`
`Voice of the Pharmacist
`
`Source: SDI’s Vector One®: National
`2010 Top 200 branded drugs by total prescriptions
`
`Rank
`
`Drug
`
`1
`2
`3
`4
`5
`6
`7
`8
`9
`10
`11
`12
`13
`14
`15
`16
`17
`18
`19
`20
`21
`22
`23
`24
`25
`26
`27
`28
`29
`30
`31
`32
`33
`34
`35
`
`Lipitor
`Nexium
`Plavix
`Singulair
`Lexapro
`Crestor
`Synthroid
`ProAir HFA
`Advair Diskus
`Cymbalta
`Diovan
`Ventolin HFA
`Diovan HCT
`Actos
`Seroquel
`Levaquin
`Lantus
`Nasonex
`Viagra
`Lyrica
`Celebrex
`Concerta
`Spiriva
`Premarin tabs
`Effexor XR
`Tricor
`Zetia
`Vytorin
`OxyContin
`Abilify
`Loestrin 24 Fe
`Vyvanse
`Cialis
`Suboxone
`Aricept
`
`Total
`Rxs
`37,523,566
`25,872,311
`25,000,508
`24,666,972
`23,000,456
`20,945,607
`20,272,359
`18,616,827
`16,580,931
`14,591,949
`14,360,575
`13,523,514
`11,480,540
`11,193,068
`10,260,420
`9,322,197
`8,960,452
`8,834,010
`8,829,457
`8,714,215
`8,643,515
`7,949,409
`7,738,168
`7,691,197
`7,603,949
`7,588,438
`7,398,986
`7,165,747
`6,869,557
`6,799,343
`6,693,687
`6,604,632
`6,584,896
`6,476,241
`6,252,862
`
`% Change from
`previous year
`-11.3%
`-1.7%
`-2.1%
`-0.5%
`-4.1%
`14.4%
`-4.5%
`-15.7%
`-4.7%
`-1.3%
`-3.2%
`68.4%
`-6.7%
`-3.5%
`-6.9%
`-12.4%
`-5.9%
`-7.9%
`-7.4%
`-5.1%
`-9.8%
`2.7%
`5.3%
`-14.7%
`-44.1%
`-23.1%
`-14.8%
`-25.3%
`7.5%
`6.0%
`65.5%
`31.3%
`5.2%
`24.2%
`-4.0%
`
`Rank
`
`Drug
`
`36
`37
`38
`39
`40
`41
`42
`43
`44
`45
`46
`47
`48
`49
`50
`51
`52
`53
`54
`55
`56
`57
`58
`59
`60
`61
`62
`63
`64
`65
`66
`67
`68
`69
`70
`
`Benicar
`Januvia
`Lunesta
`Ambien CR
`Niaspan
`Xalatan
`Levoxyl
`Benicar HCT
`Flovent HFA
`NuvaRing
`Lovaza
`Yaz
`NovoLog
`Combivent
`Namenda
`Detrol LA
`Ortho Tri-Cyclen Lo
`Lantus SoloSTAR
`Proventil HFA
`Aciphex
`Avapro
`Bystolic
`Adderall XR
`Symbicort
`Zyprexa
`Trilipix
`Boniva
`Avodart
`Glipizide XL
`Pristiq
`Lidoderm
`Humalog
`Vigamox
`Evista
`Flomax
`
`Total
`Rxs
`6,098,994
`5,919,456
`5,714,739
`5,687,633
`5,618,908
`5,516,848
`5,452,741
`5,215,681
`5,047,632
`4,756,490
`4,583,660
`4,567,146
`4,443,860
`4,270,924
`4,193,637
`4,160,847
`4,157,693
`4,035,957
`3,952,848
`3,897,030
`3,811,895
`3,666,287
`3,625,997
`3,618,811
`3,616,933
`3,608,974
`3,524,839
`3,466,894
`3,423,438
`3,412,354
`3,402,179
`3,343,036
`3,327,763
`3,296,079
`3,132,677
`
`% Change from
`previous year
`-10.8%
`5.5%
`7.5%
`-16.7%
`5.6%
`-3.3%
`-16.9%
`-12.7%
`9.5%
`1.7%
`12.0%
`-54.5%
`10.2%
`-5.1%
`4.2%
`-18.8%
`8.7%
`40.5%
`-30.3%
`-18.6%
`-17.2%
`62.6%
`-29.6%
`42.1%
`-0.9%
`84.2%
`-14.7%
`0.3%
`24.2%
`49.9%
`-2.6%
`-6.2%
`-1.9%
`-11.4%
`-73.1%
`
`1 Drug topicS
`
