U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`____________________________________________
`
`BEFORE THE PATENT TRIAL AND APPEAL BOARD
`
`____________________________________________
`
`ResMed Inc.,
`Petitioner,
`v.
`New York University,
`Patent Owner,
`Case No. IPR2022-00989
`
`DECLARATION OF DR. KHOSROW BEHBEHANI
`IN SUPPORT OF PETITION FOR INTER PARTES REVIEW OF
`U.S. PATENT NO. 9,427,539
`
`ResMed Inc. Exhibit 1003
`Page 1 of 132
`
`

`

`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`V. 
`
`TABLE OF CONTENTS
`INTRODUCTION ........................................................................................... 1 
`I. 
`EXPERIENCE AND QUALIFICATIONS ..................................................... 1 
`II. 
`III.  STATUS AS AN INDEPENDENT EXPERT WITNESS .............................. 6 
`IV.  UNDERSTANDING OF GOVERNING LAW .............................................. 7 
`A.  Anticipation ........................................................................................... 7 
`B. 
`Obviousness ........................................................................................... 8 
`RELEVANT TIME PERIOD FOR THE OBVIOUSNESS
`ANALYSIS .................................................................................................... 10 
`VI.  MATERIALS RELIED ON IN FORMING MY OPINION ......................... 10 
`VII.  BACKGROUND ........................................................................................... 11 
`A.  Overview of the Technology ............................................................... 11 
`B. 
`Relationship Between Sleep and Breathing Patterns .......................... 19 
`C. 
`’539 Patent ........................................................................................... 22 
`D. 
`The Challenged Claims ....................................................................... 25 
`E. 
`Prosecution History ............................................................................. 26 
`VIII.  OVERVIEW OF THE PRIOR ART ............................................................. 26 
`A.  U.S. Patent No. 5,245,995 (Sullivan995) ........................................... 26 
`B. 
`PCT Application Publication No. WO 01/05460 A1
`(Sullivan460) ...................................................................................... 31 
`U.S. Patent No. 5,490,502 (Rapoport502) ......................................... 33 
`C. 
`IX.  LEVEL OF ORDINARY SKILL IN THE ART ........................................... 34 
`X. 
`CLAIM CONSTRUCTION ........................................................................... 34 
`
`i
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`Page 2 of 132
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`2. 
`
`3. 
`
`4. 
`
`XI.  OPINIONS ON GROUND 1: SULLIVAN995 IN VIEW OF
`SULLIVAN460 RENDERS OBVIOUS CLAIMS 1-2, 5-11, 13, 15-30 ...... 35 
`A.  Motivation to Combine ....................................................................... 35 
`B. 
`Reasonable Expectation of Success .................................................... 38 
`C. 
`Independent Claim 24 ......................................................................... 40 
`1. 
`Preamble: “A positive airway pressure system for
`treatment of a sleeping disorder in a patient, the system
`comprising:” ............................................................................. 40 
`24[a]: “a generator supplying airflow and applying a
`pressure to an airway of a patient;” ......................................... 42 
`24[b]: “a sensor measuring data corresponding to
`patient's breathing patterns from data indicate of the
`airflow supplied to the patient using at least one of a flow
`sensor or pressure sensor; and” ............................................... 43 
`24[c]: “a hardware processor analyzing the breathing
`patterns to determine whether breathing patterns
`indicate an asleep state or an awake state have
`occurred;” ................................................................................. 51 
`D.  Dependent Claims 25-30 ..................................................................... 59 
`1. 
`Claim 25: “The positive airway pressure system
`according to claim 24, wherein the hardware processor
`further analyzes the breathing patterns to determine
`whether breathing patterns indicative of a transition from
`an awake state to an asleep state have occurred.” .................. 59 
`Claim 26: “The positive airway pressure system
`according to claim 25, wherein the hardware processor
`determines that breathing pattern indicative of a
`transition from an awake state to an asleep state occurs
`when a regularity of breathing is detected.” ............................ 63 
`Claim 27: “The positive airway pressure system
`according to claim 25, the hardware processor
`determines that a transition from an awake state to an
`
`2. 
