SciFinder®
`
`Page 1
`
`Session Began October 16, 2019 at 08:37 AM
`
`Task Began October 16, 2019 08:37 AM
`
`Explore references by patent: ( ID 1)
`Patent Number:
`U820180021280
`
`Answer Type:
`Result Count:
`
`References
`1
`
`Detailed display
`From ID:
`
`1
`
`Type:
`
`Levodopa and carbidopa intestinal pharmaceutical gels
`
`Retrieve substance information in 1 reference (ID 2)
`From ID:
`0
`
`Uses
`
`Answer Type:
`Result Count:
`
`Substances
`15
`
`Retrieve reference information in 15 substances (ID 3)
`From ID:
`2
`
`Uses
`
`Answer Type:
`Result Count:
`
`References
`18165
`
`Refine by research topic (ID 4)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`combination of levodopa and carbidopa
`3
`
`References
`1660
`
`Refine by research topic (ID 5)
`
`Research Topic:
`From ID:
`
`Carbopol 971 P
`4
`
`No answers
`
`Refine by research topic (ID 6)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`carboxypolymethylene
`4
`
`References
`7
`
`6
`
`Type:
`
`Modified drug release dosage form
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`6
`
`Subcutaneously infusible levodopa prodrug compositions and methods of
`infusion
`
`6
`
`Muco-adhesive, controlled release formulations of levodopa and/or esters of
`levodopa and uses thereof
`
`6
`
`

`

`Type:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`SciFinder®
`Modified release dosage form
`
`6
`
`Page 2
`
`Subcutaneously infusible levodopa prodrug compositions and methods of
`infusion
`
`6
`
`Type:
`
`Gastroretentive dosage forms for sustained drug delivery
`
`Detailed display
`From ID:
`
`6
`
`Type:
`
`DOPA sustained release formulations for treatments of Parkinson's disease
`
`Refine by research topic (ID 7)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`levodopa and carbidopa combination
`3
`
`References
`951
`
`Refine by research topic (ID 8)
`
`Research Topic:
`From ID:
`
`carbomer
`7
`
`No answers
`
`Refine by research topic (ID 9)
`
`Research Topic:
`From ID:
`
`carbomer homopolymer
`7
`
`No answers
`
`Refine by research topic (ID 10)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`Type:
`
`carboxypolymethylene
`7
`
`References
`2
`
`10
`
`Subcutaneously infusible levodopa prodrug compositions and methods of
`In usion
`
`10
`
`Subcutaneously infusible levodopa prodrug compositions and methods of
`infusion
`
`Task Began October 16, 2019 08:47 AM
`
`Explore substances by ID: 57308—51-7, 500019-90-9 (ID 11)
`
`Answer Type:
`Result Count:
`
`Substances
`1
`
`Retrieve reference information in 1 substance (ID 12)
`From ID:
`11
`
`Uses
`
`Answer Type:
`Result Count:
`
`References
`225
`
`

`

`Refine by research topic (ID 13)
`
`SciFinder®
`
`Page 3
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`carboxypolymethylene
`12
`
`References
`2
`
`13
`
`Rapidly expanding oral composition for gastric retention and controlled release
`of therapeutic agents
`
`13
`
`Type:
`
`Transmucosal film composition and methods of making and using the same
`
`Retrieve reference information in 1 substance (ID 14)
`From ID:
`11
`
`Preparation; Process
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`References
`1
`
`14
`
`Type:
`
`Pharmaceutical composition for biocorrection of the sympathetic-adrenal system
`
`Retrieve reference information in 1 substance (ID 15)
`From ID:
`11
`
`Uses
`
`Answer Type:
`Result Count:
`
`Refine by research topic (ID 16)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`References
`225
`
`acrylic acid polymer
`15
`
`References
`2
`
`16
`
`Rapidly expanding oral composition for gastric retention and controlled release
`of therapeutic agents
`
`16
`
`Type:
`
`Transmucosal film composition and methods of making and using the same
`
`Task Began October 16, 2019 08:59 AM
`
`Explore references by research topic: carboxypolymethylene in pharmaceutical formulation
`
`Research Topic:
`Result Count:
`
`carboxypolymethylene in pharmaceutical formulation
`4
`
`Candidates Selected (ID 17)
`
`268 references were found containing the two concepts "carboxypolymethylene"
`and "pharmaceutical formulation" closely associated with one another.
`
`Automatically removed 11 duplicate MEDLINE answer(s)
`
`2035 references were found where the two concepts "carboxypolymethylene"
`and "pharmaceutical formulation" were present anywhere in the reference.
`
`

`

`Answer Type:
`Result Count:
`
`Refine by research topic (ID 18)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`SciFinder®
`Automatically removed 11 duplicate MEDLINE answer(s)
`References
`
`Page 4
`
`2024
`
`carbomer homopolymer
`17
`
`References
`
`4
`
`18
`
`Formulation optimization of pramipexole dihydrochloride prolong release tablets
`by implementation of design of experiment tool
`
`18
`
`Rheological, mechanical, and bioadhesive behavior of hydrogels to optimize skin
`delivery systems
`
`18
`
`Formulation comprising ingestible particles including polymer, lipid, and
`optionally amino acid, vitamin and/or micronutrient
`
`18
`
`Type:
`
`Formulation comprising particles and a lipase inhibitor
`
`Refine by research topic (ID 19)
`
`Research Topic:
`From ID:
`
`Answer Type:
`Result Count:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`levodopa and carbidopa
`17
`
`References
`
`6
`
`19
`
`Pharmacokinetic evaluation of formulated levodopa methyl ester nasal delivery
`systems
`
`19
`
`Muco-adhesive, controlled release formulations of levodopa and/or esters of
`levodopa and uses thereof
`
`19
`
`Type:
`
`Novel extended release pharmaceutical formulations
`
`Detailed display
`From ID:
`
`Type:
`
`Detailed display
`From ID:
`
`19
`
`Muco-adhesive, controlled release formulations of levodopa and/or esters of
`levodopa and uses thereof
`
`19
`
`Type:
`
`Gastroretentive dosage forms for sustained drug delivery
`
`Detailed display
`From ID:
`
`19
`
`