` June 2011
`
`Exhibit 1122
`
`IPR2017-00807
`ARGENTUM
`
`
`
`DrugTopics.com
`
`000001
`
`
`
`®
`
`Voice of the Pharmacist
`
`Source: SDI’s Vector One®: National
`2010 Top 200 branded drugs by total prescriptions
`
`Rank
`
`Drug
`
`71
`72
`73
`74
`75
`76
`77
`78
`79
`80
`81
`82
`83
`84
`85
`86
`87
`88
`89
`90
`91
`92
`93
`94
`95
`96
`97
`98
`99
`100
`101
`102
`103
`104
`105
`
`Chantix
`Avalide
`Protonix
`Cozaar
`Vivelle-DOT
`Vesicare
`Prempro
`Avelox
`Dexilant/Kapidex
`Focalin XR
`Strattera
`Xopenex HFA
`Actonel
`Travatan Z
`Levemir
`Lumigan
`Apri
`Levitra
`Geodon oral
`Micardis
`Exforge
`Coumadin tabs
`Janumet
`Ciprodex otic
`Valtrex
`Restasis
`Seroquel XR
`Micardis HCT
`Actonel 150
`Lotrel
`Tussionex
`Prometrium
`AndroGel
`Kariva
`Patanol
`
`Total
`Rxs
`2,980,917
`2,879,195
`2,848,122
`2,837,637
`2,832,173
`2,814,667
`2,702,035
`2,693,235
`2,675,863
`2,667,245
`2,606,700
`2,584,196
`2,558,636
`2,543,583
`2,535,211
`2,518,408
`2,394,198
`2,359,725
`2,332,901
`2,324,180
`2,267,437
`2,248,254
`2,245,817
`2,204,258
`2,180,482
`2,156,415
`2,101,144
`2,088,803
`2,045,479
`2,041,615
`2,024,442
`1,989,773
`1,969,279
`1,967,203
`1,960,988
`
`% Change from
`previous year
`-20.9%
`-17.6%
`-9.2%
`-64.0%
`1.6%
`6.2%
`11.7%
`-15.1%
`233.3%
`11.8%
`-7.8%
`-8.3%
`-37.6%
`33.6%
`29.6%
`2.8%
`10.5%
`-17.5%
`0.3%
`2.4%
`6.6%
`-18.6%
`14.9%
`4.2%
`-71.7%
`3.5%
`94.4%
`-1.3%
`12.5%
`-17.4%
`-39.0%
`-1.4%
`6.7%
`-15.8%
`-7.4%
`
`Rank
`
`Drug
`
`106
`Voltaren gel
`107
`Hyzaar
`108
`Thyroid, Armour
`109
`Nasacort AQ
`110
`Coreg CR
`111
`Qvar
`112
`Pataday
`113
`Xyzal
`114
`Humulin N
`115
`Vagifem
`116
`Toprol XL
`117
`Byetta
`118
`NovoLog Mix 70/30
`119
`Veramyst
`120
`Azor
`121
`Caduet
`122 Welchol
`123
`Actoplus Met
`124
`Provigil
`125
`Epipen
`126
`Aggrenox
`127
`Dilantin
`128
`Enablex
`129
`Alphagan P
`130
`Premarin vaginal
`131
`Xopenex
`132
`Uroxatral
`133
`Asmanex
`134
`Prevacid SoluTab
`135
`Moviprep
`136
`Avandia
`137
`Tekturna
`138
`Propecia
`139
`Ortho Evra
`140
`Solodyn
`
`Total
`Rxs
`1,931,594
`1,899,131
`1,893,236
`1,807,665
`1,782,976
`1,781,072
`1,755,473
`1,747,745
`1,715,002
`1,650,317
`1,650,078
`1,638,475
`1,633,160
`1,584,391
`1,562,043
`1,561,704
`1,560,389
`1,531,222
`1,517,573
`1,512,146
`1,497,553
`1,475,541
`1,466,634
`1,461,043
`1,452,843
`1,444,380
`1,419,250
`1,412,419
`1,393,708
`1,363,832
`1,345,507
`1,321,901
`1,319,959
`1,312,634
`1,311,733
`
`% Change from
`previous year
`34.3%
`-64.7%
`-43.6%
`-25.6%
`-7.2%
`30.4%
`16.4%
`-24.4%
`-4.4%
`-3.1%
`-67.6%
`-22.1%
`6.9%
`-9.9%
