Measure
`Start
`End
`Period
`Sort
`
`MOLECULE_TICKER
`RX_00161 Comdty
`RX_00161 Comdty
`RX_00161 Comdty
`RX_02533 Comdty
`RX_02533 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`
`TOTAL_INTEGRATED_AWP
`1/1/2009
`12/31/2018
`Per=Q
`Sort=A
`
`DRUG_NAME
`CAMPATH
`CAMPATH
`LEMTRADA
`GILENYA
`GILENYA
`COPAXONE
`COPAXONE
`COPAXONE
`COPAXONE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATOPA
`GLATOPA
`AVONEX
`AVONEX
`AVONEX PEN
`AVONEX PEN
`AVONEX PEN
`AVONEX
`AVONEX ADMINISTRATION PACK
`AVONEX ADMINISTRATION PACK
`REBIF
`REBIF
`REBIF
`REBIF REBIDOSE
`REBIF REBIDOSE
`REBIF REBIDOSE
`BETASERON
`BETASERON
`BETASERON
`BETASERON
`EXTAVIA
`EXTAVIA
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`
`MOLECULE_NAME
`ALEMTUZUMAB
`ALEMTUZUMAB
`ALEMTUZUMAB
`FINGOLIMOD HCL
`FINGOLIMOD HCL
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`INTERFERON BETA-1A
`INTERFERON BETA-1A
`INTERFERON BETA-1A
`INTERFERON BETA-1A
`INTERFERON BETA-1A
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1A/ALBUMIN
`INTERFERON BETA-1B
`INTERFERON BETA-1B
`INTERFERON BETA-1B
`INTERFERON BETA-1B
`INTERFERON BETA-1B
`INTERFERON BETA-1B
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`
`PRODUCT_INDICATOR
`B
`B
`B
`B
`B
`B
`B
`B
`B
`G
`G
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`G
`G
`G
`G
`G
`G
`G
`G
`
`1
`
`DRUG_STRENGTH
`10MG/ML
`30MG/ML
`12MG/1.2ML
`0.5MG
`0.5MG
`20MG
`20MG
`20MG/ML
`40MG/ML
`20MG/ML
`40MG/ML
`20MG/ML
`40MG/ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG
`30MCG
`30MCG
`22MCG/.5ML
`44MCG/.5ML
`8.8-22(6)
`22MCG/.5ML
`44MCG/.5ML
`8.8-22(6)
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`
`DRUG_PACKAGE_SIZE
`3.000
`1.000
`1.200
`28.000
`30.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`0.500
`1.000
`0.500
`1.000
`1.000
`4.000
`1.000
`4.000
`0.500
`0.500
`4.200
`0.500
`0.500
`4.200
`1.000
`1.000
`15.000
`5.000
`1.000
`1.000
`10.000
`10.000
`10.000
`10.000
`10.000
`10.000
`12.500
`12.500
`
`Biogen Exhibit 2109
`Mylan v. Biogen
`IPR 2018-01403
`
`Page 1 of 8
`
`

`

`Q1
`
`Q1_2009
`
`2009
`
`Q2
`
`Q2_2009
`
`2009
`
`Q3
`
`Q3_2009
`
`2009
`
`Q4
`
`Q4_2009
`
`2009
`
`Q1
`
`Q1_2010
`
`2010
`
`Q2
`
`Q2_2010
`
`2010
`
`Q3
`
`Q3_2010
`
`2010
`
`Q4
`
`Q4_2010
`
`2010
`
`Q1
`
`Q1_2011
`
`2011
`
`Q2
`
`Q2_2011
`
`2011
`
`17320236.16
`
`16628214.95
`
`15685683.57
`
`14395152.96
`
`14259017.23
`
`16765022.69
`
`15708932.64
`
`14625685.66
`
`15160479.09
`
`15301818.39
`
`9799981.06
`29051.32
`555867302.63
`
`8534248.84
`20119.23
`714873959
`
`4488093.2
`9018.48
`754733415.1
`
`274122.98
`
`716270837.7
`
`125314.33
`4049.96
`660368568.43
`
`70659.8
`1141.63
`695953315.57
`
`43105.76
`
`22226.37
`
`675401910.1
`
`674730358.39
`
`21795.05
`4055.96
`801523745.6
`
`7381.58
`
`871574804.4
`
`17704.96
`
`9990295.33
`
`59788499.46
`
`127340623.7
`
`193565.12
`678676999.3
`
`DRUG_FORM
`AMPULES INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`CAPSULE
`CAPSULE
`KITS INJECTABLE
`KITS INJECTABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`KITS INJECTABLE
`AUTO OR PEN INJECTOR
`PEN INJECTOR KIT
`PEN INJECTOR KIT
`KITS INJECTABLE
`KITS INJECTABLE
`KITS INJECTABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`KITS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`KITS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`
