Office Address:
`
`Education:
`
`Curriculum Vitae
`
`Maureen D. Donovan, Ph.D.
`
`University of Iowa
`College of Pharmacy
`115 S. Grand Ave
`Iowa City, IA 52242
`maureen-donovan@uiowa.edu
`319-335-9697
`
`University of Minnesota College of Pharmacy
`Minneapolis, Minnesota
`Bachelor of Science in Pharmacy, 1983
`
`University of Michigan College of Pharmacy
`Horace H. Rackham School of Graduate Studies
`Ann Arbor, Michigan
`Ph.D. (Pharmaceutics), 1989
`
`PROFESSIONAL EXPERIENCE
`
`2008-present
`
`Professor
`Department of Pharmaceutical Sciences and Experimental Therapeutics
`University of Iowa College of Pharmacy
`Iowa City, IA
`
`2016-2018
`
`2013-2019
`
`2008-2013
`
`1996-2008
`
`1989-1996
`
`Department of Health and Human Physiology
`College of Liberal Arts and Sciences
`University of Iowa (2019-2020)
`
`Associate Dean for Undergraduate Education
`College of Pharmacy
`University of Iowa
`Iowa City, IA
`
`Division Head
`Division of Pharmaceutics and Translational Therapeutics
`University of Iowa College of Pharmacy
`Iowa City, IA
`
`Associate Professor
`University of Iowa College of Pharmacy
`Division of Pharmaceutics
`Iowa City, IA
`
`Assistant Professor
`University of Iowa College of Pharmacy
`Division of Pharmaceutics
`Iowa City, IA
`
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`Visiting Scholar
`SmithKline Beecham Pharmaceuticals
`King of Prussia, PA
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`1991
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`
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`1986-88
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`
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`ADDITIONAL POSITIONS AND MEMBERSHIPS
`
`2011-2020
`
`Staff Pharmacist
`Clark Professional Pharmacy
`Ypsilanti, MI
`
`
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`
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`Honorary Visiting Professor, Tongji School of Pharmacy, Tongji Medical
`University, Wuhan, China
`
`Member, Environmental Health Sciences Research Center, University of Iowa
`
`2010-present
`
`2009-10
`
`PUBLICATIONS
`
`Thesis
`
`Donovan, Maureen D. The Molecular Weight Permeability Dependence of the Absorption of
`Polyethylene Glycols in the Nasal and Gastrointestinal Mucosa and Its Correlation to Size
`Dependent Diffusion. Ph.D. Thesis, The University of Michigan, 1989.
`
`Publications
`
`1. Miller SC and Donovan MD. Effect of Poloxamer Gels on the Miotic Activity of Pilocarpine
`
`Nitrate in Rabbits. Int. J. Pharm. 12, 147-152, 1982.
`
`2. Donovan MD, Flynn GL, Amidon GL. The Molecular Weight Dependence of Nasal
` Absorption: The Effect of Absorption Enhancers. Pharm. Res. 7, 808-815, 1990.
`PMID 2235878. doi:10.1023/a:1015904730599.
`
`
`
`Member, Nanoscience and Nanotechnology Institute at the University of Iowa.
`
`
`3. Donovan MD, Flynn GL, Amidon GL. Absorption of Polyethylene Glycols 600 through 2000:
`
`The Molecular Weight Dependence of Gastrointestinal and Nasal Absorption. Pharm. Res.
`
`7, 863-868, 1990. PMID 2235883. doi: 10.1023/a:1015921101465.
`
`4. Donovan MD and Zhou M. Drug Effects on In Vivo Nasal Clearance in Rats. Int. J. Pharm.
`116, 77-86, 1995.
`
`
`5. Chung FY and Donovan MD. Pre-systemic Bradykinin Metabolism in Rat and Sheep Nasal
` Homogenates. J. Pharm. Sci. 84, 794-798, 1995. PMID: 7562426.
`doi:10.1002/jps.2600840703.
`
`6. Chung FY and Donovan MD. Bradykinin Metabolism in Rat and Sheep Nasal Secretions.
`
`J. Pharm. Sci. 84, 829-834, 1995. PMID: 7562432. doi: 10.1002/jps.2600840709.
`
`7. Bhat PG, Flanagan DR, Donovan MD. The Limiting Role of Mucus in Drug Absorption:
`
`Drug Permeation through Mucus Solution. Int. J. Pharm. 126, 179-187, 1995.
`
`8. Huang Y and Donovan MD. Microsphere Transport Pathways in the Rabbit Nasal Mucosa.
`
`Int. J. Pharm. Adv. 1, 298-309, 1996.
`
`9. Chung FY and Donovan MD. Nasal Pre-systemic Metabolism of Peptide Drugs:
`Substance P Metabolism in the Sheep Nasal Cavity. Int. J. Pharm. 128, 229-237, 1996.
`
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`10. Zhou M and Donovan MD. Recovery of the Nasal Epithelium following Laureth-9 Induced
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`Damage. Int. J. Pharm. 130, 93-102, 1996.
`
`11. Bhat PG, Flanagan DR, Donovan MD. Drug Diffusion through Cystic Fibrotic Mucus:
`
`Steady-State Permeation, Rheologic Properties, and Glycoprotein Morphology. J. Pharm.
