L1
`L2
`L3
`
`L4
`L5
`
`L6
`
`STRUCTURE UPLOADED
`50 S L1 SSS SAM
`6864 S L1 SSS FULL
`
`FILE
`
`'CAPLUS' ENTERED AT 15:44:40 ON 22 NOV 2010
`3386 S L3
`1 S US 20070259875/PN
`E TASTE RECEPTORS + OLD,NEW/IT
`SET EXPAND CONTINUOUS
`
`E TASTE RECEPTORS+OLD,NEW/IT
`1 S
`L4 AND (TASTE/IT OR TASTE RECEPTORS/IT OR
`
`TASTEBUD?/IT)
`L7
`L8
`?SOUR? 0
`L9
`L10
`L11
`CATION? RECEP
`L12
`?BITTER?
`L13
`L14
`L15
`CATION? RECEP
`L16
`L17
`
`0 S
`3 S
`
`2 S
`0 S
`0 S
`
`4 S
`
`2 S
`1 S
`1 S
`
`0 S
`50 S
`
`TRIPHOSPHAT?) OR
`L18
`38 S
`L19
`50 S
`
`L6 NOT L5
`
`L4
`
`(L)
`
`(?TASTE? OR ?TRPM? OR ?PAPILLA? OR ?SWEET? OR
`
`L8 NOT L5
`
`L9 AND (PY<:2006 OR PRY<:2006 OR AY<:2006)
`L4
`(L)
`(?TRPM? OR (TRANSIENT RECEPTOR POTENTIAL
`
`L4 AND (?TASTE? OR ?TRPM? OR ?PAPILLA? OR ?SWEET? OR
`
`L12 AND (PY<:2006 OR PRY<:2006 OR AY<:2006)
`L13 NOT L5
`
`L4 AND (?TRPM? OR (TRANSIENT RECEPTOR POTENTIAL
`
`L15 NOT L5
`
`L4 AND (PHOSPHOLIPASE? OR ?PLC? OR (INOSITOL
`
`L17 AND (PY<=2006 OR PRY<=2006 OR AY<=2006)
`L4 AND (PHOSPHOLIPASE? OR ?PLC? OR (INOSITOL
`
`TRIPHOSPHAT?) OR
`L20
`1 S
`L4 AND (PHOSPHOLIPASE? OR (INOSITOL TRIPHOSPHAT?))
`L21
`1 S
`L20 NOT L5
`E
`ATWAL KARNAIL?/AU
`SET EXPAND CONTINUOUS
`E25—26
`94 S
`ATWAL ANITA?/AU
`BRYANT ROBERT?/AU
`BRYANT ROB?/AU
`E62,65-72
`E62,E65-72
`LEE SEUNGHUN?/AU
`E73-74
`
`L22
`
`L23
`L24
`
`L25
`
`E E E
`
`0 S
`265 S
`E
`32 S
`E
`2 S
`E
`27 S
`413 S
`1 S
`0 S
`13 S
`
`L26
`
`L27
`L28
`L29
`L30
`L31
`?BITTER
`L32
`L33
`
`PALMER ROY?/AU
`E85—86
`CERNE ROK?/AU
`E97-98
`L22 OR L24 OR L25 OR L26 OR L27
`L4 AND L28
`L29 NOT
`L5
`L28 AND
`
`(?TASTE? OR ?TRPM? OR ?PAPILLA? OR ?SWEET? OR
`
`7 S
`L31 AND
`6 S L32 NOT
`
`(PY<:2006 OR PRY<:2006 OR AY<:2006)
`L5
`
`
`
`L1
`
`L1
`
`STRUCTURE UP
`
`LOADED
`
`STRUCTURE UPLOADED
`
`=> d ll
`L1 HAS NO ANSWERS
`STR
`Ll
`
`tam
`
`L2
`L3
`
`L4
`
`L4
`
`AB
`
`50 S L1 SSS SAM
`6864 S L1 SSS FULL
`
`FILE 'CAPLUS' ENTERED A
`
`T 17:05:32 ON 22 NOV 2010
`
`1 S L3 AND (?TRPA? OR ?TRP?)
`
`ANSWER 1 OF 1
`
`CAPLUS
`
`COPYRIGHT 2010 ACS on STN
`
`The present invention is directed to compns. containing and
`
`methods of using a triaryl substituted imidazole derivs. as
`
`
`inhibitors of certain taste perceptions and functions.
`The
`invention is also directed to compns. comprising a triaryl
`substituted imidazole derivative as a pharmaceutical, veterinary,
`
`food, cosmetic, or dental hygienic composition Thus, a >90%
`
`
`
`inhibition 0: TRPM5 current was found when TRPM5 transfected cells
`
`were pretreated with 10 mM of 2—(4—nitrophenyl)—4,5—diphenyl-1H-
`imidazole.
`ACCESSION NUMBER:
`DOCUMENT NUMBER:
`TITLE:
`
`CAPLUS Full—text
`
`200
`7:1278466
`147:508528
`Tri
`tas
`
`aryl substituted imidazole derivatives and
`
`te—inhibiting uses thereo:
`al, Karnail 8.; Bryant, Robert W.; Lee,
`
`INVENTOR(S):
`Seunghun
`
`PATENT ASSIGNEE(S):
`SOURCE:
`
`DOCUMENT TYPE:
`
`Atw
`
`Pau 1; Palmer, Roy Kyle; Cerne, Rok
`Redpoint Bio Corporation, USA
`PCT Int. Appl.,
`63 pp.
