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`|||
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`2
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`Project No.___
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`From Page No.—
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`lfbj-test
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`0.35
`77
`70 PHE
`ALA
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`71 m 73
`sea
`0.44
`72 L30
`79
`LEU
`0.64
`73 THR
`80
`ALA
`0.21
`74 ILE 81
`ILE
`0.21
`75 sea
`82
`SER
`0.72
`76 SBR
`83
`GLY
`0.73
`77 VAL
`84
`LBU
`0.74
`78 GLN
`85
`GLU
`0.80
`79 ALA
`86
`ALA
`0.50
`80 GLU
`87
`GLU
`0.85
`81 ASP
`88
`A52
`1.15
`82 LEU
`89
`GLU
`0.70
`83 ALA
`90
`SER
`0.37
`04 VAL
`91
`ASP
`0.33
`NR 05 TYR
`92
`0.2a
`TYR
`86 mm 93
`0.37
`CYS
`87 CYS
`94
`0.80
`ALA
`88 GLN
`95
`1.43
`SER
`e9 ASN
`96
`1.73
`TRP
`90 HIS
`98
`1.26
`sax
`96 TYR 100
`2.29
`SER
`96 PRO 101
`1.35
`TYR
`97 LEU 102
`1.51
`VAL
`98 THR 103
`0.82
`PHE
`99 PHE 104
`1.38
`GLY 100 GLY 105
`THR 101 GLY 105 2-4'
`THR 101 ALA 106
`1-56
`GLY 102 GLY 107
`0.01
`THR 103 THR 108 0-‘6
`LYS 104 LYS 109
`0.59
`VAL 105 LEU 110
`0.74
`THR 106 GLU 111
`0.92
`V'AL 107 In 112 1.36
`mg 12'E¥§~1L_3"1.1.3.2...
`
`Fm- PDE £11": MIN-tut
`Maximum distance cutoff for CA—CA was
`NUMRES molecules 16.2
`112
`118
`1fb4
`2MP
`Res
`Res Dist
`GLU
`1 Asp
`1
`2.31
`VAL
`3 VAL
`3
`2.46
`L20
`4 MET
`4
`0.30
`T1112
`5 THR
`S
`0.62
`GLN
`6 GLN
`6
`0.74
`PRO
`7 SEE
`7
`1.60
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`7 PRO
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`9 SER
`10
`1.08
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`11
`1.91
`sea
`11 51:6
`12
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`GLY
`12 VAL
`13
`1.83
`THR
`13 SER
`14
`1.68
`PRO
`14 ALA
`15
`1.05
`GLY
`15 GLY
`16
`1.06
`GLN
`16 GLU
`17
`1.12
`ARC
`17 ARG
`18
`0.91
`VAL
`10 VAL
`19
`0.40
`'I‘HR
`19 THR
`20
`0.47
`ILE
`20 MET
`21
`0.40
`SER
`21 SER
`22
`0.18
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`22 (:75
`23
`0.33
`THR
`23 LYS
`24
`1.21
`GLY
`24 SEE
`25
`0.84
`THR
`25 SER
`26
`2.16
`THR
`25 GLN
`27
`2.49
`GLY
`28 SER
`28
`1.67
`THR
`31 ASN
`37
`2.18
`THR
`31 pm:
`38
`2.28
`VAL
`32 LEU
`39
`1.41
`ASH
`33 ALA
`40
`0.73
`mp
`34 mp 41
`0.37
`TYR
`35 TYR
`42
`o_3o
`gm 35 cm 43
`0,35
`cm 37 GLN
`44
`0.31
`m 43 p30
`49
`0.55
`PRO
`43 PRO
`50
`0-33
`LYS
`44 LYS
`51
`0.24
`1.1211
`45 LEU
`52
`0.40
`LEU
`46 LBU
`53
`0.76
`ILE
`47 ILE
`54
`0.56
`TYR
`48 TYR
`55
`0.67
`ARG
`49 CL!
`56
`0.79
`ASP
`50 ALA
`57
`0.67
`ALA
`51 51:2
`58
`0.57
`NET
`52 THR
`59
`0.59
`ARC
`53 ARG
`60
`1.25
`PRO
`54 GLU
`61
`1.43
`SER
`55 SEER
`62
`1.37
`out
`56 GLY
`63
`1.01
`VAL
`57 VAL
`5‘
`0-25
`no 53 pao
`65
`0.19
`MR 59 A52
`66
`0.24
`ARG
`60 ARG
`67
`0.48
`PHE
`61 pm:
`68
`0.22
`SER
`62 THR
`69
`0.28
`GLY
`63 GLY
`70
`0.51
`SER
`64 SEE
`71
`0.49
`”(R 68 THR
`75
`1.01
`LYS
`65 CL!
`72
`1.14
`sea
`69 ASP
`76
`0.65
`
`0-33
`6‘
`‘4 533
`33‘
`65 0.90
`65 cm!
`LYS
`66
`2.13
`65 SER
`SER
`53
`o_35
`“R 63 mg
`69 0.96
`BER
`59 SER
`70 0.31
`ALA
`70 TYR
`71 0.45
`SIR 71 SER
`72
`0.25
`1.2-0
`72 LEU
`73
`0.45
`ALA
`73 THR
`74 0.7.
