`
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` The following fees have been submitted
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`21. D Basic national fee (37 CFR 1.492(a)) ........................................................ $330
`
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`22. D Examinationfee(37 CFR1.492(C))
`if the written opinion prepared by [SA/US or the international preliminary examination report prepared
`
`
`by IPEA/US indicates all claims satisfy provisions of PCT Article 33(1)-(4) ............. $0
`Allothersrtuations ....,.........$220
`
`
`Search fee (37 CFR 1.4920»)
`23.
`
`
`
`if the written opinion of the ISA/US or the international preliminary examination report prepared by
`lPEA/US indicates all claims satisfy provisions of PCT Article 33(1)—(4) ................. $0
`
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`Search fee (37 CFR 1.445(a)(2)) has been paid on the international application to the USPTO as an
`international Searching Authority ................................................................... $100
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`international Search Report prepared by an iSA other than the US and provided to the Office or
`
`
`previously communicated to the US by the IB .................................................... $430
`
`All other situations ................................................................................................ $540
`
`
`
`TOTAL OF 21 22 and 23 =
`ditionai fee for specification and drawings filed in paper over 100 sheets (excluding sequence
`
`D Ad
`
`
`listing in compliance with 37 CFR 1.821(c) or (e) in an electronic medium or computer
`program listing in an electronic medium) (37 CFR 14920)),
`
`
`The fee is $270 for each additional 50 sheets of anaer or fraction thereof.
`
`
`RATE
`Number of each additional 50 or fraction
`Total Sheets
`Extra Sheets
`
`
`
`
`
`thereof (round up to a whole number)
`
`- 100 =
`/50 =
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`Surcharge of $130.00 for furnishing any ofthe search fee, examination fee, or the oath or declaration
`after the date of commencement of the national stage (37 CFR 1.492(h)).
`CLAIMS
`NUMBER FILED 7
`NUMBER EXTRA
`|
`NO
`
`RATE
`
`I
`
`39
`
`13000
`
`$ 104.00
`
`Independentclaims
`
`MULTIPLE DEPENDENT CLAlM(S) (if applicable)
`
`x
`
`$220
`
`$390
`+
`TOTAL OF ABOVE CALCULATIONS =
`
`
`E Applicant claims small entit status. See 37 CFR 1.27. Fees above are reduced by V2.
`I
`7
`SUBTOTAL =
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`TOTAL NATIONAL FEE
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`Processing fee of $130.00 for furnishing the English translation later than 30 months from the earliest
`
`claimed priority date (37 CFR 1.492(0).
`+
`
`Fee for recording the enclosed assignment (37 CFR 1.21(h)), The assignment must be accompanied
`by an appropriate cover sheet (37 CFR 3.28, 3.31). $40.00 per property
`+
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`
`
`
`TOTAL FEES ENCLOSED = 1 $ 234.00
`
`
`Amount
`
`
`refunded:
`
`
`I
`l
`l
`H
`I
`Amount to be
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`PTO~1390 (Rev. 09—08)
`Approved for use through 3/31/2010. OMB 0651-0021
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`Account No. 19-0036
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`Fees are to be charged to a credit card. WARNING: Information on this form may become public. Credit card inforrréation should not
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`to the USPTO. However, when paying the basic national fee, the PTO-2038 may NOT be faxed to the USPTO.
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`REGISTRATION NUMBER
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`SEND ALL CORRESPONDENCE TO:
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`1:. ohfi M. Covert
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`

