Receipt: date: 11/26/2019
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`INFORMATION DISCLOSURE —;‘;;g§mmiam
`STATEMENT BY APPLICANT _1639 ’
`(Use as many sheets as necessary)
`_Kaijiang Zhang
`Attorney Docket Number
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`US-5688642
`
`US-5854033
`
`US-6287824
`
`US-6408308
`
`US-6728129
`
`US-8500979
`
`US-9925510
`
`US-20040219663
`
`US-20050112679
`
`US-20060160138
`
`US-20100099103
`
`US-20120032366
`
`US-20120164127
`
`US-20120164633
`
`US-20130005585
`
`US-20130164308
`US-20150099870
`
`US-20150293102
`
`US-20160019341
`
`US-20160289758
`
`06-27-2013
`
`CHRISEY; Linda A. etal.
`
`LIZARDI; Paul M.
`
`LIZARDI; Paul M.
`
`MASLYN;Timothy J. et aI.
`
`LINDSEY; Jonathan S. et aI.
`
`ELIBOL; Oguz H. et aI.
`
`JACOBSON; Joseph et aI.
`
`PAGE; Robert D. etal.
`
`MYERSON;JoeIetaI.
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`CHURCH; George
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`HSIEH; Chung-Ming etal.
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`IVNISKI; Dmitri et aI.
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`SHORT; Jay M. et aI.
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`LAFFLER; Thomas
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`ANDERSON; Megan et aI.
`
`EIOLETT'; Dav'de Luc'ano et
`BENNETT; Clay etal.
`
`SHIM;Jung-Uk
`
`HARRIS; Jason et aI.
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`AKESON; Mark A. etal.
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`US-20170066844
`
`GLANVILLE; Jacob
`
`Examiner
`
`Signature
`
`/KAIJIANG ZHANG/
`
`Date
`
`Considered
`
`91/30/2920
`
`1
`2
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not
`4
`considered. Include copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
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`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. 6Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
`governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering, preparing, and submitting the completed application
`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
`burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1-800-786-9199} and select option 2.
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`Receipt: date: 11/26/2019
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`Approved for use through 11/30/2020. OMB 0651-0031
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`Substitute for form 1449/PTO
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`—15729564
`INFORMATION DISCLOSURE —;‘;;g§mmiam
`STATEMENT BY APPLICANT _1539 ’
`(Use as many sheets as necessary)
`_Kaijiang Zhang
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`US-20170175110
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`US-20170249345
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`US-20170253644
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`EVANS; Eric Andrew et al.
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`CEZE; Luis Henrique et al.
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`BANYAI; William et al.
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`US-20190060345
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`02-28-2019
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`HARRISON; Nancy et aI.
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`US-20190118154
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`04-25-2019
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`EUGENE; P. Marsh et aI.
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`US-20190240636
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`08-08-2019
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`PECK; Bill James et aI.
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`Pages, Columns, Lines, Where
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`Examiner
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`EP-1363125-A2
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`WO-02072791-A2
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`11-19-2003
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`GENTEL CORP
`[US]
`
`09-19-2002
`
`UNIV MICHIGAN
`[US], et al_
`
`WO-2006023144
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`03-02-2006 BIOREN INC.
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`WO-2008045380
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`04-17-2008
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`CODON DEVICES,
`INC.
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`Examiner
`
`Date
`
`[KAIJIANG ZHANG/
`
`01/30/2020
`
`1
`2
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not
`4
`considered. Include copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
`5
`Documents at yywyguggtgflgyflor MPEP 901.04. 3 Enter Office that issued the document, by the two-letter code (WIPO Standard ST.3). For Japanese patent documents, the
`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. 6Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
`governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering, preparing, and submitting the completed application
`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
`burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
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`

