INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`APPLICATION
`
`APPLICANT
`
`FAN, Jian-Bing
`
`_
`
`FILING DATE
`
`GROUP
`
`SHEET 1 OF 1
`
`\I
`
`U.S. PATENT DOCUMENTS
`
`EXAMINER‘S CITE
`INITIALS
`
`Publication
`Document Number
`Number-Kind Code2 (if Date MM-DD-
`known)
`YYYY
`4,200,110
`04-29-1980
`
`(/3
`
`“I
`“I
`
`4,349,510
`
`4,499,052
`
`4,499,053
`
`4,563,419
`
`4,582,789
`
`4,682,895
`
`4,687,732
`
`4,672,040
`
`4,751,177
`
`4,683,198
`
`4,683,202
`
`4,707,454
`
`4,785,814
`
`09-14-1982
`
`02-12-198
`
`01-12-198
`
`01-07-198
`
`030101
`
`04-15-1986
`
`07-28-198
`
`08-18-198
`
`06-09-198
`
`\I\I\I
`
`01-14-1988
`
`07-28-1987
`
`07-28-1987
`
`11-17-198
`
`11-22-198
`
`Name of Patentee or Applicant of
`Cited Document
`
`Pages, Columns, Lines,
`Where Relevant Passages or
`Relevant Figures Appear
`
`Peterson, et al.
`Kolehmainen
`
`Fulwyler
`
`Fulwyler
`Ranki, et al.
`Sheldon
`
`Costello
`
`Ward
`
`Josephson
`
`Stabinsky
`Mullins, et al.
`
`Mullins, et al.
`Hendrix
`
`Kane
`
`Walt
`
`L0 “I
`
`Yafuso, et al.
`
`Duck, et al.
`
`Whitehad, et al.
`
`Schneider, et al.
`
`Whiteley, et al.
`
`Gebeyehu, et al.
`
`Landegren, et al.
`Yafuso, et al.
`Macevicz
`
`Duck, et al.
`Soini
`
`Abbott
`
`Betzig, et al.
`Walt
`
`Malek
`
`Cheung
`Walt
`
`11-21-198
`
`11-28-1989
`
`05-01-1990
`
`01-29-1991
`
`03-12-1991
`
`03-26-1991
`
`04-30-1991
`
`07-02-1991
`
`04-14-1992
`
`04-14-1992
`
`05-19-1992
`
`07-14-1992
`
`07-12-1992
`
`09-01-1992
`
`CD\I
`04-18-1989
`
`04-24-198
`
`10-24-198
`
`1.01.0
`11-07-1989
`
`4,822,746
`
`4,824,789
`
`4,876,187
`
`4,879,097
`
`4,882,269
`
`4,883,750
`
`4,921,805
`
`4,988,617
`
`4,999,306
`
`5,002,867
`
`5,011,769
`
`5,028,545
`
`5,104,791
`
`5,105,305
`
`5,114,864
`
`5,130,238
`
`5,132,242
`
`5,143,853
`
`5,143,854
`
`5,144,136
`
`09-01-1992
`
`09-01-1992
`
`Pirrung
`Kubisiak
`
`SDO 172948—10672340229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`APPLICATION
`
`SHEET 2 OF 1
`
`\l
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`5,175,082
`
`12-29-1992
`
`Jeffreys
`
`03030) —--— —
`
`Ammmmm
`
`01-05-1993
`5,175,881
`Sepaniak, et al.
`—--— —
`02-09-1993
`5,185,243
`Ullman, et al.
`—--— —
`03-16-1993
`5,194,300
`Cheung
`—--— —
`04-13-199
`3
`5,202,231
`Drmanac, et al.
`—--— —
`08-03-1993
`5,232,829
`Longiaru, et al.
`—--— —
`09-07-1993
`5,242,794
`Whiteley, et al.
`—--— —
`09-14-199
`5,244,636
`Walt, et al.
`—--— —
`09-14-199
`5,244,813
`Walt, et al.
`—--— —
`10-05-199
`5,250,264
`Walt, et al.
