PCT
`
`REQUEST
`
`The undersigned requests that the present
`international application be processed
`according to the Patent Cooperation Treaty.
`
` For receiving Office use On) sassy
`y
`;
`PCT/US19/56693
`: international Application No.
`17 October 2019 (17.10.2019)
`i International Filing Date
`
`
`
`
`
`| sonia9$oragent'ssFilenisi 205961-0028-00WO
`
`f,798
`
`
`
`MIDSTREAM URINE COLLECTION
`
`Box No.
`
`in This person is also inventor
`APPLICANT
`(Familynamefo owedbyg iname, for alegaler
`g
`depostal code andname ofcountry. The country of
`ress indicatedin ‘his |i
`t's State (thatis, country) ofresidence ifno State ofresidenceis indicated below.)
`ThomasJefferson University
`901 Wainut Street, Innovation Pilar
`Philadelphia, PA 19107
`United States of America
`
`| E-mail authorization: Marking one ofthe check-boxes below authorizesthe recerving Office, the Intemational Searching Authority, the
`International Bureau and the International Preliminary Examining Authority to use the e-mail address indicated in this Box to send,|
`notifications issued in respect ofthis international application to that e-mail address ifthose offices are willingto do so.
`i
`Ff] as advance copies followed by paper notifications; or
`24} exclusively in electronic form (no paper notifications will be sent).
`E-mail address: dockets @riversidelaw.com
`State (that is, country) of nationality:
`
`i State (hat is, country) ofresidence:
`US
`e States indicated i
`> Sunplement:
`St afl
`desionate
`,
`personis applicant
`{| he States indicated in the Supplemental Box
`<I ali designated States
`forthe purposes of:
`Box No. GE
`FORTHER APPLICANT(S) AND/OR (FURTHER) INVENTOR(S)
`
`Box No. FV AGENT OR COMMON REPRESENTATIVE; OR ADDRESS FOR CORRESPONDENCE
`The person identified belowis hereby/has been appointed to act on behalf
`f
`it
`| common
`°
`of the applicant(s) before the competent International Authoritiesas:
`representative
`Name and address: (Family namefollowed bygiven name;for a legalentity, full official designation.|Telephone No.
`The address must include postal code and name ofcountry)
`245-268-3888
`Ryan D. Artis
`pare
`~:
`.
`-
`Facsimile No.
`Riverside Law, LLP
`°245.968-3871
`
`Glenhardie Corporate Center
`xz
`et registration No. with the Office
`ge
`1285 Drummers Lane, Suite 202
`6
`Wayne, PA 19087
`United States of America
`E-mail authorization: Marking one of the check-boxes below authorizes the receiving Office, the International Searching Authority, the
`International Bureau and the International Preliminary Examining Authority to use the e-mail address indicated in this Box to send,|
`notifications issued in respect of this international applicationto that e-mail address if those offices are willing to do so.
`'
`F"] as advance copies followed bypaper notifications; or
`Be exclusively in clectronic form (no paper notifications will be sent).
`E-mailaddress: dockets @riversidelaw.com
`Address for correspondence: Mark this check-box where no agent or commonrepresentative is/has been appointed and the
`space above is used instead fo indicate a
`specta] address to which correspondence should be sent.
`
`Form PCT/RO/101 (first sheet) (uly 2017)
`
`See Notes to the request form
`
`

`

`Box No. tik
`
`FURTHER APPLICANT(S) AND/OR WURTHER) INVENTOR(S)
`
`2...
`
`ifnone ofthe following sub-boxesis used, this sheet should not be included in the request.
`4,
`Name and address: (FamilynameJollowedbygivenname: for alegalentity,jfull officialidesignation. This person is:
`The address must include postal code and name ofcountry.
`The country ofthe address indicated in this
`Box is the applicant's State (that is, country) ofresidence ifno State ofresidence is indicatedbelow.)i| applicant onky
`VAROTSIS, Dante
`| applicant and inventor
`4232 Chestnut St, Apt. 4002
`DS)
`inventor only (Ufthis check-box
`Philadelphia, PA 19107
`ft is marked, do notfill in below.)