`
`3. 
`
`
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`ResMed Inc. Exhibit 1003
`Page 3 of 132
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`4. 
`
`5. 
`
`6. 
`
`asleep state occurs when a series of obstructions are
`detected.” .................................................................................. 67 
`Claim 28: “The positive airway pressure system
`according to claim 25, the hardware processor
`determines that a breathing pattern indicative of a
`transition from an awake state to an asleep state occurs
`when one of a plurality of indictors is present, the
`indicators being regularity of breathing and a series of
`obstructions.” ............................................................................ 71 
`Claim 29: “The positive airway pressure system
`according to claim 28, wherein the hardware processor
`sends a control signal to the generator to increase
`pressure provided to the patient when the hardware
`processor determines that a breathing pattern indicative
`of a transition from an awake state to an asleep state has
`occurred.” ................................................................................. 72 
`Claim 30: “The positive airway pressure system
`according to claim 29, wherein the generator is
`configured to use a ramp system to increase pressure.” .......... 74 
`Independent Claims 1 and 11 .............................................................. 75 
`1. 
`Preamble: “A positive airway pressure system for
`treatment of a sleeping disorder in a patient, the system
`comprising:” / “A method for treatment of sleeping
`disorder in a patient using a positive airway pressure,
`the method comprising:” .......................................................... 75 
`1[a]/11[a]: “a generator supplying airflow to an airway
`of a patient;” / “supplying an airflow to an airway of a
`patient using a flow generator;” ............................................... 75 
`1[b]/11[b]: “one or more flow sensors measuring data
`corresponding to the supplied airflow; and” / “measuring
`data corresponding to changes in flow or pressure of the
`airflow supplied to the patient using at least one of a flow
`sensor or a pressure sensor;” ................................................... 76 
`1[c]: “at least one hardware processor,” ................................. 76 
`
`E. 
`
`2. 
`
`3. 
`
`4. 
`
`
`
`iii
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`ResMed Inc. Exhibit 1003
`Page 4 of 132
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`5. 
`
`6. 
`
`7. 
`
`1[d]: “wherein the hardware processor receives the
`measured data from the one or more flow sensors and
`provides operational control signals to the generator,” .......... 76 
`11[c]: “analyzing, using a hardware processor, the
`measured data to determine whether the data includes
`breathing patterns indicative of at least one of an awake
`state or an asleep state;” ........................................................... 76 
`1[e]/11[d]: “wherein the hardware processor analyzes
`the measured data to determine whether a patient
`breathing pattern indicative at least one transition
`between an awake state and an asleep state has
`occurred, the hardware processor providing instructions
`to the generator to adjust the applied pressure in
`response to the patient's breathing patterns indicative of
`the at least one transition.” / “when a breathing pattern
`indicates a transition has occurred between an awake
`state and an asleep state, adjusting the supplied pressure
`to a first value. .......................................................................... 76 
`Dependent Claims 2, 5-10, 13, 15-24 ................................................. 80 
`1. 
`Claim 2: “The system according to claim 1, wherein the
`one or more flow sensors comprise at least one of an
`airflow sensor or a pressure sensor.” ....................................... 80 
`Claim 5, 17: “The system according to claim 1, wherein
`when the patient breathing pattern indicative of a change
`from the awake state to the asleep state has occurred, the
`hardware processor transmits an operational control
`signal to the generator to increase a pressure of airflow
`provided to the patient.” / “The method according to
`claim 11, further comprising controlling the generator to
`increase the supplied pressure when a breathing pattern
`indicative of one of an elevated upper airway resistance,
`hypopnea or a repetitive obstructive apnea is detected.” ......... 80 
`Claim 6, 19: “The system according to claim 5, wherein
`the hardware processor determines that the patient
`breathing pattern indicative of a change from the awake
`
`F. 
`
`2. 
`
`3. 
