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2024 Exhibit: Exhibit 2024

Document IPR2018-00943, No. 2024 Exhibit - Exhibit 2024 (P.T.A.B. Feb. 7, 2019)

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2023 Exhibit: Exhibit 2023

Document IPR2018-00943, No. 2023 Exhibit - Exhibit 2023 (P.T.A.B. Feb. 7, 2019)

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2037 Exhibit: Exhibit 2037

Document IPR2018-00943, No. 2037 Exhibit - Exhibit 2037 (P.T.A.B. Feb. 7, 2019)

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2048 Exhibit: Exhibit 2048

Document IPR2018-00943, No. 2048 Exhibit - Exhibit 2048 (P.T.A.B. Feb. 7, 2019)

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1082 Exhibit: Malcom Rowland and Thomas N Tozer, Clinical Pharmacokinetics Con...

Document IPR2018-00943, No. 1082 Exhibit - Malcom Rowland and Thomas N Tozer, Clinical Pharmacokinetics Concepts and Applications 3rd ed 1995 (P.T.A.B. May. 7, 2019)

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1069 Exhibit: Bioavailability and Bioequivalence Studies for Orally Administered Dr...

Document IPR2018-00943, No. 1069 Exhibit - Bioavailability and Bioequivalence Studies for Orally Administered Drug Products General Considerations, Guidance for Industry (P.T.A.B. May. 7, 2019)

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2040 Exhibit: Exhibit 2040

Document IPR2018-00943, No. 2040 Exhibit - Exhibit 2040 (P.T.A.B. Feb. 7, 2019)

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2043 Exhibit: Exhibit 2043

Document IPR2018-00943, No. 2043 Exhibit - Exhibit 2043 (P.T.A.B. Feb. 7, 2019)

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2025 Exhibit: Exhibit 2025

Document IPR2018-00943, No. 2025 Exhibit - Exhibit 2025 (P.T.A.B. Feb. 7, 2019)

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2022 Exhibit: Exhibit 2022

Document IPR2018-00943, No. 2022 Exhibit - Exhibit 2022 (P.T.A.B. Jan. 17, 2019)

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1064 Exhibit: Bertoletti et al, Effect of liver cirrhosis on the systemic availability of n...

Document IPR2018-00943, No. 1064 Exhibit - Bertoletti et al, Effect of liver cirrhosis on the systemic availability of naltrexone in humans (P.T.A.B. May. 7, 2019)

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1077 Exhibit: Krishna et al, Increased Intracellular Drug Accumulation and Complet...

Document IPR2018-00943, No. 1077 Exhibit - Krishna et al, Increased Intracellular Drug Accumulation and Complete Chemosensitization Achieved in Multidrug Resistant Solid Tumors by Co Administering...

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1089 Exhibit: Malcolm Rowland and Thomas N Tozer, Clinical Pharmacokinetics an...

Document IPR2018-00943, No. 1089 Exhibit - Malcolm Rowland and Thomas N Tozer, Clinical Pharmacokinetics and Pharmacodynamics Concepts and Applications 4th ed2011 (P.T.A.B. May. 7, 2019)

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2045 Exhibit: Exhibit 2045

Document IPR2018-00943, No. 2045 Exhibit - Exhibit 2045 (P.T.A.B. Feb. 7, 2019)

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2054 Exhibit: Exhibit 2054

Document IPR2018-00943, No. 2054 Exhibit - Exhibit 2054 (P.T.A.B. Feb. 7, 2019)

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