`PTO/SB/22 (07-09)
`Approved for use through 07/31/2012. OMB 0651—0031
`U.S. Patent and Trademark Office; U.S. DEPARMENT OF COMMERCE
`Under the paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it displays a valid OMB control number. “men‘s-Nu,“v.
` \Ww‘xn , , :flnflhflm‘m‘
`
`
`PETITION FOR EXTENSION OF TIME UNDER 37 CFR 1.136(a)
`FY 2009
`
`{Fees pursuant to the Consolidated Aggropriations Act, ZQOQ‘QIR. 48183.)
`Ar19!i9s£is:!i9m93t--l2.4529229__..
`
`Docket Number (Optional)
`
`
`7
`
`21 59.3ilgggl/JMC1‘MAfiEEV/{Exw
`Filed August 7: 2009...
`
`For NRF2 Screening Assays and Related Methods and Compositions
`An Unit To Be Assigned
`This is a request under the provisions of 37 CFR 1.136(a) to extend the period for filing a reply in the above identified
`application.
`
`Examine, T0 Be ASSIgned
`
`The requested extension and fee are as follows (check time period desired and enter the appropriate fee below):
`
`E] One month (37 CFR1.17(a)(1))
`D Two months (37 CFR 1,17(a)(2))
`
`[:3 Threemonths(37CFR1.17(a)(3))
`
`Eee
`$130
`$490
`
`$1110
`
`Small Entity Fee
`$65
`$245
`
`$555
`
`$__1§Qfl___
`55
`
`$
`
`
`
`
`
`t
`i
`
`i
`
`i] Four months (37 CFR 1.17(a)(4))
`E
`1:]
`Five months (37 CFR 1.17(a)(5))
`g
`i [:1 Applicant claims small entity status. See 37 CFR 1.27.
`i E] A check in the amount of the fee is enclosed.
`i
`Payment by credit card. sametecaasaeaeasned.
`3 [j The Director has already been authorized to charge fees in this application to 3 Deposit Account.
`
`$865
`$1175
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`$
`55
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`$1730
`$2350
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`The Director is hereby authorized to charge any fees which may be required, or credit any overpayment, to
`Deposit Account Number m...
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`WARNING: Information on this form may become public. Credit card information should not be included on this form.
`Provide credit card information and authorization on PTO-2038.
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`l am the
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`[:1 applicant/inventor.
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`E] assignee of record of the entire interest. See 37 CFR 3.71.
`Statement under 37 CFR 3.73(b) is enclosed (Form PTO/SB/QB).
`
`E] attorney or agent of record. Registration Numbermeanness“...
`
`attorney or agent under 37 CFR 1.34.
`gegistration number if acting under 37 CFR 1.34 4.3.1152.—
`
`
`
`
` Signature
`
`
`JceaMCoverth W
`Typed or printed name
`
`W‘WM
`mmfl|flfifi>xhsens»...
`Januat‘t‘ 12,201 1
`Date
`
`(2021 371—2600
`Telephone Number
`
`..
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`NOTE: Signatures of all the inventors or assignees of record of the entire interest or their representative(s) are required. Submit multiple forms if more than one
`signature is required, see below.
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`
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`W»»\M~mwn
`i \\\\\\m\\\mm Wme\ummu\nm\vmeu
`D Totai of
`forms are submitted.
`This collection of information is required by 37 CFR 1.136(a). The information is required to obtain or retain a benefit by the public which imfile (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C, 122 and 37 CFR 1.11 and 1.14. This collection is estimated to take 6 minutes to
`complete, including gathering, preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any
`comments on the amount of time you require to complete this form and/or suggestions for reducing this burden, should be sent to the Chief information Officer,
`U.S. Patent and Trademark Office, US. Department of Commerce, RC). Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.O. Box 1450, Alexandria, VA 22313-1450.
`
`Page 4 of 10
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`If you need assistance in completing the form, call 1-800-PTO—9199 and select option 2.
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`

`

`
`
`Attomey’s Docket No.: 08201.0077-00000
`
`COMBTNED DECLARATTON AND POWER OF ATTORNEY
`
`As a below named inventor, I hereby declare that:
`
`My residence, post office address and citizenship are as stated below next to my name.
`
`1 believe l am the original, first and sole inventor ofthe subject matter which is claimed and for which a
`patent is sought on the invention entitled NRFZ SCREENING ASSAYS AND RELATED METHODS AND
`COMPOSITIONS, the specification ofwhich:
`
`is attached hereto.
`[]
`[X] was filed on August 7, 2009, as Application Seriai No. 12/52 2,26,.
`[]
`was described and claimed in PCT lntemational Application No.
`and as amended under PCT Article 19 on
`
`filed on
`
`.
`
`I hereby state that l have reviewed and understand the contents ofthe above—identified specification,
`including the claims, as amended by any amendment referred to above.
`
`l acknowledge the duty to disclose all information I know to be material to patentability in accordance with
`Title 37, Code of Federal Regulations, §l.56,
`
`l hereby claim the benefit under Title 35, United States Code, §l l9(e)(l) ofany United States provisional
`application(s) listed below:
`
`US. Serial No.
`60/888,921
`
`Filing Date
`February 8, 2007
`
`Status
`Expired
`
`1 hereby ciaim the benefit under Title 35, United States Code, §120 ofany United States application(s)
`listed below and, insofar as the subject matter of each ofthe claims ofthis application is not disclosed in the prior
`United States application in the manner provided by the first paragraph ofTitle 35, United States Code, §1 12, I
`acknowledge the duty to disclose all information I know to be material to patentability as defined in Title 37, Code
`of Federal Regulations, §l.56(a) which became available between the filing date ofthe prior application and the
`national or PCT international filing date ofthis application:
`
`US. Serial No.
`
`Filing Date
`
`
`Status
`
`I hereby claim foreign priority benefits under Title 35, United States Code, §1 19 ofany foreign
`application(s) for patent or inventor’s certificate or of any PCT international application(s) designating at least one
`country other than the United States of America listed below and have also identified below any foreign application
`forpatent or inventor’s certificate or any PCT international application(s) designating at least one country other than
`the United States of America filed by me on the same subject matter having a filing date before that ofthe
`application(s) ofwhich priority is claimed:
`
`
`
` Country Appiication No. Filing Date Priority Claimed
`
`18
`PCT/USZOOS/OO 1602
`February 8, 2007
`[X] Yes
`[ ] No
`
`Page 5 0f 10
`
`llSii3Svl
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`Page 5 of 10
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`