`ILE 74 ILE
`75
`1.03
`SIR 75 ASN
`76
`0.52
`GLY
`76 THR
`77
`0.59
`LEU
`77 MET
`7a
`0.75
`61.0
`78 GLU
`79 0.95
`ALA
`79 ALA
`80 0.61
`GLU
`so GLU
`01
`1.24
`up 81 ASP
`82
`GLU
`82 ALA
`1.40
`35R 03 Am 83
`0.35
`up 34 ILE 84
`0.16
`HR 85 TYR
`85
`0.23
`1111
`86 mm 35
`0,54
`as 67 C115
`37
`0.56
`ALA
`88 GLN
`88 0.4a
`3:51
`89 GLN
`39
`0.53
`HP 90 TR?
`90
`1.58
`ASN
`95 PRO
`93
`2.10
`52R
`96 LEU
`94
`1.57
`TYR
`97 ILE 95
`0.62
`VAL
`98 mm 96
`0.70
`nus
`99 PHE
`97
`0.64
`@Y 100 GLY
`98
`0.77
`run 101 ALA
`99
`1.1a
`Gm! 102 GLY 100
`0.67
`”R 103 THR 101
`0.23
`L‘l'S 104 LYS 102
`0.36
`VAL 105 LEU 103
`0.67
`“R 106 GLU 104
`1~08
`VAL 107 Ill! 105
`0.65
`LI] 100 us 106
`0.65
`114109 m 107
`2.30
`_
`
`.
`
`--
`
`‘
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`.
`
`-
`
`rron PDB files: 1fbd.test
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 1:2
`112
`111
`1fb4
`lfbj
`Res
`Res Dist
`010'?
`1 GLU
`1
`1.53
`LEU‘I
`4 L80
`4
`1.2)
`THR?
`5 THR
`5
`0.93
`GLN
`6 GLN
`6
`0.57
`PRO
`7 SER
`7
`1.20
`PRO
`7 PRO
`8 23‘
`PRO
`8 AI}.
`9
`0.68
`SER
`9 ILE
`10
`1.37
`ALA
`10 THR
`11
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`SER
`11 ALA
`12
`1‘43
`GLY
`12 ALA
`13
`0.88
`THR
`13 SEE
`l4
`0_4‘
`PRO
`1, LEU
`15
`0.52
`GLY
`15 GLY
`16
`0.17
`GLN
`16 cm 17
`0.30
`ARG. 17 us 18
`0.25
`VAL
`18 VAL
`19
`0.68
`,HR 19 THR
`20
`0.85
`“18,, 20 ILE
`21
`0.12
`saair 21 THR
`22 o.“
`CYSIJ 22 CYS
`23
`0 28
`THE} 23 SR 24
`0‘99
`cm 24 m 25
`0:37
`”R 25 52.2
`26
`1.95
`”R 25 SER
`27
`2.33
`SER
`26 SER
`27
`1.77
`BER
`27 SER
`28
`2.44
`ILE
`30 55R 30
`1,00
`THR
`31 SE‘R
`31
`1,47
`VAL
`32 L30
`32
`1.00
`ASN
`33 H15
`33
`0.26
`m 34 TRP
`34
`0.47
`TYR
`35 NR 35
`0.53
`GLN
`36 cm 36
`0.3a .
`GLN
`37 GLN
`37
`0.41
`LEU
`3g LYS
`38
`2‘15
`LEU
`38 SER
`39
`2_13
`MET
`41 THR
`41
`2.21
`ALA ‘42 SER
`42
`0.50
`PRO: 43 pm)
`43
`0.96
`ms? 44 LYS
`44
`0.63
`mu 45 PRO
`45
`0.83
`W ,6 mp
`46
`0.75
`IL!)
`47 IL}:
`47
`0.14
`TYR
`48 'I'YR
`48
`0‘51
`ARG
`.9 cm 49
`1.61
`5p 50 ILE
`50
`1 22
`ALA
`51 SER
`51
`0:40
`KIT
`52 LYS
`52 0'74
`ARC
`53 LEU 53
`1 02
`no 54 M 54
`2‘21
`no 54 SER
`55
`2:33
`an 55 SER
`55
`2 19
`cm 56 cm 56 126
`“L 5-, VAL
`57
`1:16
`no 58 PRO
`58
`0_92
`run
`59 ALA
`59
`0'52
`m 60 ARC
`60
`0.59
`m 61 PHE
`61
`0.56
`m ' g
`‘
`_
`CL!
`‘3 2:
`‘3 3.3
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`.
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`add/L7 H2470! WM...
`
`Id
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`.2
`
`To Page No.3.—
`
`Witnessed l Understood by me.
`
`Date
`
`Invented by
`
`Date
`
`-.
`
`Page 14 of 68
`
`
`Rocordvod by
`
`Page 14 of 68
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`

`

`
`
`“115
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`Project No.
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`Book No._.__
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`73 THR
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`75 SER
`76
`76 SER
`77
`77 LEU 78
`78 cm 79
`79 PRO
`80
`80 CL”
`81
`81 “SP
`32
`82 ILE
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`83 ALA
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`84 THR
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`85 TYR
`86
`86 TYR
`87
`87 cars
`88
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`89
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`90
`90 TV“
`91
`95 LE”
`94
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`95
`97 "R g?
`33 3:;
`96
`99
`10° 6”
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`102 GLY 101
`103 THR 102
`104 LYS 103
`.58
`105 LBU 104
`.63
`106 GLN 105
`34
`‘73
`107 ILE 106
`1.
`191 111111.191 215i:
`
`From PDB files: 1FBQ.TEST
`Maximum distance cutoff for CA~CA was
`NUMRES molecules 162
`112
`107
`“‘84
`lREI
`Res
`Res Dist
`Asp
`.28
`cw
`MET
`.81
`no
`m THR
`.43
`CL!