`
`
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`Page 5 of 132
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`state to the asleep state has occurred when the patient
`breathing pattern indicates regularity of breathing.” /
`“The method according to claim 18, wherein a transition
`from an awake state to an asleep state is determined to
`have occurred when a regularity of breathing is
`detected.” ................................................................................... 80 
`Claim 7, 20: “The system according to claim 5, wherein
`the hardware processor determines the patient breathing
`pattern indicative of a change from the awake state to the
`asleep state has occurred when the patient breathing
`pattern indicates a regular period of obstructions.” /
`“The method according to claim 18, wherein a transition
`from an awake state to an asleep state is determined to
`have occurred when a series of obstructions are
`detected.” ................................................................................... 80 
`Claim 8, 21: “The system according to claim 5, wherein
`the hardware processor monitors the measured data for
`at least one of a regularity of breathing or a regular
`period of obstructions.” / “The method according to
`claim 18, wherein a transition from an awake state to an
`asleep state is determined to have occurred when one of
`a plurality of indictors is present, the indicators being
`regularity of breathing and a series of obstructions.” .............. 81 
`Claim 9: “The system according to claim 1, wherein
`when the hardware processor determines that a patient
`breathing pattern indicative of a change from an asleep
`state to an awake state has occurred, the hardware
`processor transmits an operational control signal to the
`generator to decrease a pressure of airflow provided to
`the patient.” ............................................................................... 81 
`Claim 10: “The system according to claim 1, wherein
`when the hardware processor determines that a
`breathing pattern indicative of one of an elevated upper
`airway resistance, hypopnea or a repetitive obstructive
`apnea has occurred, the hardware processor transmits
`an operational control signal to the generator to increase
`the pressure supplied by the generator.” .................................. 82 
`
`4. 
`
`5. 
`
`6. 
`
`7. 
`
`
`
`v
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`8. 
`
`9. 
`
`Claim 13: “The method according to claim 11, further
`comprising placing a mask on a face of the patient and
`covering at least one of the mouth and the nose of the
`patient.” ..................................................................................... 86 
`Claim 15: “The method according to claim 11, further
`comprising controlling the generator to reduce the
`supplied pressure when a breathing pattern indicative of
`a change from an asleep state to an awake state is
`detected.” ................................................................................... 87 
`10.  Claim 16: “The method according to claim 11, further
`comprising controlling the flow generator to increase the
`supplied pressure when a breathing pattern indicative of
`a change from an awake state to an asleep state is
`detected.” ................................................................................... 88 
`11.  Claim 18: “The method according to claim 11, further
`comprising analyzing the breathing patterns to determine
`when the patient transitions from an awake state to an
`asleep state.” ............................................................................. 88 
`12.  Claim 22: “The method according to claim 18, further
`comprising increasing pressure provided to the patient
`when a determination of a transition from an awake state
`to an asleep state has occurred.” .............................................. 89 
`13.  Claim 23: “The method according to claim 18, further
`comprising ramping pressure provided to the patient
`when a breathing pattern indicative of a transition from
`an awake state to an asleep state has occurred.” ..................... 89 
`XII.  OPINIONS ON GROUND 2: RAPOPORT502 IN VIEW OF
`SULLIVAN460 RENDERS OBVIOUS CLAIMS 1-2, 5-11, 13, 15-30 ...... 89 
`A.  A POSITA Would Have Been Motivated to Combine ....................... 89 
`B. 
`A POSITA Would Have Had a Reasonable Expectation of
`Success ................................................................................................ 92 
`Independent Claim 24 ......................................................................... 94 
`
`C. 
`
`
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`vi
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`Page 7 of 132
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`

`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`1. 
`
`2. 
`
`3. 
`
`4. 
`
`Preamble: “A positive airway pressure system for
`treatment of a sleeping disorder in a patient, the system
`comprising:” ............................................................................. 94 
`24[a]: “a generator supplying airflow and applying a
`pressure to an airway of a patient” .......................................... 95 
`24[b]: “a sensor measuring data corresponding to
`patient's breathing patterns from data indicate of the
`airflow supplied to the patient using at least one of a flow
`sensor or pressure sensor; and” ............................................... 96 
`24[c]: “a hardware processor analyzing the breathing
`patterns to determine whether breathing patterns
`indicate an asleep state or an awake state have
`occurred;” ................................................................................. 97 
`D.  Dependent Claims 25-30 ..................................................................... 99 
`1. 