`—--— —
`10-12-199
`Walt
`5,252,494
`—--— —
`10-19-199
`Walt
`5,254,477
`—--— —
`03-29-199
`5,298,741
`Walt, et al.
`—--— —
`04-12-1994
`Cheeseman
`5,302,509
`—--— —
`05-24-1994
`5,314,809
`Erlich, et al.
`—--— —
`06-14-199
`5,320,814
`Walt, et al.
`—--— —
`10-18-199
`Auracher
`5,357,590
`—--— —
`10-18-199
`Auracher
`5,357,590
`—--— —
`02-07-199
`01
`5,387,505
`Wu, et al.
`—--— —
`03-21-199
`5,399,491
`Kacian, et al.
`———--— —
`
`04-04-199
`5,403,71 1
`Walder, et al.
`—--— —
`04-25-199
`5,409,818
`Davey, et al.
`—--— —
`06-27-199
`5,427,930
`Birkenmeyer, et al.
`—--— —
`07-25-199
`5,435,724
`Goodman, et al.
`—--— —
`08-29-1995
`5,445,934
`Fodor, et al.
`—--— —
`08-29-1995
`Rohr
`5,445,970
`—m-— —
`10-03-1995
`Walker
`5,455,166
`—--— —
`12-12-1995
`5,474,895
`Ishii, et al.
`—--— —
`01-02-1996
`Tabuchi
`5,481,629
`—--— —
`02-06-1996
`Chehab
`5,489,507
`—--— —
`02-27-199
`5,494,798
`Gerdt, et al.
`—--— —
`030)
`02-27-199
`5,494,810
`Barany, et al.
`—m-— —
`03-05-1996
`5,496,997
`Pope
`—--— —
`04-02-199
`Cantor
`5,503,980
`—m-— —
`0430-199
`5,512,439
`Homes, et al.
`—m-— —
`0430-199
`5,512,490
`Walt, et al.
`—--— —
`05-14-1996
`5,516,635
`Ekins, et al.
`—--— —
`05-21-1996
`Soini
`5,518,883
`—--— —
`
`##J>
`
`01010101
`
`SDO 172948—10672340229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`SHEET 3 OF 1
`
`\l
`
`APPLICATION
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`Whiteley, et al.
`
`Dahlberg, et al.
`Rava, et al.
`
`Kacian, et al.
`
`Still, et al.
`Kohne
`
`Hubbell, et al.
`
`Charrino, et al.
`
`Singer, et al.
`Honda, et al.
`
`Trulson, et al.
`
`Bhatnagar, et al.
`Newton, et al.
`
`Geysen
`Burczak, et al.
`Brenner
`
`Dahlberg, et al.
`Heller, et al.
`
`05-28-1996
`
`07-30-1996
`
`08-13-199
`
`6
`
`09-10-199
`
`10-15-1996
`
`O 0
`
`10-22-199
`
`1 1 -05-199
`
`30)
`1 1 -26-1996
`
`1 1 -12-199
`
`1 1-19-199
`
`1 1 -26-199
`
`03030)
`
`01-04-1997
`
`01-21-199
`
`\I
`
`01-21-1997
`
`02-1 1 -199
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`\l
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`02-18-199
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`03-25-199
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`05-27-199
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`06-17-199
`Dower, et al.
`——
`07-22-199
`\l
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`
`Walt, et al.
`
`5,521,065
`I—
`5,541 ,31 1
`I—
`5,545,531
`I—
`5,554,516
`I—
`5,565,324
`I—
`5,567,587
`I—
`5,571,639
`I—
`5,573,907
`I—
`5,573,909
`I—
`5,575,849
`I—
`5,578,832
`I—
`5,593,840
`I—
`5,595,890
`I—
`5,595,915
`I—
`5,601,978
`I—
`5,604,097
`I—
`5,614,402
`I—
`5,632,957
`I—
`5,633,972
`I—
`5,639,603
`I—
`5,649,576
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`5,656,241
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`5,660,988
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`5,681,697
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`5,674,698
`I—
`5,679,524
`I—
`5,690,894
`I—
`5,695,940
`I—
`5,705,365
`I—
`5,710,029
`I—
`5,719,028
`I—
`5,733,729
`I—
`5,744,305
`I—
`5,763,175
`I—
`5,770,157
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`SDO 172948—10672340229
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`05-27-199
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`08-12-1997
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`10-28-1997
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`10-21-1997
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`1 1 -25-1997
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`12-09-199
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`01-06-1998
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`01-20-1998
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`02-17-199
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`(I)
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`03-31-1998
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`04-28-1998
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`06-09-199
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`CD
`
`06-23-1998
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`07-14-199
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`oo
`
`07-28-1998
`
`08-1 1 -1998
`
`Seifert, et al.