`Sci. 85, 624-630, 1996. PMID: 8773960. doi: 10.1021/js950381s.
`
`
`12. Bhat PG, Flanagan DR, Donovan MD. Drug Binding to Gastric Mucus Glycoproteins. Int. J.
`Pharm. 134, 15-25, 1996.
`
`
`13. Zhou M and Donovan MD. Intranasal Mucociliary Clearance of Bioadhesive Polymer Gels.
`
`Int. J. Pharm. 135, 115-125, 1996.
`
`14. Nardviriyakul N, Wurster DE, Donovan MD. Determination of Diffusion Coefficients of
`
`Sodium p-Aminosalicylate in Sheep Nasal Membranes and Dialysis Membranes by Fourier
`
`Transform Infrared Horizontal Attenuated Total Reflectance Spectroscopy. J. Pharm. Sci.
`
`86, 19-25, 1997. PMID: 9002454. doi: 10.1021/js960314d.
`
`15. Chou K-J and Donovan MD. Distribution of Antihistamines into the CSF following Intranasal
` Delivery. Biopharm. Drug Disp. 18, 335-346, 1997. PMID: 9158881. doi: 10.1002/(sici)1099-
`081x(199705)18:4<335::aid-bdd22>3.0.co;2-w.
`
`
`16. Donovan MD and Huang Y. Large Molecule and Particulate Uptake in the Nasal Cavity:
` The Effect of Size on Nasal Absorption. Adv. Drug Deliv. Rev. 29, 147-155, 1998. PMID:
`10837585. doi: 10.1016/s0169-409x(97)00066-5.
`
`
`17. Chou K-J and Donovan MD. Distribution of Local Anesthetics into the CNS following
`
`Intranasal Administration. Int. J. Pharm. 168, 137-145, 1998.
`
`18. Chou K-J and Donovan MD. Lidocaine Distribution into the CNS following Nasal and
`
`Arterial Delivery: A Comparison of Local Sampling and Microdialysis Techniques. Int. J.
`Pharm. 171, 53-61, 1998.
`
`
`19. Khanvilkar K, Donovan MD, Flanagan DR. Drug Transfer through Mucus. Adv. Drug
`Deliv. Rev 48, 173-193, 2001. PMID: 11369081. doi: 10.1016/s0169-409x(01)00115-6.
`
`
`20. Donovan MD Sex and Racial Differences in Pharmacologic Response: Effect of Route of
`
`Administration and Drug Delivery System on Pharmacokinetics. J. Womens Health 14(1),
`
`30-37, 2005. PMID: 15692275. doi: 10.1089/jwh.2005.14.30.
`
`21. Kandimalla K. and Donovan M.D. Carrier Mediated Transport of Chlorpheniramine and
`Chlorcyclizine across Bovine Olfactory Mucosa: Implications on Nose-to-Brain Transport.
`J. Pharm. Sci. 94, 613-624, 2005. PMID: 15666293. doi: 10.1002/jps.20284.
`
`
`22. Sinn PL, McCray PB, Donovan MD, Shah AJ. Viscoelastic Gel Formulations Enhance
`Airway Epithelial Gene Transfer with Viral Vectors. Am. J. Resp. Cell. Mol. Biol. 32, 404-
`410, 2005. PMID: 15695737. doi: 10.1165/rcmb.2004-0410OC.
`
`
`23. Chemuturi NV, Hayden P, Klausner M, and Donovan MD. Comparison of Human
`Tracheal/bronchial Epithelial Cell Cultures (EpiAirway) and Bovine Nasal Respiratory
`Explants for Nasal Drug Transport Studies. J. Pharm. Sci. 94, 1976-1985, 2005.
`PMID: 16052562. doi: 10.1002/jps.20404.
`
`
`24. Kandimalla K. and Donovan M.D. Localization and Differential Activity of P-glycoprotein in
` the Bovine Olfactory and Nasal Respiratory Mucosae. Pharm. Res. 22, 1121-1128, 2005..
`PMID:16028013. doi:10.1007/s11095-005-5420-3.
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`25. Kandimalla K. and Donovan M.D. Transport of Hydroxyzine and Triprolidine Across Bovine
` Olfactory Mucosa: Role of Passive Diffusion in the Direct Nose-to-Brain Uptake of Small
` Molecules. Int.J. Pharm. 302, 133-144, 2005. PMID: 16105724.
`doi: 10.1016/j.ijpharm.2005.06.012.
`
`
`26. Chemuturi NV and Donovan MD. Metabolism of Dopamine Hydrochloride by the Nasal
`
`Mucosa. J. Pharm. Sci. 95, 2507-2515, 2006. PMID: 16917843. doi:10.1002/jps.20724.
`
`27. Chemuturi NV, Haraldsson JE, Prisinzano TP, and Donovan MD. Role of Dopamine
`Transporter (DAT) in Dopamine Transport Across the Nasal Mucosa. Life Sci. 79, 1391-
`1398, 2006. PMID:16733058. doi: 10.1016/j.lfs.2006.04.021.
`
`
`28. Donovan MD. Nose to Brain Drug Delivery: An Optimistic Pessimist’s Analysis. In
`Respiratory Drug Delivery 2006. Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ (Eds).