`

`
`
`Attorney’s Docket No: 082010077 «00000
`
`Combined Declaration and Power of Attorney
`Page 2 of2 Pages
`
`1 hereby appoint the following attorneys and/or agents to prosecute this application and to transact all
`business in the Patent and Trademark Office connected therewith:
`
`A11 Attomeys and Agents associated with
`
`Biogen Ides/Finnegan, Henderson, LL?
`
`PTO Customer Number 65,779
`
`Direct all telephone calls to Leslie A. McDonell at telephone number (617) 452-1600.
`
`Direct all correspondence to the following:
`
`Biogen Wee/Finnegan, Henderson, LLP
`
`PTO Customer Number 65,779
`
`For Assigned Inventions: i understand that the purpose of making this appointment is to permit
`prosecution ofpatent applications for the above~identified invention for the benefit ofmy assignee, and that this
`appointment does not create a personal attorney~client relationship between me and these appointees.
`
`l hereby declare that all statements made herein of my own knowledge are true and that all statements made
`on information and belief are believed to be true; and further that these statements were made with the knowledge
`that willful false statements and the like so made are punishable by fine or imprisonment, or both, under Section
`1001 ofTitle 18 ofthe United States Code and that such willful false statements mayjeopardize the validity ofthe
`application or any patents issued thereon.
`
`Full Name oflnvcntor: Matvey E. LUKASHEV
`
`
`":
`i
`ii
`"3
`“/ Date: $11056 ‘wiQ
`
`
`Tewksbuty, Masac . etts
`USA
`3 Louis Road, Tewksbury, MA 01876
`
`
`
`Inventor’s Signature:
`
`Residence Address;
`Citizenship:
`Post Office Address:
`
`Page 6 0f 10
`
`115835vl
`
`Page 6 of 10
`
`

`

`Electronic Patent Application Fee Transmittal
`
`Title of Invention:
`
`NRF2 SCREENING ASSAYS AND RELATED METHODS AND COMPOSITIONS
`
`_—
`
`U.S. National Stage under 35 USC 371 Filing Fees
`
`Description
`
`Fee Code
`
`Quantity
`
`Sub-Total in
`
`USD($)
`
`
`
`Basic Filing:
`
`Claims:
`
`Miscellaneous-Filing:
`
`Oath/decl > 30 months from priority date
`
`1617
`
`Patent-Appeals and Interference
`
`Post-Al|owance-and-Post-lssuance:
`
`Pa_e 7 0f 10
`
`Page 7 of 10
`
`

`

`Description
`
`Fee Code
`
`Quantity
`
`Sub-Total in
`
`USD($)
`
`364
`
`EXtenSion -1 month With so paid
`
`Extension-of—Time:
`
`1251
`
`Total in USD (5)
`
`Page 8 0f 10
`
`Page 8 of 10
`
`

`

`Electronic Acknowledgement Receipt
`
`Application Number:
`
`International Application Number:
`
`9227681
`
`12526296
`
`Confirmation Number:
`
`5197
`
`Title of Invention:
`
`NRF2 SCREENING ASSAYS AND RELATED METHODS AND COMPOSITIONS
`
`
`
`First Named Inventor/Applicant Name:
`
`Matvey E LUKASHEV
`
`Customer Number:
`
`22852
`
`Filer Authorized By:
`
`Attorney Docket Number:
`
`Receipt Date:
`
`Filing Date:
`
`Time Stamp:
`
`John Michael Covert
`
`08201.0077
`
`13-JAN-2011
`
`17:56:01
`
`Application Type:
`
`U.S. National Stage under 35 USC 371
`
`Payment information:
`
`Submitted with Payment
`
`Payment Type
`
`Payment was successfully received in RAM
`
`RAM confirmation Number
`
`Credlt Card
`
`$364
`
`5044
`
`Deposit Account
`
`Authorized User
`
`FHeLBfing:
`
`
`
`Document
`NumBage 9 0f 10
`
`Document Descri
`
`tion
`
`p
`
`File Size(Bytes)/
`Message Digest
`
`Pages
`Multi
`Part /.zip (if appl.)
`
`Page 9 of 10
`
`

`

`2159_3210001_DEC_F|L|NG.pd‘ df54005db52b07bd09593a283208bbbcb5
`
`703862
`
`Multipart Description/PDF files in .zip description
`
`Information:
`
`Fee Worksheet (PTO-875)
`
`fee-info.pdf
`
`21157190789a510f03116ea971a70a9a8b8
`ba18a
`
`This Acknowledgement Receipt evidences receipt on the noted date by the USPTO ofthe indicated documents,
`characterized by the applicant, and including page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`
`
`New Applications Under 35 U.S.C. 111
`lfa new application is being filed and the application includes the necessary components for a filing date (see 37 CFR
`1.53(b)—(d) and MPEP 506), a Filing Receipt (37 CFR 1.54) will be issued in due course and the date shown on this
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`National Stage of an International Application under 35 U.S.C. 371
`lfa timely submission to enter the national stage of an international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCT/DO/EO/903 indicating acceptance of the application as a
`national stage submission under 35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`New International Application Filed with the USPTO as a Receiving Office
`lfa new international application is being filed and the international application includes the necessary components for
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`
`Page 10 0f 10
`
`Page 10 of 10
`
`