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`SE 10—-506409
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`SE 10—-506409
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`
`SE 10—-506409
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`TERA ACHR5 AT HEN TVS 0
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`SE 10—-506409
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`SE 10—-506409
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`—ORBICR Lio RVC, Hl LIAMED E SK Lb 2 ODER LEE
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`SE 10—-506409
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`Fit
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`HE
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`(mg)
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`fa nk yO BE %
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`ffi7K USP/EP *
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`218.500
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`87.4
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`5.000
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`0.75 0
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`9.000
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`1.250
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`250.000
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`SE 10—-506409
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`Apfel, O. SRE. O.7 SARI, LR, 1. OFF, QR, 2. ORF3
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`781 Omg (2x SmgseAly5%4) ELTRELI.
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`SE 10—-506409
`
`
`pave||
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`104.85
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`
`SE 10—-506409
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`SE 10—-506409
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`
`RM 4 5756 27R CORR 1ARBMChETYIA-LEF + avy
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`
`SE 10—-506409
`
`
`CHBS NGAP Hc LPS, MMPEMLEM LIL Ra, KLVUY
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`Hahete 7.0 4m g tc UUFERREMOR Chl € 17e, LichoT,
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`mg (GF) ABOMAD SDL LY YOEAKARWRIL, FO 1DORA (
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`(23)
`
`SE 10—-506409
`
`KOBE PRYAFYA—-UBMBAEO HV BSCEE a TW ST LERL
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`BE. SHP1 C1 Omg (MER) GSU(2.9 6meglFEH)
`
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`
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`SzHEPA 4
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`
`
`(24)
`
`SE 10—-506409
`
`ak
`
`4}
`
`HE
`
`(mg)
`
`AA AR AP OE %
`
`fi 7. USP/EP
`
`221.625
`
`88.65
`
`EVL) y Heme
`
`+25 FY EP/USNF
`
`5.000
`
`11.250
`
`vis hb EP/USP
`
`8.125
`
`F ARM F— A EP/USNE
`
`1.250
`
`FY-FPRHY IE
`
`502.106/A
`
`7 = RB EP/USP
`
`AARNF vb AD-22901
`
`0.750
`
`1.250
`
`2.00
`
`4.50
`
`3.25
`
`0.50
`
`0.30
`
`0.50
`
`Ana —
`
`0.750
`
`0.30
`
`at
`
`250.000
`
`100.00
`
`KiL, RMR Poe AP RELA LEK BRS,
`
`Seip 5
`
`ie
`
`at
`
`BE (mg)
`
`a BK eH EE Be %
`
`@i 7k USP/EP *
`
`224.125
`
`89.65
`
`ee Y YY tee
`
`> FY EP/USNF
`
`vUws ba 7b EP/USP
`
`Pye PANH VFL oes
`
`502.10 6/A
`
`4 =. YE EP/USP
`
`AeaAF Yb AD-22901
`
`5.000
`
`9.375
`
`7.500
`
`0.750
`
`1.250
`
`2.00
`
`3.7 5
`
`3.00
`
`0.30
`
`0.50
`
`Ana
`
`PwANF ea—AK
`
`0.750
`
`1.250
`
`0.30
`
`0.50
`
`Ht
`
`250.000
`
`100.00
`
`kik, PRIS oe AIRE LE LER RRTSA,
`
`
`
`(25)
`
`SE 10—-506409
`
`Sebi 6
`
`a7
`
`4}
`
`He (mg)
`
`AE KH Be %
`