`Claim 25: The positive airway pressure system
`according to claim 24, wherein the hardware processor
`further analyzes the ................................................................... 99 
`Claim 26: The positive airway pressure system
`according to claim 25, wherein the hardware processor
`determines that breathing pattern indicative of a
`transition from an awake state to an asleep state occurs
`when a regularity of breathing is detected. ............................ 100 
`Claim 27: The positive airway pressure system
`according to claim 25, the hardware processor
`determines that a transition from an awake state to an
`asleep state occurs when a series of obstructions are
`detected. .................................................................................. 101 
`Claim 28: The positive airway pressure system
`according to claim 25, the hardware processor
`determines that a breathing pattern indicative of a
`transition from an awake state to an asleep state occurs
`when one of a plurality of indictors is present, the
`indicators being regularity of breathing and a series of
`obstructions ............................................................................. 102 
`
`2. 
`
`3. 
`
`4. 
`
`
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`Page 8 of 132
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`5. 
`
`6. 
`
`E. 
`
`Claim 29: The positive airway pressure system
`according to claim 28, wherein the hardware processor
`sends a control signal to the generator to increase
`pressure provided to the patient when the hardware
`processor determines that a breathing pattern indicative
`of a transition from an awake state to an asleep state has
`occurred.” ............................................................................... 102 
`Claim 30: The positive airway pressure system
`according to claim 29, wherein the generator is
`configured to use a ramp system to increase pressure ........... 102 
`Independent Claims 1 and 11 ............................................................ 103 
`1. 
`Preamble: “A positive airway pressure system for
`treatment of a sleeping disorder in a patient, the system
`comprising:” / “A method for treatment of sleeping
`disorder in a patient using a positive airway pressure,
`the method comprising” .......................................................... 103 
`1[a]/11[a]: “a generator supplying airflow to an airway
`of a patient;” / “supplying an airflow to an airway of a
`patient using a flow generator;” ............................................. 103 
`1[b]/11[b]: “a generator supplying airflow to an airway
`of a patient;” / “supplying an airflow to an airway of a
`patient using a flow generator;” ............................................. 103 
`1[c]: “at least one hardware processor,” ............................... 104 
`1[d]: “wherein the hardware processor receives the
`measured data from the one or more flow sensors and
`provides operational control signals to the generator,” ........ 104 
`11[c]: “analyzing, using a hardware processor, the
`measured data to determine whether the data includes
`breathing patterns indicative of at least one of an awake
`state or an asleep state;” ......................................................... 104 
`1[e]/11[d]: “wherein the hardware processor analyzes
`the measured data to determine whether a patient
`breathing pattern indicative at least one transition
`
`2. 
`
`3. 
`
`4. 
`5. 
`
`6. 
`
`7. 
`
`
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`Page 9 of 132
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`F. 
`
`2. 
`
`between an awake state and an asleep state has
`occurred, the hardware processor providing instructions
`to the generator to adjust the applied pressure in
`response to the patient's breathing patterns indicative of
`the at least one transition.” / “when a breathing pattern
`indicates a transition has occurred between an awake
`state and an asleep state, adjusting the supplied pressure
`to a first value.” ...................................................................... 104 
`Dependent Claims 2, 5-10, 13, 15-24 ............................................... 106 
`1. 
`Claim 2: The system according to claim 1, wherein the
`one or more flow sensors comprise at least one of an
`airflow sensor or a pressure sensor.” ..................................... 106 
`Claim 5, 17: “The system according to claim 1, wherein
`when the patient breathing pattern indicative of a change
`from the awake state to the asleep state has occurred, the
`hardware processor transmits an operational control
`signal to the generator to increase a pressure of airflow
`provided to the patient.” / “The method according to
`claim 11, further comprising controlling the generator to
`increase the supplied pressure when a breathing pattern
`indicative of one of an elevated upper airway resistance,
`hypopnea or a repetitive obstructive apnea is detected.” ....... 106 
`Claim 6, 19: “The system according to claim 5, wherein
`the hardware processor determines that the patient
`breathing pattern indicative of a change from the awake
`state to the asleep state has occurred when the patient
`breathing pattern indicates regularity of breathing.” /
`“The method according to claim 18, wherein a transition
`from an awake state to an asleep state is determined to
`have occurred when a regularity of breathing is
`detected.” ................................................................................. 107 
`Claim 7, 20: “The system according to claim 5, wherein
`the hardware processor determines the patient breathing
`pattern indicative of a change from the awake state to the
`asleep state has occurred when the patient breathing
`pattern indicates a regular period of obstructions.” /
`
`3. 