`MANUFACTURER_NAME
`BERLEX
`GENZYME
`GENZYME
`NOVARTIS
`NOVARTIS
`AVENTIS PHARMA
`REPACKER
`TEVA NEUROSCIEN
`TEVA NEUROSCIEN
`MYLAN
`MYLAN
`SANDOZ INC
`SANDOZ INC
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN PHARMA
`BIOGEN-IDEC
`REPACKER
`BIOGEN-IDEC
`BIOGEN-IDEC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`BAYER PHARM DIV
`BERLEX
`BERLEX
`BERLEX
`NOVARTIS
`NOVARTIS
`APP PHARMA
`BEDFORD LABS
`NOVAPLUS/SICOR
`OTN (JV LP)
`PFIZER/HOSPIRA
`TEVA PARENTERAL
`APP PHARMA
`BEDFORD LABS
`
`199053.8
`645358946.63
`
`254262.78
`779853437.32
`
`431318.82
`800693591.24
`
`352576.94
`775829082.26
`
`364825.75
`661621456
`
`336479.39
`645359287.21
`
`350438.22
`590203246.53
`
`292371.09
`595613568.1
`
`218690.06
`625709786.4
`
`36179.69
`54223965.74
`12679462.17
`236890339
`9342832.7
`
`33735.36
`63388326.25
`15265717.9
`277344647.38
`10993423.93
`
`30864.37
`64194127.52
`16449919.03
`296722652.72
`10678938.93
`
`32856.99
`59863934.2
`16195850.25
`281311635.3
`9071444.83
`
`77654.51
`53499989.14
`14265064.53
`249622264.7
`8880503.41
`
`84826.46
`51951868.89
`16672281.83
`264228040.4
`9443928.85
`
`106902.39
`48496043.72
`16399368.48
`252470416.75
`7983981.86
`
`58502.7
`48084478.86
`16851305.02
`252588276.59
`6968432.35
`
`78636.51
`49653557.3
`17027197.02
`267337474.22
`7464303.45
`
`85242.26
`53821233.62
`18292926.57
`283297593.21
`8106543.78
`
`276531978.7
`16162.46
`
`314377927.9
`29715.04
`
`344564408.86
`17043.5
`
`327763073.81
`13704.07
`
`263359748.17
`1404.56
`
`266350676
`2666.87
`
`245636668.38
`1351
`
`252423725.1
`375.39
`
`287781563.65
`
`315137074.85
`
`1065008.59
`
`2136224.56
`
`3036573
`
`4216438.98
`
`4528267.96
`
`5197077.87
`
`5811687.11
`
`1822054.8
`3914.27
`
`2384409.22
`14332.23
`
`2340602.68
`13248.72
`
`2006183.99
`4457
`
`1200381.86
`5897.5
`
`1109555.03
`7372.65
`
`-33097.25
`871444.6
`2339966.35
`1263024.43
`-1687.5
`
`16497
`517719.79
`1895415.2
`1197421.1
`-1080
`
`9403
`338987.55
`1642192.99
`1009035.72
`
`11293.8
`490494.06
`1002720.76
`988383
`
`10890.75
`741258.78
`98442.47
`519091.2
`-1080
`
`7054.5
`822585.91
`68067.05
`372211.08
`
`892297.47
`3304.8
`
`2820.7
`531555.2
`331952.81
`271352
`
`1015028.6
`3654.77
`
`499628.19
`202433.78
`373459.76
`1130
`
`2598912.53
`9811.25
`6350
`1246041.75
`697325
`1837728.04
`1337524.12
`179897.5
`
`1567021.07
`3095.05
`
`690641.25
`756787.5
`2092362.11
`1371198.62
`2857.84
`
`2
`
`Page 2 of 8
`
`

`

`Q3
`
`Q3_2011
`
`2011
`
`Q4
`
`Q4_2011
`
`2011
`
`Q1
`
`Q1_2012
`
`2012
`
`Q2
`
`Q2_2012
`
`2012
`
`Q3
`
`Q3_2012
`
`2012
`
`Q4
`
`Q4_2012
`
`2012
`
`Q1
`
`Q1_2013
`
`2013
`
`Q2
`
`Q2_2013
`
`2013
`
`Q3
`
`Q3_2013
`
`2013
`
`Q4
`
`Q4_2013
`
`2013
`
`Q1
`
`Q1_2014
`
`2014
`
`Q2
`
`Q2_2014
`
`2014
`
`Q3
`
`Q3_2014
`
`2014
`
`Q4
`
`Q4_2014
`
`2014
`
`Q1
`
`Q1_2015
`
`2015
`
`Q2
`
`Q2_2015
`
`2015
`
`17205548.2
`
`17198904.59
`
`16945923.56
`
`17496558.15
`
`16145175.59
`
`76252.46
`
`191914.16
`
`139334.82
`
`-6353.36
`
`-44476.72
`
`-8471.14
`
`230009400.44
`
`327643451.5
`
`252195435.22
`
`250921996.41
`
`281751729.65
`
`266883466.1
`
`278522760.67
`
`303386706.6
`
`312739291.1
`
`319498037.29
`
`308880739.84
