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Patent Owner

10x Genomics, Inc.

Petitioner

Parse Biosciences

Assignee

POPULATION GENETICS TECHNOLOGIES LTD.

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Parse Biosciences v. 10x Genomics, Inc.

IPR2023-00876 | Patent Trial and Appeal Board

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Filed April 20, 2023

Terminated Sept. 17, 2024

Judges Devon Zastrow Newman, Michael Fitzpatrick, Sheridan Snedden, and Kristi Sawert

Case Type Inter Partes Review

Status Final Written Decision - Appealed

Challenged Patent 15/677,957

Patent No. 10,155,981 assignments

Tech Center 1600

Art Unit 1639

Inventors Sydney Brenner, Gi Mikawa, Robert Osborne, Andrew Slatter

Last Updated: 11 minutes ago

Filing Date	#	Filing and Exhibits
Entries matching. Show All.
11/15/2024	11-15-2024-Patent_Owner	Event: Notice of Appeal Patent Owner Notice: notice of appeal 48: Patent Owner's Notice of Appeal
9/17/2024	09-17-2024-Board	Event: Final Written Decision (All Claims Cancelled) Board Final Written Decision: original 47: Final Written Decision: original
8/13/2024	08-13-2024-Board	Board Other: Hearing transcript 46: Other: Hearing transcript
7/23/2024	07-23-2024-Patent_Owner	Patent Owner Other: other 44: Patent Owner's Submission of Unresolved Objections to Petitioner's Demonstratives
7/23/2024	07-23-2024-Petitioner	Petitioner Other: other 45: Petitioner's Objections to Patent Owner's Demonstratives
7/19/2024	07-19-2024-Patent_Owner	Patent Owner Other: other 42: Patent Owner 10x Genomics, Inc.’s Demonstrative Slides
7/19/2024	07-19-2024-Petitioner	Petitioner Other: other 43: Petitioner Parse Biosciences, Inc.'s Oral Argument Demonstrative
7/5/2024	07-05-2024-Petitioner	Petitioner Reply to Opposition 41: Petitioner's Reply to Patent Owner's Opposition to Motion to Exclude
7/5/2024	07-05-2024-Patent_Owner	Patent Owner Other: other 40: Patent Owner's Reply in Support of its Motion to Exclude
7/2/2024	07-02-2024-Patent_Owner	Patent Owner Other: other 39: Patent Owner's Supplemental Paper Regarding Quakenbush Report Excerpt
6/28/2024	06-28-2024-Patent_Owner	Patent Owner Other: other 38: Patent Owner's Opposition to Petitioner's Motion to Exclude
6/28/2024	06-28-2024-Petitioner	Petitioner Opposition 37: Petitioner’s Opposition to Patent Owner’s Motion to Exclude Petitioner Exhibit 1068: EX1068
6/25/2024	06-25-2024-Petitioner	Petitioner Notice: Other 36: Petitioner's Supplemental Paper In Support Of Submission Of Dr. Quackenbush Report Excerpt Petitioner Exhibit 1067: EX1067
6/21/2024	06-21-2024-Patent_Owner	Patent Owner Motion: Other 35: Patent Owner's Motion to Exclude
6/21/2024	06-21-2024-Petitioner	Petitioner Motion: Other 34: Petitioner's Motion to Exclude
6/20/2024	06-20-2024-Board	Board Order: on Motion 33: ORDER Conduct of the Proceeding 37 C.F.R. § 42.5
5/31/2024	05-31-2024-Board	Board Order: Other 32: Setting Oral Argument 37 C.F.R. § 42.70
5/29/2024	05-29-2024-Patent_Owner	Patent Owner Other: other 31: Patent Owner's Request for Oral Hearing
5/23/2024	05-23-2024-Petitioner	Petitioner Other: other 30: Petitioner’s Supplemental Paper Regarding Why Petitioner’s Arguments Are Not New Or Improper
5/22/2024	05-22-2024-Petitioner	Petitioner Exhibit 1066: EX1066
5/17/2024	05-17-2024-Petitioner	Petitioner Other: other 27: Petitioner’s Objections To Evidence Under 37 C.F.R. § 42.64 Petitioner Other: other 28: Petitioner’s Request For Oral Argument Pursuant To 37 C.F.R. § 42.70(a)
5/17/2024	05-17-2024-Patent_Owner	Patent Owner Other: other 29: Patent Owner's Objections to Evidence