`cm
`_53
`SER
`.84
`PRO
`.13
`S'ER
`.65
`51.33
`.45
`mu
`,0:
`AIA
`.84
`553
`.54
`VAL
`.09
`GLY
`.83
`ASP
`.11
`ARG
`.52
`VAL
`42
`THR
`‘4,
`ILE
`I“
`THR
`‘2.
`Cys
`.35
`cm
`.75
`ALA
`.58
`SER
`.64
`GLN
`.25
`A59
`.27
`ASP
`.82
`TYR
`.41
`LEU
`.93
`ASN
`.61
`TRP
`.29
`TYR
`.23
`GLN
`'13
`.
`GLN
`“
`ALA
`7-,
`PRO
`3.
`LYS
`.42
`LEU
`.23
`LE”
`.59
`ILE
`.56
`TYR
`.55
`cm
`'05
`Am
`_"
`SER
`‘ .1
`As"
`n
`mu
`.05
`Gm
`.31
`m
`.43
`GLY
`.61
`VAL
`.44
`PRO
`.60
`SER
`.45
`ARG
`.36
`PHE
`.22
`SER
`10
`GLY
`_25
`SER
`.40
`GLY
`.41
`GLY
`’3‘
`THR
`.10
`.w
`ASP
`. 52
`TYR
`- ._
`
`EEEiEEE
`5533
`
`—--
`
`.
`
`Witnesaod 8: Understood by me,
`
`Invented by
`
`Page 15 of 68
`
`Recorded by
`
`Iran PDB files: 1FB4.'X'EST
`Maximum distance cutoff for CA-CA was
`MES molecules 1&2
`112
`107
`111134
`11231
`Res
`Res Dist
`ASP
`2.46
`0
`MET
`.65
`THR
`.57
`GLN
`.56
`SER
`.73
`PRO
`.24
`SER
`.70
`SER
`.42
`LEU
`.40
`SER
`.33
`ALA
`.67
`SER
`.16
`VAL
`.41
`GLY
`.43
`AS?
`.03
`ARG
`.62
`VAL
`.45
`THR
`.66
`ILE
`.43
`THR
`.36
`cars
`.34
`GLN
`.75
`ALA
`.69
`SER
`.29
`GLN
`.19
`GLN
`.34
`ASP
`.04
`ASP
`.09 .
`TY
`.26
`LE”
`-'9
`ASN
`.66
`TR?
`.22
`TYR
`0.25
`GLN
`.34
`GLN
`.55
`THR
`.29
`ALA
`.76
`PRO
`.3!
`LYS
`.35
`LEU
`.40
`LEU
`.61
`ILE
`. 43
`TYR
`.44
`GLU
`.04
`ALA
`.78
`SER
`.60
`A5”
`-53
`LEU
`.se
`GLN
`.13
`ALA
`.64
`GLY
`.as
`VAL
`.37
`PRO
`.26
`51:11
`.29
`ARG
`.17
`PHE
`.09
`SER
`.12
`GLY
`.18
`SEE
`.36
`GLY
`. 46
`GLY
`. 27
`"M
`
`0012Ol22l2l0l0O0O00O022222lO0 o
`
`O0200000O010O0O1lO00O0O0O002
`
`GLU
`L30
`THE
`613
`mo
`PRO
`PRO
`st:
`ALA
`sea
`CL!
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`mC
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`ELI
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`IL).
`'10
`LIB
`LII
`L!!!
`E
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`iifiiiéfifiéfiififififi
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`El1-H
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`'E53
`
`
`OOONOOOOOOOOOOP—‘I—‘HOOOHOOOOOOOOOOOOOHHNNP—‘OOOOOOOOHOHD—‘HNHONHOOOU
`
`Page 15 of 68
`
`

`

`4
`
`I
`
`Project No.
`Book No.______
`
`TITLE
`
`
`
`ran Page No... -
`
`u
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`-
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`2.50
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`2'50
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`
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`
`Fro. PDB files: 1fbl.tcst
`Maximum distance cutoff for CA~CA was
`mas molecules 14.2
`112
`114
`lfb4
`2m:
`Res
`Res Dist
`VAL
`3 VAL
`3
`1.05
`0.24
`64
`5:8 42 st:
`~ mu
`4 LE”
`4
`0-37
`0.66
`GLY
`63 Am 65
`m 5 THE
`5
`0‘37
`0.34
`SER
`64 SER
`66
`- CL"
`5 CL"
`6 0-1‘
`0.16
`LYS
`65 LYS
`67
`"0 7 PRO
`7 0'“
`0.36
`SER
`66 SEE
`68
`"‘3
`8 FRO
`3
`0‘29
`0.19
`GLY
`67 GLY
`69
`39“
`9 55“
`9
`(7-79
`0.19
`THR
`68 THR
`70
`A” 10 ALA
`1° 0'“
`0.25
`BER
`69 SER
`71
`5'“ 11 SE“
`11 0'”
`o 14
`61.1!
`12 GLY
`12
`0.36 m 70 ALA
`72
`0.33
`m 13 TH“
`13 0'”
`SER
`71 SER
`73
`0.26
`"‘0 1‘ PRO
`14
`0'74
`LEU
`72 LEU
`74
`0.21
`G”
`15 G” 15
`0-5‘
`ALA
`73 ALA
`75
`cm 16 GLN
`16
`0.34
`mg
`74 ILE 76 0.2,
`“G 17 “RS
`17
`0'50
`SER
`75 SEE
`77
`0.51
`VAL
`18 VAL
`18
`0-53
`GLY
`76 GLY
`78
`1.01
`m 19 THR
`19 0-5‘
`LEU
`77 LEU 79
`0.65
`IE 20 1”?