`United States of America
`
`Applicant’s registration No. withthe Office
`
`State (that is, country) of nationality:
`US
`ci
`ates
`This person is applicant
`| all designated States
`for the purposes of:
`tyfull official designation.|This person is:
`Name and address: (Family namefollowed by givername; for alegal enti
`the acidressindicatedinthis
`.
`The address must include postal code and nameofcountry. The country of’
`Box is the applicant's Stote (thatis, country} ofresidenceifno State ofvesidenceis indicated below.)
`applicant only
`DIFRANCO, Anthony
`4329 Terrace Street
`Philadelphia, PA 19128
`United States of America
`
`State (that is, country) of residence:
`US
`
`[| the States indicated in the Supplemental Box
`
`
`
`eee and inventor
`enor onky (ifthis check-box
`isnarked, do notfill in below)
`
`
`State (that is, country} ofnationality :
`State (drat is, country) ofresidence:
`US
`US
`all
`decion:
`State.
`This person is applicant
`fj all designated State
`for the purposes of.
`[| the States indicated in the Supplemental Box
`
`Applicant’s registrationNo. with the Office
`
`Name andaddress: (Family namefollowed by givenname, jora legal entity,jull official designation.|This personis:
`The address must includepostalI code and name oofcountry.
`The countryofthe addressindicated in this
`Boxts the applicant’s State (that is, country) of,residence ifne State ofresidence ts indicatedbelow}
`[| applicant only
`NEELY, Christopher
`rj applicant and inventor
`7219 Myrtle Drive
`S j
`inventor only (ifthis check-box
`Macungie, PA 18062
`is marked, do notfill in below)
`United States of America
`
`Applicant's registration No. withthe Office
`
`State (thatis, country) of nationality:
`US
`
`State (that is, country) of residence:
`
`deci
`ates
`This personis applicant
`[J all designated States
`for the purposesof:
`Name and address: (Familyname jollewedbygivenname, jor
`alegal entity,full official designation.|This personis:
`The addvess must inctude postal code and name of.country. The countryofthe addressindicated inthis
`Box is the applicant's State (thatis, country) ofresidenceifvio State ofresidenceis indicatedbelow.)
`i applicant only
`xU, Helen
`[| applicant and inventor
`1106 Fitzwater Street
`inventor only Ffthis check-bbox
`Philadelphia, PA 19147
`is marked, do notfill in below
`
`United States of America
`
`[| the States indicated in the Supplemental Box
`
`Applicant's registration No. withthe Office
`
`State (that is, country) of nationality:
`{
`,
`ty,
`Ly
`US
`feihepurpo§applicant [| all designated States
`
`ountry) of residence:
`
`[| the Staics indicated in the Suppicmental Box
`
`| Further applicants and/or (further) inventors are indicated on another continuation sheet.
`
`Form PCT/RO/1G¢1 (continuation sheet) July 2017)
`
`See Notes to the requestform
`
`

`

`Supplemental Box
`
`ifthe Supplemental Box is not used,
`
`request,
`
`¢Ra
`if, in any ofthe Boxes, except Boxes Nos. VIL()) to (vy) for which
`aspecial continuation boxisprovided, the Space!issinsuffiicient
`rnishail the information: in such
`case, write “Conti
`j
`Continuation of Box No. RY:
`of Box
`(indicate the number ofthe Box) andfurnish the
`informationin the sume manner as required according to the
`aptions ofthe Box in which the space was insufficient,
`in
`particular:
`ifmore than onePerson is to be indicated as applicant and/or
`invertor and no “continuation sheet” is available: in such
`case, write “Continuation ¢ofBoxNo. LH?” andindicatefor each
`additionaliperson the sametype ofinformation as requiredi
`Box No. Hf, The country oftithe addre288 indicated inthis Box is
`the applicant’‘s State (thatis, country) afresidence ifno State of
`residenceis indicaled below;
`if, in Box No. H or in anyofthe sub-boxes ofBox No. [1f, the
`indication “the States indicatediin the SupplementalBox”is
`checked:
`in:
`case, write “Continuation ofBox No. if” or
`“%ContinuationosowVo. FT”or “ContinuationofBoxe No.