5/10/2024	05-10-2024-Patent_Owner	Patent Owner Other: other 25: Patent Owner’s Authorized Supplemental Paper Identifying Exemplary New and Improper Arguments and Theories in Petitioner’s Reply and Related Papers Patent Owner Other: other 26: Patent Owner's Sur-Reply Patent Owner Exhibit 2020: EX2020 - May 2, 2024 Deposition Transcript of Gregory Cooper, Ph.D. Patent Owner Exhibit 2021: EX2021 - Parse Biosciences, Inc. v. 10x, Genomics Inc., IPR2023-00955, Pap.1 (May 25, 2023) Patent Owner Exhibit 2022: EX2023 - Parse Biosciences, Inc. v. 10x Genomics, Inc. IPR2023-00955, EX1002 (Apr. 20, 2023) (Declaration of Gregory Cooper, Ph.D.) Patent Owner Exhibit 2101: EX2101 - S. Guan, A. Blanchard, P. Zhang, & Z. Zhu, Alteration of Sequence Specificity of the Type IIS Restriction Endonuclease BtsI, (July 26, 2010) (marked as EX2101 in Dr. Cooper’s May 2, 2024 deposition (EX2020)) Patent Owner Exhibit 2102: EX2102 - C. Wansgasnuwat et al, Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion, BMC Genomics (2020) 21:717 (marked as EX2102 in Dr. Cooper’s May 2, 2024 deposition (EX2020)) Patent Owner Exhibit 2103: EX2103 - V. Llorens-Rico et al, Single-cell approaches in human microbiome research, Cell (2022) 185:2725 (marked as EX2103 in Dr. Cooper’s May 2, 2024 deposition (EX2020)) Patent Owner Exhibit 2104: EX2104 - N. Sarkar, Polyadenylation of mRNA in Prokaryotes, Annu. Rev. Biochem (1997) 66:173-97 (marked as EX1067 in Dr. Cooper’s May 2, 2024 deposition (EX2020)) Patent Owner Exhibit 2105: EX2105 - S. Slomovic et al., RNA Polyadenylation in Prokaryotes and Organelles; Different Tails Tell Different Tales, Critical Revs. In Plant Scis. (2006) 25:65-77 (marked as EX1068 in Dr. Cooper’s May 2, 2024 deposition (EX2020))
4/18/2024	04-18-2024-Patent_Owner	Patent Owner Notice: Notice of deposition 24: Deposition Notice of Gregory Cooper, Ph.D.
4/5/2024	04-05-2024-Patent_Owner	Patent Owner Other: other 23: Patent Owner's Objections to Evidence
3/29/2024	03-29-2024-Petitioner	Petitioner Pet Reply to PO Resp 22: Petitioner's Reply to Patent Owner's Response Petitioner Exhibit 1057: EX1057 Petitioner Exhibit 1058: EX1058 Petitioner Exhibit 1059: EX1059 Petitioner Exhibit 1060: EX1060 Petitioner Exhibit 1061: EX1061 Petitioner Exhibit 1062: EX1062 Petitioner Exhibit 1063: EX1063 Petitioner Exhibit 1064: EX1064 Petitioner Exhibit 1065: EX1065
2/23/2024	02-23-2024-Board	Board Order: on Motion 21: ORDER Granting Petitioner’s Motions for Pro Hac Vice Admission of Edward R. Reines 37 C.F.R. § 42.10
2/20/2024	02-20-2024-Petitioner	Petitioner Notice: Notice of deposition 20: PETITIONER PARSE BIOSCIENCES, INC.’S NOTICE OF DEPOSITION OF JOHN QUUACKENBUSH
2/16/2024	02-16-2024-Petitioner	Petitioner Notice: Updated Mandatory Notice 16: Petitioner Parse Biosciences, Inc.'s Supplemental Mandatory Notice Adding Backup Counsel Under 37 C.F.R. Section 42.8(a)(3) Petitioner Notice: Power of Attorney 17: Petitioner Parse Biosciences, Inc.'s Supplemental Power of Attorney for Edward R. Reines Petitioner Motion: PHV 18: Petitioner Parse Biosciences, Inc.'s Motion for Admission Pro Hac Vice of Edward R. Reines Pursuant to 37 C.F.R. Section 42.10 Petitioner Notice: Exhibit list 19: Petitioner Parse Biosciences, Inc.'s Updated Exhibit List Petitioner Exhibit 1054: Exhibit 1054 - Declaration of Edward R. Reines in support of pro hac vice motion Petitioner Exhibit 1055: Exhibit 1055 - In re Reines Federal Circuit decision, 14-MA0004 Petitioner Exhibit 1056: Exhibit 1056 - Personal Statement of Edward R. Reines, Fed. Cir. 14-MA004
1/16/2024	01-16-2024-Board	Board Order: Other 14: EXPUNGED Board Order: Other 15: Panel Change Order
1/12/2024	01-12-2024-Patent_Owner	Patent Owner Exhibit 2013: EX2013 - Declaration of John Quackenbush, Ph.D. (Corrected)