`
`Duck, et al.
`
`Urdea, et al.
`
`Zarling, et al.
`Nikiforov, et al.
`
`Pinkel, et al.
`
`Drmanac, et al.
`
`Ryder, e tal.
`
`Ryder, et al.
`
`Dahlberg, et al.
`
`Lipshutz, et al.
`Fodor, et al.
`Brenner
`
`Cargill, et al.
`Brenner
`
`Herman, et al.
`
`Backman, et al.
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`SHEET 4 OF 1
`
`\l
`
`APPLICATION
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`_._.
`_.
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`_L
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`5,804,376
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`5,807,522
`
`5,814,524
`
`5,830,655
`
`5,830,711
`
`5,834,758
`
`5,837,196
`
`5,840,256
`
`5,843,669
`
`5,843,767
`
`5,846,710
`
`5,846,717
`
`5,846,719
`
`5,849,544
`
`5,853,989
`
`08-18-1998
`
`08-18-1998
`
`09-01-1998
`
`09-08-199
`
`09-14-199
`
`09-29-199
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`1 1 -O3-199
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`on
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`12-08-1998
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`12-15-199
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`10-1 1 -1994
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`Cantor, et al.
`
`Chee, et al.
`
`Fodor, et al.
`
`Braxton, et al.
`
`Brown, et al.
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`Walt, et al.
`
`Monforte, et al.
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`Barany, et al.
`Trulson, et al.
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`Pinkel, et al.
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`Demers, et al.
`Kaiser
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`Beattie
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`Bajaj
`Brow, et al.
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`Brenner, et al.
`Harris
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`Jeffreys, et al.
`Lizardi
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`Stabile, et al.
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`Chelsky, et al.
`Soloman, et al.
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`Zanzucchi, et al.
`Brenner
`
`Matsue, et al.
`
`Bouma, et al.
`
`Fodor, et al.
`
`Rava, et al.
`
`Zhang, et al.
`Sutton, et al.
`
`Kacian, et al.
`
`Goelet, et al.
`
`Lough, et al.
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`Wang, et al.
`
`Wong
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`Zhiang, et al.
`Nikiforov, et al.
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`03-30-199
`
`03-30-199
`
`03-30-199
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`07-13-199
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`08-24-1999
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`10-26-1999
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`12-29-199
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`12-29-1998
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`02-16-1999
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`05-04-1999
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`5,854,033
`
`5,854,684
`
`5,856,083
`
`5,858,732
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`5,863,708
`
`5,863,722
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`5,866,321
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`5,869,252
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`5,871,928
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`5,874,219
`
`5,876,924
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`5,888,819
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`5,900,481
`
`5,922,617
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`5,935,793
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`
`—————————————————— ——————————————————
`
`SDO 172948—1.067234.0229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`SHEET 5 OF 1
`
`\l
`
`APPLICATION
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`5,976,797
`
`5,981,180
`
`5,994,066
`
`5,998,175
`
`6,001,564
`
`6,013,440
`
`6,013,456
`
`6,017,738
`
`6,023,540
`
`6,025,601
`
`6,027,840
`
`6,027,889
`
`6,037,186
`
`6,040,138
`
`6,045,996
`
`6,051,380
`
`6,054,564
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`1 1 -02-1999
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`03-21-2000
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`Mitsuhashi
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`Chandler, et al.
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`Bergeron, et al.
`Akhavan-Tafti
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`Bergeron, et al.
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`Lipshutz, et al.
`Akhavan-Tafti
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`Morris, et al.
`
`Walt, et al.
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`Trulson, et al.