`2°
`0-07
`GL0
`78 GLU
`80
`0.46
`g“;
`33% (535R 5; 8-3:
`ALA
`79 SER
`81
`0.41
`Tm 23 TH:
`23
`0'34
`GLU
`80 GLU
`82
`0.54
`24 G y
`24
`0-22
`A59
`81 A39
`83
`0.45
`9“
`L
`-
`GLU
`82 GLU
`84
`0.32
`m 25 53“
`25
`0-37
`SER
`B3 ALA
`85
`0.25
`gm 3: :3:
`g?
`3-2?
`ASP
`84 ASP
`86
`0.23
`A3; ”MS?
`28 0'3.
`TYR
`85 TYR
`87
`0.27
`11.9
`2781”:
`29 0'29
`TYR
`86 TYR
`88
`0.28
`-
`075
`87 cys
`89
`0.33
`CH!
`28 GLY
`30
`0.40 m 88 Am 90
`0.36
`x i3 :3 g;
`845’;
`SER
`89 ALA
`91
`0.20
`m 31 SER
`33
`0'76
`TR?
`90 TR?
`92
`0.33
`VAL
`32 VAL
`34 0'”
`A58
`91 A58
`93
`0.80
`m 33 I”:
`35 0'”
`68A 92 ASP
`94
`1.37
`1139
`34 TR?
`36
`0'10
`A99
`94 SER
`95
`1.86
`-
`Asp
`94 LEU
`96
`2.34
`2112
`35 m 37
`0.44
`38 0.6'
`‘5"
`95 ASP
`97
`0‘76
`and
`36 GLN
`SER
`96 GLU
`98
`1.74
`u 37 GLN
`39
`1.29
`“R 97 PRO
`99
`0 50
`Llu
`38 VAL
`40
`2.15
`VAL
`98 GLY 100
`0'56
`«Ly
`40 PRO
`41
`1.91
`ME 99 Pm: 101 0'93
`m 41 LYS
`43
`2.34
`GM 100 GLY 102
`0‘77
`m 42 “S ‘3 2-”
`HR 101 GLY 103
`0.96
`“14‘
`‘2 ALA ” 1-"
`ELY 102 GLY 104 089
`no 43 PRO
`45
`1.21
`”R 103 THR 105
`0'25
`. LYS
`44 LYS
`46
`0.49
`us 104 LYS 106
`02.3
`1.!)
`45 LEU
`47
`0.77
`VAL 105 LEU 107
`0 20
`LlJ
`46 LEU
`48
`0.37
`”R 106 THR 108 0'25
`' h'
`113:
`47 ILE 49
`0.14
`VAL 107 vAL 109 0'32
`m 48 TYR
`50
`0.07
`-
`LEU 108 LEU 110
`1.45
`At;
`49 TYR
`51
`0.47
`.._
`L.
`_L_._ _,.
`,_ _
`MP
`50 A50
`52
`0.52
`ALA
`51 A59
`53
`0.44
`m 52 LEIU
`54
`0.46
`us 53 LEU
`55
`0.64
`no 54 PRO
`56
`0.79
`m 55 SER
`57
`1.05
`cm 56 GLY
`58
`0.64
`VAL
`57 VAL
`59
`0.50
`rno
`58 SER
`60
`0.33
`nc 60 A30
`63
`0.40
`m 59 ASP
`61
`0.29
`nu 61m 63
`0.11
`.
`.
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`
`-
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`
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`
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`
`“'0'? PDE F1135: 1FB4‘TEST
`mmxum dLStance CUtOff for CA—CA was
`WES molecules 152
`112
`105
`I?!“
`3F”
`.
`Res
`Res Dlst
`SIR
`1 53R
`1-75
`2
`0.97
`74
`74 11.2
`11.8
`:23
`2 figs
`2 3'3:
`0.94
`75 94m 75
`508
`“R 5 THR
`5
`0'26
`1.39
`76 GLY
`76
`GLY
`6 cm 6 0'41
`1.14
`77 LEU 77
`LEU
`61.8
`7 PRO
`7
`0'56
`0.36
`78 GLN
`78
`GLU
`a 0'3‘
`"‘0
`0.43
`79 ALA
`79
`ALA
`PRO
`8 “2
`9 0'5.
`0.69
`80 GLU
`80
`GLU
`“R 13 313“.
`10 0'40
`0.51
`81 A59
`81
`ASP
`“A
`‘
`7
`0 48
`82 61.0
`82
`GLU
`55R 11 SE“
`11 0"
`0.25
`83 ALA
`83
`SER
`G” 12 G”
`12 0'53
`0.39
`84 ASP
`84
`AS?