`IF
`and No. UI” ¢
`nase
`may he}, indicate the name of the
`applicant(s) involvedand, nextto (each) such name, the State(s)
`fandvor, where applicable, ARIPO, Eurasian, European or
`OAPI patent) for the purposes ofwhich the named personis
`applicant;
`if, in Box No. Uf or in any ofthe sub-boxes ofBox No. IIE, the
`inventor or the inventor/applicant is not ‘Inventor for the
`purposes ofall designated States:
`in such case, write
`“Continuation ofBox Ne. HF” on “Continuation ofBoxNo. ip
`or “Continuation1 ofBoxes
`HandNo. HI” (as the case may
`be}, indicate the name of the inventor(s) and, next to (each)
`such name,
`the State(s) (andor, where applicable, ARIPO,
`Eurasian, European or OAPIpatent) for thepurposes ofwhich
`the namedperson is inventor;
`if, in addition to the agents) iindicated in Box No. IV, there are
`further agents:
`in sue)fi case, write “Continuation of
`Box No. IV” andindicatee fvvr eachfurther ageni ihe sametype
`ofinformation as requiredin Box No. iV;
`if, in BoxNo.VT, there are move than three earlier applications
`whoseepriorityis claimed:
`in such case, write
`Fedination
`if Box No. VI" andindicate for each additional cartier
`application the s
`type ofinformation as required
`SQM
`in Box No. Vi.
`
`ALLEN, Justin
`ALLEN, Scotti E.
`ARTIS, Ryan
`CHEN, Ming
`FONVILLE, Natalie
`FRAIND, ALICIA
`HAAS, Dennis
`NGUYEN, Quang
`NIGON, Philip D.
`SINGH, Pallab
`SLAUGHTER, Alison
`Riverside Law, LLP
`Glenhardie Two Corporaie Center
`1285 Drummers Lane, Suite 202
`Wayne, PA 19087
`us
`
`10872; 126542; 127528,160245
`
`Tek (215) 268-3888
`Fax: (215) 268-3874
`the practitioners associated with CustomerNos.
`
`ofthe wishthat
`ifthe applicant intends to make anindication9,
`the international application be treated, in certain designated
`States, as an applicationfor a patent ofaddition, certificate of
`addition, inventor's certificate ofaddition orutility
`certificate
`ofaddition:
`in such case, write the name or two-letter code of
`each designated State concerned undthe indication “patent ef
`addition,” “certificate ofaddition,” “inventar’s certificate of
`addition” or “utility certificate ofaddition,” the number ofthe
`parent application or parent patent or otherparent grant and
`the date ofgrant ofthe parentpatent or otherparentgrant or
`the date offiling ofthe parent application (Rules 4.]](anD
`and49bis.Ifa) or (bl).
`
`ifthe applicuni intends io make an indication ofthe wish thai
`the international application he treated, in the United States of
`America, as a continuation or continuation-in-part of an
`earlier application:
`in such case, write “United States of
`America” or “US” and the indication “continuation” or
`“continuation-in-part” and the number andthefiling date of
`the parent application (Rules 4.1 1a} (ii) and 49bis. lid).
`
`Form PCT/RO/101 (supplemental sheet) (July 2017)
`
`See Notes to the requestform
`
`

`

`Box Ne. V
`
`DESIGNATIONS
`
`Sheet No.
`
`...4...
`
`Thefiling ofthis request constitutes unnader Rule 4.9(a) the designation of all Contracting States bound by the PCTon the mternational
`filing datc, for the grant of covery kind of protection available and, where applicablo, for the grant of both regional and national patents.