`
`4. 
`
`
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`“The method according to claim 18, wherein a transition
`from an awake state to an asleep state is determined to
`have occurred when a series of obstructions are
`detected.” ................................................................................. 107 
`Claim 8, 21: “The system according to claim 5, wherein
`the hardware processor monitors the measured data for
`at least one of a regularity of breathing or a regular
`period of obstructions.” / “The method according to
`claim 18, wherein a transition from an awake state to an
`asleep state is determined to have occurred when one of
`a plurality of indictors is present, the indicators being
`regularity of breathing and a series of obstructions.” ............ 107 
`Claim 9: : “The system according to claim 1, wherein
`when the hardware processor determines that a patient
`breathing pattern indicative of a change from an asleep
`state to an awake state has occurred, the hardware
`processor transmits an operational control signal to the
`generator to decrease a pressure of airflow provided to
`the patient.” ............................................................................. 107 
`Claim 10: “The system according to claim 1, wherein
`when the hardware processor determines that a
`breathing pattern indicative of one of an elevated upper
`airway resistance, hypopnea or a repetitive obstructive
`apnea has occurred, the hardware processor transmits
`an operational control signal to the generator to increase
`the pressure supplied by the generator.” ................................ 108 
`Claim 13: “The method according to claim 11, further
`comprising placing a mask on a face of the patient and
`covering at least one of the mouth and the nose of the
`patient.” ................................................................................... 109 
`Claim 15: “The method according to claim 11, further
`comprising controlling the generator to reduce the
`supplied pressure when a breathing pattern indicative of
`a change from an asleep state to an awake state is
`detected.” ................................................................................. 110 
`
`5. 
`
`6. 
`
`7. 
`
`8. 
`
`9. 
`
`
`
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`U.S. Patent No. 9,427,539
`Declaration in Support of Petition for Inter Partes Review
`
`
`10.  Claim 16: “The method according to claim 11, further
`comprising controlling the flow generator to increase the
`supplied pressure when a breathing pattern indicative of
`a change from an awake state to an asleep state is
`detected.” ................................................................................. 112 
`11.  Claim 18: “The method according to claim 11, further
`comprising analyzing the breathing patterns to determine
`when the patient transitions from an awake state to an
`asleep state.” ........................................................................... 112 
`12.  Claim 22: “The method according to claim 18, further
`comprising increasing pressure provided to the patient
`when a determination of a transition from an awake state
`to an asleep state has occurred.” ............................................ 112 
`13.  Claim 23: “The method according to claim 18, further
`comprising ramping pressure provided to the patient
`when a breathing pattern indicative of a transition from
`an awake state to an asleep state has occurred.” ................... 112 
`XIII.  GROUND 3: SULLIVAN995 ANTICIPATES CLAIMS 1-2, 5-11,
`13, 15-30 ...................................................................................................... 113 
`XIV.  GROUND 4: RAPOPORT502 ANTICIPATES CLAIMS 1-2, 5-11,
`13, 15-30 ...................................................................................................... 114 
`XV.  SECONDARY CONSIDERATIONS ......................................................... 115 
`XVI.  CONCLUSION ............................................................................................ 116 
`
`
`
`
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`U.S. Patent No. 9,427,539
`Petition for Inter Partes Review
`
`
`INTRODUCTION
`I, Khosrow Behbehani, Ph.D., have been retained by Allen & Overy
`1.
`
`I.
`
`LLP on behalf of ResMed, Inc. (“ResMed”) to provide an analysis of the scope and
`
`content of U.S. Patent No. 9,427,539 (“the ’539 patent”) relative to the state of the
`
`art at the time of the earliest application to which the ’539 patent claims priority.