`"R 13 ALA
`l3 0'8
`0.18
`85 TYR
`85
`I'YR
`PRO
`1" PRO
`14 1'“
`0.18
`TR 86 TYR
`86
`GL‘I
`1g ELY
`12
`1.1g ._
`0.30
`CYS
`87 cuts
`87
`51‘”
`1
`L“
`7 0'”
`0,27
`ALA
`88 GLN
`88
`ARC
`17 ARC
`1
`~71
`‘
`0.64
`SER
`89 SER
`89
`VAL
`1" VAL
`18
`0'
`0.95
`TRP
`90 TYR
`90
`TH“
`19 ”R 19
`0'79
`0.59
`$5:
`3(1) 315:
`32
`8‘13 ._ ASN
`91 ASP
`91
`1.93
`073
`22 cats
`22
`0'20
`SER
`92 ARG
`92
`0,94
`“R 23 THR
`23 0'"
`sea
`95 L120
`94
`0.28
`'
`TYR
`97 AAG
`95
`0 71
`a“ 2‘ G”
`g; 8'50
`VAL
`98 VAL
`98
`0.87
`:2:
`32 fig:
`26 0‘3:
`FEB
`99 FEB
`99
`0.25
`ER 27 gm 27 1'”
`GLY 100 GLY 100
`2.24
`ASN 27%“
`27A 0'”
`THR 101 GLY 101
`1.65
`'
`GLY 102 GLY 102
`0 58
`[LE 27BILE
`278 0.61
`THR 103 THR 103
`0.41
`.-
`fig:
`33 ii:
`32C 2:},
`LYS 104 LYS 104
`0.37
`I
`ILE 30 ASN
`30 0:5,
`VAL 105 LEU 105
`0.33
`4__
`HR 31 ms
`31
`0 fl
`THR 106 THR 106
`0.30
`VAL
`32 VAL
`32 0'”
`VAL 107 VAL 107
`0.83
`ASN
`33 LYS
`33 0'“ '
`LE'U 108 LEU 108
`2
`'
`GLY 109 A80 109
`'46
`m 34 m 34
`0.79 1‘
`35 0."
`FELEQELNL 11° 2J§
`178
`35 TYR
`.
`77—-
`l
`0L8
`36 cm 36 0.” 4- - +——
`——L— + 4
`- +
`GLN
`37 cm 37
`0.74 =
`LEU 38 LEU
`38
`1.02 L__._+ _
`821
`41 THR
`41
`1.88
`m ‘2 m ‘2 1'"
`'
`PRO
`‘3 PRO
`‘3 0'” '— '
`LYS
`44 LYS
`44
`0.04 ,
`I
`LEIU
`45 La;
`45 OJ} L.
`,_+_ _
`LEU 46 LEU
`46
`1,04 '
`.
`I
`A80
`53 PHE
`48
`2.01
`THR
`59 ALA
`52
`1.41
`“---J—-L-—— -—w- — -—
`AAG
`60 ARG
`53
`0.20
`‘
`pm:
`61 pm:
`61
`0.17
`,
`
`SER
`62 SER
`62
`0.14 t,
`.
`0.60 1
`GLY
`63 VAL
`63
`_—*" ' 1"“ SER
`64 SER
`64
`0.03 r—‘F-JI—-r-—+- ~*—+——-v— — ~
`'
`LYS
`65 LYS
`65
`0.73
`,
`- —-..—4.— —— _ .
`SER
`66 SE‘R
`66
`0.93
`+~_..+_
`L._ L ,
`GLY
`67 GLY
`67
`0,70
`‘
`.
`THR
`68 SEE
`68
`0.59
`SER
`69 SER
`69
`0.47 f
`ALA
`70 ALA
`70
`0.22 ‘
`LEU 72 L80
`72
`0.57
`+
`SER
`71 THR
`71
`0.35
`_ ALA
`73ALA 73
`0.36 ___4_
`
`— -
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`..
`To Page No. 5:.
`
`'
`
`L
`
`“
`
`'
`
`'
`
`__
`'
`
`Witnnuod l Underotood by me.
`
`Date
`
`Date
`
`Page 16 of 68
`
`
`Rocordod by
`
`Page 16 of 68
`
`

`

`TITLE
`
`From Plfii Nu.
`
`Project No.
`Book No.
`
`
`
`
`
`2hfl.telt
`2 . 50
`
`‘HOHHOOOOOOOOCONNMOOOOOOOOOOOOOOOOOOO
`
`1
`
`SER
`LEU
`ALA
`ILE
`SER
`GLY
`LEU
`GLU
`ALA
`GLU
`ASP
`GLU
`SER
`ASP
`TYR
`TYR
`cys
`ALA
`SER
`TRP
`TR?
`ASH
`SER
`TYR
`VAL
`PHE
`GL‘I
`THR
`GLY
`THR
`LYS
`VAL
`'I‘HR
`VAL
`LEU
`GLY
`
`-
`
`lfb4.test
`From PDB files:
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 1&2
`112
`110
`lfhll
`th1
`Res
`Res Dist
`LEU
`. 87
`THR
`. 46
`GLN
`. 46
`SER
`. 09
`PRO
`. 02
`ALA
`. 51
`ILE
`. 75
`MET
`. 16
`SER
`. 79
`ALA
`. 27
`SER
`. 96
`PRO
`. 69
`GLY
`. 38
`GLU
`. 99
`LYS
`. 39
`VAL
`. 50
`THR
`. 65
`MET
`. 32
`THR
`. 4O
`CYS
`. 28
`SER
`. 43
`ALA
`. 37
`SER
`. 91
`SER
`. 31
`SER
`. 89
`TYR
`. 01
`MET
`. 39
`TYR
`. 39
`TRP
`. 4 0
`TYR
`. 58
`GLN
`. 4 3
`GLN
`. 4 3
`LYS
`. 71
`SER
`. 43
`PRO
`, 37
`LYS
`. 46
`ARG
`. 48
`TRP
`. S7
`ILE
`. 39
`TYR
`. 51
`ASP
`. 31
`THR
`. 30
`SER
`. 16
`LYS
`. 28
`LEU
`. 24
`ALA
`. 15
`GLY
`. 19
`VAL
`.04
`PRO
`. 81
`VAL
`. 34
`ARG
`. 42
`PHE
`. 42
`SER
`. 59
`GLY
`. 33
`SER
`. 34
`GLY
`. 11
`SER
`. 08
`GLY
`. 25
`THR
`. 62
`SER
`. 72
`TYR
`. 36
`
`LEU
`THR
`GLN
`PRO
`PRO
`PRO
`SER
`ALA .
