Serial Ne. renames
`
`EN THE Cl...AlMS:
`
`Claims ill-~17, 23~27, 295, 34a 3769, ill-43, and 50—57 were previnnsly cancelled. Claim
`
`5 is herein cancelled. Claims l—3, 7-l3, 18, ill, ’22, 283 30, 31, 33, 36, 40, and 49 have been
`
`amended herein“ New claims 58-77 are presented herein. All of the pending claims are
`
`presented below. This listing at claims will replace all prior versions and listings of claims in the
`
`application. Please enter these claims as amended.
`
`Marin " at" the Claims:
`
`
`
`
`1.
`
`(Currently amended) A hispeeific antibody eemprising a first antigen—binding site that
`
`binds delimit} l at“ ErbB-‘Z and a second antigen—binding site that binds,diligent}lint": Ei‘bB—Sg
`
`wherein the antibody eaneedeee its}
`
` \ a liganddndueed reeertter functien ntilirhlid on a
`
`ErbB—Z and ErbBé positive eell.
`
`2.
`
`(Currently amended) The bispeeifie antibody of claim l, wherein the antibody earl
`
`ledaeeiiilnixx ligandsindueed growth ef an lirbB—2 and liith~3 positive cell,
`
`3.
`
`(Currently amended) The bispeciiie antibody of claim 25 wherein the antibody ean
`
`redaee redraw ligandwindnced growth of an ErbB—Q and ErbBuB pesitive eells wherein said the
`
`cell has at least lOOflOO ErbB«2 eelhsnrt‘ace receptors per cell.
`
`4.
`
`
`(Currently amended) The bispecilie antibody of claim it wherein said the eell is an
`
`MCFJ cell, an SKBR—Ft cell, NCl—NS? cell , an 8x903 cell, an Ell—474 cell er a llM’l‘ l eell‘
`
`5.
`
`6.
`
`(Cancelled).
`
`{Previously presented) The hispeeilie antibody of claim l, wherein the second antigen—
`
`binding site interferes with binding of an Eth—3 ligand to ErbBG.
`
`

Accessing this document will incur an additional charge of $.

After purchase, you can access this document again without charge.

Accept $ Charge

This document could not be displayed.

We could not find this document within its docket. Please go back to the docket page and check the link. If that does not work, go back to the docket and refresh it to pull the newest information.

Your account does not support viewing this document.

You need a Paid Account to view this document. Click here to change your account type.

Your account does not support viewing this document.

Set your membership status to view this document.

With a Docket Alarm membership, you'll get a whole lot more, including:

  • Up-to-date information for this case.
  • Email alerts whenever there is an update.
  • Full text search for other cases.
  • Get email alerts whenever a new case matches your search.

Become a Member

One Moment Please

The filing “” is large (MB) and is being downloaded.

Please refresh this page in a few minutes to see if the filing has been downloaded. The filing will also be emailed to you when the download completes.

Your document is on its way!

If you do not receive the document in five minutes, contact support at support@docketalarm.com.

Sealed Document

We are unable to display this document, it may be under a court ordered seal.

If you have proper credentials to access the file, you may proceed directly to the court's system using your government issued username and password.


Access Government Site

We are redirecting you
to a mobile optimized page.

We are unable to display this document.

HTTP Error 500: Internal Server Error

Refresh this Document
Go to the Docket