`li 7k USP/EP *
`
`219.500
`
`87.80
`
`EUV IY eee
`
`5.000
`
`2 > F vy EP/USNF
`
`10.000
`
`v= h—/- EP/USP
`
`7.500
`
`Y AR WF —bd EP/USNE
`
`1.000
`
`FY Y vy USP
`
`2 =. HE EP/USP
`
`tAFYb AD-22901
`
`2.500
`
`1.250
`
`4a
`
`0.750
`
`veEvoa&5 9.1 5 /AP
`
`2.500
`
`2.00
`
`4.00
`
`3.00
`
`0.40
`
`1.00
`
`0.50
`
`0.30
`
`1.00
`
`3+
`
`250.000
`
`100.00
`
`IL, AG RRT PE ZPKRAELEL ER BRT S,
`
`Seip 7
`eRUmgl)EP©
`
`fall 7k USP/EP *
`
`223.625
`
`89.45
`
`weY Uy ieee
`
`5.000
`
`> FY EP/USNF
`
`10.000
`
`2.00
`
`4.00
`
`
`
`(26)
`
`SE 10—-506409
`
`vy = f— 7) EP/USP
`
`7.5900
`
`Y ACSW F — 2 EP/USNF
`
`0.750
`
`PU-PFFN-VY PVA
`
`502.10 6/4
`
`7 oo WR EP/USP
`
`ANF Y b AD-22901
`
`0.750
`
`1.250
`
`3.00
`
`0.30
`
`0.3 0
`
`0.50
`
`{zu
`
`0.750
`
`0.3 0
`
`FRU VUAAF MAD SY EP/USNF
`
`0.25 0
`
`0.10
`
`PRU DAA RE MAF SY EP/USNF
`
`0.125
`
`Q.05
`
`zu
`it
`
`250,000
`
`100.00
`
`Kit, RB oe AI RELELERRRT SA,
`
`El 8
`
`Fk
`
`oy
`
`Be
`
`(mg)
`
`AB Ke 4 PD Ee Et %
`
`it 7k USP/EP *
`
`219.125
`
`87.65
`
`wey Uy ime ie
`
`5.000
`
`29 FY EP/USNF
`
`10.625
`
`vy h/t EP/USP
`
`6.875
`
`F AS WF — ds EP/USNF
`
`1.250
`
`FV YY USP
`
`5.000
`
`Fy—-LFeN- YAY
`
`502.10 6/A
`
`7 =. # EP/USP
`
`0.750
`
`0.625
`
`2.00
`
`4.25
`
`2.75
`
`0.50
`
`2.00
`
`0.30
`
`0.25
`
`
`
`(27)
`
`SE 10—-506409
`
`ANF i & AD-22901
`
`f{ =-a—
`
`0.75 0
`
`0.3 0
`
`at
`
`250.000
`
`100.00
`
`
`KIL, GRP oe API RRAELAE LER BRS S,
`
`Seite9
`
`BK
`
`ay
`
`Hs (mg)
`
`A A PD Ht %
`
`ii 7k USP/EP *
`
`216.750
`
`86.7
`
`EY Uy wee
`
`5.000
`
`2 > FY EP/USNF
`
`10.000
`
`vivo kh — 7 EP/USP
`
`7.500
`
`Y ARIF — Js EP/USNF
`
`1.250
`
`ZY yy USP
`
`3 =x. WR EP/USP
`
`AAFY & AD-22901
`
`4mna—
`
`FRAVIS =—AK
`
`3.750
`
`1.250
`
`0.750
`
`1.250
`
`vEYSAAS 9.1 5 /AP
`
`2.500
`
`2.0
`
`4.0
`
`3.0
`
`0.5
`
`1.5
`
`0.5
`
`0.3
`
`0.5
`
`1.0
`
`et
`
`250.000
`
`100.0
`
`Kil, RP RTO APIRERELE LER BRT S,
`
`Site1O
`ik
`43
`Be (mg)
`A Ke HH>
`
`* fil zk USP/EP
`
`EP nV Vy
`
`215.875
`
`12.000
`
`86.35
`
`4.80
`
`
`
`(28)
`
`SE 10—-506409
`
`> FY EP/USNF
`
`10.000
`
`Y= hb EP/USP
`
`8.125
`
`YT APSF — Ld EP/USNF
`
`1.250
`
`FYyv-PIMAHVYIVOHN
`
`502.16 6/A
`
`0.750
`
`FY vy USP
`
`-
`
`1.250
`
`aeNF Yb AD-22901
`
`4.00
`
`3.2 5
`
`0.5 0
`
`0.30
`
`0.50
`
`fxaa—
`
`0.750
`
`0.30
`
`#t
`
`250.000
`
`100.00
`
`KUL, RRR oe APICRAELE ILS BRA,
`
`Seep1 1
`
`mk
`
`val
`
`He (mg)
`
`KA pk Yh OD Ee Et %
`
`fai 7k EP/USP*
`
`FPADRE
`
`797.500
`
`100.000
`
`25 FY EP/USNF
`
`45.000
`
`7 = bh J EP/USP
`
`35.000
`
`LEY G4 A 59.15/AP
`
`5.000
`
`FY YY USP
`
`10.000
`
`Y ALSF — J EP/USP
`
`7.500
`
`79.75
`
`10.00
`
`4.50
`
`3.50
`
`0.50
`
`1.00
`
`0.75
`
`at
`
`1000.000
`
`100.00
`
`Ki, TERROR PO eR APICRRLETELRBR TA,
`
`
`
`(29)
`
`SE 10—-506409
`
`(Hi 1)
`
`ALGMELee
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`
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`CU)idea
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`
`SE 10—-506409
`
`1(ge
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`SE 10—-506409
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`SE 10—-506409
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`
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`
`SE 10—-506409
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`(4)Gaga
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`
`SE 10—-506409
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`(H6)
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`
`SE 10—-506409
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`i
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`
`SE 10—-506409
`
`