`

`Type:
`
`Page 5
`SciFinder®
`DOPA sustained release formulations for treatments of Parkinson's disease
`
`Copyrig1t© 2019 American Chemical Society. All Rights Reserved.
`
`Copyrig1t© 1994-2019 Sun Microsystems,|nc. All Rights Reserved. (Java runtime environment)
`
`Copyrigwt © 2019, Yahoo! Inc. All Rights Reserved. (YUI Base, Fonts, Reset CSS)
`
`Copyrig1t© 200-2019, The Dojo Foundation. All Rights Reserved
`
`Copyrigwt © 2019, Exadel, Inc. All Rights Reserved. (JBoss RichFaces)
`
`Copyrig1t© 2002 InfoChem GmbH. All Rights Reserved. (InfoChem's reaction classification program CLASSIFY)
`
`
`
`The following copyright notice applies to Raphael onlszermission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the 'Software'), to
`
`deal in he Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom
`
`the Software is furnished to do so, subject to the following conditionszThe above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.THE
`
`SOFTWARE IS PROVIDED 'AS |S', WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR
`
`A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY,
`
`WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
`
`SOFTWARE.
`
`The following copyright notice applies to Google Closure Templates only:Copyright 2009 Google |nc.Licensed under the Apache License, Version 2.0 (the 'License'); you may not use this file except in
`
`compliance with the License. You may obtain a copy of the License athttp://www.apache.org/licenses/LICENSE-2.0Unless required by applicable law or agreed to in writing, software distributed under
`
`the License is distributed on an 'AS |S' BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions
`
`and limitations underthe License.
`
`Copyright (c) 2010, 2012 Adobe Systems Incorporated, All Rights Reserved, (Source Sans Pro)Licensed under the SIL Open Font License, Version 1.1 (available at: http://scripts.sil.org/OFL)
`
`Copyright 2005-2013 The Dojo Foundation (Dojo Toolkit)Licensed under the Apache License, Version 2.0 (the “License“); you may not use this file except in compliance with the License. You may
`
`obtain a copy of the License at:http://www.apache.org/licenses/LICENSE-2.0Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an “AS IS“
`
`BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.See the License for the specific language governing permissions and limitations under the License.
`
`Copyright (c) 2008 Dmitry Baranovskiy (Raphael)Licensed under the MIT License (available at: http://opensource.org/licenses/MIT)Permission is hereby granted, free of charge, to any person obtaining
`
`a copy of this software and associated documentation files (the “Software“), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish,
`
`distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditionszThe above copyright notice and this
`
`permission notice shall be included in all copies or substantial portions of the Software.THE SOFTWARE IS PROVIDED “AS IS“, WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED,
`
`INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR
`
`COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
`
`CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
`
`CAplus SM: Copyright © 2019 American Chemical Society. All Rights Reserved. (The UK. patent material in this product/service is UK. Crown copyright and is made available with permission.
`
`Copyright © Crown Copyright. The French (FR) patent material in this product/service is made available from Institut National de la Propriete Industrielle (|NPI).)
`
`CAS REGISTRY SM: Copyright © 2019 American Chemical Society. All Rights Reserved. (Some records contain information from GenBank® . See also: Benson D.A., Karsch-Mizarachi |., Lipman
`
`D.J., Ostel J., Rapp B.A., Wheeler D.L. Genbank. Nucl. Acids Res. 28(1):15-18 (2000). Property values tagged with IC are from the ZIC/VINITI data file provided by InfoChem.) CAS Registry is a service
`
`mark of the American Chemical Society. GenBank is a registered trademark of the US. Library of Medicine.
`
`CASREACT ® : Copyright © 2019 American Chemical Society. All Rights Reserved. CASREACT contains reactions from CAS and from: ZIC/VINITI database (1974-1999) provided by InfoChem; INPI
`
`data prior to 1986; Biotransformations database compiled under the direction of Professor Dr. Klaus Kieslich; organic reactions, portions copyright 1996-2006 John Wiley & Sons, Ltd., John Wiley and
`
`Sons, |nc., Organic Reactions |nc., and Organic Syntheses Inc. Reproduced under license. All Rights Reserved.
`
`CHEMCATS ® : Copyright © 2019 American Chemical Society. All Rights Reserved. Chemical supplier information is supplied on an “as is“ basis. Full information regarding substance availability,
`
`price, etc., is provided when you request supplier information.
`
`CHEMLIST ® : Copyright © 2019 American Chemical Society. All Rights Reserved.
`
`

`

`MEDLINE ® : is produced bythe U.S. National Library of Medicine. MEDLINE is a registered trademark of the U.S. National Library of Medicine.
`
`SciFinder®
`
`Page 6
`
`