`Davis Healthcare International Publishers, River Grove IL. 2006, p. 239-248.
`
`
`29. Shah AJ and Donovan MD. Rheological Characterization of Bioadhesive Polysaccharide
`Polymers with Reduced Mucociliary Clearance for Intranasal Delivery. AAPS
`PharmSciTech, 8(2): E40-E47, 2007. doi: 10.1208/pt0802032
`
`
`30. Shah AJ and Donovan MD. Formulating Gels for Decreased Mucociliary Transport Using
`Rheologic Properties: Polyacrylic Acids. AAPS PharmSciTech, E48-E53, 2007.
`doi: 10.1208/pt0802033
`
`
`31. Foo M-Y, Cheng Y-S, Su W-C, and Donovan MD. The Influence of Spray Geometry on
`Intranasal Deposition and Distribution. J. Aerosol Med. 20 (4), 495-508, 2007.
`PMID:31809854. doi: 10.1089/jam.2007.0638.
`
`
`32. Chemuturi NV and Donovan MD. The Role of Organic Cation Transporters in Dopamine
`Transport Across Olfactory and Nasal Respiratory Tissues. Mol. Pharmaceutics. 4(6), 936–
`942, 2007. PMID: 17892261. doi:10.1021/mp070032u.
`
`
`33. Abbas AO, Donovan MD, Salem A. Technical Aspects of Formulating Poly (lactide-co-
`glycolide). J. Pharm. Sci., 97, 2448-2467, 2008. PMID: 17918737. doi: 10.1002/jps.21215.
`
`
`34. Zhang H, Schmidt M, Murry DJ, Donovan MD. Permeation and Systemic Absorption of R-
`and S- Baclofen across the Nasal Mucosa. J. Pharm. Sci.,100. 2717-2723, 2011. PMID:
`21283988. PMCID: 21283988. doi: 10.1002/jps.22499.
`
`
`35. Zhang H, Prisinzano T, and Donovan MD. Permeation and Metabolism of Cocaine in the
`Nasal Mucosa. Eur. J. Drug Metab. Pharmacokinet. 37(4), 255-262, 2012. PMID: 22351075.
`doi:10.1007/s13318-012-0085-x.
`
`
`36. Zhang H, Lin C-W, Donovan MD. Correlation between Nasal Membrane Permeability and
` Nasal Absorption Rate. AAPS PharmSciTech 14(1), 60-63, 2013. PMID: 23225081.
`PMCID: PMC3581654. doi:10.1208/s12249-012-9884-2.
`
`
`37. Lack WD, Fredricks D, Petersen E, Donovan MD, George M, Nepola J, Smucker J, Fermino
`JE. The Effect of Low Dose Aspirin on Bone Healing in a Rabbit Ulna Osteotomy Model. J
`Bone Joint Surg. Am. 95(6), 488-96, 2013. PMID: 23407637. doi: 10.2106/JBJS.L.00462.
`
`
`38. Al-Ghabeish M, Scheetz T, Assem M, Donovan MD. Microarray Determination of Expression
`of Drug Transporters in Humans and Animal Species Used in the Investigation of Nasal
`Absorption. Mol. Pharmaceutics. 12(8), 2742-2754, 2015. PMID:26106909.
`PMCID:PMC4671632. doi:10.1021/acs.molpharmaceut.5b00103.
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`39. Dhamankar V, Assem M, Donovan MD. Gene Expression and Localization of Major
`Cytochrome P450 Metabolizing Isoforms in Bovine Nasal Olfactory and Respiratory Mucosa.
`Inhal. Tox. 16, 1-11, 2015. PMID: 26572092. PMCID: PMC4970319.
`doi: 10.3109/08958378.2015.1066903.
`
`
`40. Xu J, Li G, Wang Z, Si L, Huang J, Donovan MD. The Role of L-type Amino Acid
`Transporters in the Uptake of Glyphosate across Mammalian Epithelial Tissues.
`Chemosphere. 145, 487-494, 2016. PMID: 26701683.
`doi: 10.1016/j.chemosphere.2015.11.062.
`
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`41. Dhamankar V and Donovan MD. Modulating Nasal Mucosal Permeation Using Metabolic
`Saturation and Enzyme Inhibition Techniques. J. Pharm. Pharmacol. 69, 1075-1083, 2017.
`PMID: 28542812. doi: 10.1111/jphp.12749.
`
`
`42. Ponto LLB, Walsh S, Huang J, Mundt C, Thede-Reynolds K, Watkins GL, Sunderland J,
`Donovan MD. Pharmacoimaging of Blood-Brain Barrier Permeable (FDG) and Impermeable
`(FLT) Substrates after Intranasal (IN) Administration. AAPS J. 20(1):15, 2017.
`PMID: 29218424. PMCID: PMC5798226. doi: 10.1208/s12248-017-0157-6.
`
`
`43. Ponto LLB, Huang J, Walsh S, Acevedo MR, Mundt C, Sunderland J, Donovan MD.
`Demonstration of Nucleoside Transporter Activity in the Nose-to-Brain Distribution of
`[18F]fluorothymidine Using PET Imaging. AAPS J. 20(1):16, 2017. PMID: 29218445.
`PMCID: PMC5814119. doi: 10.1208/s12248-017-0158-5.
