`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENTOF COMMERCE
`United Slates Patent and Trademark Office
`Address:
`€COOMMISSIOONICR OR PATINTS.
`Pad tox | 4505
`Alexandria, Virgina 22414-1450
`ww Mpa oy
`
` APPLICATIORN NOL
`
`15/966. 508
`
`ISST1S IRATE
`
`11/24/7020
`
`PATENT NO.
`
`10842813
`
`ATTORSISY DOCKIGT Nod
`
`CONPIRMATION SOL
`
`(755.101 CON BP
`
`2585
`
`54434
`
`TAO
`
`Pi/200
`
`BOOTH UDALL FULLER, PLC
`1255 W. Rio Salado Pkwy.
`Suite 215
`‘Toinpe, AZ 85281
`
`ISSUE NOTIFICATION
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`Determination of Patent Term Adjustment under 35 U.S.C. 154 (b)
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`The Patent Term Adjustmentis 157 day(s}. Any patent to issue from the above-identified application will include
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`If a Continued Prosecution Application (CPA) wasfiled in the above-identified application, the filing date that
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`Applicant will be able to obtain more detailed information by accessing the Patent Application Information
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`Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the Office
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`APPLICANT{s) (Please sce PAIR WEBsite http://pair.uspto.gov for additional applicants):
`
`Jon Lundberg, Dyursholm, SWEDEN;
`Heartheet Ltd., Ashbocking, UNTTHED KINGDOM
`Hddie Weitzhere, Stockholm, SWEDEN;
`
`The United States represents the largest, most dynamic marketplace in the world and is an innaralleled lacation
`for business Investment, innovation, and commercialization of ne
`resources and advantages for those who invest and manufacture
`works to encourage and facilitate business investment. To learn n
`the world to develop technology, manufacture products, and grow
`
`Human Power of N Compan
`pany
`EX1070
`Page | of 562
`
`TRIOA (Rev. 10/09)
`
`Human Power of N Company
`EX1070
`Page 1 of 562
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`

`

`
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENTOF COMMERCE
`United Slates Patent and Trademark Office
`Address:
`€COOMMISSIOONICR OR PATINTS.
`PAX [ox | 4505
`Alexandria, Virgina 22413-1450
`ww Maplo ytoy
`
` APPLICATIONS NOL
`
`ATTORSISY DOCKIFT NO
`
`CONPIRMATION SOL
`
`(755.101 CON BP
`
`2585
`
`15/966. 508
`
`ISSU1 RATE
`
`11/24/7020
`
`PATENT NO.
`
`10842813
`
`54434
`
`Tao
`
`PLOH/2000
`
`BOOTH UDALL FULLER, PLC
`1255 W. Rio Salado Pkwy.
`Suite 215
`‘Toimpe, AZ 85281
`
`ISSUE NOTIFICATION
`
`The projected patent numberand issue date are specified above.
`
`Determination of Patent Term Adjustment under 35 U.S.C. 154 (b)
`(applicationfiled on or after May 29, 2000)
`
`The Patent Term Adjustmentis 157 day(s}. Any patent to issue from the above-identified application will include
`an indication of the adjustment on the front page.
`
`If a Continued Prosecution Application (CPA) wasfiled in the above-identified application, the filing date that
`determines Patent Term Adjustmentis the filing date of the most recent CPA.
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`Applicant will be able to obtain more detailed information by accessing the Patent Application Information
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`Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the Office
`of Patent Legal Administration at (571)-272-7702. Questions relating to issue and publication fee payments
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`(571}-272-4200.
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`APPLICANT{s) (Please sce PAIR WEBsite http://pair.uspto.gev for additional applicants):
`
`Jon Lundberg, Dyursholm, SWEDEN;
`Heartheet Ltd., Ashbocking, UNTTHED KINGDOM
`Hddie Weitzhere, Stockholm, SWEDEN;
`
`The United States represents the largest, most dynamic marketplace in the world and is an unparalleled location
`for business investment, innovation, and commercialization of new technologies. The USA offers tremendous
`resources and advantages for those who invest and manufacture goods here. Through SelectUSA, ournation
`works to encourage and facilitate business investment. To learn more about why the USAis the best country in
`the world to develop technology, manufacture products, and grow your business, visit SelectUSA.gov,
`TRIOS (Rev. 10/09)
`
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`(_hange{s) applied
`to document,
`ANBILY
`
`P005/004884
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`P006/11601
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`P004/056376
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`VO08661
`
`P007014334
`
`
`Examiner Name
`
`Attorney Docket Number
`
`| 1255.101 CON BP
`
`Pe
`Pe
`
`Po
`be
`
`01/2005
`
`HE GOVERNMENT OF
`HE UNITED STATES
`OF AMERICA
`
`
`
`2008-10-18
`
`ITROMED, INC.