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`Bratnayar, et al.
`Lubin, et al.
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`Lockhart, et al.
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`Weisburg, et al.
`Fodor, et al.
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`Balaban, eet al.
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`Balaban, et al.
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`08-01-200
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`04-03-2001
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`04-10-2001
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`04-24-2001
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`6,060,245
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`6,066,454
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`6,071,748
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`6,074,614
`
`6,083,753
`
`6,083,763
`
`6,090,558
`
`6,096,496
`
`6,110,678
`
`6,124,102
`
`6,143,495
`
`6,172,218
`
`6,183,960
`
`6,185,561
`
`6,188,783
`
`6,197,506
`
`6,200,737
`
`6,200,756
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`—————————————————— ——————————————————
`
`SDO 172948—10672340229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`SHEET 6 OF 1
`
`\l
`
`APPLICATION
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`6,225,064
`
`6,225,625
`
`6,229,91 1
`
`6,248,539
`
`6,251,594
`
`6,251,639
`
`6,255,625
`
`6,261,776
`
`6,265,171
`
`6,266,459
`
`6,268,148
`
`6,274,323
`
`6,280,935
`
`6,280,949
`
`6,284,465
`
`6,291,166
`
`6,291,183
`
`6,300,071
`
`6,306,643
`
`05-01-2001
`
`05-01-2001
`
`05-08-2001
`
`06-19-2001
`
`06-26-2001
`
`06-26-2001
`
`05-01-2001
`
`07-17-2001
`
`07-24-2001
`
`07-24-2001
`
`07-31-2001
`
`08-14-2001
`
`08-28-2001
`
`08-28-2001
`
`09-04-2001
`
`09-18-2001
`
`09-18-2001
`
`10-19-2001
`
`10-23-2001
`
`Uematsu, et al.
`
`Pirrung, et al.
`Balaban,et al.
`
`Ghadiri, et al.
`
`Gonzalgo, et al.
`Kurn
`
`Pirrung, et al.
`
`Pirrung, et al.
`Herman, et al.
`
`Walt, et al.
`
`Barany, et al.
`Bruchez, et al.
`Macevicz
`
`Lizardi
`
`Wolber
`
`Gerdes, et al.
`
`Pirrung, et al.
`
`LOCI)0&0
`22
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`10-23-2001
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`10-30-2001
`
`1 1 -13-2001
`
`12-04-2001
`
`12-1 1 -2001
`
`12-18-2001
`
`01-01-2002
`
`01-29-2002
`
`02-12-2002
`
`03-12-2002
`
`03-12-2002
`
`04-16-2002
`
`06-04-200
`
`06-1 1 -200
`
`07-09-200
`
`mm
`l\)
`
`08-06-2002
`
`03-18-200
`
`08-27-2002
`
`09-17-2002
`
`Vuylsteke, et al.
`Gentalen, et al.
`Balaban
`
`Fodor, et al.
`
`Lizardi, et al.
`
`Walt, et al.
`Lizardi
`
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`
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`
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`
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`
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`
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`
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`
`Pirrung, et al.
`Chee, et al.
`
`Barany, et al.
`
`Lipshutz, et al.
`Fodor, et al.