`
`340931929.28
`
`358172228.39
`
`380664200.81
`
`2364.6
`
`7581.39
`
`979406794.49
`
`1053170540
`
`13214.87
`2092.58
`1208120534
`
`2536.2
`
`5072.4
`
`7580.02
`
`5071.98
`
`5217.8
`
`11731.98
`
`10418.64
`
`2727.1
`
`1282638566
`
`1291751300
`
`1210450679
`
`1235197841
`
`1204001938
`
`1131241425
`
`1045867826
`
`3575431.28
`404553626.68
`1913390.34
`
`12786394.72
`221908397.83
`235644156.6
`
`974251851.1
`98181405.01
`
`721809036.63
`443301014.4
`
`596302751.25
`615022466
`
`513381637.44
`693008259.49
`
`471447056.51
`788478497.59
`
`463837527.87
`884330545.57
`
`9242890.58
`1112640949
`
`10033559.07
`1300221775
`
`9054037.27
`661093216.64
`
`3594736.46
`714367410.28
`
`4315450.68
`621020945.55
`
`44150912.25
`
`171311749.93
`
`3537687.17
`563407723.24
`2559333
`231682305
`
`3318625.77
`453696156.1
`3085131
`269538239.55
`
`2159787.23
`407420496.5
`3025585.5
`305602733.5
`
`2123546.04
`384361471.88
`2799762
`313861645.64
`
`1697118.72
`353272729.17
`2655954
`322528092.4
`
`3494232.75
`310238444.1
`4508605.5
`318709224
`
`2017589.37
`300536208.79
`3203098.5
`354666940.1
`
`1476922.76
`281925397.4
`2345868
`351431495.85
`
`1402128
`275105219.75
`2185207.5
`348770730.36
`
`235957079.74
`
`295427058.67
`
`1005801.11
`84667925.9
`22134788.68
`338891025.1
`8341664.18
`
`746028.87
`96934508.46
`23716882.27
`357774566.61
`8465592.1
`
`644246.39
`49634481.44
`24778544.06
`369254410.82
`9504549.29
`
`223766.89
`52677997.54
`27486912.56
`395732773.49
`10157949.04
`
`266776.43
`48557093.37
`28481892.04
`403227531.3
`8846902.87
`
`337392.56
`46686302.14
`27652202.83
`375630691.58
`7477176.8
`
`314180263.49
`
`299282300.43
`
`271648683.78
`6406.84
`
`280027758.68
`2446.38
`
`280508341.49
`9646.12
`
`242333771.93
`4162.51
`
`272735
`41842933.49
`27153275.33
`379624327.38
`8051410.83
`123703.94
`765397.78
`377225.79
`228566770.73
`
`81789.07
`39770822.48
`24510196.18
`357515694.54
`4026050.54
`1970834.2
`18486247.13
`4489585.41
`214665935.64
`1223.19
`
`167992.96
`38599194.16
`22649970.16
`331982410.1
`2877930.33
`3644869.83
`37908503.78
`5029375.27
`191496679.62
`
`161382.19
`34283760.98
`19418666.61
`290234499.84
`2155460.33
`5159703.79
`54149484.96
`4600960.17
`184904320
`
`299630.97
`31521013.3
`22145030.62
`308724168.45
`3232068.01
`6485353.91
`71757904.47
`5324494.77
`158295193.38
`
`286750.18
`32083160.16
`21485241.02
`299483116.28
`2257926.79
`6988903.18
`81325465.55
`4557204.64
`187662889.41
`
`175792.26
`30277676.74
`20220188.62
`282163559.5
`2022000.58
`7558540.63
`89765266.8
`4543273.9
`180953755
`
`71879.02
`30394205.84
`21552290.23
`288508157.7
`2311047.58
`8509940.61
`97670826.77
`4100306.34
`172963168.6
`
`10487.66
`26012649.27
`20115893.89
`269647812.9
`1863659.71
`8270081.39
`98470719.54
`4172687.42
`182662147
`
`1524805.38
`
`251414836.1
`2247
`146096858.68
`156340891.1
`
`3023.9
`27694328.06
`19241874.86
`267226158
`2200065.14
`8015885.38
`102656253.58
`3765651.07
`187477689
`
`7922618.35
`
`8214763.37
`
`8660012.24
`
`9406371.45
`
`9897565.51
`
`9470471.72
`
`9205681.64
`
`968815.26
`1000.4
`
`852197.61
`642.96
`
`855350.8
`428.64
`
`632027.28
`
`743101.71
`
`559144.17
`
`595776.02
`
`8422923.63
`20164.08
`509246.79
`
`7968311.67
`32158.04
`586758.81
`