`
`page 2, line 22-page 7,
`line 10; claim 1;
`example 1
`
`
`
`
`
`2004-07-08
`
`2008-12-31
`
`Spannagel
`
`2007-02-01
`
`atreon Inc, Corresp wi
`P4908980
`
`poe
` S EDERGVISTefal.,DirectDemonstrationofNOFormationInViveFromOrganicNitritesandNitrates,and
`
`If you wish to add additional Foreign Patent Decumentcitation information please click the Add button
`NON-PATENTLITERATURE DOCUMENTS
`
`[Remove]
`
`OKCE, L-Arginine and Hypertension, J. Nutr. 134: 28075-28118, 2004.
`
`PARENTetal,Nitroglycerinreducesmyocardialoxygenconsumptionduringexercisedespifevasculartolerance,Am
`
`Physiol Heart Circ Physiol 290: H1226-H1234, 2005.
`
`||
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`3
`
`orrelation to Effects of Blood Pressure and to In Vilro Effects, Biochemical Pharmacology, Vol. 47, No. 6, pp.
`047-1053,1994.
`
`EFS Web 2.1.18
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`. .,.|Inclide name of the author {in CAPITAL LETTERS},title of the article (when appropriate), title of the item
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`:
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`(book, magazine, journal, serial, sympesium, catalog, etc), date, pages(s}, volume-issue number(s},
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`No
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`15/966 ,508 - GAU: 1621
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`INFORMATION DISCLOSURE First Named Inventor|Jon Lundberg
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`STATEMENT BY APPLICANT |.
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`PART B - FEE(S} TRANSMITTAL
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`Complete and send this form, together with applicable fee(s), by mail or fax, or via EFS-Weh.
`Bymail, send fo: Mail Siop ISSUE FEE
`Commissioner for Patents
`P.O. Box 1450
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`
`through 3 should be completed where
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`
`appropriate. AL further correspondence including the Patent. advance orders and nolfication of maimtenance fees will De mailed to the current correspondence address a3
`indicated unless corrected below or directed otherwise in Glock 1. by (a) specifying a@ new correspondence address: and/or (1) indicating a separate “PEL ADDRESS" for
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`CURRENT CORRUSPOSDENCE ADDRESS (Nore: Use lock | foram change of adresse
`
`CoreAD
`7500
`os
`3
`> 7
`ne
`BOOTH UDALL PULLER, PLC
`1255 W. Bio Salado Pkwy.
`1
`.
`Suite 215
`‘Tempe, AZ R528]
`
`
`
`APPLICATION NO.
`
`FILING: DATE
`
`FIRST NAMED INVENTOR
`
`ATTORSEY DOCKIGT WO
`
`CONTIRMATICEN SOL
`
`Jon Lundbere
`O4 30/201 8
`15/966,508
`TTL: OF INVENTION: COMPOSTTTIONS OF NTPRATIS ANT MUTHODS OF USE: THLREOD
`
`1255.10) CON BP
`
`2585
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`Note: A certificate of mailing can only be used for domestic mailings of ihe
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`ansittiss
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`U2 pucor pitted mane
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`APPLY. TYPE PUBLICATION FEE DVT|PREY. PAID ISSUE PEEENTITY STATUS ISSUE FEE DUE TOTAL PEE(S: DUE
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`DATE BV
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`REGULAR
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`SMALL.
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`S50)
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`$0.00
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`$0.00
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`5500
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`12/23/7020
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`
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`FRAZIER. BARBARA S
`
`167]
`
`424-7 18000
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`
`
`1. Changeof correspondence address or indication of "Fee Addvess” (37
`CER 1.363).
`J Change of correspondence address (or Change of Correspondence
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`LI "Hee Address" indication tor "Boe Address” (Indication Form
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`apo
`”
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`Saya lls
`J Sootn Jdall Salles, PLC
`be
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`3
`.
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`AGAR TataLT
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`ASSOCKING,
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`LDindividual Ga Copporation or olher private group entity LI Government
`Please check the appropriate assigace category or categories (will sot be printed on the patent):
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`EI tleetronic Payarent via HPS-Web
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` LJ Applicant changing to regular undiscounted Fee status.
