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`LUMIFY® Clinical Information
`
`Back to ~
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`for Consume, s
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`FREQUENTLY ASKED QUESTIONS
`
`+ Woa o triol conducted between LUMIFY ond currently ovoiloble
`OTC redneaa reliever eye dropa?
`
`+ Whot % of benzolkonium chloride (BAK) preaervotive ia in
`LUMIFY?
`
`+ Were there ony incidencea of ollergic reoction to low doae
`brimonidine tortrote?
`
`+ Whot typea of potienta/cpecioltiea would LUMIFY be good for?
`
`+ How will LUMIFY offect pupil dilotion?
`
`+ Whot ia the difference between LUM I FY ond current OTC redneaa
`relievera?
`
`+ Con LUM I FY be uaed to counteroct rebound redneaa from other
`gloucomo treotmenta?
`
`+ Woa there on introoculor preaaure (IOP) lowering effect?
`
`+ Doea LUM I FY couae rebound redneaa ond tochyphyloxia aimilor to
`other OTC redneaa relievera?
`
`+ How long doea LUMIFY loat?
`
`+ How quickly doea LUM I FY work?
`
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`LUM I FY® Clinical Information
`
`Back to ~
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`fo r Consume, s
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`L LJ MlF Y
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`<O~CN U S nUI\U t 'n o~o, s
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`+ How did LUM I FY obtein FDA epprovel?
`
`LUMIFY is so effective at reducing redness, your patients can see the difference almost immediately.*
`
`FAST ACTING AND LONG LASTING EFFICACY1
`
`Reported significant
`improvement
`in just one minutet
`
`Maintained significant
`redness reduction
`at eight hou,.t
`
`•
`•
`
`-simulation to reflect average clinical trial results.
`teased on patient reported findings from Phase 3.
`
`Representative of mean
`pre-instillation score: 1.8
`
`Representative of mean
`5 minute post-instillation: 0.5
`
`LOW RISK FOR TACHYPHYLAXIS OR REBOUND HYPEREMIA 1
`
`~ Phase Ill efficacy study2:
`
`41
`
`During Treatment
`Consistent efficacy showed no
`evidence of tachyp hylaxis
`
`~H t l ll 'Ht Ht
`
`Post Treatment
`Return to baseline showed no
`evidence of rebo und hyperemia
`
`Treatment Group:
`I Placebo
`I Low Dose Brimonid ine
`
`Days
`
`p<0.0001·
`
`Overall, cix clinicel studies were conducted in over 600 patients to evaluate safety and efficacy,
`with no evidence of ellergic reection• reported.
`
`1 McL.-urin E Cavet ME GomH PJ Ciolini JB. Brimonidin e o p hthalmic solution 0 .025% for reduction of oculu t•dnHs. Optom Vis Sci. 2018 in preu On•
`teport•d UH o f t • bound hyperem a in Pha u
`Ill Safety Study_ 2Pha u Ill was a double •blind•d ra ndomized p lac•bo contro lled study. n•60.
`
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`2/4
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`Eye Therapies Exhibit 2110, 2 of 4
`Slayback v. Eye Therapies - IPR2022-00142
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`7/12/22, 8 57 PM
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`LUMIFY® Clinical Information
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`Back to ~
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`for Consume, s
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`LUM I FY is the only OTC
`redness reliever t hat primarily
`constricts the venule.
`
`WATCH THE VIDEO >
`
`DRUG FACTS
`
`Direc:tiona
`
`Adulte end children 5 yeere of age end over:
`
`• instill 1 drop in the affected eye(s) every 6-8 hours
`• do not use more than 4 times daily
`• remove contact lenses before use
`• wait at least 10 minutes before re-inserting contact
`lenses after use
`• if using other ophthalmic products while using this
`product, wait at least 5 minutes between each
`product
`• to avoid contamination, do not toud, tip of
`container to any surface
`• replace cap after each use
`
`Children under 5 yeere of age: consult a doctor
`
`See full Drug Facts
`
`Join our professional mailing list
`
`SUBSCRIBE
`
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`Eye Therapies Exhibit 2110, 3 of 4
`Slayback v. Eye Therapies - IPR2022-00142
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`7/12/22, 8 57 PM
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`LUMIFY® Clinical Information
`
`Back to ~
`
`for Consume, s
`
`L LJ MlF Y
`
`<O~C N US nUI\U t'n o~o, s
`
`~ '/JW. Ii"
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`https://www.lumifydrops.com/professional/clinical-information
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