`
`—————————————————— ——————————————————
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`m o \l
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`
`6,335,165
`
`6,342,389
`
`6,346,413
`
`6,355,431
`
`6,355,432
`
`6,372,813
`
`6,399,365
`
`6,403,320
`
`6,416,952
`
`6,429,027
`
`6,534,293
`
`mmmmPS”
`
`6,440,667
`
`6,451,536
`
`SDO 172948—10672340229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`APPLICATION
`
`SHEET 7 OF 1
`
`\l
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`commmm
`
`04-08-2003
`6,544,732
`-——
`12-10-2002
`6,491,871
`-——
`04-08-2003
`6,544,739
`-——
`06-10-2003
`6,576,424
`-——
`08-12-200
`6,604,902
`-——
`08-12-200
`6,605,432
`-——
`08-26-2003
`6,610,482
`-——
`09-09-200
`6,618,679
`-——
`09-30-200
`6,627,402
`-——
`1 1 -1 1 -200
`6,646,243
`-——
`1 1 -02-200
`4:
`6,812,005
`-——
`02-22-2005
`6,858,394
`-——
`09-13-2005
`6,942,968
`-——
`12-22-2000
`7,033,754
`-——
`06-13-2006
`7,060,431
`-——
`10-03-2006
`7,1 15,884
`-——
`10-1 1 -2001
`2001/0029049
`-——
`10-17-2002
`2002/0150921
`-——
`1 1 -14-2002
`2002/0168645
`-——
`1 1 -28-2002
`2002/0177141
`-——
`06-12-2007
`2004/0101835
`-——
`01-17-200
`2002/0006617
`-——
`04-04-200
`2002/0039728
`-——
`05-02-2002
`2002/0051971
`-——
`05-30-200
`2002/0065779
`-——
`09-05-200
`2002/0122612
`-——
`09-19-200
`l\)
`2002/0132241
`-——
`09-26-2002
`2002/0137056
`-——
`09-26-2002
`2002/0137086
`-——
`02-06-200
`m
`2003/0027126
`-——
`02-20-2003
`2003/0036064
`-——
`05-01-2003
`2003/0082600
`-——
`06-12-2003
`2003/0108900
`-——
`07-26-2003
`2003/0119025
`-——
`07-10-2003
`2003/0129620
`-——
`08-28-2003
`2003/0162194
`-——
`09-1 1 -200
`2003/0170684
`-——
`1 1 -13-2003
`2003/0211489
`C (I)
`-——
`
`mmmmmmmmmmmmmmmmP90369990.“
`
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`
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`
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`mm0101N97.
`mmmmmm4.090.
`
`m 0)I“.
`
`DO 172948—10672340229
`
`m S
`
`Chee, et al.
`
`Fodor, et al.
`
`Fodor, et al.
`
`Fodor, et al.
`
`Norris, et al.
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`
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`
`Chee, et al.
`Wait
`
`Wait, et al.
`
`Barany, et al.
`
`Taylor
`Chee, et al.
`
`Willis, et al.
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`Fan, et al.
`Kain
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`Oliphant
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`Olek, et al.
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`Fan
`
`Shen
`
`mmmm
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`APPLICATION
`
`SHEET 8 OF 1
`
`\l
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`Olek, et al.
`
`Jones, et al.
`
`Wigler, et al.
`Fan, et al.
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`Olek, et al.
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`07-15-200
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`4:
`
`07-15-200
`
`4s
`
`11-25-2004
`
`12-09-2004
`
`12-23-200
`
`12-30-200
`
`03-10-2005
`
`0)Ah
`
`12-07-200
`
`12-07-200
`
`cncn
`05-07-1996
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`11-10-1998
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`01-09-2000
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`Stuelpnagel, et al.
`06-28-2000
`FOREIGN PATENT DOCUMENTS
`
`2004/0072197
`
`2004/0137473
`
`2004/0137498
`
`2004/0234960
`
`2004/0248090
`
`2004/0259100
`
`2004/0265814
`
`2005/0053937
`
`2006/0275782
`
`2006/0275782
`
`H I1 531
`
`09/189543
`
`09/500555
`
`09/606369
`
`CCCCCCCCCCCCCCC
`
`(DC/JCDCDCDCDCDCDCDCDCDCDCDCD
`
`C!)
`
`2006/0008824
`
`01-12-200
`
`_
`
`(PTO 1449)
`
`US
`
`2004/0023230
`
`————————
`
`mmmmPS”
`I\) O7.01
`
`I\) O O
`m 0).\‘.
`
`mMN\IamI"$090
`
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`—-
`
`I\) \I(D
`m \lP.
`
`mm\l\l07.01
`l.\‘.
