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5 Mandatory Notice: Patent Owners Mandatory Notices

Document IPR2019-00450, No. 5 Mandatory Notice - Patent Owners Mandatory Notices (P.T.A.B. Feb. 19, 2019)
The patent owner provides the following notice pursuant to 37 CFR §42.8(a)(2).
Real parties-in-interest Neurelis, Inc. (“Neurelis”) owns the involved patent.
Related matters The petitioner has filed two additional inter partes review petitions
Neurelis has an application (15/470,498) that claims benefit under 35 U.S.C. 120 to the application that issued as the involved patent.
above counsel, is of record for the involved patent.
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1 Power of Attorney: Power of Attorney

Document IPR2019-00450, No. 1 Power of Attorney - Power of Attorney (P.T.A.B. Jan. 29, 2019)
In accordance with 37 CPR.
I have authority to sign this document on behalf of Petitioner Aquestive
Mark Sc e1 Aquestive Therapeutics, Inc.
Title: Chief Innovation & Technology Officer Date
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2002 Exhibit: Food Drug Administration, Grant Fast Track IND 112621 NRL 1 diaze...

Document IPR2019-00450, No. 2002-70 Exhibit - Food Drug Administration, Grant Fast Track IND 112621 NRL 1 diazepam intranasal solution 27 Dec 2016 (P.T.A.B. May. 6, 2019)

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2005 Exhibit: KM Fiest et al, Prevalence and Incidence of Epilepsy, A Systematic R...

Document IPR2019-00450, No. 2005-73 Exhibit - KM Fiest et al, Prevalence and Incidence of Epilepsy, A Systematic Review and Meta Analysis of International Studies, 88 Neurology 296 17 Jan 2017 (P.T...

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2001 Exhibit: Centers for Disease Control and Prevention, Epilepsy Fast Facts 9 Ap...

Document IPR2019-00450, No. 2001-69 Exhibit - Centers for Disease Control and Prevention, Epilepsy Fast Facts 9 Apr 2019, available at httpswwwcdcgovepilepsyaboutfast factshtmCDC AA refValhttps%...

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2004 Exhibit: Centers for Disease Control and Prevention, Putting Collective Wisdo...

Document IPR2019-00450, No. 2004-72 Exhibit - Centers for Disease Control and Prevention, Putting Collective Wisdom to Work for People with Epilepsy Nov 2016 (P.T.A.B. May. 6, 2019)

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2003 Exhibit: Howard LeWine, MD, Quick Injection Helps Stop Epileptic Seizures, H...

Document IPR2019-00450, No. 2003-71 Exhibit - Howard LeWine, MD, Quick Injection Helps Stop Epileptic Seizures, Harvard Health Blog 23 Feb 2012, available at httpswwwhealthharvard edublogquick in...

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1045 Exhibit: Maitani, et al, Design of ocularlacrimal and nasal systems through an...

Document IPR2019-00450, No. 1045-63 Exhibit - Maitani, et al, Design of ocularlacrimal and nasal systems through analysis of drug administration and absorption, Journal of Controlled Release, Volume 4...

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1007 Exhibit: Part 2 ¿¿¿ Pages 401 800 File History for Non Provisional Patent Applic...

Document IPR2019-00450, No. 1007-16 Exhibit - Part 2 ¿¿¿ Pages 401 800 File History for Non Provisional Patent Application Serial No 12413,439, filed March 27, 2009 ¿¿¿439 FH (P.T.A.B. Jan. 29, 2019)

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1013 Exhibit: Sonne, US Patent No 6,193,985, Tocopherol Compositions For Delive...

Document IPR2019-00450, No. 1013-29 Exhibit - Sonne, US Patent No 6,193,985, Tocopherol Compositions For Delivery Of Biologically Active Agents, issued February 27, 2001 Sonne (P.T.A.B. Jan. 29, 2...

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1007 Exhibit: Part 9 ¿¿¿ Pages 3201 3488 File History for Non Provisional Patent App...

Document IPR2019-00450, No. 1007-23 Exhibit - Part 9 ¿¿¿ Pages 3201 3488 File History for Non Provisional Patent Application Serial No 12413,439, filed March 27, 2009 ¿¿¿439 FH (P.T.A.B. Jan. 29, 2019...

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1031 Exhibit: Rowe et al, Handbook of Pharmaceutical Excipients, Fourth Edition 2...

Document IPR2019-00450, No. 1031-47 Exhibit - Rowe et al, Handbook of Pharmaceutical Excipients, Fourth Edition 2003, Monographs, American Pharmaceutical Association, Washington DC Rowe (P.T.A...

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1045 Exhibit: Maitani, et al, Design of ocularlacrimal and nasal systems through an...

Document IPR2019-00450, No. 1045-63 Exhibit - Maitani, et al, Design of ocularlacrimal and nasal systems through analysis of drug administration and absorption, Journal of Controlled Release, Volume 4...

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1010 Exhibit: US Patent Application Publication No US 20090258865, Administratio...

Document IPR2019-00450, No. 1010-26 Exhibit - US Patent Application Publication No US 20090258865, Administration of Benzodiazepine Compositions, Serial No 12413,439 Cartt¿¿¿865 (P.T.A.B. Jan. 2...

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1016 Exhibit: Kee et al, US Patent No 5,369,095, Compositions And Method Compr...

Document IPR2019-00450, No. 1016-32 Exhibit - Kee et al, US Patent No 5,369,095, Compositions And Method Comprising Substituted Glycosides As Mucus Membrane Permeation Enhancers, issued No...

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