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`§. Change in Entity Status (from status iadicated above}
`LJ Applicant certifying micro entity status. See 37 CPR 1.29
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`J Applicant asserting small entity status. See 37 CUR [27
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`NOTE: Absent a valid certification of Micro Entity Status (see forms PTO/SB/ISA and 5B).issuv
`fer payatent in the micro entity amount will sot be accepted at the risk of application abandonateni.
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`Electronic Patent Application Fee Transmittal
`
`Application Number:
`
`15966508
`
`
`
`Filing Date: 30-Apr-2018
`
`Title of Invention:
`
`COMPOSITIONS OF NITRATES AND METHODS OF USE THEREOF
`
`
`
`First Named Inventor/Applicant Name:
`
`Jon Lundberg
`
`Attorney Docket Number:
`
`1255.101 CON BP
`
`Filed as Small Entity
`
`Filing Fees for Utility under 35 USC 171{a}
`
`
`
`
`
`
`
`
`Sub-Total in
`Fee Code Quantity AmountDescription USD{$}
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`
`
`
`
`Basic Filing:
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`Pages:
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`
`Claims:
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`Miscellaneous-Filing:
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`Petition:
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`Patent-Appeals-and-Interference:
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`Electronic AcknowledgementReceipt
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`Application Number:
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`15966508
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`International Application Number:
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`Confirmation Number:
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`Title of Invention:
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`COMPOSITIONS OF NITRATES AND METHODS OF USE THEREOF
`
`
`
`First Named Inventor/Applicant Name:
`
`Jon Lundberg
`
`
`
`Filer: Pacer K. Udall/Sheri Higgins
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`Filer Authorized By:
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`Pacer K. Udall
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`Attorney Docket Number:
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`1255.101 CON BP
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`Filing Date: 30-APR-2018
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`Time Stamp:
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`Application Type:
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`Utility under 35 USC 111[(a}
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`Paymentinformation:
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`CARD
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`RAM confirmation Number
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`£202090H39208866
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`503545
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`Sheri Higgins
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`The Director of the USPTO is hereby authorized to charge indicated fees and credit any overpaymentas follows:
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`37 CFR 1.16 (National application filing, search, and examination fees)
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`37 CFR 1.19 (Document supply fees)
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`37 CFR 1.20 (Post Issuance fees)
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`37 CFR 1.21 (Miscellaneous fees and charges)
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`File Listing:
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`Document Description
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`File Size(Bytes}/
`Multi
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`Number Message Digest|Part /.zip| (if appl.} P
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`120408
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`Issue Fee Payment (PTO-85B)
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`IssueFeeTrans_101CONBPpdf F2Sd4 oOoahloe (OMGS6422073799
`6d
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`Warnings:
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`Corrected Notice of Allowance - Correction of Issue Fee Amount
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`Due to a technical problem, the Notice of Allowance and Fee(s} Duc mailed m this application specified an incorrect fee amount (the
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`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENTOF COMMERCE
`United States Patent and Trademark Office
`Adkiress: COMMISSIONER POR PATIENTS
`PA. Box 1450
`Alexanlnia, Virginia 77414-1450
`AAA MPHgtk
`
`CORRECTED
`NOTICE OF ALLOWANCE AND FEE(S) DUE
`
`BOOTH UDALL FULLER, PLC
`1255 W. Rio Salado Pkwy.
`ne
`Tempe, AZ 85281
`
`FRAZIER. BARBARA §
`
`
`161]
`
`BATE MATLIED: 09/23/2020
`
`APPLICATION NO.
`
`FILING: DATE
`
`CONTIRMATICEN SOL
`
`FIRST NAMED INVENTOR
`
`ATTORSEY DOCKIGT WO
`
`Jon Lundbere
`O4 30/201 8
`15/966,508
`TITLE OF INVENTION: COMPOSITIONS OF NITRATES AND METHODS OF USI THEREOD
`
`1255.10) CON BP
`
`2585
`
`
`
`
`
`ENTITY STATUS PUBLICATION FEE DVT|PREY. PAID ISSUE PEEISSUE FEE DUE TOTAL PEE(S: DUE DATE BV
`
`
`
`
`
` APPLY. TYPE
`
`REGULAR
`
`SMALL.
`
`S50)
`
`$0.00
`
`$0.00
`
`5500
`
`12/23/7020
`
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`Mail Stop ISSUE PEE unless advised to the contrary.
