Receipt: date: 04/20/2017
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`INFORMATION DISCLOSURE —g:§$§m”.am;
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`Attorney DocketNumber
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`Examiner
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`U. S. PATENT DOCUMENTS
`
`US-6221653
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`US-6419883
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`US-6458526
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`US-6587579
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`US-6599693
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`US-6613893
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`US-6773676
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`US-6789965
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`US-6989267
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`US-7125523
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`CAREN; Michael P. etal.
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`BLANCHARD; Alan P.
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`SCHEMBRI; Carol T. et al.
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`BASS; Jay K.
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`BASS; Jay K. et al.
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`BERNDT; Manfred
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`KIM; Namyong et al.
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`SILLMAN; Debra A.
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`MINOR; James M.
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`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
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`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
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`Receipt: date: 04/20/2017
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`Approved for use through 07/31/2016. OMB 0651-0031
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`US-20020095073
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`US-20020160536
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`JACOBS; Alice A. etal.
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`XIAO; Jianming et al.
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`NOVQRADOVSKAYA?
`Natalia et al.
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`BEK; Fritz
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`US-20100004143
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`US-20110230653
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`US-20130045483
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`NOVQRADOVSKAYA?
`Natalia et al.
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`TREUSCH; Sebastian et al.
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`TEMME; Karsten et al.
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`BANYAI; William et al.
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`US-20160264958
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`TORO; Esteban et al.
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`Considered
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`Documents at wwwusgtogov or MPEP 901.04. 3 Enter Office that issued the document, by the two-letter code (WIPO Standard ST.3). For Japanese patent documents, the
`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. 6Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
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`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
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`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
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`

`

`Receipt: date: 04/20/2017
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`Approved for use through 07/31/2016. OMB 0651-0031
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`Complete if Known
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`lnitials*
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`Examiner
`lnitials*
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`US-20160303535
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`US-20160333340
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`US-20160339409
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`US-20160340672
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`BANYAI; William et al.
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`BANYAI; William et al.
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`WU; Cheng-Hsien
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`BANYAI; William et al.
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`BANYAI; William et al.
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`BANYAI; William et al.
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`03-23-2017
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`PECK; Bill James
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`BANYAI; William et al.
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`Pages, Columns, Lines, Where
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`EP-0753057-A1
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`01-15-1997
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`AS [DK]
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`WO-2014035693-A2
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`SCRIPPS
`03-06-2014 RESEARCH INST
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`WO-2015090879-A1
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`06-25-2015
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`[US], et al.
`
`GE HEALTHCARE
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`UK LTD [GB]
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`WO-2016172377-A1
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`TWIST
`10-27-2016 BIOSCIENCE
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`CORP [US]
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`Examiner
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`Date
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`4
`considered. Include copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
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`Documents at wwwusgtogov or MPEP 901.04. 3 Enter Office that issued the document, by the two-letter code (WIPO Standard ST.3). For Japanese patent documents, the
`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. 6Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
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`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
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`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
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`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
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`/KZ/
`
`

`

`Receipt: date: 04/20/2017
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`Approved for use through 07/31/2016. OMB 0651-0031
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`hang, Kaijiang
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`10-05-1995 AS [DK], et al.
`
`
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`Foreign Patent Document
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`FOREIGN PATENT DOCUMENTS
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`WO-2016183100-A1
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`WO-2017053450-A1
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`WO-9526397-A1
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`TWIST
`11-17-2016 BIOSCIENCE
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`CORP [US]
`TWIST
`03-30-2017 BIOSCIENCE
`
`CORP [US]
`
`NOVO NORDISK
`
`Continued on next page
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`Examiner
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`Signature
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`[KAIJIANG ZHANG/
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`Considered
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`09/11/2018
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`Date
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`1
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`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not
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`considered. Include copy of this form with next communication to applicant. Applicant’s unique citation designation number (optional). See Kinds Codes of USPTO Patent
`5
`Documents at wwwusgtogov or MPEP 901.04. 3 Enter Office that issued the document, by the two-letter code (WIPO Standard ST.3). For Japanese patent documents, the
`indication of the year of the reign of the Emperor must precede the serial number of the patent document. Kind of document by the appropriate symbols as indicated on the
`document under WIPO Standard ST.16 if possible. 6Applicant is to place a check mark here if English language Translation is attached. This collection of information is required by
`37 CFR 1.97 and 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the USPTO to process) an application. Confidentiality is
`governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering, preparing, and submitting the completed application
`form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this
`burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
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`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
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`/KZ/
`
`