1/5/2024	01-05-2024-Patent_Owner	Patent Owner PO Response to Pet 13: Patent Owner's Response Patent Owner Exhibit 2011: EX2011 - Parse Biosciences, Inc. v. 10x, Genomics Inc., IPR2023-00958, EX1002 (May 25, 2023) (Declaration of Gregory Cooper, Ph.D) Patent Owner Exhibit 2012: EX2012 - Parse Biosciences, Inc. v. 10x, Genomics Inc., IPR2023-00958, EX1054 (May 25, 2023) (Georgi K. Marinov et al., From single-cell to cell-pool transcriptomes: Stochasticaly in gene expression and RNA splicing, 24.3 Genome Research 496-510 (2014) (“Marinov”)) Patent Owner Exhibit 2013: EXPUNGED Patent Owner Exhibit 2014: EX2014 - Bruce Alberts, et al., Molecular Biology of the Cell, Garland Science (4th ed. 2002) Patent Owner Exhibit 2015: EX2015 - Declaration of Sayem Osman Patent Owner Exhibit 2016: EX2016 - Piovesan et al., On the length, weight, and GT content of the human genome, BMC Res. Notes 12:106 (2019) (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391780/#:~:text=Considering%20a%20mean%20weight%20in,units%2Fcarat.htm) Patent Owner Exhibit 2017: EX2017 - T. Chauhan, T4 DNA Ligase: Introduction, Functions, Applications, and Protocol, (available at https://geneticeducation.co.in/t4-dna-ligase/) Patent Owner Exhibit 2018: EX2018 - Deposition Transcript of Gregory Cooper, Ph.D. Patent Owner Exhibit 2019: EX2019 - Li et al., Amplification and analysis of DNA sequences in single human sperm and diploid cells, Nature 335(6189):414-417 (1998)
12/4/2023	12-04-2023-Patent_Owner	Patent Owner Notice: Notice of deposition 12: Notice of Deposition of Gregory Cooper, Ph.D.
10/27/2023	10-27-2023-Patent_Owner	Patent Owner Other: other 11: Patent Owner's Objections to Evidence
10/24/2023	10-24-2023-Board	Board Notice: Other 9: EXPUNGED Board Notice: Other 10: ERRATA
10/13/2023	10-13-2023-Board	Event: Petition Institution (Granted) Board Institution Decision: Grant 7: Institution Decision: Grant Board Order: Other 8: Order: Scheduling Order
7/28/2023	07-28-2023-Patent_Owner	Event: Preliminary Response Patent Owner POPR: filed 6: Patent Owner's Preliminary Response Patent Owner Exhibit 2001: EX2001 - U.S. Patent Pub. No. 2007/0020640 A1 Patent Owner Exhibit 2002: EX2002 - File History of U.S. App. No. 13/859,450 Patent Owner Exhibit 2003: EX2003 - Dictionary of Microbiology and Molecular Biology (2d ed. 1987) Patent Owner Exhibit 2004: EX2004 - File History of U.S. App. No. 14/792,094 Patent Owner Exhibit 2005: EX2005 - File History of U.S. App. No. 13/387,343 Patent Owner Exhibit 2006: EX2006 - U.S. Patent Pub. No. 2007/0238113 Patent Owner Exhibit 2007: EX2007 - Laird et al., Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules, 101 PNAS 204-09 (Dec. 12, 2003) Patent Owner Exhibit 2008: EX2008 - Parse Biosciences, Inc. v. 10x, Genomics Inc., IPR2023-00958, Pap.1, (May 25, 2023) Patent Owner Exhibit 2009: EX2009 - File History of U.S. App. No. 14/172,694 Patent Owner Exhibit 2010: EX2010 - Declaration of Sayem Osman
5/11/2023	05-11-2023-Patent_Owner	Patent Owner Notice: Mandatory Notice 4: Patent Owner's Mandatory Notices Patent Owner Notice: Power of Attorney 5: Patent Owner's Power of Attorney and Designation of Lead & Back-up Counsel
4/28/2023	04-28-2023-Board	Board Notice: Notice filing date accorded 3: Notice: Notice filing date accorded