`
`
`44. Sawant N and Donovan MD. In Vitro Assessment of Spray Deposition Patterns in a Pediatric
`(12 Year-Old) Nasal Cavity Model. Pharm. Res. 35, Article 108, 2018. PMID: 29582159.
`doi: 10.1007/s11095-018-2385-6.
`
`
`45. Awasthi R, An Guohua, Donovan MD, Ponto LB. Relating Observed Psychoactive Effects to
`the Plasma Concentration of ∆9-tetrahydrocannibinol (THC) and Active Metabolite: An Effect-
`Compartment Modeling Approach. J. Pharm. Sci. 107, 745-755, 2018. PMID: 28942005.
`doi: 10.1016/j.xphs.2017.09.009.
`
`
`
`46. Foo MW, Sawant N, Overholtzer E, Donovan MD. A Simplified Geometric Model to Predict
`Nasal Spray Deposition in Children and Adults. AAPS PharmSciTech. 19(7):2767-2777,
`2018. PMID: 29948982. doi: 10.1208/s12249-018-1031-2.
`
`
`47. Al Bakri W, Donovan MD, Cueto M, Wu Y, Orekie C, Yang Z. Overview of Intranasally
`Delivered Peptides: Key Considerations for Pharmaceutical Development. Exp. Opinion
`Drug Deliv. 15, 991-1005, 2018. PMID: 30173579. doi: 10.1080/17425247.2018.1517742.
`
`
`48. Meruva S and Donovan MD. Effects of Drug-Polymer Interactions on Tablet Properties
`During the Development of Abuse-Deterrent Dosage Forms. AAPS PharmSciTech, Jan 28,
`20(3):93, 2019. PMID 30690657. doi: 10.1208/s12249-018-1221-y.
`
`
`49. Meruva S and Donovan MD. Polyethylene Oxide (PEO) Molecular Weight Effects on Abuse-
`Deterrent Properties of Matrix Tablets. AAPS PharmSciTech. 21(1):28, 2019. PMID
`31858320. https://doi.org/10.1208/s12249-019-1565-y.
`
`
`50. Meruva S, Rezaei L, Thool P, Donovan MD. Use of Drug Release Testing to Evaluate the
`Retention of Abuse-Deterrent Properties of Polyethylene Oxide Matrix Tablets. AAPS
`PharmSciTech. Oct 6;21(7):270, 2020. PMID: 33025237. doi: 10.1208/s12249-020-01804-y.
`
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`51. Al Barki M and Donovan MD. Bigger or Smaller?: Size and Loading Effects on Nanoparticle
`Uptake Efficiency in the Nasal Mucosa. AAPS PharmSci Tech. 21(8):294, 2020. PMID:
`33099728. PMCID: PMC7943034. doi: 10.1208/s12249-020-01837-3.
`
`
`52. Bejgum G, Donovan MD. Uptake and Transport of Ultrafine Nanoparticles (Quantum Dots) in
`the Nasal Mucosa. Mol. Pharmaceutics. 18(1); 429-440, 2021. PMID:33346666.
`doi.org/10.1021/acs.molpharmaceut.0c01074.
`
`
`53. Al Khafaji A, Donovan MD. Endocytic Uptake of Solid Lipid Nanoparticles by the Nasal
`Mucosa. Pharmaceutics 13, 761, 2021. PMID:34065558 PMCID:PMC8161025
`https://www.mdpi.com/1999-4923/13/5/761.
`
`
`54. Vasa DM, Bakri Z, Donovan MD, O’Donnel LA, Wildfong PLD. Evaluation of Ribavirin-
`Poloxamer Microparticles for Improved Intranasal Absorption. Pharmaceutics 13,1126, 2021.
`PMCID: PMC8399989 PMID: 34452087 doi.org/10.3390/pharmaceutics13081126.
`
`
`55. Chede LS, Wagner B, Buettner G, Donovan MD. Electron Spin Resonance Evaluation of
`Buccal Membrane Fluidity Alterations by Sodium Caprylate and L-Menthol. Int J Mol Sci.
`22(19) 10708, 2021. PMID:34639049 PMCID:PMC8509842.
`http://doi.org/10.3390/ijms221910708.
`
`
`56. Rezaei L, Meruva S, Donovan MD. Effect of Manufacturing Process on the Retention of
`Abuse-Deterrent Properties of PEO-Matrix Tablets. AAPS PharmSci Tech 23(1):38, 2022.
`PMID:34961912. https://doi.org/10.1208/s12249-021-02169-6
`
`
`57. Albarki MA, Donovan MD. Uptake of Cationic PAMAM-PLGA Nanoparticles by the Nasal
`Mucosa. Sci Pharm. 90(4), 72; 2022. https://doi.org/10.3390/scipharm90040072
`
`
`58. Chede LS, Donovan MD. Achieving Therapeutic Drug Concentrations in the Esophagus
`Using Bioadhesive Dosage Forms. Int J Pharm. 642, 123115, 2023.
`https://doi.org/10.1016/j.ijpharm.2023.123115
`
`
`Other Publications
`
`1. Donovan MD. Rifampin Stability Monograph in Chemical Stability of Pharmaceuticals. A
`Handbook for Pharmacists 2nd Edition. Connors KA, Amidon GL, and Stella VJ, John
`
` Wiley & Sons, New York, NY 1986.
