Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`Amendments to the Claims
`
`This listing of claims will replace all prior versions, andlistings, of claims in the application:
`
`1-30.
`
`(Canceled)
`
`31.
`
`(New) A methodfor increasing apoptotic index, reducing adipose cells in number and/or
`
`volume, cellulite treatment, and/or circumferential reduction in a patient using a time-varying
`
`magnetic field, comprising:
`
`placing a magnetic field generating device proximate to a body region ofthe patient;
`
`charging an energy storage device;
`
`switching a switching device in order to discharge the energy storage device having a
`
`capacitance in a range of 5 nF to 100 mFto the magnetic field generating device having a total
`
`surface in a range of 5 to 8000 cm”in order to generate the time-varying magneticfield and
`
`generating the time-varying magnetic field with a winding magnetic fluence in a range of 40 to
`
`40000 T-cm?; and
`
`applying the time-varying magnetic field to the body region of abdomen between costae
`
`and iliac crest superior or pubic bone; or
`
`applying the time-varying magnetic field to the body region of a buttock between gluteal
`
`sulcus andiliac crest of the patient; or
`
`applying the time-varying magnetic field to the body region of thigh between gluteal
`
`sulcus and popliteal fossa of the patient;
`
`Page 2 of 21
`
`
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`Amendments to the Claims
`
`This listing of claims will replace all prior versions, andlistings, of claims in the application:
`
`1-30.
`
`(Canceled)
`
`31.
`
`(New) A methodfor increasing apoptotic index, reducing adipose cells in number and/or
`
`volume, cellulite treatment, and/or circumferential reduction in a patient using a time-varying
`
`magnetic field, comprising:
`
`placing a magnetic field generating device proximate to a body region ofthe patient;
`
`charging an energy storage device;
`
`switching a switching device in order to discharge the energy storage device having a
`
`capacitance in a range of 5 nF to 100 mFto the magnetic field generating device having a total
`
`surface in a range of 5 to 8000 cm”in order to generate the time-varying magneticfield and
`
`generating the time-varying magnetic field with a winding magnetic fluence in a range of 40 to
`
`40000 T-cm?; and
`
`applying the time-varying magnetic field to the body region of abdomen between costae
`
`and iliac crest superior or pubic bone; or
`
`applying the time-varying magnetic field to the body region of a buttock between gluteal
`
`sulcus andiliac crest of the patient; or
`
`applying the time-varying magnetic field to the body region of thigh between gluteal
`
`sulcus and popliteal fossa of the patient;
`
`Page 2 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`wherein the time-varying magnetic field is applied to a muscle and/or a nerve innervating
`
`the muscle in the body region with a treatment duty cycle of at least 1:50 and with a magnetic
`
`flux density sufficient to cause a muscle contraction of the muscle.
`
`32.
`
`(New) The method of claim 31 further comprising assembling subsequent magnetic
`
`pulses into a train lasting at least 25 ms.
`
`33.
`
`(New) The methodof claim 31 further comprising applying the time-varying magnetic
`
`field to the muscle and/or the nerve innervating the muscle in bursts, wherein each burst consists
`
`of first and second time periods; wherein thefirst time period consists of a plurality of
`
`subsequent magnetic pulses causing the muscle contraction of the muscle and wherein the
`
`muscle relaxes during the second time period.
`
`34.
`
`(New) The method of claim 31 further comprising applying at least 5000 pulses of the
`
`time-varying magnetic field to the body region.
`
`35.
`
`(New) The method of claim 34 further comprising generating the time-varying magnetic
`
`field with a maximal value of a magnetic flux density derivative in a range of 2 to 200 kT/s.
`
`36.
`
`(New) The method of claim 31 wherein the magnetic field generating device has a
`
`conductor diameter greater than 0 mm andless than 10 mm.
`
`Page 3 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`37.
`
`(New) The method of claim 36 wherein the magnetic field generating device has an
`
`inductance in a range of 1 nH to 1 H.
`
`38.
