Sailaja Machiraju
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`Paragon BioTeck, Inc.
`4640 SW Macadam Ave., Ste 80
`Portland, OR 97239
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`EDUCATION
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`M.S., Organic Chemistry, BAM University, India
`Graduation date: 2002
`Research Focus: Synthetic organic chemistry, medicinal chemistry and ophthalmic
`pharmaceutical research and development. In particular, I pursued synthesis of various new chemical
`entities (NCEs), biologically active pharmaceuticals and active pharmaceutical ingredients (APIs), all of
`which had potential utility as agrochemicals or pharmaceuticals. Finally, I was involved in design,
`synthesis, process optimization, identification, and characterization of pharmaceutical entities using
`various synthetic and analytical chemistry techniques.
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`RESEARCH EXPERIENCE
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`Senior Research Associate
`2013-Present
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`Paragon BioTeck, Inc., Portland Oregon
`• Scientific lead for research and development of ophthalmic pharmaceuticals.
`• Management of internal and outsourced clinical research projects.
`• Coordination of the various scientific groups with respect to quality assurance and
`implementation of good laboratory practices (GLP).
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`Research Associate
`2006-2009
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`Dr. Reddy’s Laboratories Ltd., Hyderabad, India
`• Synthesis, purification, characterization and process optimization of new molecular
`entities and active pharmaceutical ingredients.
`• Performed research activities under current good manufacturing protocols (cGMP).
`• Optimized multi-step synthetic routes using modern synthetic organic chemistry
`methods.
`• Developed synthetic organic methods for compounds containing various pharmacologically
`active natural products and APIs that had anti-diabetic and anti-cancer activity.
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`Research Associate
`2002-2005
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`GVK Bio Sciences Ltd., Hyderabad, India
`• Research and development of NCEs and biologically active compounds with potential utility as
`agrochemicals.
`• Design & development of various synthetic routes for biologically active compounds containing
`various pharmacologically relevant heterocycles, such as benzofuranones, piperazines,
`thiophenes and pyrazoles.
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`PARAGON - EXHIBIT 2036
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`• Synthesis, purification, characterization and process optimization using various pharmaceutical
`and analytical method.
`• Regularly employed chromatographic techniques such as column chromatography, Jones
`chromatography, medium pressure liquid chromatography (MPLC), and preparative thin-layer
`chromatography (TLC).
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