`8822315.81
`
`16406885.12
`
`19772085.62
`
`19937980.75
`
`17963510.43
`
`517563.02
`
`511203.55
`
`435069.91
`
`411430.79
`
`541720.2
`
`19018804.98
`9722.68
`598134.8
`
`19393870.16
`
`519086.07
`
`490744.84
`70717
`349440.3
`
`471905.17
`3071.19
`287257.5
`
`421368.23
`65056
`286581.6
`687.5
`
`332097.02
`297236.66
`137908.6
`
`379162.98
`64676.89
`282526.2
`
`348994.39
`191659.77
`222371.1
`
`288726.71
`224488.85
`158160.6
`
`266826.39
`263162.04
`167648.2
`
`267659.81
`165423.85
`123689.7
`
`197757.9
`291978.2
`69617.7
`
`203550.5
`319920.62
`12166.2
`
`194656.8
`316951.53
`4731.3
`
`196818.97
`400060.91
`690.09
`
`210024.82
`445403.66
`53396.1
`
`154132.57
`408247.85
`41229.9
`
`164692.59
`381233.68
`55423.8
`
`3
`
`Page 3 of 8
`
`

`

`Q3
`
`Q3_2015
`
`2015
`
`Q4
`
`Q4_2015
`
`2015
`
`Q1
`
`Q1_2016
`
`2016
`
`Q2
`
`Q2_2016
`
`2016
`
`Q3
`
`Q3_2016
`
`2016
`
`Q4
`
`Q4_2016
`
`2016
`
`Q1
`
`Q1_2017
`
`2017
`
`Q2
`
`Q2_2017
`
`2017
`
`Q3
`
`Q3_2017
`
`2017
`
`Q4
`
`Q4_2017
`
`2017
`
`Q1
`
`Q1_2018
`
`2018
`
`Q2
`
`Q2_2018
`
`2018
`
`Q3
`
`Q3_2018
`
`2018
`
`Q4
`
`Q4_2018
`
`2018
`
`13875216.84
`6005391.59
`475322689.91
`
`10650587.86
`2007158.79
`497865201.7
`
`10819004.59
`1283382.26
`522278790.81
`
`11697575.17
`1048986.94
`564241984.15
`3537.9
`
`16125660.68
`722783.92
`575164606.53
`19020.84
`
`10562058.57
`375361.83
`576461675.38
`
`8329721.21
`206910.55
`586315243.71
`
`10989250.62
`121764.29
`607974690.28
`
`11366329.45
`28339.6
`616101879.16
`2727.09
`
`11955967.04
`27623.84
`613297486.93
`
`10013548
`31571.4
`655616205.36
`2368.6
`
`11369396.27
`14174.48
`658024941.6
`
`10886004.47
`7630.99
`648959317.82
`
`8903691.42
`5132.34
`637285004.91
`
`359893743.8
`935964856.82
`
`320443067.2
`954354548.42
`
`269741512.62
`1004877280
`
`232471081.56
`1038537200
`
`222231610.29
`1052072846
`
`210425073.4
`1052782926
`
`196840338.93
`1078134088
`
`191082538
`1095034537
`
`186205423.44
`1113978782
`
`56631221.9
`
`61112666.35
`
`68225319.02
`
`72016548.91
`
`74579762.59
`
`71168012.91
`
`64665708.59
`
`62789189.38
`
`62026960.66
`
`253223193.4
`
`6612.16
`247803890.54
`
`168884616.43
`969203585.47
`3712106.78
`74523301.66
`57562713.79
`
`2003.99
`259090865
`
`6572615.71
`309603908.73
`
`2429494.89
`314428184.1
`
`5226.39
`255413537.38
`10575.99
`1055123.31
`314234335.44
`
`6010.94
`250133554.65
`
`12912.94
`249189379.91
`
`477120.52
`322675377
`
`558430.92
`325076507.3
`
`523567.66
`324688144.51
`
`134315.26
`217781586.61
`322444.5
`308073.62
`284389763.15
`
`464706.5
`213082250.1
`1553800.5
`129776.11
`279291354.72
`
`265088.52
`207093309.46
`1259443.5
`7544.49
`269801362.42
`
`188003.81
`196924995.26
`802179
`108427.69
`257587938.39
`
`151487874.39
`890189802.86
`7322059.67
`128625884.32
`53913420.56
`37754.6
`328869.26
`205700828
`1031373
`67606.8
`269458822.55
`
`148591096.16
`865625670.51
`8412646.03
`146753109
`51297174.07
`2354456.25
`216452.36
`204249424.63
`793191
`
`263031642.69
`
`26061267.18
`19302964.21
`256484400.54
`2185899
`8438837.7
`108533554.23
`5063924.75
`193128530
`
`25717654.95
`18924541.63
`256769210
`1928204.38
`9555531.38
`113757832.18
`4123389.63
`193196826.53
`
`26695093.2
`18704593.09
`244544195.88
`2633786.42
`9003768.38
`110772475.29
