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`17/548,379
`
`Examiner
`
`KAIJIANG ZHANG
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`05/21/2022
`
`KZ
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`U.S. Patent and Trademark Office
`
`Page 1 of 1
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`Part of Paper No.: 20220521
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`Personalis EX2024
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`
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`Ref
`#
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`L1
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`Hits
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`45
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`L2
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`25
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`L3
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`1,174
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`L4
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`44
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`LS
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`53
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`L6
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`97
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`L7
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`343
`
`EAST Search History (Prior Art)
`
`Search Query DBs
`
`Defa
`ult
`Oper
`ator
`(Gabor near2 Bartha).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`(Gemma near2 Chandratillake).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
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`(Richard near2 Chen).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`(Sarah near2 Garcia).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`(Hugo near3 Lam).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`(Shujun near2 Luo).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`(Mark near2 Pratt).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`Plurals
`
`Time Stamp
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`5/21/2022 8:56:46 PM
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`Page 1
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`Personalis EX2024
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`
`
`LS
`
`1,937
`
`L9
`
`3,507
`
`Ll0
`
`38
`
`Lll
`
`38
`
`L12
`
`38
`
`L13
`
`15
`
`L14
`
`53
`
`EAST Search History (Prior Art)
`
`(John near2 West).in. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L1 L2 L3 L 4 LS L6 L7 LS US-PG PUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L9 and ((enrich$5 captur$5 pull-down US-PGPUB; OR
`pulldown) with probe with (polymorphism USPAT;
`SNP inDel SNV mutation insertion deletion
`USOCR;
`variant variation)) FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`Ll0 and (WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`Lll and ((cancer carcinoma tumor) same US-PGPUB; OR
`(mutation polymorphism SNP indel variant USPAT;
`viriation insertion deletion)) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L9 and ((WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`same ((enrich$5 captur$5 pull-down
`USOCR;
`pulldown) with (polymorphism SNP inDel
`FPRS;
`SNV mutation insertion deletion variant
`EPO; JPO;
`variation))) DERWENT;
`IBM_TDB
`
`Personal is.as. US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`ON
`
`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:37
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`ON
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`2022/05/21 20:41
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`ON
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`2022/05/21 20:42
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`5/21/2022 8:56:46 PM
`C: \Users\kzha ng\Docu ments\EAST\ Workspaces\17548379. wsp
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`Page 2
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`Personalis EX2024
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`
`
`L15
`
`19
`
`L16
`
`17
`
`L17
`
`17
`
`L18
`
`7
`
`L19
`
`544
`
`L20
`
`411
`
`L21
`
`46
`
`EAST Search History (Prior Art)
`
`L14 and ((enrich$5 captur$5 pull-down US-PGPUB; OR
`pulldown) with probe with (polymorphism USPAT;
`SNP inDel SNV mutation insertion deletion
`USOCR;
`variant variation)) FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L15 and (WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L16 and ((cancer carcinoma tumor) same US-PGPUB; OR
`(mutation polymorphism SNP indel variant USPAT;
`viriation insertion deletion)) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L14 and ((WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`same ((enrich$5 captur$5 pull-down
`USOCR;
`pulldown) with (polymorphism SNP inDel
`FPRS;
`SNV mutation insertion deletion variant
`EPO; JPO;
`variation))) DERWENT;
`IBM_TDB
`
`(WGS ("whole genome" near3 sequenc$3) US-PGPUB; OR
`(genom$3 adj sequencing)) same ((enrich$5 USPAT;
`captur$5 pull-down pulldown) with
`USOCR;
`(polymorphism SNP inDel SNV mutation
`FPRS;
`insertion deletion variant variation)) EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L19 and ((cancer carcinoma tumor) same US-PGPUB; OR
`(mutation polymorphism SNP indel variant USPAT;
`viriation insertion deletion)) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L20 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`ON
`
`2022/05/21 20:42
`
`ON
`
`2022/05/21 20:42
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`ON
`
`2022/05/21 20:42
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`ON
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`2022/05/21 20:42
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`ON
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`2022/05/21 20:43
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`ON
`
`2022/05/21 20:43
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`ON
`
`2022/05/21 20:43
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`5/21/2022 8:56:46 PM
`C: \Users\kzha ng\Docu ments\EAST\ Workspaces\17548379. wsp
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`Page 3
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`Personalis EX2024
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`
`
`L22
`
`76
`
`L23
`
`5
`
`L24
`
`420
`
`L25
`
`142
`
`L26
`
