• All Courts
  • Federal Courts
  • Bankruptcies
  • PTAB
  • ITC
Track Search
Export
Download All
Displaying 114-128 of 155 results

1011 Exhibit: Meezan et al, US Patent Application Publication No US 20060046962, Absorption Enhancers for Drug Administration, Serial No 11127,786, published March 2, 2006 Meezan¿¿¿962

Document IPR2019-00449, No. 1011 Exhibit - Meezan et al, US Patent Application Publication No US 20060046962, Absorption Enhancers for Drug Administration, Serial No 11127,786, published March 2...
[0009] The present invention also provides a method of treating diabetes including administering to a subject in need thereof via the oral, ocular, nasal, nasolacrimal, inhalation or pulmonary, or oral cavity (sublingual or Buccal cell), a blood glucose reducing amount of a therapeutic composition, for example, an incretin mimetic agent or a functional equiva lent thereof, and an absorption increasing amount of a suitable nontoxic, nonionic alkyl glycoside having a hydro phobic alkyl group joined by a linkage to a hydrophilic saccharide, thereby increasing the absorption of incretin mimetic agent or insulin and loWering the level of blood glucose and treating diabetes in the subject.
The linkage betWeen the hydrophobic alkyl group and the hydro philic saccharide can include, among other possibilities, a glycosidic, thioglycosidic (Horton), amide (Carbohydrates as Organic RaW Materials, F. W. Lichtenthaler ed., VCH Publishers, NeW York, 1991), ureide (Austrian Pat. 386,414 (1988); Chem.
A phar maceutically acceptable carrier can also be selected from substances such as distilled Water, benZyl alcohol, lactose, starches, talc, magnesium stearate, polyvinylpyrrolidone, alginic acid, colloidal silica, titanium dioxide, and ?avoring agents.
Other compounds include, for example, nicotine, interferon (e.g., alpha, beta, gamma), PYY, GLP-1, synthetic exendin-4 (Exenatide), parathyroid hormone, and human groWth hor mone or other loW molecular Weight peptides and proteins.
The sustained release format can be an ocular insert, erodible microparticulates, sWelling mucoadhesive particulates, pH sensitive micropar ticulates, nanoparticles/latex systems, ion-exchange resins and other polymeric gels and implants (Ocusert, AlZa Corp., California; Joshi, A., S. Ping and K. J. Himmelstein, patent application WO 91/19481).
cite Cite Document

1047 Exhibit: Gwozdz Assignment of Provisional in Non Provisional Case, dated Ap...

Document IPR2019-00449, No. 1047 Exhibit - Gwozdz Assignment of Provisional in Non Provisional Case, dated April 21, 2008, recorded September 23, 2010 Gwozdz Assignment (P.T.A.B. Jan. 28, 2019)

cite Cite Document

1044 Exhibit: USP NF 2003, The United States Pharmacopeia, The National Formu...

Document IPR2019-00449, No. 1044 Exhibit - USP NF 2003, The United States Pharmacopeia, The National Formulary, United States Pharmacopeial Convention, Inc ¿¿¿USPNF¿¿¿ (P.T.A.B. Jan. 28, 2019)

cite Cite Document

1034 Exhibit: Edman I et al, D Routes of Delivery Case Studies 1 Nasal delivery of p...

Document IPR2019-00449, No. 1034 Exhibit - Edman I et al, D Routes of Delivery Case Studies 1 Nasal delivery of peptide drugs, Advanced Drug Delivery Reviews, 8 1992 165 177 Edman I (P.T.A.B. Jan....

cite Cite Document

1038 Exhibit: Bara, US Patent Application Publication No US20060178290, Serial N...

Document IPR2019-00449, No. 1038 Exhibit - Bara, US Patent Application Publication No US20060178290, Serial No 10563,967, published August 10, 2006 Bara (P.T.A.B. Jan. 28, 2019)

cite Cite Document

1037 Exhibit: Colombo, Mucosal Drug Delivery, Nasal, pp 592 605, Vol 2, Encyclop...

Document IPR2019-00449, No. 1037 Exhibit - Colombo, Mucosal Drug Delivery, Nasal, pp 592 605, Vol 2, Encyclopedia of Controlled Drug Delivery Mathiowitz, editor, John Wiley Sons, 1999 Colombo (P.T...

cite Cite Document

1045 Exhibit: Maitani, et al, Design of ocularlacrimal and nasal systems through an...

Document IPR2019-00449, No. 1045 Exhibit - Maitani, et al, Design of ocularlacrimal and nasal systems through analysis of drug administration and absorption, Journal of Controlled Release, Volume 49, I...

cite Cite Document

1028 Exhibit: Ivaturi et al, Pharmacokinetics and tolerability of intranasal diazepam...

Document IPR2019-00449, No. 1028 Exhibit - Ivaturi et al, Pharmacokinetics and tolerability of intranasal diazepam and midazolam in healthy adult volunteers, Acta Neurol Scand 2009 Nov1205353 7 doi 1...

cite Cite Document

1039 Exhibit: Behl et al, Effects of physicochemical properties and other factors on...

Document IPR2019-00449, No. 1039 Exhibit - Behl et al, Effects of physicochemical properties and other factors on systemic nasal drug delivery, Advanced Drug Delivery Reviews 29 1998 89¿¿¿116 Behl (P...

cite Cite Document

1036 Exhibit: Deshmukh et al, Lorazepam in the Treatment of Refractory Neonatal ...

Document IPR2019-00449, No. 1036 Exhibit - Deshmukh et al, Lorazepam in the Treatment of Refractory Neonatal Seizures, Am J Dis Child 1986140101042 1044 Deshmukh (P.T.A.B. Jan. 28, 2019)

cite Cite Document

1043 Exhibit: Knoester, et al, Pharmacokinetics and pharmacodynamics of midazo...

Document IPR2019-00449, No. 1043 Exhibit - Knoester, et al, Pharmacokinetics and pharmacodynamics of midazolam administered as a concentrated intranasal spray A study in healthy volunteers, Br J C...

cite Cite Document

1016 Exhibit: Kee et al, US Patent No 5,369,095, Compositions And Method Compr...

Document IPR2019-00449, No. 1016 Exhibit - Kee et al, US Patent No 5,369,095, Compositions And Method Comprising Substituted Glycosides As Mucus Membrane Permeation Enhancers, issued Novem...

cite Cite Document

1018 Exhibit: Tenta, US Patent No 3,949,072, Seborrheic Keratosis Treatment, iss...

Document IPR2019-00449, No. 1018 Exhibit - Tenta, US Patent No 3,949,072, Seborrheic Keratosis Treatment, issued April 6, 1976 Tenta (P.T.A.B. Jan. 28, 2019)

cite Cite Document

1019 Exhibit: Ueda et al, US Patent No 4,657,901, Pharmaceutical Composition, iss...

Document IPR2019-00449, No. 1019 Exhibit - Ueda et al, US Patent No 4,657,901, Pharmaceutical Composition, issued April 14, 1987 Ueda (P.T.A.B. Jan. 28, 2019)

cite Cite Document

1017 Exhibit: Cartt et al, WO 2008137960, Nasal Administration Of Benzodiazepine...

Document IPR2019-00449, No. 1017 Exhibit - Cartt et al, WO 2008137960, Nasal Administration Of Benzodiazepines, published November 13, 2008, International filing date May 7, 2008 PCTUS200806296...

cite Cite Document
<< 1 2 3 4 5 ... 8 9 10 11 >>