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`updated: May 12, 2023
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`Definition
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`An exome is the sequenceofall the exons ina
`genome,reflecting the protein-coding portion of a
`genome.In humans, the exome is about 1.5% of
`the genome.
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`Narration
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`Proteins are encoded by genes. And genesconsist
`of two major components, exonsand introns.
`Exons contain the nucleotides that directly encode
`for proteins, whereasintrons are stretches of DNA
`between the exons and do not encode for proteins.
`The entire collection of all the exons from all the
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`genes in a genomeis called an exome.In the case
`the human genome,the exome only corresponds to
`about 1.5% of the genome’s roughly 3 billion
`nucleotides. Genome scientists have developed
`laboratory methods that allow them to just
`sequence a genome’s exome;in other words,just
`the part of the genome that directly encodes for
`proteins. So, you will often hear genomicists talk
`about an exome sequence,whichis a very small
`part of the overall genome (or whole-genome)
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`sequence.
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`Glossary
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`Contig
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`Exon
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`PUTEDJ
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`Deoxyribonucleic
`Acid (DNA)
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