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`‘Last hope‘ drug for prostate cancer patients is axed from the NHS | Daily Mail Online
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`‘Last hope‘ drug for prostate cancer patients
`is axed from the NHS, in a move doctors call -
`a ‘travesty’
`. Jetvana gives men with prostate cancer at least three months of life
`- But some men given the drug have survived three or more years
`. Cancer Drugs Fund plans to axe drug from its approved list from March
`They say it is not cost-effective and doesn't offer ‘sufficient clinical benefit‘
`. charities say the appraisal system for drugs is broken, failing patients
`. 40,000 men in Britain diagnosed each year, over 10,000 die from disease
`By JENNY HOPE MEDICAL CORRESPONDENT
`PUBLISHED: 08:04 EST, 9 January 2015 I UPDATED: 16:45 EST, 9 January 2015
`
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`A ‘last ditch’ drug for prostate cancer sufferers is to be axed from NHS use.
`Jevtana gives men with advanced disease at least three extra months of life — but some have
`survived three or more years.
`The Cancer Drugs Fund plans to remove the drug from its approved list effective from March
`because of weak cost-effectiveness.
`
`Although it will remain available for existing patients, doctors will be unable to prescribe it for
`hundreds of men with the disease.
`
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`A ‘last ditch‘ drug for prostate cancer sufferers is to be axed from NHS use from March this year. The
`chemotherapy drug Jevtana gives men with advanced disease at least three extra months of life - but some
`have survived for more than three years. Cancer charities say NHS England has failed patients (file photo)
`
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`More than 40,000 men are diagnosed with prostate cancer each year in Britain, and over 10,000 die
`their lovely daughters
`of it
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`Critics say the UK still lags behind Germany, France and Italy in prescribing life-prolonging
`Zissman shows off her
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`medicines to cancer patients and the situation will get worse.
`glittering band as she
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`Jevtana is among 25 drugs being re evaluated by the Cancer Drugs Fund, originally set up to
`http://www.dai|ym ail.co.uk/health/article-2903235/Last hope-drug-prostate-cancer-patients-axed-NHS-doctors-call-travesty.htm|
`
`'
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`AVENTIS EXHIBIT 2043
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`7/29/201 5
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`‘Last hope‘ dru for prostate cancer patients is axed lfnom the NHS | Daily Mail Online
`minidress to attend
`improve access to vital medicines in England, which will issue a full list of those being de-listed next
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`The decision to stop NHS use of Jevtana — it has already been rejected by the rationing body NICE
`— follows news that six breast cancer drugs prescribed for thousands of women are also set to be
`axed.
`
`Some men whose prostate cancer has spread will have no other treatment option.
`Dr Alison Birtle, consultant clinical oncologist at Lancashire Teaching Hospitals NHS Foundation
`Trust, said the decision was a travesty.
`She said ‘As a doctor who treats men with advanced prostate cancer, I am deeply saddened and my
`patients will be devastated by this decision.
`‘In my every day experience, Jevtana has given
`some men with advanced prostate cancer extra
`time.
`‘Some of the men that I started to treat with
`Jevtana 3 to 4 years ago are still alive today —
`and most importantly this time has been of good
`quality, allowing them to carry on doing the
`things they enjoy despite their cancer.’
`
`Jevtana, also called Cabazitaxel is a drug used
`to treat advanced prostate cancer when the
`cancer can no longer be controlled by
`hormonal therapy.
`Jevtana is given to people after they've already
`been treated with the chemotherapy drug
`
`The drug costs around £22,000 for a one-off
`course of treatment and about 500 patients a
`year have got it via the CDF.
`
`docetaxe"
`It is usually given in the chemotherapy day unit
`or during a short stay in hospital, by a
`
`Chemmherapy nurse‘
`Source: Macmillan
`
`The £280mil|ion a year Cancer Drugs Fund
`(CDF) which began in April 2011 has led to
`around 55,000 patients in England getting drugs
`banned on the NHS by Nice, the rationing body.
`The Government's aim, which was a Tory election pledge, was to enable NHS doctors to prescribe
`any drug if they believed a cancer patient could benefit.
`NHS England last year took over administration of the CDF, which is due to be wound up in 2016.
`Sandy Tyndale-Biscoe, of the prostate cancer patients’ charity Tackle, said ‘In recent years, earlier
`diagnosis and better treatments have led to great improvements in the treatment of advanced
`prostate cancer and in survival.
`
`Dr. Gopal Illlurli.-‘Via uala Llnlimiteclrcarlals
`
`Prostate cancer is the most common cancer in men in the UK, with over 40,000 new cases diagnosed every
`year. Picture, are human prostate cancer cells under the microscope
`
`‘By removing a key treatment available for this group of patients who are resistant to hormone
`therapies, NHS England has failed to honour its commitment to people with cancer who have no
`other options.’
`Owen Sharp, Chief Executive of Prostate Cancer UK said: ‘The very fact that cancer drugs face
`being struck off the government's additional funding pot in the first place is a symptom of a much
`deeper problem: the cancer drug appraisal and funding systems are broken.’
`CDF chair Professor Peter Clark said ‘We need to get maximum value for every pound we spend
`through the CDF.
`‘We can no longer sustain a position where we are funding drugs that don't offer sufficient clinical
`2
`htlp:V/www .dai Iymail .co. uk/health/anlli c|e—290323l5/Uast- hope-dnug- pnostate-cancer- patients-axied- N H S-doctons- cal I-travesty. hllm I
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`7/29/2015
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`‘Last hope’ dru for prostate cancer patients is axiett lfnom the NHS | Daily Mail Online
`benefit when drugs that will do more for patients are coming on stream.‘
`Heidi Montagin LA
`
`Cabazitaxel (Jevtana ®) - Cancer Information - Macmillan Cancer Support I never thought I d be
`
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