`5305633.11
`186835631.52
`
`26257872.76
`17287271.23
`243015727.46
`2293811.23
`9060502.66
`112059378.6
`4520986.84
`187227360.33
`
`19794988.01
`
`19348541.25
`
`21283181.1
`
`20357490.82
`
`580661.6
`
`781283.15
`
`617743.63
`
`756680.47
`
`1752.38
`25117307.21
`17587310.8
`245578638.82
`2138334.9
`9639208.15
`121272840.73
`4501466.59
`181539159.56
`1553.31
`
`19650058.71
`2144.42
`977119.78
`
`138177837.78
`775128496.79
`16193628
`149091745.75
`44937616.81
`18300591.93
`176946.06
`193951236.36
`772968
`51003.75
`252718934.38
`
`19325753.69
`17776604.37
`230563742.48
`1811941.82
`12622241.84
`137940015.21
`4074482.04
`156785821.81
`
`125166611.81
`711169509.28
`19434621.25
`151408872.24
`40968306.71
`21469200.59
`152816.99
`188079476.54
`677470.5
`
`246937427.57
`
`12343140.66
`16773253.96
`217337314.22
`1251062.16
`11785175.92
`131884924.1
`3290155.19
`138423773.28
`
`24920717.66
`18315910.92
`256391691.69
`2030571.47
`10904084.46
`134082937.1
`4387601.56
`175386389.65
`
`22423405.9
`17120863.63
`247475473.39
`2239380.67
`11003919.19
`136177150
`4880447.72
`176727595
`
`21460857.1
`18622886.27
`241645279.1
`1970549.62
`12033101.7
`133220143.58
`4297024.82
`179399380.83
`
`20854964.97
`18176676.4
`244389408.57
`1853692.89
`12160178.17
`133617285.1
`4329065.03
`170359945.24
`
`21077291.69
`18773047.55
`238902765.29
`1875147.49
`12196190.17
`135109757.78
`3686232.45
`174036904.51
`
`21714259.96
`18470934.92
`238181719.94
`1908993.21
`12480431.32
`135141989.3
`4493772.95
`180076746
`
`21769324.33
`18090808.16
`231487053.3
`1812977.09
`12360881.47
`137191459.77
`4341858.59
`171865092.3
`
`19128491.3
`
`17770605.79
`
`16926052.17
`
`15032175.04
`
`1193007.77
`
`633991.47
`
`1025006.04
`
`1052380.7
`
`15084630.84
`6321.22
`628458.05
`
`14451906.97
`26801.48
`224937.11
`
`13633512.44
`26801.48
`726063.57
`
`12605566.11
`20101.11
`935737.21
`
`11791730.85
`33501.85
`960419.75
`
`101202.9
`659692.34
`65562.3
`
`-2992.5
`625288.89
`105440.4
`
`-5319.98
`696847.61
`81783.9
`
`-1141.87
`685597.49
`81108
`
`-144.05
`401544.37
`194659.2
`
`222.62
`-22135.34
`224452.88
`
`445.24
`-1939.42
`554940.94
`
`5141.16
`
`183964.1
`
`259105.53
`
`30850
`
`12033.48
`
`1836
`
`158160.6
`
`202770
`
`264523.46
`
`490032.5
`
`254814.3
`
`178437.6
`
`114927.53
`
`4
`
`Page 4 of 8
`
`

`

`Measure
`Start
`End
`Period
`Sort
`
`MOLECULE_TICKER
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04585 Comdty
`RX_04585 Comdty
`RX_23190 Comdty
`RX_23190 Comdty
`RX_24384 Comdty
`RX_24384 Comdty
`RX_24384 Comdty
`RX_24384 Comdty
`RX_28506 Comdty
`RX_28506 Comdty
`RX_28506 Comdty
`RX_28506 Comdty
`RX_33868 Comdty
`
`TOTAL_INTEGRATED_AWP
`1/1/2009
`12/31/2018
`Per=Q
`Sort=A
`
`DRUG_NAME
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`TYSABRI
`TYSABRI
`AUBAGIO
`AUBAGIO
`DIMETHYL FUMARATE
`TECFIDERA
`TECFIDERA
`TECFIDERA
`PLEGRIDY
`PLEGRIDY
`PLEGRIDY PEN
`PLEGRIDY PEN
`OCREVUS
`
`MOLECULE_NAME
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`NATALIZUMAB
`NATALIZUMAB
`TERIFLUNOMIDE
`TERIFLUNOMIDE
`DIMETHYL FUMARATE
`DIMETHYL FUMARATE
`DIMETHYL FUMARATE
`DIMETHYL FUMARATE
`PEGINTERFERON BETA-1A
`PEGINTERFERON BETA-1A
`PEGINTERFERON BETA-1A
`PEGINTERFERON BETA-1A
`OCRELIZUMAB
`
`DRUG_STRENGTH