`21.5%
`-26.2%
`13.2%
`-3.4%
`-29.1%
`-1.1%
`-6.9%
`-4.9%
`3.0%
`-27.0%
`-4.6%
`-20.6%
`-4.4%
`-4.0%
`-4.9%
`21.7%
`-40.0%
`5.3%
`-9.4%
`-13.9%
`19.1%
`
`2 Drug topicS June 2011
`
`DrugTopics.com
`
`000002
`
`
`
`®
`
`Voice of the Pharmacist
`
`Source: SDI’s Vector One®: National
`2010 Top 200 branded drugs by total prescriptions
`
`Rank
`
`Drug
`
`141
`142
`143
`144
`145
`146
`147
`148
`149
`150
`151
`152
`153
`154
`155
`156
`157
`158
`159
`160
`161
`162
`163
`164
`165
`166
`167
`168
`169
`170
`
`Humulin 70/30
`Lanoxin
`Asacol
`Prevacid
`Atacand
`Nitrostat
`Combigan
`Halflytely bwl prep
`Relpax
`Novolin 70/30
`Femara
`Tamiflu
`Zovirax topical
`Lovenox
`Zymar
`Maxalt
`Estrace vaginal
`Exelon Patch
`Intuniv
`Allegra-D 24 Hour
`Astepro 0.15%
`Maxalt MLT
`Arimidex
`Amitiza
`Doryx
`Differin
`Clarinex
`Lotemax
`Astelin
`Transderm-Scop
`
`Total
`Rxs
`1,298,395
`1,265,185
`1,258,486
`1,248,021
`1,238,609
`1,220,125
`1,169,315
`1,128,414
`1,113,336
`1,106,168
`1,098,445
`1,094,916
`1,075,542
`1,057,051
`1,055,235
`1,028,658
`1,024,694
`1,008,200
`983,113
`975,833
`955,880
`949,328
`946,656
`941,191
`939,008
`913,676
`906,614
`905,561
`896,918
`883,269
`
`% Change from
`previous year
`-14.7%
`-41.2%
`-19.1%
`-90.5%
`-29.2%
`17.8%
`27.8%
`-28.9%
`-8.2%
`-1.0%
`-0.6%
`-85.3%
`-5.1%
`-22.2%
`-31.5%
`-7.5%
`7.4%
`24.9%
`>999
`-25.3%
`>999
`-8.3%
`-45.5%
`-1.8%
`13.4%
`-37.0%
`-43.2%
`1.3%
`-52.5%
`4.6%
`
`Rank
`
`Drug
`
`171
`Humulin R
`172
`Levothroid
`173
`Advair HFA
`174
`Truvada
`175
`Nuvigil
`176
`SF 5000 Plus
`177
`Yasmin 28
`178
`Bactroban
`179
`Ranexa
`180
`Metadate CD
`181
`Lamictal
`182
`Atrovent HFA
`183
`Simcor
`184
`Opana ER
`185
`Rhinocort Aqua
`186
`Humalog Mix 75/25 Pen
`187
`Carafate
`188
`Norvir
`189
`Aspir-Low
`190
`BenzaClin
`191
`Skelaxin
`192
`Duac Care System
`193 Wellbutrin XL
`194
`Arthrotec
`195
`Epiduo
`196
`Pulmicort Flexhaler
`197
`Omnaris
`198
`Ortho Tri-Cyclen
`199
`Prandin
`200
`Nevanac
`
`Total
`Rxs
`878,274
`869,398
`868,420
`866,743
`852,695
`838,699
`837,743
`824,689
`816,279
`810,541
`801,627
`800,659
`800,564
`794,188
`774,768
`769,785
`764,966
`762,060
`760,731
`759,929
`759,046
`755,382
`753,516
`752,560
`742,395
`735,413
`734,773
`732,714
`726,766
`725,667
`
`% Change from
`previous year
`-6.9%
`-40.2%
`22.0%
`-7.5%
`194.8%
`12.3%
`-28.7%
`-17.7%
`32.8%
`-6.8%
`-42.3%
`-5.7%
`14.9%
`39.4%
`-36.8%
`-14.7%
`7.5%
`-10.9%
`2.2%
`-45.3%
`-70.2%
`-15.4%
`-26.7%
`-15.7%
`43.5%
`-6.7%
`79.3%
`16.1%
`-15.0%
`16.1%
`
`3 Drug topicS June 2011
`
`DrugTopics.com
`
`000003
`
`