`m \, 9°
`
`i\
`
`———————
`
`EXAMINER'S
`INITIALS
`
` Z
`
`Foreign Patent
`Document
`Country Codes _
`Number 4 —Kind
`Code5 (if known)
`EP0139489
`
`EP0238332
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`EP0269764
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`EP0336731
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`EP0478319
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`EP0614987
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`EP0723146
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`EP0799897
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`EP1121465
`
`Publication
`Date
`MM-DD-
`YYYY
`
`Name of Patentee or
`Applicant of Cited
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`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`SHEET 9 OF 1
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`\l
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`APPLICATION
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`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
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`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`SHEET & OF I_7
`
`APPLICATION
`
`_
`
`(PTO 1449)
`
`APPLICANT
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`FAN, Jian-Bing
`
`FILING DATE
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`July 21, 2009
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`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET No.
`067234-0229
`
`SERIAL No.
`12/507,022
`
`APPLICATION
`
`SHEET A OF I_7
`
`_
`
`(PTO 1449)
`
`65.
`i
`366.
`
`W0 02/083705
`
`WO 02/086163
`
`04-15-2002
`
`10-31-2002
`
`367.
`
`368.
`
`WO 02/18649
`
`08-24-2002
`
`WO 02/34942
`
`10-23-2001
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`John Hopkins
`Karolinska Innovations
`w
`
`Lovelace Resp.
`Research Institute
`
`Cancer Research
`Ventures LTD
`
`WO 02/57491
`
`WO 02/61143
`
`WO 03/048732
`
`WO 04/051224
`
`WO 05/068656
`
`07-25-2002
`
`Willis
`
`08-08-2002
`
`06-12-2003
`
`06-17-2004
`
`07-28-2005
`
`Brown, et al.
`_|_|
`
`an, et al.
`
`llumina, lnc.
`olexa Limited
`(I)
`
`369.
`
`370.
`
`-----
`
`371.
`
`372.
`
`373.
`
`(D (I)P“)
`
`EXAMINER'S
`INITIALS
`
`OTHER ART (Including Author, Title, Date, Pertinent Pages, Etc.)
`
`Include name of the author (in CAPITAL LETTERS), title of the article (when appropriate), title of
`the item (book, magazine, journal, serial, symposium, catalog, etc.), date, page(s), volume-issue
`number(s), publisher, city and/or country where published.
`
`Abel, et al., “Fiber-Optic Evanescnet Wave Biosensor for the Detection of Oligonucleotides, “ Anal
`Chem 68:2905-2912 (1996).
`
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`(1993).
`
`Akama, et al., “Restriction landmark genomic scanning (RLGS-M) based genome-wide scanning
`of mouse liver tumors for alterations in DNA methylatin status,” Cancer Res 57 (15):3294-3299
`
`-
`
`Anonymous, "Fluorescent Microspheres, Tech Note 19, Bangs Laboratories (1997).
`
`Anonymous, “Microsphere Detection Guide", Bangs Laboratories 1-8 (1998).
`Bangs, L. B., "Immunological Applications of Microspheres," The Latex Course, Bangs
`Laboratories Inc. Carmel
`IN 1-29 2006 .
`
`00 \I \I
`
`(A) \I CD
`
`.
`379.
`
`380.
`
`381.
`
`00 (I)I\)
`
`Banér, et al., “More keys to padlock probes: mechanisms for high-throughput nucleic acid
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`Proc of the Ntl Academ of Sciences 88:189-193 1991 .
`
`Barnard,
`
`"A Fibre-Optic Chemical Sensor with Discrete Sensing Sites," Nature 353:338-340
`
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`16(4):168-174 (2000).
`
`384.
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`BioTechnigues 17(5):896-901 (1994).
`
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`386.
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`Placenta,” J Clin Endocrinol Metab 83(8): 2878-2885 (1998).
`
`—- Broude, et al., "Enhanced DNA sequencing by hybridization," PNAS 91 :3072-3076 (1994). -
`
`SDO 172948—10672340229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`SHEET g OF I_7
`
`APPLICATION
`
`_
`
`(PTO 1449)
`
`APPLICANT
`
`FAN, Jian-Bing
`
`FILING DATE
`
`July 21, 2009
`
`GROUP
`
`1634
`
`Chen, "A Microsphere-Based Assay for Multiplexed Single Nucleotide Polymorphism Analysis
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`
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`
`
`
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`
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`
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`
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`
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`
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`Tag Arrays,” Genome Res 10(6):853-860 (2000).