`

`Receipt: date: 04/20/2017
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`Approved for use through 07/31/2016. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`Substitute for form 1449/PTO
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`Complete if Known
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`—151s7m
`INFORMATION DISCLOSURE —g:§$§m”.am;
`STATEMENT BY APPLICANT —1539
`(Use as many sheets as necessary)
`.
`hang, Kaijiang
`A 4854-701.304
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`|
`
`|
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` N
`
`
`
`Attorney DocketNumber
`
`Examiner
`Initials*
`
`.
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
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`Examiner
`
`,I’KAIJIANG ZHANG/
`
`Date
`
`09/11/2018
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`
`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
`
`/KZ/
`
`

`

`Receipt: date: 04/20/2017
`
`Approved for use through 07/31/2016. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`Substitute for form 1449/PTO
`_
`
`Complete if Known
`
`—151s7m
`INFORMATION DISCLOSURE —g:§$§m”.am;
`STATEMENT BY APPLICANT —1539
`(Use as many sheets as necessary)
`.
`hang, Kaijiang
`A 4854-701.304
`
`|
`
`|
`
`
`
`
`
`Attorney DocketNumber
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
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`Examiner
`
`Date
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`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1-800-786-9199} and select option 2.
`
`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
`
`/KZ/
`
`

`

`Receipt: date: 04/20/2017
`
`Approved for use through 07/31/2016. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`Substitute for form 1449/PTO
`_
`
`Complete if Known
`
`—151s7m
`INFORMATION DISCLOSURE —g:§$§m”.am;
`STATEMENT BY APPLICANT —1539
`(Use as many sheets as necessary)
`.
`hang, Kaijiang
`A 4854-701.304
`
`|
`
`|
`
`Attorney DocketNumber
`
`
`
`
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
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`
`N
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`_I
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`Examiner
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`Date
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`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`
`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
`
`/KZ/
`
`

`

`Receipt: date: 04/20/2017
`
`Approved for use through 07/31/2016. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`SubstItute for form 1449/PTO
`_
`
`Complete if Known
`
`INFORMATION DISCLOSURE
`STATEMENT BY APPLICANT
`(Use as many sheets as necessary)
`
`—151s7m
`
`—:i””thDa‘ed,, Fifi/3m”.
`'
`'a
`
`Art Unit
`
`1639
`
` NON-PATENT LITERATURE DOCUMENTS
`
`
`
`Attorney DocketNumber
`
`hang, Kaiiiang
`I 4854-701.304
`
`Examiner
`Initials*
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`N
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`NEIMAN M.S., On the bases ofthe theory of information retrieval. Radiotekhnika, 1967, N2 5,
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`
`RAFALSKI and MORGANTE, Corn and humans: recombination and linkage disequilibrium in
`two genomes of similar size. Trends in Genetics, 20(2):103-111, 2004.
`
`Examiner
`
`Signature
`
`[KAIJIANG ZI—LANG/
`
`Considered
`
`09/ 11/2018
`
`Date
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`
`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
`
`/KZ/
`
`