`
`2. Amidon GL, Sinko PJ, Donovan MD. "Oral Absorption of Peptide and Peptide-Type Drugs:
`
`Problems and Prospects." in Peptides, Theoretical and Practical Approaches to Their
`Delivery. Capsugel Symposia Series, Greenwood, SC Capsugel Library, 1992.
`
`
`3. Donovan MD. Gender Equity in Faculty Hiring and Retention in The Dean's Compass:
`Practical Advice for Achieving Excellence, P. Chase, B. Hayes, V. Yanchik (Eds). AACP
`2007.
`
`
`4. Donovan MD. Graduate Education in Colleges of Pharmacy in The Dean's Compass:
`Practical Advice for Achieving Excellence, P. Chase, B. Hayes, V. Yanchik (Eds). AACP
`2007.
`
`
`BOOK CHAPTERS
`
`Donovan MD and Flanagan DR. “Bioavailability of Disperse Dosage Forms” in Pharmaceutical
`Dosage Forms: Disperse Systems Lieberman HA, Rieger MM, and Banker GS (Eds). Marcel
`Dekker, New York, 1995.
`
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`Donovan MD “The Effect of Route of Administration and Distribution on Drug Action” in Modern
`Pharmaceutics (5th Ed). A.T. Florence and J. Siepmann (Eds), CRC Press, Boca Raton, FL, 2009
`
`Donovan MD. “The Feminine World of Drug Delivery. On Female Needs and Delivery of Drugs
`Vaginally” in Physical and Biophysical Foundations of Pharmacy Practice. Issues in Drug
`Delivery. GL Flynn and MS Roberts. Michigan Publishing, Ann Arbor, MI 2015.
`
`Donovan MD, Foo A, Sawant N. Aerosol Delivery to the Nasal Cavity – A Tortuous Pathway to
`Efficacy. In: Dhand, R, editor. Textbook of Aerosol Medicine. Knoxville(TN): International Society
`of Aerosols in Medicine; 2015. p.e1-40. Available from: www.isam.org.
`
`
`PATENTS
`
`“Formulation and method for treating neoplasms by inhalation” M.E. Placke, A.R. Imondi, M.J.
`Brooker, J.E. Frye, P.K. Shah, D.R. Flanagan, M.D. Donovan US 6,348,209B2. (12/30/96).
`
`“RNA interference in respiratory epithelial cells” PB McCray, BL Davidson, A Fischer, HP Jia, MD
`Donovan. US 7,297,786 (11/20/07).
`
`
`ABSTRACTS
`
`"Poloxamer Gels for Ophthalmic Drug Delivery" Maureen D. Donovan and Susan C. Miller
`University of Minnesota/3M Research Poster Session St. Paul, MN December 15, 1982.
`
`"Evaluation of a Pilocarpine Nitrate Ophthalmic Gel" Maureen D. Donovan and Susan C. Miller
`Rho Chi Vistas in Pharmacy Program Kansas City, MO March 4-5, 1983.
`
`"Molecular Weight Permeability Dependence in the Nasal and Gastrointestinal Mucosa" Maureen
`D. Donovan, Gordon L. Flynn and Gordon L. Amidon American Association of Pharmaceutical
`Scientists 2nd National Meeting Boston, MA June 5-12, 1987. Pharm. Res. 4, S38, 1987.
`
`"The Effect of Absorption Adjuvants on the Molecular Weight Permeability Profile of Polyethylene
`Glycols in the Nasal Mucosa" Maureen D. Donovan, Gordon L. Flynn and Gordon L. Amidon
`American Association of Pharmaceutical Scientists 3rd National Meeting Orlando, FL October
`30-November 3, 1988. Pharm. Res. 5, S97, 1988.
`
`"Diffusion of Polyethylene Glycols 600-2000 through HEMA-MA Hydrogels" Maureen D.
`Donovan, Gordon L. Flynn and Gordon L. Amidon 16th International Symposium on Controlled
`Release of Bioactive Materials Chicago, IL August 6-9, 1989. Proceed. Int. Symp. Control. Rel.
`Bioactiv. Mater. 16, 213-214, 1989.
`
`"The Molecular Weight Permeability Dependence of Polyethylene Glycols through Mucin"
`Maureen D. Donovan, Gordon L. Flynn and Gordon L. Amidon American Association of
`Pharmaceutical Scientists 4th National Meeting Atlanta, GA October 22-26, 1989. Pharm. Res.
`6, S120, 1989.
`
`"Osmotic Effects on the Molecular Weight Permeability Profile of PEG in the Nasal Mucosa"
`Maureen D. Donovan, Michael Arndorfer and Kristen K. Swantz American Association of
`Pharmaceutical Scientists 6th National Meeting Washington D.C., November, 1991. Pharm.
`Res. 8, S129, 1991.
`
`"Assessment of Mucosal Damage following Intranasal Drug Administration" Maureen D.
`Donovan and Mengping Zhou American Association of Pharmaceutical Scientists 7th National
`Meeting San Antonio, TX November, 1992. Pharm. Res. 9, S207, 1992.