`SER
`GLY
`THR
`PRO
`GLY
`GLN
`ARG
`VAL
`THR
`ILE
`SER
`CYS
`THR
`GLY
`THR
`SER
`GLY
`THR
`VAL
`ASN
`TRP ,
`TYR
`GLN
`GLN
`LEU
`ALA
`PRO
`LYS
`LEU
`LEU
`ILE
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`OOOMNHOOOOCOOHHNHOOOOOOOOOOOD—‘OOOOOOHHNHOOOOOOOCOOOOHHNHONNOOO
`
`Page 17 of 68
`
`.1;
`
`__.L.
`
`To Page No.—
`
`Page 17 of 68
`
`

`

`6
`
`Book No._______
`
`TITLE
`
`Project No.
`
`From Page No._
`
`
`
`. .. ....._
`
`
`
`2mcp.test
`2.50
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`7
`
`In. PDI files: lfbj.telt
`minu- distance cutoff for (IA-CA was
`Auuzss molecules 152
`111
`11a
`lfbj
`2mcp
`Res
`Res Dist
`0111'
`1 ASP
`1
`1.57
`”3' 2m 2
`VAL
`3 VAL
`3
`0.84
`1-32
`W 4 MET
`4
`0.51
`'I‘HR
`5 THR
`5
`0.50
`sun
`7 SEER
`7
`°~31
`cm 5 GLN
`5
`0-28
`"0
`3 PRO
`5
`0.50
`ALA
`9 51:8
`9
`0.81
`rm 10 SER
`10
`1.00
`m‘ 11 LEU 11
`1.10
`ALA' 12 SER
`12
`1.35
`A1)“ 13 VAL
`13
`1.71
`m 14 SER
`14
`1-62
`1"“
`15 m 15
`1.13
`an 16 GLY
`15
`1-05
`CU" "17 CL”
`17
`1-15
`”5 '15 ARC
`15
`0.52
`m ‘ 19 VAL
`19
`0-45
`m.‘ 20 THR
`2°
`0.34
`ILE' 21 MET
`21
`0-55
`W 22 SER
`22
`0-32
`crs
`23 CYS
`23
`0.42
`an 24 LYS
`24
`0.60
`ALA
`25 SER
`25
`0-41
`53!
`26 SER
`26
`1‘57
`m 27 CL“
`27
`1-94
`3“ 28 5“ 28
`0.75
`m 29 LEU
`29
`1.43
`9::
`31 pm:
`38
`0.57
`L00
`32 LEU 39
`0.71
`Hrs
`33 ALA
`40
`0.30
`m 34 TRP
`41
`0.38
`In 35 TYR
`42
`0.48
`GD!
`36 GLN
`43
`0.54
`61.44
`37 GLN
`44
`0.66
`us 38 LYS
`45
`2.07
`an 39 PRO
`46
`0.52
`GL1
`40 GLY
`47
`0.74
`m 41 cm 43
`0.36
`an 42 PRO
`49
`0.75
`no 43 PRO 50
`0.77
`L5:
`44 LYS
`51
`0.73
`m 45 LEU 52
`0.67
`m 46 LEU 53
`0.62
`:11 47 ILE
`54
`0.89
`m 48 TYR
`55
`1.57
`cw 49 GLY
`55
`0.95
`11.:
`50 ALA
`57
`0.80
`5- 51 SER
`58
`1.15
`L‘I'B
`52 THR
`59
`1.20
`La;
`53 ARG
`60
`1.34
`ALA
`54 GL0
`61
`1.89
`$6:
`55 SER
`52
`1.17
`CL!
`56 GLY
`63
`1.01
`VAL
`57 VAL
`64
`1.00
`no 58 PRO
`65
`0.50
`ALA
`59 ASP
`65
`0.64
`An:
`60 ARG
`67
`0.56
`m 61 PHE
`68
`an 62 was
`69 0.11
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`70
`63 GLY
`GLY
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`71
`64 SER
`SER
`0 5.
`Gm 55 Gm 72
`’
`0'87
`51m 66 SEER
`73
`0.54
`CL)!
`67 GLY
`74
`0.32
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`68 THR
`75
`0.55
`gm 59 AS?
`75
`0_15
`TYR
`70 PHE
`77
`0_15
`SER
`71 THR
`7s
`0.22
`1.8-0
`72 LEU
`79
`NR 73 THR
`80 o.“
`ILE 7, RE 81
`0.75
`ASN
`75 SEE
`82
`1.01
`THR
`75 5m 33 031
`MET
`77 VAL
`84
`1.36
`GLU
`78 GLN
`85
`1.3a
`ALA
`79 ALA
`86
`1_33
`GL0
`80 GL0
`87
`1.33
`ASP
`81 A5,,
`88
`0.70
`ALA
`82 LEU
`89
`1.87
`ALA
`83 ALA
`90
`0.52
`ILE
`84 VAL
`91 03‘
`Tm 85 NR 92 0.3.
`TYR
`86 TYR
`93
`0.34
`0‘15
`87 CYS
`94
`0.22
`GLN
`88 GLN
`95
`0.40
`Gm 89 ASN
`95
`1.12
`TR?
`90 Asp
`97
`1.75
`TR?
`90 HIS
`98
`2.05
`THR
`91 HIS
`98
`1 90
`LEU
`94 ”R 100 1'”
`ILE
`95 L30 102 1'“
`MR 95 THR 103 1'“
`PHE
`97 PHE 104 1'1,
`GLY
`90 Gm 105 1'” .