4/20/2023	04-20-2023-Petitioner	Petitioner Petition: as filed 1: Petition : as filed Petitioner Notice: Power of Attorney 2: Notice : Parse Biosciences, Inc.'s Power of Attorney Petitioner Exhibit 1001: U.S. Patent No. 10,155,981 Petitioner Exhibit 1002: Declaration of Gregory Cooper, Ph.D. Petitioner Exhibit 1003: PCT Patent Publication No. WO 2010/117620 (Linnarsson) Petitioner Exhibit 1004: Encoding PCR Products with Batch-Stamps and Barcodes (McCloskey) Petitioner Exhibit 1005: U.S. Patent No. 10,155,981 FH Petitioner Exhibit 1006: Gene expression in individual cells (Brail) Petitioner Exhibit 1007: Measurement of Number of Molecules (Hug) Petitioner Exhibit 1008: Twenty-five years of quantitative PCR (VanGuilder) Petitioner Exhibit 1009: Polymerase Chain Reaction (Schochetman) Petitioner Exhibit 1010: PCR-Induced Sequence Artifacts and Bias (Acinas) Petitioner Exhibit 1011: A genome-wide study of preferential (Yang) Petitioner Exhibit 1012: Amplification biases: possible difference (Degrelle) Petitioner Exhibit 1013: Molecular barcodes detect redundancy (Miner) Petitioner Exhibit 1014: U.S. Patent No. 8,298,767 Petitioner Exhibit 1015: U.S. Patent Provisional Application No. 61/164,759 (Linnarsson Provisional) Petitioner Exhibit 1016: 10X Genomic’s Opening Br ISO Mtn to Dismiss Petitioner Exhibit 1017: 10X Genomic’s Reply Br ISO Mtn to Dismiss Petitioner Exhibit 1018: Scheduling Order Petitioner Exhibit 1019: Federal Judicial Caseload Statistics (2022) Petitioner Exhibit 1020: Gregory Cooper CV Petitioner Exhibit 1021: The Use of Coded PCR Primers (Binladen) Petitioner Exhibit 1022: Effects of primer-template mismatches (Kwok) Petitioner Exhibit 1023: Motion Success for Stay Pending IPR In Delaware District Petitioner Exhibit 1024: High-Efficiency Cloning of Full-Length (Okayma) Petitioner Exhibit 1025: Chapter 6 How Cells read the Genome Petitioner Exhibit 1026: Assignment Record for U.S. Patent 8,298,767 Petitioner Exhibit 1027: 10x Genomics Legal Notice Petitioner Exhibit 1028: Declaration of Sylvia D. Hall-Ellis, Ph.D. Petitioner Exhibit 1029: US Patent No. 8,835,358 Petitioner Exhibit 1030: Translation: DNA to mRNA to Protein (Clancy) Petitioner Exhibit 1031: Defining cell types and states (Trapnell) Petitioner Exhibit 1032: Representative in Vitro cDNA Amplification (Brady) Petitioner Exhibit 1033: Analysis of gene expression (Eberwine) Petitioner Exhibit 1034: Normalization and Subtraction (Bonaldo) Petitioner Exhibit 1035: In vitro cloning of complex mixtures (Brenner) Petitioner Exhibit 1036: Polymerase Chain Reaction (Persing) Petitioner Exhibit 1037: An improved single-cell cDNA amplification (Kurimoto) Petitioner Exhibit 1038: Method for single-cell microarray analysis (Esumi) Petitioner Exhibit 1039: Cloning Full-length, Cap-Trapper-Selected (Shibata) Petitioner Exhibit 1040: U.S. Patent Application 2004/0166499 Petitioner Exhibit 1041: An Overview of Next-Generation Sequencing (Gkazi) Petitioner Exhibit 1042: Relocalization of elF4E by its binding partners Petitioner Exhibit 1043: DNA sequencing: bench to bedside and beyond Petitioner Exhibit 1044: Keeping Uracil Out of DNA (Vertessy) Petitioner Exhibit 1045: Next-Generation DNA Sequencing Methods (Mardis) Petitioner Exhibit 1046: Next-Generation DNA Sequencing (Shendure) Petitioner Exhibit 1047: The impact of next-generation sequencing (Mardis 2) Petitioner Exhibit 1048: The new paradigm of flow cell (Holt) Petitioner Exhibit 1049: National Human Genome Research Institute, Nucleotide Petitioner Exhibit 1050: National Human Genome Research Institute, Polymerase Chain Petitioner Exhibit 1051: Becton, Dickinson and Company and Cellular Research, Inc.’s First Amended Petitioner Exhibit 1052: Exhibits 26 and 27 Petitioner Exhibit 1053: US 9,708,659

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Parse Biosciences v. 10x Genomics, Inc.

IPR2023-00876 | Patent Trial and Appeal Board

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