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG
`2MG
`2MG
`2MG
`2MG
`2MG
`2MG/ML
`2MG/ML
`2MG/ML
`300MG/15ML
`300MG/15ML
`14MG
`7MG
`
`120-240MG
`120MG
`240MG
`125MCG/0.5
`63-94MCG
`125MCG/0.5
`63-94MCG
`300MG/10ML
`
`DRUG_PACKAGE_SIZE
`12.500
`12.500
`12.500
`12.500
`15.000
`15.000
`15.000
`15.000
`15.000
`15.000
`10.000
`10.000
`12.500
`12.500
`15.000
`15.000
`10.000
`12.500
`15.000
`15.000
`15.000
`28.000
`28.000
`1.000
`60.000
`14.000
`60.000
`0.500
`1.000
`0.500
`1.000
`10.000
`
`PRODUCT_INDICATOR
`G
`G
`G
`G
`G
`G
`G
`G
`G
`G
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`N
`B
`B
`B
`B
`B
`B
`B
`B
`
`5
`
`Page 5 of 8
`
`

`

`Q1
`
`Q1_2009
`
`2009
`
`Q2
`
`Q2_2009
`
`2009
`
`Q3
`
`Q3_2009
`
`2009
`
`Q4
`
`Q4_2009
`
`2009
`
`Q1
`
`Q1_2010
`
`2010
`
`Q2
`
`Q2_2010
`
`2010
`
`Q3
`
`Q3_2010
`
`2010
`
`Q4
`
`Q4_2010
`
`2010
`
`Q1
`
`Q1_2011
`
`2011
`
`Q2
`
`Q2_2011
`
`2011
`
`283452
`146653.58
`726831.22
`446556.5
`224251.49
`
`-11744.45
`74023.47
`110559.88
`
`159896
`238241
`712577.99
`494769
`8351
`
`-39974.0
`300695.32
`657864.18
`462399.1
`
`230637.18
`577417.46
`505623.6
`-2496
`
`197076.92
`574032.07
`340053.4
`
`99210.2
`353752.71
`363817.8
`
`275969.39
`51816.63
`143820
`
`326150.78
`27723
`146115
`
`235310.65
`187660.98
`88740
`
`206071.01
`106456.01
`90270
`
`105749.04
`182235.94
`
`106423.25
`158017.48
`
`61365.14
`139188.79
`
`52158.72
`115015.03
`
`8919.2
`69768
`
`12832.49
`9120
`
`30405.96
`7296
`
`18743.41
`63840
`
`20887.89
`9120
`
`601152.67
`
`495073.99
`
`465894.92
`
`299049.44
`
`265928.05
`
`161077.88
`
`172302.43
`
`120912.09
`
`142170.69
`
`54823.92
`
`109413763.91
`
`120255086
`
`131789889.5
`
`134571945.47
`
`126550557.66
`
`127945171.56
`
`148207282.6
`
`152674085.69
`
`158299499.94
`
`169311540.92
`
`DRUG_FORM
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`TABLET
`TABLET
`BULK MISCELLANEOUS
`DELAYED RELEASE CAPSULE (ENTERIC COATED)
`DELAYED RELEASE CAPSULE (ENTERIC COATED)
`DELAYED RELEASE CAPSULE (ENTERIC COATED)
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`VIALS INJECTABLE
`
`MANUFACTURER_NAME
`NOVAPLUS/SICOR
`OTN (JV LP)
`PFIZER/HOSPIRA
`TEVA PARENTERAL
`APP PHARMA
`BEDFORD LABS
`NOVAPLUS/SICOR
`OTN (JV LP)
`PFIZER/HOSPIRA
`TEVA PARENTERAL
`IMMUNEX
`SERONO LABS
`IMMUNEX
`SERONO LABS
`IMMUNEX
`SERONO LABS
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`BIOGEN-IDEC
`ELAN PHARMA
`AVENTIS PHARMA
`AVENTIS PHARMA
`PROFESSIONAL CO
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN-IDEC
`BIOGEN-IDEC
`GENENTECH INC
`
`6
`
`Page 6 of 8
`
`

`

`Q3
`
`Q3_2011
`
`2011
`
`Q4
`
`Q4_2011
`
`2011
`
`Q1
`
`Q1_2012
`
`2012
`
`Q2
`
`Q2_2012
`
`2012
`
`Q3
`
`Q3_2012
`
`2012
`
`Q4
`
`Q4_2012
`
`2012
`
`Q1
`
`Q1_2013
`
`2013
`
`Q2
`
`Q2_2013
`
`2013
`
`Q3
`
`Q3_2013
`
`2013
`
`Q4
`
`Q4_2013
`
`2013
`
`Q1
`
`Q1_2014
`
`2014
`
`Q2
`
`Q2_2014
`
`2014
`
`Q3
`
`Q3_2014
`
`2014
`
`Q4
`
`Q4_2014
`
`2014
`
`Q1
`
`Q1_2015
`
`2015
`
`Q2
`
`Q2_2015
`
`2015
`
`87415.78
`102623.71
`31365
`
`92015.64
`76631.56
`33660
`
`84276.86
`115921.47
`27540
`
`97648.22
`97413
`26775
`
`71123.63
`92217.64
`50490
`
`71070.07
`125987.48
`10710
`
`214364.79
`40828.14
`64260
`
`145272.51
`-2700
`87975
`
`179032.33
`23850
`34425
`
`247381.86
