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2009 Exhibit: EXHIBIT 2009 361 Pat FH 102716 Office Action

Document IPR2021-01134, No. 2009 Exhibit - EXHIBIT 2009 361 Pat FH 102716 Office Action (P.T.A.B. Oct. 8, 2021)

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1023 Exhibit: US 20100168212 Popplewell

Document IPR2021-01134, No. 1023 Exhibit - US 20100168212 Popplewell (P.T.A.B. Jun. 21, 2021)

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1004 Exhibit: English Translation for JP Provisional

Document IPR2021-01134, No. 1004 Exhibit - English Translation for JP Provisional (P.T.A.B. Jun. 21, 2021)

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1040 Exhibit: Nakamura 2009

Document IPR2021-01134, No. 1040 Exhibit - Nakamura 2009 (P.T.A.B. Jun. 21, 2021)

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2013 Exhibit: EXHIBIT 2013 9,453,225 PH excerpt

Document IPR2021-01134, No. 2013 Exhibit - EXHIBIT 2013 9,453,225 PH excerpt (P.T.A.B. Oct. 8, 2021)

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2015 Exhibit: EXHIBIT 2015 9,447,416 Pat FH excerpt

Document IPR2021-01134, No. 2015 Exhibit - EXHIBIT 2015 9,447,416 Pat FH excerpt (P.T.A.B. Oct. 8, 2021)

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2027 Exhibit: EXHIBIT 2027 Patent Owner RFP

Document IPR2021-01134, No. 2027 Exhibit - EXHIBIT 2027 Patent Owner RFP (P.T.A.B. Feb. 2, 2022)

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1028 Exhibit: Kinali 2009

Document IPR2021-01134, No. 1028 Exhibit - Kinali 2009 (P.T.A.B. Jun. 21, 2021)

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3003 Exhibit: Ex 3003

Document IPR2021-01134, No. 3003 Exhibit - Ex 3003 (P.T.A.B. Feb. 3, 2022)

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1030 Exhibit: Wilton 2008

Document IPR2021-01134, No. 1030 Exhibit - Wilton 2008 (P.T.A.B. Jun. 21, 2021)

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1038 Exhibit: Goemans 2011

Document IPR2021-01134, No. 1038 Exhibit - Goemans 2011 (P.T.A.B. Jun. 21, 2021)

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2004 Exhibit: EXHIBIT 2004 YokotaA Renaissance for Antisense Oligonucleotide

Document IPR2021-01134, No. 2004 Exhibit - EXHIBIT 2004 YokotaA Renaissance for Antisense Oligonucleotide (P.T.A.B. Oct. 8, 2021)

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2016 Exhibit: EXHIBIT 2016 948 Pat FH 12116 Response

Document IPR2021-01134, No. 2016 Exhibit - EXHIBIT 2016 948 Pat FH 12116 Response (P.T.A.B. Oct. 8, 2021)

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2021 Exhibit: EXHIBIT 2021 Corey Nucleic Acid Research 2018

Document IPR2021-01134, No. 2021 Exhibit - EXHIBIT 2021 Corey Nucleic Acid Research 2018 (P.T.A.B. Oct. 8, 2021)

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2019 Exhibit: EXHIBIT 2019 533 App 12 14 2018 response

Document IPR2021-01134, No. 2019 Exhibit - EXHIBIT 2019 533 App 12 14 2018 response (P.T.A.B. Oct. 8, 2021)

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