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`IMPORTANT REMINDER: Maintenance fees are due in utility patents issuing on applications filed on or after Dec. 12, 1980. It is
`patentee's responsibilily to ensure timely payment of maintenance fees when due, More information is available at
`www.uspto.gov/PatentMaintenanceFees.
`
`PTOD-85 (Rev. G2/1 1)
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`Page 2 of4
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`Page 9 of 562
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`Page 9 of 562
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`

`PART B - FEE(S} TRANSMITTAL
`
`Complete and send this form, together with applicable fee(s), by mail or fax, or via EFS-Weh.
`Bymail, send fo: Mail Siop ISSUE FEE
`Commissioner for Patents
`P.O. Box 1450
`Alexandria, Virginia 22313-1456
`
`By fax, send to:
`
`(571)-273-2885
`
`
`through 3 should be completed where
`INSTRUCTIONS: This form should be used for transmitting the ISSTL Gil and PUBLICATION Bilis (if required), Blocks |
`
`appropriate. AL further correspondence including the Patent. advance orders and nolfication of maimtenance fees will De mailed to the current correspondence address a3
`indicated unless corrected below or directed otherwise in Glock 1. by (a) specifying a@ new correspondence address: and/or (1) indicating a separate “PEL ADDRESS" for
`maintenance feo notifications,
`
`CURRENT CORRUSPOSDENCE ADDRESS (Nore: Use lock | foram change of adresse
`
`CoreAD
`7500
`os
`3
`> 7
`ne
`BOOTH UDALL PULLER, PLC
`1255 W. Bio Salado Pkwy.
`1
`.
`Suite 215
`‘Tempe, AZ R528]
`
`
`
`APPLICATION NO.
`
`FILING: DATE
`
`FIRST NAMED INVENTOR
`
`ATTORSEY DOCKIGT WO
`
`CONTIRMATICEN SOL
`
`Jon Lundbere
`O4 30/201 8
`15/966,508
`TTL: OF INVENTION: COMPOSTTTIONS OF NTPRATIS ANT MUTHODS OF USE: THLREOD
`
`1255.10) CON BP
`
`2585
`
`Note: A certificate of mailing can only be used for domestic mailings of ihe
`Veets}> Transmittal. This ceriificate cannot be used for any other accompanying
`papers. Lach additional paper, such as an assignment or formal drawing, must
`ave its own cerificate of mailing or ransmission.
`Certificate of Mailing or Transmission
`:
`)
`ansittiss
`Therebycertify that this Vee(s) Transmittal is being deposited with the United
`States Postal Service with sufficient postage forfirst class mail ia an envelope
`addressed to the Mail Stop [ISSUE iin address above. or bein2 transmitted to
`the USPTO via LLS-Web or by Pacsimile to (571) 273-2885. on the date
`indicated below,
`
`U2 pucor pitted mane
`
`(Sigurature +
`(Dkatet
`
`
`
`
`
`
`
`
`
`
`
`APPLY. TYPE PUBLICATION FEE DVT|PREY. PAID ISSUE PEEENTITY STATUS ISSUE FEE DUE TOTAL PEE(S: DUE DATE BV
`
`
`
`REGULAR
`
`SMALL.
`
`S50)
`
`$0.00
`
`$0.00
`
`5500
`
`12/23/7020
`
` EXAMINER
`
`PRAZIER. BARBARA S
`
`161]
`
`424-718000
`
`ART UNIT
`
`CLASS-SUBCLASS
`
`
`
`1. Changeof correspondence address or indication of "Fee Addvess” (37
`ay
`TH
`CER 36%),
`J Change of correspondence address (or Change of Correspondence
`Address form PTO/Si5/122) attached.
`LY “Fee Address" indication (or "Bee Address" Indication form
`PTOMSBAI7: Rev 03-00 of more recent) atlached. Use of a Costomer
`Number ts required.
`3, ASSIGNNAME AND RUSIDUNCE DATA TO BE PRINTED ON THE PATIENT(print or type)
`the document must have been
`TF an assignee is identified below.
`PLEASE NOTE: Unless an assigace is identified below, ao assignee data will appear on the patent.
`previously recorded. or filed For recordation, as set Forth in 37 CPR 3.1) and 37 CPR 3.814). Completion of this form is NOTa subsitiaie For filing an assignment.
`(A) NAMI OF ASSIOALL:
`(B) RESIDENCI: (CITY and STATE OR COLNTRY)
`
`
`
`2. For printing on ihe patent front page, list
`.
`:
`(1) The names of up to 3 registered patent attorneys
`ow agents OR. alternatively.