`
`(New) The method of claim 37 further comprising providing a current pulse ofat least
`
`250 A to the magnetic field generating device.
`
`39.
`
`(New) A methodfor increasing apoptotic index, reducing adipose cells in number and/or
`
`volume, cellulite treatment and/or a muscle toning, shaping or strengthening effect, a muscle
`
`volumeincrease using a time-varying magnetic field applied to a patient’s muscle comprising:
`
`placing a first applicator including a magnetic field generating device on a body region
`
`including a first muscle;
`
`placing a second applicator including a magnetic field generating device on a body region
`
`including a second muscle wherein the second muscle is a pair or cooperating muscle ofthe first
`
`muscle, and wherein the first magnetic field generating device is different from the second
`
`magnetic field generating device;
`
`providing energy to the magnetic field generating device having an inductance in a range
`
`of 1 nH to 1 Hin orderto generate the time-varying magnetic field with an impulse duration in a
`
`range of 3 to 3000 us; and
`
`applying the time-varying magnetic field to the patient’s muscle in the body region
`
`including at least one of thighs, saddlebags, buttocks, abdomen,hips, love handles, torso and/or
`
`armsof the patient in at least two bursts in order to cause a contraction of the patient’s muscle,
`
`wherein each said burst includesa train of a plurality subsequent pulses and wherein each said
`
`Page 4 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`burst lasts at least 10 ms and wherein the train causes the at least one contraction of the patient’s
`
`muscle and a relaxation follows after the contraction of the patient’s muscle.
`
`AO.
`
`(New) The method of claim 39 wherein a repetition rate of magnetic pulsesoffirst train
`
`differs from a repetition rate of magnetic pulses of secondtrain.
`
`Al.
`
`(New) The method of claim 39 further comprising applying the bursts to the patient with
`
`a burst duty cycle of at least 10 %.
`
`42.
`
`(New) The method of claim 39 further comprising relaxing the patient’s muscle after the
`
`contraction for a period lasting in a range of 1 to 15 seconds.
`
`43.
`
`(New) The method of claim 39 further comprising applying at least 25 bursts to the
`
`patient.
`
`44.
`
`(New) The methodof claim 39 further comprising generating the time-varying magnetic
`
`field with a winding magnetic fluencein a range of 40 to 40000 T-cm?.
`
`45.
`
`(New) The method of claim 39 wherein the magnetic field generating device include a
`
`core area and wherein the core area is in a range of 0.01 to 99 % ofa total surface of the
`
`magnetic field generating device.
`
`Page 5 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`46.
`
`(New) A method for providing a treatment increasing apoptotic index, reducing adipose
`
`cells, cellulite treatment and/or circumferential reduction using a time-varying magnetic field
`
`applied to a patient’s muscle comprising:
`
`placing an applicator including a magnetic field generating device in actual contact with a
`
`body region between rib-cage and popliteal fossa of a patient;
`
`attaching the applicator by a length adjustable positioning member;
`
`charging an energy storage device;
`
`switching a switching device;
`
`discharging the energy storage device to the magnetic field generating device in order to
`
`generate the time-varying magnetic field;
`
`applying the time-varying magnetic field with a magnetic flux density in a range of 0.1 to
`
`7 Tesla to the patient’s muscle within the body region and with a magnetic flux density at least
`
`sufficient to cause a muscle contraction of the patient’s muscle and/or a nerve innervating the
`
`patient’s muscle in order to cause a repetitive contraction of the patient’s muscle,
`
`assembling a plurality of magnetic pulses into a train lasting at least 10 ms wherein the
`
`train causes at least one contraction of the patient’s muscle and wherein the train is followed by a
`
`second time period when no contraction of the patient’s muscle is caused and wherein the second
`
`time period is longer than a duration of one magnetic pulsein the train.
`
`47.
`
`(New) The method of claim 46 further comprising applying the time-varying magnetic
`
`field to the patient with a treatment duty cycle of at least 10 %.