`88055.92
`104040
`
`120445.38
`46775.24
`61965
`
`165646.7
`68513.81
`35190
`
`129290.41
`60071.35
`13770
`
`74810.6
`77959.4
`6885
`
`119192.12
`37020.94
`50490
`
`77946.06
`83450.47
`24480
`
`24730.8
`1824
`
`14078.04
`-7752
`
`52205.68
`8208
`
`77188.28
`18759.76
`
`29495.76
`15557.96
`
`20629.4
`20880.42
`
`30292.31
`27431.14
`
`19393.36
`33163.02
`
`19047.05
`10235.5
`
`11428.23
`19242.74
`
`8311.44
`22927.52
`
`20432.29
`24155.78
`
`11428.23
`28249.98
`
`11774.54
`19652.16
`
`37257.22
`
`1385.24
`26612.3
`
`216.5
`
`295270245.21
`
`351187556.43
`
`245960367.68
`
`261234260.13
`
`274576576.24
`
`279024950.26
`6603123.14
`1413773.34
`
`300214028.92
`25222653.66
`4828450.31
`
`283336464.52
`44690687.83
`7106350.71
`
`42791554.51
`236148931.3
`57754199.59
`7770408.44
`
`279992458
`9022302.79
`71702347.31
`8465021.71
`
`278310981.41
`1054938.65
`85915924.98
`9244839.63
`
`265458481.61
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`11168814.16
`
`259352180.23
`201280.12
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`
`262365007.25
`143013.60
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`14019188.07
`
`270399827.99
`28208.10
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`15847965.76
`
`287115897.52
`35777.09
`182012413.91
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`
`78060110.52
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`85125725.89
`
`66281119.95
`8345145.21
`273583028.34
`
`50843852.93
`8481745.84
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`
`48373835.17
`9390325.24
`509766857.27
`
`45059391.09
`10112590.91
`616183206.21
`
`43947648.88
`10361500.88
`693625049.45
`
`34376062.83
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`
`29086871.39
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`1445787.52
`26125333
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`
`29396972.01
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`6779059.14
`1157993.65
`50182750.82
`9231984.51
`
`7
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`Page 7 of 8
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`Q3
`
`Q3_2015
`
`2015
`
`Q4
`
`Q4_2015
`
`2015
`
`Q1
`
`Q1_2016
`
`2016
`
`Q2
`
`Q2_2016
`
`2016
`
`Q3
`
`Q3_2016
`
`2016
`
`Q4
`
`Q4_2016
`
`2016
`
`Q1
`
`Q1_2017
`
`2017
`
`Q2
`
`Q2_2017
`
`2017
`
`Q3
`
`Q3_2017
`
`2017
`
`Q4
`
`Q4_2017
`
`2017
`
`Q1
`
`Q1_2018
`
`2018
`
`Q2
`
`Q2_2018
`
`2018
`
`Q3
`
`Q3_2018
`
`2018
`
`Q4
`
`Q4_2018
`
`2018
`
`113730.12
`51255
`
`160257.77
`71910
`
`315854.21
`97645
`
`462000.42
`123845.74
`
`257996.69
`41310
`
`154225.05
`64260
`
`185349.66
`77500
`
`18870
`176243.47
`68850
`
`49725
`157484.35
`61965
`
`23152.5
`151778.52
`60435
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`29617.2
`131507.55
`80325
`
`-4528.01
`188598.93
`90270
`
`-1574.96
`129884
`58140
`
`36974.99
`232979.42
`76500
`
`5540.96
`54862.28
`
`81065.16
`
`-346.31
`39304.32
`
`45445.62
`
`54862.28
`
`41760.84
`
`102355
`
`51586.92
`
`44499.36
`
`77380.38
`
`1224
`61413
`
`9486
`43807.94
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`3672
`24565.2
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`4590
`16786.22
`
`308518428.76
`2950.60
`207249497.77
`19096085.34
`
`325610424.37
