`Millions
`
`$6,000
`
`$5,000
`
`$4,000
`
`$3,000
`
`$2,000
`
`$1,000
`
`$0 k ====t~~E = ~ = ==:::!:===~~= =+--~------ ------- -...,__ _ __;~ ~ __.::::::..____,-----'-;'
`
`2005
`
`2006
`
`2007
`
`2008
`
`2009
`
`2010
`
`2011
`
`2012
`
`2013
`
`2014
`
`2015
`
`2016
`
`2017
`
`2018
`
`..--.-. Basaglar KwikPen
`..--.-. Levemir Pens
`..--.-. Tresiba FlexTouch
`
`..--.-. Lanius 0pliClik
`..--.-. Toujeo Max SoloSTAR
`
`..--.-. Lanius SoloSTAR
`..--.-. Toujeo SoloSTAR
`
`Source: IMS Health
`Note: The long-acting category includes drugs listed under the IMS USC5 codes 39123 (Human Insulins Long Acting), 39133 (Analogs of Human Insulin Long Acting), and 39135
`(Analogs of Human Insulin Ultra Long Acting). Lantus OptiClik is defined as records with Product Summary "LANTUS" and Form TLC3 "FCC DISP SYR REGULAR SC.OL Y." Levemir
`Pens include Levemir FlexPen and Levemir FlexTouch. Products are designated as "Levemir FlexPen" if IMS Health data indicates that Product Summary is "LEVEMIR FLEXPEN" or if
`both Product Summary is "LEVEMIR" and TLC3 code is "GCC DISP SYR LG ACT SC ONLY." Toujeo Max SoloSTAR was first introduced in April 2018.
`
`Sanofi Exhibit 2196.001
`Mylan v. Sanofi
`IPR2018-01676
`
`