`However,
`Cc} DE Germany is net designated for any kind of national protection
`| IP Japan is not designated for any kind of national protection
`CI KR Republic of Koreais not designated for any kind of national protection
`(The check-boxes above mayonlybe used to exclude (irrevocably) the designations concernedif, at the time of filing or subsequently under
`Rule 26bis.1, the international application
`contains in Box No. V1 a priority claimto an earlier national applicationfiled in the particular
`State concerned, in order to avoid the ceasing ofthe effect, under the national law, ofthis earlier national application.)
`
`
`
`Box No. Vi PRIORITY CLAIM AND DOCUMENT
`
`The priority of the following earlier application(s) is hereby claimed:
`
`
`Where cartier applicationis:
`re ae -
`a ;
`;
`.
`national application?)
`repional application:
`jintemational application:
`country or Member)
`“regional Office
`receiving Office
`oF WTO
`
`
`
`
`
`Filing date
`of earlier application
`(day/month/year)
`
`Number
`of earlier application
`
`17 October 2018
`
`62/746 948
`
`item (1)
`
`item (3)
`
`Cd Further priortty claims are indicatedin the Supplemental Box.
`
`Furnishingthe priority document(s):
`The receiving Office is requested to prepare and transmit to the International Bureana certified copyof the earlier application(s)
`(onlyifthe earlier application(s) wasfiled withthe receiving € ficewwhich, Jor thepurposes of
`this international application, is
`ihe receiving Office) wWentified above:as!
`other, see Supplemental Box
`El
`item (3)
`C1}
`item (2)
`all items
`CI item (1)
`Cl
`The International Bureau is requested to obtain froma digital library a certified copyof the earlier application(s) identified above,
`using, where applicable, the access code(s) indicated below (ifthe earlier application(s) is available to itfrom a digital library):
`
`CI item (1)
`access code
`
`i] item(2)
`access“ode
`
`CI Hom)
`ACCESS
`
`CJ other, sec
`Supplemental Box
`
`the receiving Office is requested to restore the right of prority for the earlter application(s) identified
`Restore the right of priority:
`above or in the Supplemental Box as item(s) (
`).
`(See also the Notes te Box No. VF; further
`information must be provided to support a request to restore the right ofpriority.
`
`Incorporation by reference: where an clement of the international application referredto in Article 11¢1)Gid(d) or (2) of a part of
`the description, claims or drawings referred to in Rule 20.5(a) is not otherwise contained in this international application but is
`completely contained in an szslicer.application whose priority is claimed on the date on which one or more elements referred to in
`Article 11(1)Gii) were first received by the receiving Office, that element or part is, subject to confirmation under Rule 20.6,
`incorporated by reference in this international application for the purposes of Rule 20.6.
`
`Box No. VIE INTERNATIONAL SEARCHING ADTHORITY
`
`Cheice of International Searching Authority (ISA) (/fmore than one International Searching Authority is competent to carry out the
`international search, indicate the Authority chesen; the two-letter code maybe used):
`isa/ US
`
`Form PCT/RG/1O1 (secend sheet) (July 2017)
`
`See Notes to the request form
`
`

`

`
`
`Continuation of Box Ne. VIE USE OF EARLIER SEARCH AND CLASSIFICATION RESULTS
`
`1. Request by the applicant under Rule 4,12
`1.1 [[]
`The ISAindicated in Box No. VIL is requested to take into accountthe results of the carlier search(es) indicated below
`(see also Notes to Continuation of Box No. VTE, item [; use ofresults ofmore than one earlier search)
`Filing date (day/monthyear)
`Application Number
`Country (or regional Office)
`
`this international applicationis the same, or substantialfy the same, as the application in respect of
`Statement (Rule 4.12Gi)}:
`which the earlier search was carried out except, where applicable, that it is filed in a different language.