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`"Drug Binding Studies to BSA and Reconstituted Mucin by Diafiltration" Pavan G. Bhat, Douglas
`R. Flanagan and Maureen D. Donovan. American Association of Pharmaceutical Scientists
`Midwest Regional Meeting Chicago, IL May 17, 1993.
`
`"Proteolytic Activity in Nasal Secretions" Francis Y. Chung and Maureen D. Donovan. 20th
`International Symposium on Controlled Release of Bioactive Materials Washington D.C. July,
`1993. Proc. Int. Symp. Control. Rel. Bioactiv. Mater. 20, 1993.
`
`"The Effects of Drugs on Intranasal Clearance In Vivo" Mengping Zhou and Maureen D.
`Donovan. American Association of Pharmaceutical Scientists 8th Annual Meeting Orlando, FL,
`November 1993. Pharm. Res. 10, S196, 1993.
`
`"Distribution of Antihistamines into the CSF following Intranasal Delivery" Kang-Jye Chou and
`Maureen D. Donovan. American Association of Pharmaceutical Scientists 8th Annual Meeting
`Orlando, FL November, 1993. Pharm. Res. 10, S196, 1993.
`
`"Drug Interaction with and Permeation through Mucus" Pavan G. Bhat, Douglas R. Flanagan,
`Maureen D. Donovan. American Association of Pharmaceutical Scientists 8th Annual Meeting
`Orlando, FL November, 1993. Pharm. Res. 10, S259, 1993.
`
`"Bradykinin Degradation in Rat Nasal Secretions and Plasma" Francis Y. Chung and Maureen D.
`Donovan. American Association of Pharmaceutical Scientists Midwest Regional Meeting
`Chicago, IL May, 1994.
`
`"Comparison of Drug Permeation Rates through the Nasal Mucosa of Three Animal Species"
`Hsiao-Hui Wu, Peichung Kuo, and Maureen D. Donovan. American Association of
`Pharmaceutical Scientists Midwest Regional Meeting Chicago, IL May, 1994.
`
`"Pre-Systemic Metabolism of Bradykinin and Substance P in the Nasal Mucosa" Francis Y.
`Chung and Maureen D. Donovan. American Association of Pharmaceutical Scientists 9th Annual
`Meeting San Diego, CA November, 1994. Pharm. Res. 11, S205, 1994.
`
`"The Influence of Formulation Viscosity on Intranasal Clearance" Mengping Zhou and Maureen
`D. Donovan. American Association of Pharmaceutical Scientists 9th Annual Meeting San Diego,
`CA November, 1994. Pharm. Res. 11, S205, 1994.
`
`"Selecting Nonabsorbable Markers to Study Water Flux During In Situ Nasal Perfusions" Pei-Fen
`Chou and Maureen D. Donovan. American Association of Pharmaceutical Scientists 9th Annual
`Meeting San Diego, CA November, 1994. Pharm. Res. 11, S206, 1994.
`
`"In Vitro and In Vivo Correlations of Drug Permeability through the Nasal Mucosa" Benjamin P.
`Kuo, Hsiao-Hui Wu, and Maureen D. Donovan American Association of Pharmaceutical
`Scientists 9th Annual Meeting San Diego, CA November, 1994. Pharm. Res. 11, S206, 1994.
`
`“Rheological Characteristics and Intestinal Bioadhesion of Polymer Gels” Mengping Zhou, Diane
`Venice, Douglas R. Flanagan, and Maureen D. Donovan 22nd International Symposium on
`Controlled Release of Bioactive Materials. Seattle, WA July, 1995. Proc. Int. Symp. Control.
`Rel. Bioactiv. Mat. 22, 310-11, 1995.
`
`“Microsphere Transport Pathways in the Rabbit Nasal Mucosa” Ye Huang and Maureen D.
`Donovan 22nd International Symposium on Controlled Release of Bioactive Materials. Seattle,
`WA July, 1995. Proc. Int. Symp. Control. Rel. Bioactiv. Mat. 22, 622-3, 1995.
`
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`“Effects of Bioadhesive Polymer Gels on Nasal Mucociliary Clearance” Mengping Zhou and
`Maureen D. Donovan American Association of Pharmaceutical Scientists 10th Annual Meeting
`Miami, FL November, 1995. Pharm. Res. 12, S290, 1995.
`
`“Characterization of Lipid-DNA Complexes Formed between Lipofectin and Calf Thymus DNA”
`Alan M. Goldberg, Douglas R. Flanagan, and Maureen D. Donovan American Association of
`Pharmaceutical Scientists 10th Annual Meeting Miami, FL November, 1995. Pharm. Res. 12,
`S267, 1995.
`
`“Effect of Osmolarity on Plasma Secretion into the Nasal Cavity” Pei-Fen Chou and Maureen D.
`Donovan American Assocaition of Pharmaceutical Scientists 10th Annual Meeting Miami, FL
`November, 1995. Pharm. Res. 12, S316, 1995.
`
`“Drug Permeation through Cystic Fibrosis Mucus Solution” Pavan G. Bhat, Douglas R. Flanagan,
`and Maureen D. Donovan American Association of Pharmaceutical Scientists 10th Annual
`Meeting Miami, FL November, 1995. Pharm. Res. 12, S244, 1995.