`ALA
`99 m 106
`1:55
`G“ 100 Gm, 107 0‘"
`THR 101 THE 108 0.7]
`ms 102 ms 109
`0774
`m 103 LEU 110
`1.90
`GL0 104 cm 111 OJO
`m 105 ILE 112
`1.32
`LYS 106 LYS 113 1.3,
`ARG 107 MG 114
`1.20
`- "7 "Tar
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`Fm PD” £11“: lfbj.test
`Maximum distance CUtOff for CA—CA was
`“RES molecules 15?
`111
`11"
`1fbj
`2M1
`Res
`Res Dist
`Gm
`1 ASP
`1
`1.34
`m ms
`2
`VAL
`3 VAL
`3
`0.48
`0‘51
`W ‘ LE”
`4
`0.81
`THR
`5 THR
`5
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`53R
`7 SER
`7
`cm 6 CL”
`6 “2°
`PRO
`8 PRO
`8
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`0.19
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`0.8a
`THE
`11 MET
`11
`0.41
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`12 SER
`12
`0.48
`ALA
`13 ALA
`13
`0.65
`am 14 SEE
`14
`0.74
`“U 15 PRO
`15
`1-17
`any
`16 GLY
`15
`0.52
`CL"
`17 GLU
`17
`0‘93
`”5 18 ”S 18
`0'55
`VAL
`19 VAL
`19
`0‘23
`"R 2° THR
`2° 0'25
`11.2
`21 MET
`21
`0.44
`m 22 ”R 22 0‘”
`CYS
`23 CYS
`23 0’”
`SIR 24 SER
`2‘
`0-30
`”A 25 ALA
`25
`0-4°
`”R 26 S“ 26 0'"
`“R 27 5“ 27
`0-95
`“R 28 S“ 28 2'”
`m 29 VAL
`29
`1.20
`" m 31 TYR
`31
`2.06
`LIU 32 MET
`32
`0.74
`us 33 TYR
`33
`0.241
`up 34 TRP
`34
`0.19
`HR 35 TYR
`35
`0144
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`GLN
`36 GLN
`35
`0.00
`GLN
`37 GLN
`37
`0.49
`us 38 LYS
`38
`0.40 ....
`an 39 SER
`39
`1.29
`cm 40 GLY
`40
`0.97
`f“ 41 THR
`41 a” 4
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`42
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`0.03
`,
`us 44 LYS
`44
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`no 45 ARG
`45
`0.50
`up 46 TRP
`45
`0.54
`ILE
`47 ILE 47
`0.29
`HR 48 ”HR
`48
`0.08
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`49 1.4-
`ILE
`50 THR
`50
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`918
`51 SER
`51
`0.33
`LYS
`52 LYS
`52
`0.50
`110
`53 LE!)
`53 0.1:
`ALA
`54 ALA
`54 0.7:
`BER
`55 815R
`55
`0.0-4
`an 55 GLY
`56
`1.23
`VAL
`57 VAL
`57 0.1.
`no 58 PRO
`58
`0.15
`ALA
`59 VAL
`59
`0.74
`us 60 ARG
`60
`0.51
`"a 51 PHE
`51
`0.14
`83R 62 SEE
`62
`0.27
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`22 23;
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`65
`0.27
`55 GLY
`GLY
`66
`o 36
`66 SER
`SER
`7 Gm 67 Gm 67
`0-69
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`THR
`68 THR
`58
`0.34
`5511
`69 53R 69
`0.40
`TyR
`70 Tya
`70
`0.07
`SER
`71 SEE
`71
`0 43
`LEU
`72 LEU 72
`0'37
`THR
`73 THR
`73'
`0'05
`ILE
`74 ILE
`74
`0'20
`As"
`75 SER
`75
`0~25
`THR
`75 SER
`75
`0-19
`m 77 MET
`77
`0'29
`GLU
`78 GLU
`78
`0'26
`ALA
`79 THR
`79
`0:52
`GLU
`80 GLU
`80
`0 47
`ASP
`81 ASP
`81
`0.48
`ALA
`82 ALA
`82 0'78
`m 83 ALA
`83
`0'34
`[LE
`84 GLU
`84
`0'33
`TyR
`85 Tya
`35 0'15
`Tm 86 TYR
`85
`0‘52
`cys
`87 cys
`87
`0‘15
`GLN
`88 GLN
`88
`0.28
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`89 CL"
`39 0'19
`mp
`90 TR?
`90 100
`THR
`91 GM 91
`1‘87
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`TYR
`9? ARC
`92
`2-33
`PRO
`93 ARG
`92
`1-84
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`9‘ AS"
`93
`1~23
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`94
`0453
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`96 THR
`95
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`PHE
`97 ““3
`96
`0-33
`GLY
`98 CW 97
`0~63
`ALA
`99 GLY
`93
`0~73
`G“ 100 G” 99 0-1‘
`{HR 131 THR 100 0.38
`VS 1 2 ”S 101
`0-‘3
`533 133 L3” 102
`0-33
`L
`1 4 6“” 103 0'“
`L3” 105 ILE 10‘
`0-97
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`31353974129- L05
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`Witness“! & Understood by me,
`
`Date
`
`invonlod by
`
`Dag.
`
`To Page No.
`
`Page 18 of 68
`
`
`Recon-lad by
`
`Page 18 of 68
`
`

`

`TITLE
`
`From Page No.
`
`
`
`Project No.
`
`Book No.
`
`7
`
`Fro- PDB files: ltbj.test
`toff for CA-CA was
`$332332: :22 111
`107
`1fbj
`lrei
`Res
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`ASP
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`From PDB files: lfbj.test
`Maximum distance cutoff for CA—CA was
`mas molecules 152
`111
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`Wlmuud t Undwstood by me.