`Submission of the earlier search results, where necessary*
`Availability of documents (Rules 124is.1(¢) and (d) and 12is.2(b)): the following documents are available to the ISA in
`a form and a manner acceptable to it, and therefore DO NOTneed to be submitted by the applicantto the recering Office, or
`to the ISA.
`
`copy ofthe results of the earlier search,
`a copy ofthe earlier application,
`a translation of the carlier application into a language whichis accepted by the ISA,
`a translation of the results of the earlier search into a language which is accepted bythe ISA,
`acopy of any document cited in the earlier search results (ifknown, please indicate belowthe documents availabie to the
`
`TSAy:ESA):
`
`Ci Request from the applicant te the receiving Office to transmit to the ISA a copy of the earher search results
`(Rule 125is.1(b) and (@)): Gvhere the earlier search was wot carried out by the ISA indicated in Box No. VU but by the same
`Office as that which is acting as receiving Office; or where the earlier search results are otherwise available to the receiving
`Office): the applicant requests the receiving Office to prepare and transmit to the ISA a copyof the earlier searchresults.
`* The applicant only needs to furnish a copyof the carlicr search results to the receiving Office, or the ISA, if none of the scenarios
`mentioned under item | applics. (See item 10 in the check-list and also Notes to Continuation ofBox Ne. VI, item 1).
`Cj
`Furtherearlier searches are indicated on a contimation sheet.
`2. Transmission of the earlier search and classification results to the FSA by the receiving Office where the applicant DID NOT
`make a request under Rule 4.12
`
`2.1 Where the international application claims priority of an earlier application, subject to Article 30(2\(a) and (3), the recenwing Office:
`- shall transmit a copyof the carlier search and classification results to the ISA (unless such copyis already available to the ISA),
`where the earlier application wasfiled with the same Office as that which is acting as the receiving Office and that Office has
`carried out the carlicr scarch in respect of the carlicr application (Rule 234is.2(a));
`- Inay transmit such a copyif the earlter application was filed with a different Office, but where the results of that earlier search
`aud classification arc nevertheless availabic to the receiving Office (Rule 23dis.2(c)).
`However, where the applicant did not requestthe receiving Office to transmitto the ISA a copyofthe earlier searchresultsunderRule 4.12
`(see above item 1), in respect of an earher search carried out on the following carlicr application, the priority of which is subsequently
`claimed in this international application, the applicant may consider (see aise Notes to Continuation ofBox No. VI, item 2; use ofmore
`than one earlier search):
`Filing date (day/month/year)
`
`Country for regional Office)
`
`Application Number
`
`to non-prejudicial disclosures or exceptions to lack of novelty
`
`Request not to transmit the earlier search results by the receiving Office to the ISA (Rule 23dis.2(b))
`Ina
`be checked where the international application is filed with the following receiving Offices: DE, Fi and SE)
`Authorization to transmit the earlier search and classification results by the receiving Officeto the ISA (Rule 235is5.2(a) and (e))
`to authorize the receiving Office to transmait the results of the earlier search and classification to the ISA (Rule 235is.2(¢)) (av
`onlybe checkedwhere the international application is filed with the jollowing receiving Offices: AU, CH, CZ, Fi, HU, IL, JP.
`NO, SE, SG and US)
`io authorize the receiving Office te tramsmit the results of the earlier international search and classification to the ISA
`(Rule 23bis.2(a) and Article 30(2)(a) and (GG) (may only be checked where the eurlier search concerns an international
`application, the priority of which is subsequently claimedin this international application and where the earlier international
`search was carried out by a different ISA than the ISA chosen in Box No. VT?)