`7
`
`L27
`
`4,395
`
`L28
`
`1,391
`
`EAST Search History (Prior Art)
`
`(WGS ("whole genome" near3 sequenc$3) US-PGPUB; OR
`(genom$3 adj sequencing)) same ((enrich$5 USPAT;
`captur$5 pull-down pulldown) with probe USOCR;
`with (polymorphism SNP inDel SNV mutation FPRS;
`insertion deletion variant variation)) EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L22 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`((enrich$5 captur$5 pull-down pulldown) US-PGPUB; OR
`with probe with (polymorphism SNP inDel USPAT;
`SNV mutation insertion deletion variant USOCR;
`variation)) same (cancer carcinoma tumor) FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L24 and (WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L25 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`((enrich$5 captur$5 pull-down pulldown) US-PGPUB; OR
`with (polymorphism SNP inDel SNV mutation USPAT;
`insertion deletion variant variation)) same
`USOCR;
`(cancer carcinoma tumor) FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L27 and (WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`ON
`
`2022/05/21 20:43
`
`ON
`
`2022/05/21 20:43
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`ON
`
`2022/05/21 20:44
`
`ON
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`2022/05/21 20:44
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`ON
`
`2022/05/21 20:44
`
`ON
`
`2022/05/21 20:45
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`ON
`
`2022/05/21 20:45
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`5/21/2022 8:56:46 PM
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`Page 4
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`Personalis EX2024
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`
`
`L29
`
`150
`
`L30
`
`3
`
`L31
`
`485
`
`L32
`
`270
`
`L33
`
`232
`
`L34
`
`13
`
`L35
`
`17
`
`EAST Search History (Prior Art)
`
`L28 and ((polymorphism SNP inDel SNV US-PGPUB; OR
`mutation insertion deletion variant variation) USPAT;
`same (TruSeq SureSelect SeqCap)) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L29 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`(polymorphism SNP inDel SNV mutation US-PGPUB; OR
`insertion deletion variant variation) same USPAT;
`((enrich$5 captur$5 pull-down pulldown) USOCR;
`with (TruSeq SureSelect SeqCap)) FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L31 and (WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L32 and ((cancer carcinoma tumor) same US-PGPUB; OR
`(mutation polymorphism SNP indel variant USPAT;
`viriation insertion deletion)) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L33 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L32 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`ON
`
`2022/05/21 20:45
`
`ON
`
`2022/05/21 20:45
`
`ON
`
`2022/05/21 20:45
`
`ON
`
`2022/05/21 20:45
`
`ON
`
`2022/05/21 20:45
`
`ON
`
`2022/05/21 20:45
`
`ON
`
`2022/05/21 20:46
`
`5/21/2022 8:56:46 PM
`C: \Users\kzha ng\Docu ments\EAST\ Workspaces\17548379. wsp
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`Page 5
`
`Personalis EX2024
`
`
`
`L36
`
`420
`
`L37
`
`142
`
`L38
`
`7
`
`L39
`
`94
`
`L40
`
`12
`
`L41
`
`256
`
`L42
`
`20
`
`EAST Search History (Prior Art)
`
`((enrich$5 captur$5 pull-down pulldown) US-PGPUB; OR
`with probe with (polymorphism SNP inDel USPAT;
`SNV mutation insertion deletion variant USOCR;
`variation)) same (cancer $carcinoma tumor) FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L36 and (WGS ("whole genome" near3 US-PGPUB; OR
`sequenc$3) (genom$3 adj sequencing)) USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L37 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L19 and ((sample nucleic polynucleotide US-PGPUB; OR
`DNA) with ("time point" "later time" "earlier USPAT;
`time")) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L39 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L28 and ((sample nucleic polynucleotide US-PGPUB; OR
`DNA) with ("time point" "later time" "earlier USPAT;
`time")) USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L41 and (@pd<"20130117" US-PGPUB; OR
`@ad<"20130117") USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`ON
`
`2022/05/21 20:46
`
`ON
`
`2022/05/21 20:46
`
`ON
`
`2022/05/21 20:46
`
`ON
`
`2022/05/21 20:48
`
`ON
`
`2022/05/21 20:49
`
`ON
`
`2022/05/21 20:50
`
`ON
`
`2022/05/21 20:50
`
`5/21/2022 8:56:46 PM
`C: \Users\kzha ng\Docu ments\EAST\ Workspaces\17548379. wsp
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`Page 6
`
`Personalis EX2024
`
`
`
`L43
`
`16
`
`L44
`
`1
`
`L45
`
`1
`
`L46
`
`8
`
`L47
`
`1
`
`L48
`
`8
`
`EAST Search History (Prior Art)
`
`("10266890" I "10415091" I "11155867" I "2002 US-PGPUB; OR
`0006615" 1 "20050042668" 1 "20060184489" I" USPAT
`20060278241" I "20100042438" I "201100092
`96" I "20120077682" I "20120270206" I "20180
`051338" I "20210062258" I "20210238677" I "9
`128861"1"9745626").PN.
`L19 and L43 US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L24 and L43 US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L28 and L43 US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L39 and L43 US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`L41 and L43 US-PGPUB; OR
`USPAT;
`USOCR;
`FPRS;
`EPO; JPO;
`DERWENT;
`IBM_TDB
`
`ON
`
`2022/05/21 20:51
`
`ON
`
`2022/05/21 20:51
`
`ON
`
`2022/05/21 20:51
`
`ON
`
`2022/05/21 20:51
`
`ON
`
`2022/05/21 20:52
`
`ON
`
`2022/05/21 20:52
`
`EAST Search History (Interference)
`
`Ref
`#
`
`L49
`
`Hits
`
`44
`
`Search Query DBs
`
`Defa
`ult
`Oper
`ator
`(WGS ("whole genome" near3 sequenc$3) US-PGPUB; OR
`USPAT
`(genom$3 adj sequencing)).clm. and
`((enrich$5 captur$5 pull-down pulldown)
`with (polymorphism SNP inDel SNV mutation
`insertion deletion variant variation)).clm.
`
`5/21/2022 8:56:46 PM
`C: \Users\kzha ng\Docu ments\EAST\ Workspaces\17548379. wsp
`
`Plurals
`
`Time Stamp
`
`ON
`
`2022/05/21 20:53
`
`Page 7
`
`Personalis EX2024
`
`
`
`EAST Search History (Interference)
`
`LS0
`
`6
`
`L49 and ((sample nucleic polynucleotide US-PGPUB; OR
`DNA) with ("time point" "later time" "earlier USPAT
`time")).clm.
`
`ON
`
`2022/05/21 20:54
`
`5/21/2022 8:56:46 PM
`C: \Users\kzha ng\Docu ments\EAST\ Workspaces\17548379. wsp
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`Page 8
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`Personalis EX2024
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`