`
`Feil, et al., “Methylation analysis on individual chromosomes: improved protocol for bisuphphite
`genomic sequencing,” Nuc Acids Res 22(4):695-296 (1994).
`
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`counterparts,” Nature 301 :89-92 (1983).
`
`Ferguson, et al., "A Fiber-Optic DNA Biosensor Microarray for the Analysis of Gene Expression,"
`Nature Biotechnol. 14:1681-1684 (1996).
`
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`(1991).
`
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`
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`
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`
`406.
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`
`409.
`
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`
`SDO 172948—1.067234.0229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`SHEET g OF I_7
`
`APPLICATION
`
`APPLICANT
`
`FAN, Jian-Bing
`
`
`
`_
`
`FILING DATE
`
`GROUP
`
`Golub, et al., “Molecular classification of cancer: class discovery and class prediction by gene
`expression monitoring,” Science 286:531-537 (1999).
`
`Gonzalgo, et al., “Identification and characterization of differentially methylated regions of
`genomic DNA by methylation-sensitive arbitrarily primed PCR,” Cancer Res 57(4):594-599
`(1997).
`
`Gonzalgo, et al., “Quantitative methylation analysis using methylation sensitive single nucleotide
`primer extension (Ms-SNuPE),” Methods 27:128—133 (2002).
`
`Gonzalgo, et al., “Rapid quantitation of methylation differences at specific sites using methylation-
`sensitive single nucleotide primer extension (Ms-SNuPE),” Nuc Acids Res 25(12):2529-2531
`(1997).
`
`Goto, “Regulation of X-chromosome inactivation in development in mice and humans,” Microbiol
`Mol Biol 62:362-378 (1998).
`
`Hammons, et al., “Specific site methylation in the 5’-flanking region of CYP1AS:interindividual
`differences in human livers,” Life Sci 69:839-945 (2001).
`
`Hanada, et al., “bcl-s-gene hypomethylation and high-level expression in B-cell chronic
`lymphocytic leukemia,” Blood 82(6):1820-1828 (1993).
`
`Hatch, et al., "Rolling circle amplification of DNA immobilized on solid surfaces and its application
`to multiplex mutation detection," Genetic Anal Biomolecular Eng 15:35-40 (1999).
`
`Hayashizaki, et al., “Restriction landmark genomic scanning method and its various applications,”
`Electrophoresis 14:251-258 (1993).
`
`Healey, et al., "Development of a Penicillin Biosensor Using a Single Optical Imaging Fiber,"
`SPIE Proc 2388:568—573 (1995).
`
`Healey, et al., "Improved Fiber-Optic Chemical Sensor for Penicillin," Anal Chemistry,
`67(24):4471-4476 (1995).
`
`Healey, et al., "Fiber Optic DNA Sensory Array Capable of Detecting Point Mutations," Anal
`Biochemistry 251(2.): 270-279(.1997)
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`antibodies and polymerase chain reaction ” Nucleic Acids Res 23(3). 522-529 (1995).
`
`Herman, et al., “Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant
`DNA methylation in all common human cancers,” Cancer Res 55:4525-4530 (1995).
`
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`islands,” PNAS 93:9821-9826 (1996).
`
`Hermanson, et al., “Bioconjugate Techniques,” Academic Press, San Diego, CA, 1996 pp. 640-
`
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`Genotyping,” PNAS, 97(22):12164-12169 (2000).
`
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`Monitoring,” J of Lightwave Tech LT-5(7):1027-1033 (1987).
`
`SDO 172948—1.067234.0229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`SHEET i OF I_7
`
`APPLICATION
`
`APPLICANT
`
`FAN, Jian-Bing
`
`_
`
`FILING DATE
`
`GROUP
`
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`
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`
`SDO 172948—1.067234.0229
`
`

`

`INFORMATION DISCLOSURE
`CITATION IN AN
`
`ATTY. DOCKET NO.
`067234-0229
`
`SERIAL NO.
`12/507,022
`
`SHEET 1_5 OF I_7
`
`APPLICATION
`
`APPLICANT
`
`FAN, Jian-Bing
`
`_
`
`FILING DATE
`
`GROUP
`
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