`
`Box No. VEE @)
`Box No. VIE (ii)
`
`Box No. VF (ii)
`
`Box No. VIEE Gv)
`
`Box No. VIE (vy)
`
`Declaration as to the identity of the inventor
`Declaration as to the applicant’s ontitlcment, as at the intcrnational filing
`date, to apply for and be granted a patent
`Declaration as to the applicant's entitlement, as at the international filing
`date, to claim the priority of the carlicr application
`Declaration of inventorship (only for the purposes of the designationof the
`United States of America)
`Declaration as
`
`Form PCT/RO/LOL (third sheet) (Fuby 2017)
`
`See Notes to the request form
`
`Numberof
`declarations
`
`

`

`Box No. TX
`
`CHECK LIST for EPS-Web filings - this sheet is only to be used when filing an intemational application with ROVUS via EPS-Web
`
`This international application
`| contains the following:
`
`Number
`of sheets
`
`| (3) request form PCT/RO/101
`i
`(inchiding any declarations
`and supplemental sheets).......
`
`| (b) description (excluding any
`sequence listing part of the
`description, see (), below) ...
`
`claims .....0...00...0-.0....
`
`fy) abstract
`) drawings Gfany) .............
`
`i
`
`¢
`
`sequence listing part of the
`description in the form of an
`image fle (e.g PDF)..........
`
`Total number of sheets (including the
`i sequence listing part of the description
`| if filed as animage file). ...0...~«.
`
`:
`
`This international application is accompanied by the
`following item(s) (mark the applicable check-boxes below
`and indicate int right column the number ofeach item):
`1. BE fee catculation sheet 0.20
`
`Nurnber
`oftoms
`
`2.
`
`oviginal separate power ofattorney ................
`
`original general power of attorney©
`
`copy of general powerof attorney; reference
`MOMBE eee
`
`priority document(s) identified in Box No. Vi
`as ems)ee teens
`
`Translation of international application into
`(LANZUAZER tee eee
`
`separate indications concerning deposited
`microorganism or other biological material. .........
`
`fonly where item (f} is markedin the left column)
`copyofthe sequence listing in electronic form
`(Annex C/ST.25 text file) not forming part of
`the international applicationbut furnished only
`for the purposes of international search under
`Rule USfer 00 eee
`
`(2) sequence listing part of the description
`
`[I] filed in the form of an Anmex C/ST.25 text
`file
`
`Cl WILL BBfiled separately on physical data
`carrier(s), on the same day and in the form
`of an Annex C/ST.25 text file
`
`Indicate type and number of physical data
`carmier(S)0. ee
`
`fonly where item (f) (in the left column} and item 8 (above)
`are marked a statement confirming that “the information
`recorded in electronic form submitted under Rule [3 ter
`is identical to the sequence listing as contained in the
`international application”as filed via EFS-Web:......
`
`_{] copy of results of cartier search(es) (Rule 12dis. l(a) ..
`
`1, EF other (opecifl:. eee
`
`| Vigure of the drawings which
`i should accompanythe abstract:
`Box No. X
`SIGNATURE OF APPLICANT, AGENT OR COMMON REPRESENTATIVE
`| Next to each signature, indicate the nameofthe person signing and the capacity in which the person signs (ifsuch capacityis not obviousfrom reading the request).
`
`Language of filing of the
`international application:
`
`English
`
`| Attorney for Applicant
`
`| /Ryan D. Artis/
`i Ryan D. Artis, Reg. No. 67,798
`
`= For receiving OFFice US0 Orby eeceumeseszomeneozerees2enenzorneuenverenzooa2nzo0peooz7o2o70702020709 2020202020202 o2o008;
`
`
`Date of actual receipt of the purported
`Drawings:
`17 October 2019 (17.10.2019)|*:
`international application:
`
` rl received:
`
`Corrected date of actual receipt dueto later but
`timely reccived papers or drawings comploting
`the purportedinternational application:
`
`t| not received:
`Date of timely reecipt of the required
`corrections under PCTArticle 11(2):
`
`5. International Searching Authority
`Gf two or more are competent
`
`Date ofreceipt of the record copy
`f by the International Bureau:
`
`6.
`
`Transmittal of search copy delayed
`until search fee is paid
`ional Bureau use only
`
`Form PCT/RO/1G1 Cast sheet -- EFS) Guby 2017)
`
`See Notes to the requestform
`
`