`(2) The name of a single firm (having as a member a
`registered atlorney or agent) and the naates of up to
`2 registered patent atiorneys or agents. fno nant is
`listed, no name will be printed,
`
`]
`2
`
`3
`.
`
`individual Copporation or olher private group entity LI Government
`Please check the appropriate assigace category or categories (will sot be printed on the patent):
`da. Bees submitted:
`issue Ber
`Publication Boe (if required)
`LlAdvance Order - # of Copies
`
`db, Method of Payinent: (Please first reapply any previously puid fee shown above}
`Electronic Payatent via EPS-Web
`( Eaclosed check
`LI) Non-electronic payment by credit card (Atach Form PTO-2038)
`The Director is hereby authorized to charge the required fee(s}, any deficiency, or credit any overpayment to Deposit Account No.
`
` LJ Applicant changing to regular undiscounted Fee status.
`
`§. Change in Entity Status (from status iadicated above}
`LJ Applicant certifying micro entity status. See 37 CPR 1.29
`
`J Applicant asserting small entity status. See 37 CUR [27
`
`NOTE: Absent a valid certification of Micro Entity Status (see forms PTO/SB/ISA and 5B).issuv
`fer payatent in the micro entity amount will sot be accepted at the risk of application abandonateni.
`NOTH: (f the application was previously under microcatty status, checking this box will be taken
`to be a notification of loss of entitlement to micre cnlitystatus.
`NOTE: Checking this box will be taken to be a potificaiion of loss of entitlement to small or micro
`entity siatus, as applicable.
`NOTE: This form must be signed in accordance with 47 CER Dal and 1.33. See 37 CER 14 for siznature requirements and certifications.
`
`
`
`Authorized Sienature
`
`Typedof printed name
`
`Date
`
`Registration No.
`
`PYTOL-85 Part B (08-18) Approved for use through 01/3 1/2020
`
`Page 3 of4
`OMB 0651-0033
`
`Page 10 of 562
`U.S. Patent and Trademark Office: LS, DUPARTMES T Ob COMMURGCH
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`Page 10 of 562
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`

`

`
`
`=z
`@
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENTOF COMMERCE
`United States Patent and Trademark Office
`Adkiress: COMMISSIONER POR PATIENTS
`PA. Box 1450
`Alexanlnia, Virginia 77414-1450
`AAA MPHgtk
`
`
`
`HILDNG DATE ATTORNEY DOCKET SO,|CONEIRMATION NO.FIRST NAMED INVENTOR
`
`
`
` APPLICATION NO,
`
`15/966.508
`
`04/30/2018
`
`Jon Lundberg
`
`1255.10] CON BP
`
`2585
`
`Addad
`
`FRAN)
`
`(AW?Ay
`
`BOOTH UDALL FULLER, PLC
`1255 W. Rio Salado Pkwy.
`Sutle 214
`Tempe, AZ 85281
`
`EXAMINER
`
`FRAZIER. BARBARA §
`
`
`ART UNIT
`161]
`
`PAPER NUMBER
`
`BATE MATLIED: 09/23/2020
`
`Determination of Patent Term Adjustment under 35 U.S.C, 154 (b)
`{Applications filed on or after May 29, 2000)
`
`The Office has discontinued providing a Patent Term Adjustment (PTA) calculation with the Notice of Allowance.
`
`Section I(h)(2} of the AIA Technical Corrections Act amended 35 U.S.C. 154{b}3}(B)(i} to eliminate the
`requirement
`that
`the Office provide a patent
`term adjustment determination with the notice of allowance. See
`Revisions to Patent Term Adjustment, 78 Fed. Reg. 19416, 19417 (Apr. 1, 2013). Therefore, the Office is no longer
`providing an initial patent term adjustment determination with the notice of allowance. The Office will continue to
`provide a patent
`term adjustment determination with the Issue Notification Letter that
`is mailed to applicant
`approximately three weeks prior to the issue date of the patent, and will include the patent term adjustment on the
`patent. Any request for reconsideration of the patent term adjustment determination (or reinstatement of patent term
`adjustment} should follow the process outlined in 37 CFR 1.705.
`
`Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the Office of
`Patent Legal Administration at (571)-272-7702. Questions relating to issue and publication fee payments should be
`directed to the Customer Service Centerof the Office of Patent Publication at 1-{888}-786-0101 or (571)-272-4200.
`
`PTOL-85 (Rev. 02/11)
`
`Page 4 of 4
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`Page 11 of 562
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`

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