Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`Substitute for form 1449/PTO
`_
`
`Complete if Known
`
`Application Number
`
`15933944
`
`
`
`Examiner
`lnitials*
`
`D
`
`ocumen
`
`t N
`
`b
`um er
`
`Publication Date
`MM-DD-YYYY
`
`Name of Patentee or
`Applicant of Cited Document
`
`Pages, Columns, Lines, Where
`Relevant Passages or Relevant
`Figures Appear
`
`U. S. PATENT DOCUMENTS
`
`Number-Kind Codez (”km")
`
`US-7465790
`
`12-16-2008
`
`WALDMANN; Herman et al.
`
`US-8709755
`
`04-29-2014
`
`SHORT; Jay M. et al.
`
`US-8859467
`
`10-14-2014
`
`SHORT; Jay Milton
`
`US-9683985
`US-20100260739
`
`06-20-2017
`10-14-2010
`
`:IODANDAPANI; Lalltha et
`SHORT; Jay M. et al.
`
`US-20130028893
`
`01-31-2013
`
`WALDMANN; Herman et al.
`
`US-20130315906
`
`11-28-2013
`
`LOWMAN; Henry Bernard et
`
`US-20150024944
`
`01-22-2015
`
`SHORT; Jay Milton
`
`US-20160129131
`US-20160144042
`
`05-12-2016
`05-26-2016
`
`XIITARI; Alberto Clemente et
`WILLIAMS; John C. et al.
`
`US-20160228546
`
`08-11-2016
`
`STAGL'ANO? Nancy
`Elizabeth et al.
`
`
`
`US-20170191055
`
`07-06-2017
`
`SHORT; Jay M. et al.
`
`Examiner
`Signature
`
`Date
`Considered
`
`1
`2
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not
`4
`considered. Include copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
`5
`Documents at wwwusgtogov or MPEP 901.04. 3 Enter Office that issued the document, by the two-letter code (WIPO Standard ST.3). For Japanese patent documents, the
`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. 6Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
`governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering, preparing, and submitting the completed application
`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
`burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`
`
`
`INFORMATION DISCLOSURE —°ciffl4p§%1tst Da .0,
`STATEMENT BY APPLICANT
`MU,“
`1534
`(Use as many sheets as necessary)
`Not yet assigned
`Attorney Docket Number
`52426—701 201
`
`;
`
`VI
`
`.—
`
`

`

`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`SubstItute for form 1449/PTO
`_
`
`Complete if Known
`
`Application Number
`
`15933944
`
`INFORMATION DISCLOSURE —°ciin4p§%18t Da .d
`
`;
`
`Vl
`
`STATEMENT BY APPL'CANT
`(Use as many sheets as necessary)
`
` 03
`
`
`
`
`Attorney Docket Number
`
`Not ye} assigned
`
`Examiner
`lnitials*
`
`.
`
`Foreign Patent Document
`
`Publication
`Date
`MM-DD-YYYY
`
`Name of Patentee or
`Applicant of Cited Document
`
`Pages, Columns, Lines,
`Where Relevant Passages
`Or Relevant Figures Appear
`
`Country CodeaTNumberATKind Code5 (if known)
`
`FOREIGN PATENT DOCUMENTS
`
`WO-2012033953-A1
`
`WO-2014193973-A2
`
`WO-2016004383-A1
`
`03-15-2012 HALOZYME 'NC
`[US], et al.
`
`12-04-2014
`
`DCB USA LLC
`[US], et al_
`
`01-07-2016
`
`HOPE CITY [US],
`et al.
`
`WO-2016011210-A2
`
`01-21-2016
`
`JUNO
`THERAPEUTICS
`
`INC [US]
`
`WO-2016036916-A1
`
`03-10-2016
`
`BIOATLA LLC [US]
`
`WO-2016138071-A1
`
`09-01-2016
`
`SHORT JAY M
`[US], et al.
`
`WO-2016179003-A1
`
`11-10-2016
`
`EJESTENTECH 'NC
`
`WO-2016200645-A1
`
`12-15-2016
`
`WANG TIANXIN
`[US]
`
`WO-2017034615-A1
`
`03-02-2017
`
`BIOATLA LLC [US]
`
`WO-2017075537-A1
`
`05-04-2017
`
`ALETA
`BIOTHERAPEUTI
`
`Examiner
`Signature
`
`cs lNC [US]
`
`Date
`Considered
`
`*EXAMINER: lnitial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not
`considered lnclude copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
`Documents at www. usgto.gov or MPEP 901. 04. Enter Office that issued the document, by the two- letter code (WIPO Standard ST.3). For Japanese patent documents, the
`
`indication of the year of the reign of the Emperoremust precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WlPO Standard ST.16 if possible. Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
`governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering, preparing, and submitting the completed application
`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
`burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`
`

`

`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`Substitute for form 1449/PTO
`_
`
`Complete if Known
`
`Application Number
`
`15933944
`
`INFORMATION DISCLOSURE —giffl4pg‘;1L8L Da .0,
`
`;
`
`Vl
`
`STATEMENT BY APPL'CANT
`(Use as many sheets as necessary)
`
`
`
`Attorney Docket Number
`
`Not ye} assigned
`
`Examiner
`Initials*
`
`'
`.
`
`
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journal,seria|,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`GRANT et al. Matrigel induces thymosin h 4 gene in differentiating endothelial cells. J Cell Sci
`108:3685-3694 (1995).
`
`LE GALL et al. lmmunosuppressive properties of anti-CD3 single-chain Fv and diabody. J
`Immunol Methods 285(1):111-127 (2004).
`
`MURTAUGH et al. A combinatorial histidine scanning library approach to engineer highly pH-
`dependent protein switches. Protein Sci 20(9):1619-1631 (2011).
`
`TAKEUCHI et al. Roles ofthe histidine and tryptophan side chains in the M2 proton channel
`from influenza A virus. FEBS Lett 552(1):35-38 (2003).
`
`Examiner
`Signature
`
`Date
`Considered
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1-800-786-9199} and select option 2.
`
`