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`
`Page 19 of 68
`Recorded by
`____—___——_________4
`
`To Pogo No.___
`
`Page 19 of 68
`
`

`

`8
`
`From Page No._
`
` Project No._____ - M
`
`Book No.___ TITLE M703? W
`
`i.it-l'."lllIflFill!IllIIIIIiIIl1lllIIIIIIillIlIllIIIIlflllIllllIIllIIIllitIl
`P34L,
`JFAB and RHE are lambda-type REI, HCPL, FBJL AND ZHFL are kappa—type
`fittfltitfifikltfitittkkttfittinifliifitflkfiitflhtittttthtitttk‘fitfifinflflflfikitttfltfiittflifiti
`3) residues between parentheses are included in beta-sheet based on backbone
`dihedral angles and hydrogen-bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`c) L1, L2, L3 correspond to hypervariable loops
`d) @ first residue is PCA - pyroglutamyl
`a) small letter in sequence - Ca—Ca distance between proteins > 1.0 A
`iiiiiil‘lI'l*lliii*l*flili§lirlfllillII'll-[IiiIllilliifiipili+piifiifiiipifipfntn
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`Page 20 of 68
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`Page 20 of 68
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`0’
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`Project No._.__
`TITLE W #2, W W BookNo._.___
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`From Page No...
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`ii'li'lIIIIFflfll'lali'lll'llIIIlIIIIIIiIIII-IIl"-ii‘i‘iF'I'IIf.If.IIll-II:l-vll-IiIl-llll-vl-i-Il-iipqq-piflffl
`FB4L,
`3FAB and RHE are lambda—type
`tittiitttitilitittitik1t*1*rttxittittitflkIItfltiittttrI*ttitilinkfittttfittfitttfil
`a) residues between parentheses are included in beta—sheet based on backbone
`dihedral angles and hydrogen—bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`G) L1, L2, L3 correspond to hypervariable loops
`6) @ first residue is PCA - pyroglutamyl
`e) small letter in sequence - Ca—Ca distance between proteins ) 1.0 A
`ttk**t*ttfiififi***tfitfifititit!tfltkitiiitittflfitttfitflt.fififikfltittfliifififiitttttfi*tffltn
`A'A'A'A'A'A'
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`V S G A p q q R V T I S C T G S
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`ttttttttitikttttt*kflfltxittttii‘flttfifl‘ttitfitflfififiitttitkfifiiktit**flik*i*t*tttittt
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`RBI, MCPL, FBJL AND ZHFL are kappa-type
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`a) residues between parentheses are included in beta-sheet based on backbone
`dihedral angles and hydrogen-bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`c) L1, L2, L3 correspond to hypervariable loops
`d) small letter in sequence - Ca-Ca distance between proteins ) 1.0 A
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`Minna-d l Understood by me.
`
`Page 21 of 68
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`Page 21 of 68
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`From Page No...
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`Project No.
`Book No.___.
`
`TITLE
`
`krd Lungth- a Angles for KAPPA variable light
`N—Ca Ca-C
`C-O C’N Cl—Cb
`C—R'CI N-Ca—C CI—C-O Ca—C-N 0~C~N l—Cl—Cb Cb‘Cn‘
`1.459 1.515 1.208 1.288 1.508
`123.5
`ll0.0 120.5
`116.6
`123.1
`110.3
`111.4
`0.012 0.012 0.062 0.049 0.026
`4.2
`4.0
`1.9
`4.0
`4.1
`2.1
`2.4
`7
`72
`72
`65
`66
`65
`72
`72
`65
`65
`66
`66
`Bon Lengths a Angles for LAMBDA variable light
`N~Ca Ca-C
`C-O C-N Ca-Cb
`C—N-Ca N-Ca-C Ca-C-O Ca~C-N O-C-N N-Ca-Cb Cb-Ca-
`1.453 1.514 1.217 1.298 1.522
`124.4
`111.4
`120.1
`117.0
`122.7
`110.4
`109.9
`0.017 0.018 0.063 0.061 0.031
`6.0
`2.4
`1.9
`4.8
`4.9
`2.7
`2.4
`97
`97
`97
`92
`87
`92
`97
`97
`92
`92
`87
`87
`
`Bond Lengths & Angles for KAPPA 5 LAMBDA variable light
`N-Ca Ca-C
`C-O C-N Ca-Cb
`C—N-Ca N-Ca-C Ca—C-O Ca-C-N O-C—N N~Ca-Cb Cb-Ca-
`1.452 1.510 1.190 1.288 1.510
`124.3
`110.7
`120.6
`117.5
`121.9
`110.4
`110.8
`0.014 0.016 0.129 0.081 0.029
`6.7
`3.1
`2.5
`7.6
`9.6
`2.1
`2.2
`i?
`62
`62
`52
`60
`52
`62
`62
`52
`52
`60
`60
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`Page 22 of 68
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`Win-tossed 3: Undontood by me,
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`Invent-d by
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`To Page No.
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`Page 22 of 68
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`/
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`Project No.
`BookNo. u_“__
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`11
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`From Page No._
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`FB4L, BFAB and RHE are lambda-type REI, MCPL, FBJL AND 2HFL are kappa—type
`hll = human lambda light
`hkl = human kappa light
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`a) residues between parentheses are included in beta~sheet based on backbone
`dihedral angles and hydrogen—bonding patterns
`b) letter repeats above sequences correspond to beta—sheet strands
`c) L1, L2, L3 correspond to hypervariable loops
`d) @ first residue is PCA = pyroglutamyl
`e) small letter in sequence = Ca-Ca distance between proteins > 1.0 A
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