`CODEN: PIXXD2
`Patent
`
`LANGUAGE:
`FAMILY ACC. NUM. COUNT:
`PATENT INFORMATION:
`
`English
`l
`
`
`
`PATENT NO.
`
`KIND
`
`DATE
`
`APPLICATION NO.
`
`NO 2007127479
`20070430
`NO 2007127479
`
`A2
`
`A3
`
`20071108
`
`NO 2007—US10495
`
`20080103
`
`N:
`
`AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BN, BY,
`
`BZ, CA,
`
`EI, GB,
`
`KG, KM,
`
`ME, MG,
`
`PL, PT,
`
`TN, TR,
`
`HU,
`
`IE,
`
`TR, BF,
`
`TG, BN,
`
`AM, AZ,
`
`CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES,
`
`GD, GE, GH, GM, GT, HN, HR, HU,
`
`ID,
`
`IL,
`
`IN,
`
`IS, JP, KE,
`
`KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD,
`
`MK, MN, MN, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH,
`
`RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM,
`
`TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZN
`RN: AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, EI, ER, GB, GR,
`
`IS,
`
`IT, LT, LU, Lv, MC, MT, NL, PL, PT, RO, SE, SI, SK,
`
`BJ, CF, CG, CI, CM, GA, GN, GQ, GN, ML, MR, NE, SN, TD,
`
`GH, GM, KE, LS, MN, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZN,
`
`BY, KG, KZ, MD, RU, TJ, TM, AP, EA, EP, OA
`US 20070259875
`A1
`20071108
`US 2007—797082
`20070430
`EP 2015638
`20070430
`
`A2
`
`20090121
`
`EP 2007—776533
`
`R:
`
`AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, EI, FR, GB, GR,
`
`IS,
`
`IT, LI, LT, LU, Lv, MC, MT, NL, PL, PT, RO, SE, SI,
`
`HU,
`
`IE,
`
`SK, TR,
`
`AL, BA, HR, MK, RS
`PRIORITY APPLN.
`INEO.:
`20060428
`
`US 2006—796235P
`
`NO 2007—US10495
`
`P
`
`N
`
`20070430
`ASSIGNMENT HISTORY FOR US PATENT AVAILABLE IN LSUS DISPLAY FORMAT
`
`L1
`L2
`L3
`L4
`
`L4
`
`STRUCTURE UPLOADED
`0 S Ll SSS SAM
`0 S Ll SSS FULL
`STRUCTURE UPLOADED
`
`STRUCTURE UPLOADED
`
`2) d 14
`L4 HAS NO ANSWERS
`L4
`STR
`
`
`
`l \
`
`G1
`
`G1 OH,C02H, COOH, C (O) CHS,NH2
`
`16 S L4 SSS
`367 S L4 SSS
`
`SAM
`FULL
`
`FILE
`
`'CAPLUS' ENTERED AT 13:48:31 ON 16 DEC 2010
`286 S L6
`
`26 S L6/THU
`21 S L8 AND
`
`(PY<=2006 OR AY<=2006 OR PRY<=2006)
`
`ANSWER 2 OF 21
`
`CAPLUS
`
`COPYRIGHT 2010 ACS on STN
`
`L5
`L6
`
`L7
`
`L8
`L9
`
`L9
`AB
`
`The
`
`The present invention is directed to compns.
`containing and
`as
`
`methods 0: using a triaryl substituted imidazole derivs.
`
`
`functions.
`inhibitors 0: certain taste perceptions and
`invention is also directed to compns.
`comprising a triaryl
`substituted imidazole derivative as a pharmaceutical,
`veterinary,
`
`food,
`cosmetic,
`Thus, a >90%
`or dental hygienic composition
`
`
`inhibition 0: TRPM5 current was
`found when TRPM5 transfected cells
`
`were pretreated with 10 mM 0:
`imidazole.
`ACCESSION NUMBER:
`DOCUMENT NUMBER:
`TITLE:
`
`2—(4—nitrophenyl)—4,5—diphenyl-1H-
`
`2007:1278466
`147:508528
`
`CAPLUS Full-text
`
`Triaryl substituted imidazole derivatives and
`taste—inhibiting uses thereof
`Atwal, Karnail S.; Bryant, Robert W.; Lee,
`
`INVENTOR(S):
`Seunghun
`
`PATENT ASSIGNEE(S):
`SOURCE:
`
`DOCUMENT TYPE:
`LANGUAGE:
`FAMILY ACC. NUM. COUNT:
`PATENT INFORMATION:
`
`Paul; Palmer, Roy Kyle; Cerne, Rok
`Redpoint Bio Corporation, USA
`PCT Int. Appl.,
`63 pp.
`CODEN: PIXXDZ
`Patent
`
`English
`1
`
`PATENT NO.
`
`KIND
`
`DATE
`
`APPLICATION NO.
`
`DATE
`
`WO 2007127479
`20070430 <——
`
`A2
`
`20071108
`
`WO 2007—US10495
`
`