`Receipt: date: 11/26/2019
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`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
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`SubstItute for form 1449/PTO
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`INFORMATION DISCLOSURE —;‘;;g§mmiam
`STATEMENT BY APPLICANT _1539 ’
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`_Kaijiang Zhang
`Attorney Docket Number
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`FOREIGN PATENT DOCUMENTS
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`Foreign Patent Document
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`Date
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`Country Codea’NumberA’Kind Code5 (if known)
`
`WO-2008063134-A1
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`05-29-2008
`
`WO-2014008447-A1
`
`01-09-2014
`
`
`
`Name of Patentee or
`Applicant of Cited Document
`
`Pages, Columns, Lines,
`Where Relevant Passages
`Or Relevant Figures Appear
`
`AGENCY
`SCIENCE TECH &
`
`RES [SG], et al.
`INTEGRATED
`DNA TECH INC
`
`XENCO MEDICAL
`LLC [US]
`
`'NV'TAE CORP
`
`
`
`WO-2015081142-A1
`
`WO-2016055956-A1
`
`WO-2016161244-A2
`
`06-04-2015
`
`04-14-2016
`
`SCRIPPS
`10-06-2016 RESEARCH INST
`
`WO-2016173719-A1
`
`11-03-2016
`
`ABCHECK S R O
`[CZ], et al_
`
`
`
`Examiner
`Signature
`
`[KAI JIANG ZHANG/
`
`D 1 i 3 O / 2 O 2 O
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`Date
`Considered
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`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not
`considered Include copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
`Documents at www. uspto.gov or MPEP 901. 04. Enter Office that issued the document by the two- letter code (WIPO Standard ST.3). For Japanese patent documents, the
`6
`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
`governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering, preparing, and submitting the completed application
`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
`burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800-PTO-9199 (1---800 786-9199} and select option 2.
`ALL REFERENCES CONSIDERED EXCEPT WERE LINED THROUGH [R Z/
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`

`

`Receipt: date: 11/26/2019
`
`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`_
`Substitute for form 1449/PTO
`
`Complete if Known
`
`—15729564
`INFORMATION DISCLOSURE —;%i$§iiix7vnuam
`STATEMENT BY APPLICANT _1539 ’
`(Use as many sheets as necessary)
`_Kaijiang Zhang
`Attorney Docket Number
`A 4854-701 _309
`
`
`
`
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`N
`
`_I
`
`Assembly manual for the POSaM: THE ISB Piezoelelctric Oligonucleotide Synthesizer and
`Microarrayer, The Institute for Systems Biology, May 28, 2004 (50 pages).
`
`DOUTHWAITE et al.: Affinity maturation of a novel antagonistic human monoclonal antibody
`with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1; mAbs, vol. 7, Iss.
`1, pp. 152-166 (01Jan2015).
`
`EROSHENKO et al.: Gene Assembly from Chip-Synthesized Oligonucleotides; Current
`Protocols in Chemical biology 4: 1-17 (2012).
`
`European Patent Application No. 148346653 Further Examination Report dated November 28,
`2018.
`
`European Patent Application No. 16847497.1 Extended European Search Report dated
`January 9,2019.
`
`European Patent Application No. 16871446.? European Search Report dated April 10, 2019.
`
`GALKA et al.: QuickLib, a method for building fully synthetic plasmid libraries by seamless
`cloning of degenerate oligonucleotides. PLOS ONE, 12, e0175146:1-9 (2017).
`
`GALKA et al.: QuickLib, a method for building fully synthetic plasmid libraries by seamless
`cloning of degenerate oligonucleotides. PLOS ONE, 12, e0175146:S1 figure (2017).
`
`GALKA et al.: QuickLib, a method for building fully synthetic plasmid libraries by seamless
`cloning of degenerate oligonucleotides. PLOS ONE, 12, e0175146:S1 Table (2017).
`
`GALKA et al.: QuickLib, a method for building fully synthetic plasmid libraries by seamless
`cloning of degenerate oligonucleotides. PLOS ONE, 12, e0175146:SZ figure (2017).
`
`Examiner
`
`Date
`
`[KAIJIANG ZHANG/
`
`01/30/2020
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`ALL REFERENCES CONS IDERED EXCEPT WERE LINED THROUGH .
`[K . Z/
`
`