`

`Receipt: date: 04/20/2017
`
`Approved for use through 07/31/2016. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`Substitute for form 1449/PTO
`_
`
`Complete if Known
`
`—151s7m
`INFORMATION DISCLOSURE —g:§$§m”.am;
`STATEMENT BY APPLICANT —1539
`(Use as many sheets as necessary)
`.
`hang, Kaijiang
`A 4854-701.304
`
`|
`
`|
`
`Attorney DocketNumber
`
` N
`
`
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`RAJE and MURMA, A Review of electrohydrodynamic-inkjet printing technology.
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`
`International
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`Science, 91 :2106-2117, 2007.
`
`The Hood Laboratory, "Beta Group." Assembly Manual forthe POSaM: The ISB Piezoelelctric
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`pages, May 28, 2004.
`
`The SLIC, Gibson, CPEC and SLiCE assembly methods (and GeneArt Seamless, In-Fusion
`Cloning). 5 pages, available online September 2, 2010.
`
`Examiner
`
`Signature
`
`,I'KAI JIANG ZHANG/
`
`Considered
`
`O 9 l 1 1 1’2 O l 8
`
`Date
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and by the
`USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 2 hours to complete, including gathering,
`preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the amount of time you require to
`complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and Trademark Office, PO. Box 1450, Alexandria, VA
`22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents, P.0. Box 1450, Alexandria, VA 22313-1450.
`If you need assistance in completing the form, call 1-800—PTO-9199 (1 -800-786-91 99} and select option 2.
`
`ALL REFERENCES CONSIDERED EXCEFT WHERE LINED THROUGH.
`
`/KZ/
`
`

`

`Receipt: date: 04/20/2017
`
`Approved for use through 07/31/2016. OMB 0651-0031
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it contains a valid OMB control number.
`
`SubstItute for form 1449/PTO
`_
`
`Complete if Known
`
`—151s7m
`INFORMATION DISCLOSURE —g:§$§m”.am;
`STATEMENT BY APPLICANT —1539
`(Use as many sheets as necessary)
`.
`hang, Kaijiang
`I 4854-701.304
`
`|
`
`|
`
` N
`
`
`
`Attorney DocketNumber
`
`NON-PATENT LITERATURE DOCUMENTS
`
`Examiner
`Initials*
`
`'
`.
`
`Include name ofthe author(in CAPITAL LETTERS),titIe of the article(when appropriate), title of
`the item (book,magazine,journaI,seriaI,symposium,cata|og,etc.),date,page(s),vo|ume-issue
`number(s),publisher, city and/or country where published.
`
`051
`
`US. Patent Application No. 15/245,054 Office Action dated March 21, 2017.
`
`052
`
`US. Patent Application No. 15/245,054 Office Action dated October 19, 2016.
`
`U. S. Patent Application No. 15/377, 547 Office Action dated March 24, 2017.
`
`VAN TASSELL et al. ,SNP discovery and allele frequency estimation by deep sequencing of
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`
`WIJSHOFF, Herman. Structure and fluid-dynamics in Piezo inkjet printheads. Thesis. Venio,
`The Netherlands, published 2008, p. 1-185.
`
`WRIGHT and CHURCH, An open-source oligomicroarray standard for human and mouse.
`Nature Biotechnology, 20:1082-1083, 2002.
`
`XIONG et al., Chemical gene synthesis: Strategies, softwares, error corrections, and
`applications. FEMS Microbiol. Rev., 32:522-540, 2008.
`
`ZHIRNOV et al., Nucleic acid memory. Nature Materials, 15:366, 2016.
`
`Examiner
`Signature
`
`[KAI JIANG ZHANG/
`
`Date
`Considered
`
`C1 ‘3: / 1 1 [2 CI 1 8
`
`*EXAMINER: Initial if reference considered, whether or not citation is in conformance with MPEP 609. Draw line through citation if not in conformance and not considered. Include
`copy of this form with next communication to applicant. 1 Applicant’s unique citation designation number (optional). 2 Applicant is to place a check mark here if English language
`Translation is attached. This collection of information is required by 37 CFR 1.98. The information is required to obtain or retain a benefit by the public which is to file (and

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