DEGRADANT COMPOUND IN A MEDICAMENT, 18/250,921, No. LPIYQFHJGREENX5 (U.S. Pat. App. Nov. 28, 2023)

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DEGRADANT COMPOUND IN A MEDICAMENT, 18/250,921, No. LPIYQFHJGREENX5 (U.S. Pat. App. Nov. 28, 2023)

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7
`
`Remarks
`
`Rhett Mead SCHIFFMAN
`
`Application No. 18/250,921
`
`Upon entry of the foregoing amendment, claims 1, 8, 12, 13, 15, 20, 24, 28, 43, 48, 49, 50,
`
`61-63, 67, 71, 73-75, and 82 are pending in the application, with claims 1, 20, 43, 49, 50, 61, and 73
`
`being the independentclaims. Claims 1, 8, 12, 15, 20, 24, 28, 43, 48, 61, 63, 67, 71, 73, 75, and 82
`
`are amended. Claims 2-7, 9-11, 14, 16-19, 21-23, 25-27, 29-42, 44-47, 51-60, 64-66, 68-70, 72, 76-
`
`81, and 83-146 are canceled without prejudice to or disclaimer of the subject matter therein.
`
`Claims 1, 20, and 61 are amendedto recite wherein the formulation comprises less than 5 wt
`
`% impurity A after storage for at least 5 months, and claim 8 is amended wherein the formulation
`
`comprises less than 1 wt % impurity A after storage at 25 °C and 40% relative humidity for at least 5
`
`months. Support for these amendments may be found, e.g., in Jf] [0106] and [0114] of the as filed
`
`specification. Claims 24, 43, and 67 are amendedto recite wherein the formulation comprisesless
`
`than 2 wt % impurity B after storage for at least 5 months, and claim 28 is amended to recite wherein
`
`the formulation comprises less than 0.25 wt % impurity B after storage at 25 °C and 40% relative
`
`humidity for at least 3 months. Support for these amendments may be found, e.g., in J] [0110] and
`
`[0114] of the as filed specification. Claims 73 and 82 are amendedto recite wherein the amelioration
`
`or reduction of presbyopia is effective for at least 6 hours. Support for these amendments may be
`
`found, e.g., in § [0137] of the as filed specification. Claims 12, 15, 24, 48, 63, 67, 71, 75, and 82 are
`
`amended to adjust their dependencies.
`
`These changes introduce no new matter, and their entry is respectfully requested.
`
`Atty. Dkt. No. 4902.0110003
`
`

`-ll-
`
`Conclusion
`
`Rhett Mead SCHIFFMAN
`Application No. 18/250,921
`
`Promptand favorable consideration of this Preliminary Amendmentis respectfully requested.
`
`Applicant believes the present application is in condition for allowance. If the Examinerbelieves, for
`
`any reason, that personal communication will expedite prosecution of this application, the Examiner
`
`is invited to telephone the undersigned at the number provided.
`
`Respectfully submitted,
`
`STERNE, KESSLER, GOLDSTEIN & FOX P.L.L.C.
`
`/Marsha Rose Gillentine, Reg. No. 58,403/
`
`Marsha Rose Gillentine
`Attorney for Applicant
`Registration No. 58,403
`
`Date:__November 28, 2023
`
`1101 K Street, N.W.
`10" Floor
`Washington, D.C. 20005
`(202) 371-2600
`
`20080165.1
`
`Atty. Dkt. No. 4902.0110003
`
`

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