`

`Receipt: date: 11/26/2019
`
`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`_
`Substitute for form 1449/PTO
`
`Complete if Known
`
`—15729564
`INFORMATION DISCLOSURE —;%i$§iiix7vnuam
`STATEMENT BY APPLICANT _1539 ’
`(Use as many sheets as necessary)
`_Kaijiang Zhang
`Attorney Docket Number
`A 4854-701 _309
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`N
`
`_I
`
`
`
`
`
`International Application No. PCT/USZO17/026232 International Preliminary Report on
`Patentability dated February 26, 2019.
`
`International Application No. PCT/USZO17/O45105 International Preliminary Report on
`Patentability dated February 5, 2019.
`
`International Application No. PCT/USZO17/O52305 International Preliminary Report on
`Patentability dated April 30, 2019.
`
`International Application No. PCT/USZO17/O62391 International Preliminary Report on
`Patentability dated May 21 , 2019.
`
`International Application No. PCT/USZO18/019268 International Preliminary Report on
`Patentability dated September 6, 2019.
`
`International Application No. PCT/USZO18/O50511 International Search Report and Written
`Opinion dated January 11, 2019.
`
`International Application No. PCT/USZO18/057857 International Search Report and Written
`Opinion dated March 18,2019.
`
`International Application No. PCT/USZO19/O12218 International Search Report and Written
`Opinion dated March 21,2019.
`
`International Application No. PCT/USZO19/O32992 International Search Report and Written
`Opinion dated October 28, 2019.
`
`International Application No. PCT/USZO19/O32992 Invitation to Pay Additional Fees dated
`September 6,2019.
`
`Examiner
`Signature
`
`/KAI JIANG ZEANG/
`
`Date
`Considered
`
`O 1 / 3D / 2 02 Q
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`ALL REFERENCES CONS IDERED EXCEPT WERE LINED THROUGH .
`[K . Z/
`
`

`

`Receipt: date: 11/26/2019
`
`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`_
`Substitute for form 1449/PTO
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`Complete if Known
`
`—15729564
`
`I
`(Use as many sheets as necessary)
`
`a
`I
`Art Unit
`
`e
`
`nven or —‘ ‘illl
`1639
`
`—Kaiiian9 Zhang
`Attorney Docket Number
`A 4854-701 _309
`
`Examiner
`Initials*
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`N
`
`_I
`
`
`
` NON-PATENT LITERATURE DOCUMENTS
`
`JO et al.: Engineering therapeutic antibodies targeting G-protein-coupled receptors;
`Experimental & Molecular Medicine; 48; 9 pages (2016).
`
`Lausted et al.: POSaM: a fast, flexible, open-source, inkjet oligonucleotide synthesizer and
`microarrayer; Genome Biology 2004, 5:R58.
`
`MARTINEZ-TORRECUADRADAet al.: Targeting the Extracellular Domain of Fibroblast Growth
`Factor Receptor 3 with Human Single-Chain Fv Antibodies Inhibits Bladder Carcinoma Cell Line
`Proliferation; Clinical Cancer Research; vol. 11; pp. 6282-6290 (2005).
`
`MAZOR et al.: Isolation of Full-Length IgG Antibodies from Combinatorial Libraries Expressed in
`Escherichia coli; Antony S. Dimitrov (ed.), Therapeutic Antibodies: Methods and Protocols, vol.
`525, Chapter 11, pages 217-239 (2009).
`
`PCT/USZO18/O37161 International Search Report and Written Opinion dated October 22, 2018.
`
`PCT/USZO18/056783 International Search Report and Written Opinion ofthe International
`Searching Authority dated December 20, 2018.
`
`US. Patent Application No. 15/015,059 Final Office Action dated July 17, 2019.
`
`US. Patent Application No. 15/015,059 Office Action dated August 19, 2019.
`
`US. Patent Application No. 15/015,059 Office Action dated February 7, 2019.
`
`US. Patent Application No. 15/151,316 Office Action dated October 4,2019.
`
`US. Patent Application No. 15/151,316 Final Office Action dated February 21,2019.
`
`US. Patent Application No. 15/156,134 Office Action dated April 4, 2019.
`
`Examiner
`Signature
`
`[IKE-XI JIANG- ZHANG/
`
`Date
`Considered
`
`CI 1 ,I’ 30 [2 02 O
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1-800-786-9199} and select option 2.
`ALL REFERENCES CONS IDERED EXCEPT WERE LINED THROUGH .
`[K . Z/
`
`