`
`My analysis relates to claims 1-2, 5-11, 13, 15-30. I have also been retained to
`
`provide analysis regarding what a person of ordinary skill in the art would have
`
`understood at the time of the earliest application underlying the ’539 patent.
`
`2.
`
`This report summarizes the opinions I have formed to date. I reserve
`
`the right to modify my opinions, if necessary, based on further review and analysis
`
`of information that I receive subsequent to the filing of this report, including in
`
`response to positions taken by New York University (“NYU”) or its experts that I
`
`have not yet seen, including any secondary considerations evidence that NYU or
`
`its expert may consider and present.
`
`II. EXPERIENCE AND QUALIFICATIONS
`3. My curriculum vitae (“CV”) is Exhibit 1004. I am a Professor in the
`
`Bioengineering Department at the University of Texas at Arlington, specializing in
`
`the design of sleep apnea therapy equipment, the design of CPAP systems for flow
`
`delivery, and biosignal process algorithms.
`
`
`
`1
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`ResMed Inc. Exhibit 1003
`Page 13 of 132
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`U.S. Patent No. 9,427,539
`Petition for Inter Partes Review
`
`In 1973, I was awarded a Bachelor of Science in Mechanical
`
`4.
`
`Engineering from the Louisiana State University.
`
`5.
`
`In 1975, I was awarded a Master of Science in Systems Engineering
`
`from the Georgia Institute of Technology.
`
`6.
`
`In 1979, I was awarded a Ph.D. from the University of Toledo. My
`
`Dissertation was entitled “Sensor Failure Analysis and Multivariable Control for
`
`Airbreathing Propulsion Systems.” My research was conducted for NASA and
`
`onsite at NASA John Glen Center.
`
`7.
`
`In 1985, I joined the University Texas at Arlington as an Associate
`
`Professor (without tenure) in the Biomedical Engineering Program. In 1989, I was
`
`appointed as an Associate Professor (with tenure) in the Biomedical Engineering
`
`Program. I was subsequently appointed as a
`
`tenured Professor
`
`in
`
`the
`
`Bioengineering Department in 1998. From 2001 to 2002, I was the Interim
`
`Director, of the Biomedical Engineering Program. From 2002 to 2013, I was the
`
`Chair of the Department of Bioengineering. From 2013 to 2016, I was the Dean of
`
`the College of Engineering. I currently hold the title of Professor.
`
`8.
`
`I have over 40 years of experience in the research and design of
`
`systems used for the improvement sleep related disorders.
`
`
`
`2
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`ResMed Inc. Exhibit 1003
`Page 14 of 132
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`U.S. Patent No. 9,427,539
`Petition for Inter Partes Review
`
`I am one of the named inventors on nine (9) patents on one of the first
`
`9.
`
`at-home automated CPAP machines. These patents are:
`
`(a)
`
`“Processing and Analyzing Physiological Signals to Detect a
`
`Health Condition,” U.S. Patent No. 7,966,061 B2, Inventors:
`
`M. A. Al-Abed, K. Behbehani, M.T. Manry; Issued: June 21,
`
`2011;
`
`(b)
`
`“System, Software, and Method for Detection of Sleep-
`
`Disordered Breathing Using an Electrocardiogram,” U.S. Patent
`
`No. 7,801,593 B2 Inventors: K. Behbehani, S. Vijendra, J.R.
`
`Burk, and E.A. Lucas; Issued: September 21, 2010;
`
`(c)
`
`“System, Software, and Method for Detection of Sleep-
`
`Disordered Breathing Using an Electrocardiogram,” U.S. Patent
`
`No. 7,343,198 B2 Inventors: K. Behbehani, S. Vijendra, J.R.
`
`Burk, and E.A. Lucas; Issued: March 11, 2008;
`
`(d)
`
`“ECG Derived Respiratory Rhythms for Improved Diagnosis of
`
`Sleep Apnea,” U.S. Patent No. 6,415,174 B1, Inventors: K.