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`Clk 1 5 BORE) FP SY AEY A-BAT VEER MLE UERA
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`RICKIT LACMENGE SD CHMAISN TWIST LARA L TS SHROR
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`CHRENSAMCHIT. KH, XAVKRRTERIAFVBERL. YAN
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`
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`
`RBCS SaPROMAE 1 A~ 3 ROWSAICAMOMKH
`
`5 Wade 7 SYAFY A-BAT YER R—APARA :
`
`
`
`(37)
`
`SE 10—-506409
`
`(1)
`
`x|
`
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`CHs
`
`CRENS(LGMWCH oT. AH, XBKOY DPRORAR 4 ICES SNT
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`
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`
`
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`
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`
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`SURE 6 I~ 8 ROWSHAC AMOMKM.
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`
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`
`KAY 5 7k SIRO SURGESAE OBRCH OT. BE UVMRE
`
`TNC CANEE CHO Ei, MRKADEAKORMD SARAT
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`
`
`
`(38)
`
`SE 10—-506409
`
`ARE LICIBI ED SRRENTWS4TLRRALT ZARORAS 1 OIC
`
`OR
`
`12 Wfaceaton’, OREICANT LEW 1 OMLANICHHT 4c Le
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`
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`
`BUELYU YE, By UVR IAMR LICARED SMRENTWSTE
`
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`
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`
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`
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`15 WEY Y YROI T Se DORROBAOWSTAD 1
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`
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`PBS KO/E KSPR RROMECEATSTL.
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`
`17 BPROSUAS 1 TALE 1 4BOWTHDCHRLEMRET IVY IN
`
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`
`18 AA BI STI LAV LFV?S 3 YOVUNVE RDS EOD ERORED
`
`COCMROGME 1 ACO1 4ROWPTHDcLEMKE EAT S
`
`Fitko
`
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`
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`
`THA AR L 7cRe BET SA.
`
`
`
`(39)
`
`SE 10—-506409
`
`ational Applicaton No
`PCT/GB 96/00484
`
`Form PCTJISA/2L0 fsecond sheet) (July 1993} Patent family members are listed jn annex.
`
`“T" later documentpublished after the mtematonal filing date
`or Brority date and not in conflict with the application but
`cited to unckrstand the pnocple or theory undertying the
`inventon
`’ dgcument of particular relevance, the claimed invention
`Sannot b¢ considered novel of cannot be considered to
`involve an invenove step when the document is taken alone
`" document of particular relevance, the claimed invention
`cannot be considered to involve an invenbve step when the
`document is combined with one or more other such docu
`ments, such combinaton being obvious to a person skilled
`in the aru
`, document member of the same patent family
`Date of mailing of the intemauonal search report
`2 1.06. 96
`
`CE RRaaR]
`
`INTERNATIONAL SEARCH REPORT
`
`A.
`]
`
`TTER
`CLASSIFICATION OF SUBIECT MA
`PC 6
`=©AG1K31/135
`AG1K9/08
`
`AGLK31/40
`
`AG1K31/44
`
`According to Intemational Patent Classification (IPC) or to both matenal clasaficaguon and LPC
`B, FIELDS SEARCHED
`Minimum documentagen searched (classification system followed by clatsification symbols}
`IPC 6
`A61K
`
`Documentation searched other than minimum docurneatauonto the extent that such

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