`

`Receipt: date: 11/26/2019
`
`Approved for use through 11/30/2020. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`_
`Substitute for form 1449/PTO
`
`Complete if Known
`
`—15729564
`INFORMATION DISCLOSURE —;%i$§iiix7vnuam
`STATEMENT BY APPLICANT _1539 ’
`(Use as many sheets as necessary)
`_Kaijiang Zhang
`Attorney Docket Number
`A 4854-701 _309
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`_|
`
`
`
`
`
`US. Patent Application No. 15/187,714 Final Office Action dated September 17, 2019.
`
`US. Patent Application No. 15/187,714 Office Action dated April 4, 2019.
`
`US. Patent Application No. 15/268,422 Final Office Action dated October 3, 2019.
`
`US. Patent Application No. 15/268,422 Office Action dated March 1, 2019.
`
`US. Patent Application No. 15/377,547 Final Office Action dated February 8, 2019.
`
`US. Patent Application No. 15/433,909 Non-Final Office Action dated February 8, 2019.
`
`US. Patent Application No. 15/602,991 Final Office Action dated December 13, 2018.
`
`US. Patent Application No. 15/602,991 Office Action dated May 31, 2019.
`
`US. Patent Application No. 15/603,013 Final Office Action dated November 6, 2019.
`
`US. Patent Application No. 15/619,322 Office Action dated August 14, 2019.
`
`US. Patent Application No. 15/709,274 Notice of Allowance dated April 3, 2019.
`
`US. Patent Application No. 15/729,564 Final Office Action dated December 13, 2018.
`
`US. Patent Application No. 15/816,995 Office Action dated September 20, 2019.
`
`US. Patent Application No. 15/816,995 Restriction Requirement dated April 4, 2019.
`
`US. Patent Application No. 15/835,243 Restriction Requirement dated September 10, 2019.
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`INFORMATION DISCLOSURE —;%i$§iiix7vnuam
`STATEMENT BY APPLICANT _1539 ’
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`_Kaijiang Zhang
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`NON-PATENT LITERATURE DOCUMENTS
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`US. Patent Application No. 15/844,395 Restriction Requirement dated May 17, 2019.
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`US. Patent Application No. 15/860,445 Final Office Action dated December 13, 2018.
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`US. Patent Application No. 15/921 ,479 Office Action dated November 12, 2019.
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`US. Patent Application No. 15/921,479 Restriction Requirement dated May 24, 2019.
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`US. Patent Application No. 15/960,319 Office Action dated August 16, 2019.
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`US. Patent Application No. 16/006,581 Office Action dated September 25, 2019.
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`US. Patent Application No. 16/239,453 Office Action dated November 7, 2019.
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`US. Patent Application No. 16/409,608 Office Action dated September 9, 2019.
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`US. Patent Application No. 16/530,717 Office Action dated September 6, 2019.
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`US. Patent Application No.15/603,013 Office Action dated June 26, 2019.
`
`WU, et al. "Sequence-Specific Capture of Protein-DNA Complexes for Mass Spectrometric
`Protein Identification" PLoS ONE. 20 October 2011, Vol. 6, No. 10.
`
`ZHOU, et al. "Establishment and application ofa loop-mediated isothermal amplification (LAMP)
`system for detection of cry1Ac transgenic sugarcane" Scientific Reports 09 May 2014, Vol. 4,
`No. 4912.
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`Examiner
`
`Date
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`[KAIJIANG ZHANG/
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`01/30/2020
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`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1-800-786-9199} and select option 2.
`ALL REFERENCES CONS IDERED EXCEPT WERE LINED THROUGH .
`[K . Z/
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`