`
`Behbehani, J.R. Burk, and E.A. Lucas; Issued: July 2, 2002;
`
`(e)
`
`“Method and Apparatus for Detection and Diagnosis of Airway
`
`Obstruction Degree,” U.S. Patent No. 6,142,952, Inventors: K.
`
`
`
`3
`
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`U.S. Patent No. 9,427,539
`Petition for Inter Partes Review
`
`Behbehani, J.R. Burk, E.A. Lucas and F.C. Yen; Issued:
`
`November 7, 2000;
`
`(f)
`
`“Methods and Apparatus for Controlling Sleep Disorder
`
`Breathing,” U.S. Patent No. 6,085,747, Inventors: J.R. Axe, K.
`
`Behbehani, J.R. Burk, E.A. Lucas, and F. Yen; Issued: July 11,
`
`2000;
`
`(g)
`
`“Method and Apparatus for Treatment of Sleep Disorder
`
`Breathing Employing Artificial Neural Network,” U.S. Patent
`
`No. 5,953,713, Inventors: K. Behbehani, J.R. Burk, F.J. Lopez,
`
`and E.A. Lucas; Issued: September 14, 1999;
`
`(h)
`
`“Methods and Apparatus for Controlling Sleep Disorder
`
`Breathing,” U.S. Patent No. 5,458,137 (international patents for
`
`this invention have also been issued); Inventors: J.R. Axe, K.
`
`Behbehani, J.R. Burk, E.A. Lucas, and F. Yen; Issued: Oct. 17,
`
`1995; and
`
`(i)
`
`“Methods and Apparatus for Controlling Sleep Disorder
`
`Breathing,” U.S. Patent No.5,203,343 (international patents for
`
`this invention have also been issued); Inventors: J.R. Axe, K.
`
`Behbehani, J.R. Burk, E.A. Lucas, and F. Yen; Issued: April 20,
`
`1993.
`
`
`
`4
`
`ResMed Inc. Exhibit 1003
`Page 16 of 132
`
`

`

`U.S. Patent No. 9,427,539
`Petition for Inter Partes Review
`
`10. Throughout my career, I have published the results of many research
`
`projects that have the investigation into and design of systems to identify and aid in
`
`the amelioration of sleep disorders, including but not limited to apnea.
`
`11. At the University of Texas, Arlington, I currently teach a two-course
`
`series on design of bioengineering equipment, a graduate course on signal
`
`processing of biological signals. In addition, periodically, I teach a graduate course
`
`on design of control systems titled Process Control in Biotechnology. In the past, I
`
`have taught courses on Control System Design, Digital Control of Biomedical
`
`Systems, and Modeling and Control of Biological Systems.
`
`12.
`
`I am member of a number of educational and research organizations,
`
`including:
`
`(a) Charter Fellow, the National Academy of Inventors;
`
`(b)
`
`(c)
`
`Fellow, the Institute of Electrical and Electronics Engineers;
`
`Fellow, American Institute for Medical and Biological
`
`Engineers (AIMBE);
`
`(d) Life Member of Phi Kappa Phi Honor Society;
`
`(e) Member of Tau Beta Phi, the Engineering Honor Society;
`
`(f) Member of Sigma Xi, The Scientific Research Honor Society;
`
`and
`
`(g) Member of Biomedical Engineering Society.
`
`
`
`5
`
`ResMed Inc. Exhibit 1003
`Page 17 of 132
`
`

`

`U.S. Patent No. 9,427,539
`Petition for Inter Partes Review
`
`I have received the University of Texas Chancellor’s Entrepreneurship
`
`13.
`
`and Innovation Award in part for my work on development of sleep apnea
`
`treatment devices.
`
`14.
`
`I am also a recipient of the Professor of the Year Award by Sunrise
`
`Rotary Club of Arlington Texas.
`
`15.
`
`In 2011, I co-organized the Southern Biomedical Engineering
`
`Conference and served as co-chair of the conference.
`
`16. For the past 36 years, I have regularly attended conferences relating to
`
`sleep disorders and chaired such sessions during the conferences. Also, I regularly
`
`read journals that cover research in the field of engineering.
`
`17. A detailed list of my other professional activities, members