`5296.8
`239286825.43
`21310126.87
`
`326441471.1
`12697.09
`268945526.62
`23366884.76
`
`344156475.3
`144276
`295279225.15
`26103805.17
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`366041924.84
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`364091752.77
`
`305262633
`24658414.09
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`328232099.43
`25464227.09
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`372513175.29
`19083.48
`328248291.38
`24639691.58
`
`380248464.17
`
`343958886.55
`26455363.56
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`349225442.84
`48302.4
`347786564.78
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`
`337945098.81
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`331447565.05
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`341367808.41
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`311382024.20
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`366895370.74
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`377494273.1
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`396081830.72
`31740882.45
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`397147049
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`25110727.19
`10135120.50
`927928045.65
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`1059456.15
`61653539.24
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`24954702.90
`10845685.17
`943631642.35
`9691152.74
`782314.79
`67450942.28
`4949978.82
`
`27118383.42
`11270346.81
`931520605.76
`10052554.51
`$821,108.10
`77816864.39
`5536176.55
`
`26457858.77
`11442375.54
`939826895.35
`11082484.68
`733372.76
`82086523.25
`4477113.30
`
`24533743.35
`11113432.12
`964794518.56
`11308266.29
`578854.57
`84741576.22
`4324375.48
`
`20627004.51
`10924227.16
`933096841.71
`11439171.89
`443759.67
`82040296.67
`3107672.70
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`22539496.84
`11514167.71
`968240691.16
`9366386.81
`497204.85
`68410185.62
`2399952.98
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`20393907.46
`11616689.56
`1007533838
`10453263.8
`503279.62
`74336257.50
`2598685.85
`185272528.40
`
`22496641.35
`25373369.22
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`20188858.23
`14988888.05
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`12540053.64
`13206997.06
`1024998133 1012360179.80 1074085150.80 1100283878.30
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`289952.49
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`77465690.18
`78644973.82
`81798038.73
`80592705.75
`2675297.54
`2580434.89
`2540783.12
`2376539.88
`377071335.43
`443886547
`557571702.93
`624311062.15
`
`19801834.64
`14341665.67
`1088917616.8
`12479446.93
`321997.63
`74499464.46
`2017131.64
`708319177.03
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`310481284.93
`5499.84
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`31948015.25
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`17172182.93
`14573778.36
`1064234706.90
`12204175.12
`325376.22
`71378637.78
`1532369.06
`769657233.62
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`8
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`Page 8 of 8
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