`
`Page 6 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`48.
`
`(New) The method of claim 47 further comprising applying 15 to 25000trains to the
`
`patient during one treatment.
`
`49.
`
`(New) The method of claim 46 further comprising applying to the patientat least first and
`
`secondtrain each having different repetition rate of the magnetic pulses.
`
`50.
`
`(New) The methodof claim 49 further comprising generating the time-varying magnetic
`
`field with a maximal value of a magnetic flux density derivative in a range of 300 T/s to 800
`
`kT/s.
`
`51.
`
`(New) The method of claim 46 further comprising applying a conventional treatment.
`
`52.
`
`(New) The method of claim 46 further comprising applying a conventional method to the
`
`patient no longer than 1 month before or after the treatment by time-varying magnetic field.
`
`53.|(New) A methodfor tissue treatment via a contraction of a muscle using a plurality of
`
`time-varying magnetic fields applied to a patient, comprising:
`
`placing a first applicator including a first magnetic field generating device to the patient;
`
`placing a second applicator including a second magnetic field generating device to the
`
`patient;
`
`mF;
`
`charging at least one energy storage device having a capacitance in a range of 5 nF to 100
`
`Page 7 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`switching at least one switching device in order to enable discharging the at least one
`
`energy storage deviceto the first and the second magnetic field generating devices wherein each
`
`magnetic field generating device has an inductance in a range of | nH to 1 H;
`
`generating a first time-varying magnetic field by the first magnetic field generating
`
`device and generating a second time-varying magnetic field by the second magnetic field
`
`generating device;
`
`assembling a plurality of impulses of the time-varying magnetic fields generated by the
`
`first and the second magnetic field generating devices into a plurality of magnetic pulses,
`
`wherein each impulse has a magnetic flux density in a range of 0.1 to 7 Tesla, a maximal
`
`value of a magnetic flux density derivative in a range of 300 T/s to 800 kT/s, a winding magnetic
`
`fluence in a range of 40 to 40000 T-cm?, and
`
`wherein each magnetic pulse consists of one impulse of the time-varying magnetic field
`
`lasting for an impulse duration and no magnetic field lasting fora first time period;
`
`establishing a burst consisting of a second time period and a third time period, wherein
`
`the plurality of magnetic pulses is generated during the second time period and wherein the third
`
`time period follows after the second time period;
`
`applying the bursts to a body region ofthe patient including at least one of thigh,
`
`saddlebags, buttock, abdomen,hips, love handle, flanks, bra fat region, torso and/or arm of the
`
`patient with a repetition rate in a range of 1 to 700 Hz and with the impulse duration in a range of
`
`10 to 3000 us;
`
`applying at least 5000 magnetic pulses to the body region;
`
`causing the contraction of the muscle during the second time period; and
`
`causing no contraction of the muscle during the third time period.
`
`Page 8 of 21
`
`
`
`Response to Non-Final Office Action dated October 1, 2018
`Attorney Docket No. 206265-0006-01-US.607727
`Application No. 16/034,793
`
`54.
`
`(New) The method of claim 53 wherein the third time period lasts up to 20 seconds.
`
`55,
`
`(New) The method of claim 54 further comprising generating the first and/or the second
`
`time-varying magnetic field with a treatment duty cycle ofat least 10 %.
`
`56.
`
`(New) The method of claim 55 further comprising applying to the muscle of the patient
`
`40 to 10000 bursts within one treatment.
`
`57.
`
`(New) The method of claim 53 wherein the second time period lasts up to 15 seconds.
`
`58.
`
`(New) The method of claim 53 further comprising generating at least ten magnetic
`
`impulses during the second time period.
`
`59,
`
`(New) The method of claim 53 further comprising generating at least two bursts each
`
`having different repetition rate of the magnetic pulses.
`
`60.
`
`(New) The method of claim 53 further comprising attaching the first and the second
`
`applicators to the patient by at least one length adjustable positioning member.
`
`Page 9 of 21
`
`
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