`
`“Correlation between Drug Diffusion through Cystic Fibrotic Mucus and Rheological Properties
`and Glycoprotein Morphology” Pavan G. Bhat, Douglas R. Flanagan, and Maureen D. Donovan
`American Association of Pharmaceutical Scientists Annual Meeting Seattle, WA October, 1996.
`Pharm. Res. 13, S170, 1996.
`
`“Determination of Diffusion Coefficients of Sodium p-Aminosalicylate in Sheep Nasal Mucosae
`and Dialysis Membranes Using FT-IR-H-ATR Spectroscopy” Nahathai Nardviryakul, Dale Eric
`Wurster, and Maureen D. Donovan American Association of Pharmaceutical Scientists Annual
`Meeting Seattle, WA October, 1996. Pharm. Res. 13, S170, 1996.
`
`“Modification of the Sol-Gel Transition Temperature and Gelling Time of Pluronic F127 Using
`Ionic and Non-Ionic Additives” Ye Huang and Maureen D. Donovan American Association of
`Pharmaceutical Scientists Annual Meeting Seattle, WA October, 1996. Pharm. Res. 13, S212,
`1996.
`
`“Intranasal Delivery of Local Anesthetics into the Central Nervous System” Kang Jye Chou and
`Maureen D. Donovan American Association of Pharmaceutical Scientists Annual Meeting
`Seattle, WA October, 1996.
`
`“The Role of Water Flux in Altering Nasal Bioavailability” Pei-Fen Chou and Maureen D.
`Donovan American Association of Pharmaceutical Scientists Annual Meeting San Francisco, CA
`November, 1998. PharmSci 1, S388, 1998.
`
`“An In Vitro Testing System for Assessing Performance of Vaginal Suppositories” V. Mark
`Kothapali, Nahathai Nardviriyakul, Eric R. Butikofer, Michelle L. Maynard, Dale Eric Wurster, and
`Maureen D. Donovan American Association of Pharmaceutical Scientists Annual Meeting San
`Francisco, CA November, 1998. PharmSci 1, S494, 1998.
`
`“Effect of Processing Variables on Adenoviral Vector Infectivity” Jeffrey J. Scott and Maureen D.
`Donovan American Association of Pharmaceutical Scientists Annual Meeting Indianapolis, IN
`October, 2000. PharmSci 4, S2285, 2000.
`
`“Drug Permeation through Excised Bovine Olfactory Mucosa” Karunya Kandimalla and Maureen
`D. Donovan American Association of Pharmaceutical Scientists Annual Meeting Indianapolis, IN
`October, 2000. PharmSci 4, S3270, 2000.
`
`“Differential Transport Properties of Antihistamines across Olfactory and Respiratory Mucosae”
`Karunya Kandimalla and Maureen D. Donovan American Association of Pharmaceutical
`Scientists Annual Meeting Denver, CO October, 2001. AAPS PharmSci 3(3), 2001.
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`“Influence of Emitted Spray Angle on Nasal Deposition Efficiency” Mow Yee Foo and Maureen D.
`Donovan. American Association of Pharmaceutical Scientists Annual Meeting. Toronto, Canada
`November 11, 2002. AAPS PharmSci 4(4), M1326.
`
`“Dopamine Transport and Metabolism across the Nasal Mucosa” Nagendra Chemuturi and
`Maureen D. Donovan. American Association of Pharmaceutical Scientists Annual Meeting.
`Toronto, Canada November 14, 2002. AAPS PharmSci 4(4), R6127.
`
`“Carrier Mediated Transport of Small Molecules across Bovine Olfactory Mucosa: Implications In
`Nose To Brain Transport” Karunya Kandimalla and Maureen D. Donovan. American Association
`of Pharmaceutical Scientists Annual Meeting, Salt Lake City UT October, 2003. AAPS PharmSci
`5(4), T3140 (2003).
`
`“Characterization Of Viscoelastic Properties Of Formulations Resistant To Mucociliary Clearance”
`Ankur J. Shah and Maureen D. Donovan. American Association of Pharmaceutical Scientists
`Annual Meeting, Salt Lake City, UT AAPS PharmSci 5(4), R6144 (2003).
`
`“Drug Permeability Across Bovine Respiratory Tissues Compared To A Human Tracheobronchial
`Cell Culture (Epiairway™)” Nagendra Venkata Chemuturi, Maureen D Donovan, Patrick J
`Hayden, Mitchell Klausner AAPS Annual Meeting, Salt Lake City, UT October, 2003 AAPS
`PharmSci 5(4), T3102 (2003).
`
`“Dopamine Transport And Metabolism across Nasal Mucosa” Nagendra Chemuturi and Maureen
`D. Donovan. AAPS Annual Meeting, Salt Lake City UT October, 2003. AAPS PharmSci, 5(4),
`T3103 (2003).
`
`“Dopamine Transport across Respiratory Epithelium” Nagendra Venkata Chemuturi, Patrick J
`Hayden, Mitchell Klausner, Maureen D. Donovan AAPS Annual Meeting, Salt Lake City UT
`October, 2003. AAPS PharmSci 5(4), T3104 (2003).
`
`“Formulation of Adenoviral Vectors with Inhibitors of Mucociliary Clearance Enhances Gene
`Transfer to Airway Epithelia In Vivo” Patrick L. Sinn, Ankur Shah, Maureen D. Donovan, Paul B.
