`Attorney Docket No.: AKBM-14409/US-9/CON
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`REMARKS
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`Claims 1-20 are pending and under examination following entry of the Responseto the
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`Final Office Action filed on April 16, 2015.
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`Applicant respectfully requests that the Examiner additionally consider the disclosure of
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`Tanakaet al., Biosci. Biotech. Biochem. 59(8):1389-93 (1995) which demonstrates that the
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`deleterious PAF-like analogs described in Maranteet al. (1999) 274(10):28395-28404 are readily
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`formed from ether phospholipids found in krill. In fact, as described in the Tanakaabstract:
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`The activity of oxidized krill PC, which was equivalent of 89.8 + 8.8 pmol 16:0
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`PAF/umolofstarting PC, was about five times those of oxidized PCs from salmon roe
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`and sea urchin eggs and about 50 times that of oxidized hen yolk PC.
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`Based on this information, and the knownplatelet aggregation and inflammatory activity of PAF,
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`one of skill in the art would not be motivated to increase the ether phospholipid content of prior
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`art krill oil and would in fact have been motivated to avoid increasing the ether phospholipid
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`content of krill oil. Certainly, one of skill in the art would not have expected that increasing the
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`ether phospholipid contentof krill oil would lead to increased health benefits.
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`CONCLUSION
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`If a telephone interview wouldaid in the prosecution of this application, the Examineris
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`encouragedto call the undersigned collect at (608) 662-1277.
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`Dated:
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`April 23, 2015
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`/J. Mitchell Jones/
`John Mitchell Jones
`Registration No. 44,174
`Casimir Jones, S.C.
`2275 Deming Way,Suite 310
`Middleton, WI, 53562
`(608) 662-1277
`
`
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