`McCray, Jr. American Society of Gene Therapy Annual Meeting, Minneapolis MN June, 2004.
`Mol Therapy, 9, Suppl. 1, S191, 2004.
`
`“Reducing mucociliary clearance rates through rheological property optimization” Ankur J Shah
`and Maureen D. Donovan. AAPS Annual Meeting, Baltimore MD November, 2004. AAPS J,
`6(Suppl), 2004.
`
`“Nose to brain dopamine delivery: Targeting dopamine transporter and organic cation transporter-
`2 for improved CNS bioavailability and therapeutic effect” Nagendra V. Chemuturi and Maureen
`D. Donovan. AAPS Annual Meeting, Baltimore MD November, 2004. AAPS J, 6(Suppl),W4290,
`2004.
`
`“Localization of p-glycoprotein in human tracheal/bronchial epithelial cell culture (EpiAirway)
`system” Nagendra V. Chemuturi NV and Maureen D. Donovan. AAPS Annual Meeting,
`Baltimore MD November, 2004. AAPS J, 6 (Suppl), W4289, 2004.
`
`“Influence of viscosity and surface tension on nasal spray characteristics” Mow Yee Foo and
`Maureen D. Donovan. AAPS Annual Meeting, Baltimore MD November, 2004. AAPS J,
`6 (Suppl), M1137, 2004.
`
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`“Nose to brain delivery – Characterization of biomolecular processes controlling dopamine
`transport across the nasal mucosa” Nagendra V. Chemuturi and Maureen D. Donovan. AAPS
`Annual Meeting, Nashville, TN. November, 2005.
`
`“Rheological characterization of bioadhesive polymer gels with reduced mucociliary transit rates”
`Ankur J. Shah and Maureen D. Donovan. AAPS Annual Meeting, Nashville, TN. November,
`2005.
`
`“Optimization of bioadhesive gels for extending intranasal residence time” Ankur J. Shah and
`Maureen D. Donovan. AAPS Annual Meeting, Nashville, TN. November, 2005.
`
`“Spray characteristics for optimal deposition beyond the nasal valve” Mow Yee Foo and Maureen
`D. Donovan AAPS Annual Meeting, Nashville, TN November, 2005.
`
`“Permeation and metabolism of cocaine in the nasal mucosa” Hefei Zhang and Maureen D.
`Donovan. AAPS Annual Meeting, San Antonio, TX, October, 2006.
`
`“Deposition of nasal sprays in an MRI-derived human nasal airway cast” Mow Yee Foo, YS
`Cheng, WC Su, and Maureen D. Donovan. AAPS Annual Meeting, San Antonio, TX, October,
`2006.
`
`“Nanoparticulate movement through viscoelastic barriers” Chen Ming Lee and Maureen D.
`Donovan. AAPS Annual Meeting, San Antonio, TX, October, 2006.
`
`“Permeation of L-Phenylalanine across the Nasal Mucosa” Hefei Zhang and Maureen D.
`Donovan. AAPS Annual Meeting, San Diego, CA. AAPS Journal, Vol. 9, No. S2, Abstract T2023
`(2007).
`
`“A Geometric Approach to Simulating Nasal Spray Deposition Efficiency” Mow Yee Foo, YS
`Cheng, WC Su, and Maureen D. Donovan. AAPS Annual Meeting, San Diego, CA, November,
`2007, AAPS Journal Vol. 9, No. S2, Abstract W5254 (2007).
`
`“Nanoparticulate Movement in Concentrated Polymer Solutions” Chen Ming Lee and Maureen D.
`Donovan. AAPS Annual Meeting, San Diego, CA. AAPS Journal, Vol 9, No. S2, Abstract W4198
`(2007).
`
`“Measurement of Drug Transport in the Mammary Epithelium Using Cytometric Methods”. Joanne
`E. Reiland and Maureen D. Donovan. AAPS Annual Meeting, San Diego, CA. AAPS Journal Vol.
`9, No. S2, Abstract T2021 (2007).
`
`“A Novel Biotinylated Chitosan Polymer for Applications in Tissue Engineering and Gene
`Delivery” Aiman Abbas, Maureen Donovan,Aliasger Salem. AAPS Annual Meeting, San Diego,
`CA. AAPS Journal, Vol 9, No. S2, Abstract T3044 (2007).
`
`“Analysis of Mitoxantrone Uptake and Efflux in Mammary Epithelial Cells Using Flow Cytometry”.
`JE Reiland and MD Donovan, AAPS Annual Meeting, Atlanta, GA, AAPS Journal 10(S2), 2524,
`(2008).
`
`“Development of a Predictive Relationship between Nasal Membrane Permeability and Nasal
`Absorption Rate Constant”. H Zhang and MD Donovan, AAPS Annual Meeting, Atlanta, GA.
`AAPS Journal 10(S2), 2916, (2008).
`
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`“Chitosan-Dextran Sulfate as Vaccine Delivery Systems “AO Abbas, MD Donovan, AK Salem.
`AAPS Annual Meeting, Los Angeles, CA. AAPS Journal 11(S2), 3849, 2009.
`www.aapsj.org/abstracts/AM