( 12 ) United States Patent
`Barnes
`
`( 10 ) Patent No .: US 11,179,144 B2
`( 45 ) Date of Patent :
`Nov. 23 , 2021
`
`US011179144B2
`
`( 54 ) MINIMALLY INVASIVE SURGICAL
`SYSTEM , APPARATUS AND METHOD
`( 71 ) Applicant : LIFE SPINE , INC . , Huntley , ?L ( US )
`( 72 ) Inventor : Bryan Barnes , Athens , GA ( US )
`( 73 ) Assignee : LIFE SPINE , INC . , Huntley , IL ( US )
`Subject to any disclaimer , the term of this
`( * ) Notice :
`patent is extended or adjusted under 35
`U.S.C. 154 ( b ) by 185 days .
`16 / 329,189
`Aug. 29 , 2017
`PCT / US2017 / 049135
`
`( 65 )
`
`( 21 ) Appl . No .:
`( 22 ) PCT Filed :
`( 86 ) PCT No .:
`$ 371 ( c ) ( 1 ) ,
`( 2 ) Date :
`Feb. 27 , 2019
`( 87 ) PCT Pub . No .: WO2018 / 044901
`PCT Pub . Date : Mar. 8 , 2018
`Prior Publication Data
`US 2019/0183473 A1
`Jun . 20 , 2019
`Related U.S. Application Data
`( 60 ) Provisional application No. 62 / 380,671 , filed on Aug.
`29 , 2016 .
`( 51 ) Int . Cl .
`A61B 17/17
`A61B 17/00
`
`( 2006.01 )
`( 2006.01 )
`( Continued )
`( 52 ) U.S. CI .
`CPC ... A61B 17/00234 ( 2013.01 ) ; A61B 17/1757
`( 2013.01 ) ; A61B 17/3423 ( 2013.01 ) ;
`( Continued )
`
`( 58 ) Field of Classification Search
`A61B 17/1757 , A61B 17/1739 ; A61B
`CPC
`2017/3455 ; A61B 2017/347 ;
`( Continued )
`References Cited
`U.S. PATENT DOCUMENTS
`
`( 56 )
`
`6,793,656 B1 *
`7,175,631 B2 *
`
`9/2004 Mathews
`
`2/2007 Wilson
`
`A61B 17/70
`623 / 17.16
`A61B 17/1703
`606/97
`
`( Continued )
`FOREIGN PATENT DOCUMENTS
`
`CN
`
`1909845 A
`
`2/2007
`
`OTHER PUBLICATIONS
`International Search Report and Written Opinion for International
`Application No. PCT / US2017 / 049135 , dated Nov. 2 , 2017 , 8 pages .
`( Continued )
`Primary Examiner Anu Ramana
`( 74 ) Attorney , Agent , or Firm — Foley & Lardner LLP
`( 57 )
`ABSTRACT
`Provided are systems , apparatuses , and methods for per
`forming minimally invasive spinal surgery . For example ,
`provided is a minimally invasive surgical apparatus for
`securing a pedicle screw or lateral mass screw to a vertebral
`lateral mass or pedicle . The example apparatus includes an
`instrument portal , a pedicle screw or lateral mass screw
`reducer , an anchor pin receiving chamber , an anchor pin , and
`a handle .
`
`16 Claims , 6 Drawing Sheets
`
`205
`
`220
`
`320
`
`210
`
`310
`325 0
`
`-100
`-200
`215
`
`ti
`230
`
`300
`
`255
`
`240
`
`260 245
`235
`
`225
`
`-250
`
`-265
`
`Globus Medical, Inc. Exhibit 2007, Page 1 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,179,144 B2
`Page 2
`
`( 51 ) Int . Ci .
`A61B 17770
`A61B 17/80
`A61B 1734
`A61B 17/90
`A61B 90/00
`( 52 ) U.S. Ci .
`CPC
`
`( 2006.01 )
`( 2006.01 )
`( 2006.01 )
`( 2006.01 )
`( 2016.01 )
`A61B 17/70 ( 2013.01 ) ; A61B 17/708
`( 2013.01 ) ; A61B 17/7074 ( 2013.01 ) ; A61B
`17/7082 ( 2013.01 ) ; A61B 17/80 ( 2013.01 ) ;
`A61B 2017/0042 ( 2013.01 ) ; A61B 2017/0092
`( 2013.01 ) ; A61B 2017/90 ( 2013.01 ) ; A61B
`2090/3966 ( 2016.02 )
`( 58 ) Field of Classification Search
`A61B 2017/3488 ; A61B 17/7074 ; A61B
`CPC
`17/7076 ; A61B 17/7079 ; A61B 17/708
`See application file for complete search history .
`References Cited
`
`( 56 )
`
`9,204,906 B2
`9,795,771 B2 *
`2004/0143265 Al *
`
`2006/0189997 A1
`2007/0142855 A1 *
`
`2010/0185245 A1 *
`
`12/2015 Cannestra
`10/2017 Trieu
`7/2004 Landry
`8/2006 Guenther et al .
`6/2007 Koysh
`7/2010 Paul
`
`2010/0262200 A1 10/2010 Ray et al .
`2012/0022597 A1
`1/2012 Gephart et al .
`2012/0253316 A1 * 10/2012 Oktavec
`
`2012/0277864 A1
`2013/0103036 Al
`2015/0327874 A1
`2016/0038195 Al
`2016/0143742 A1
`2016/0220278 A1
`
`11/2012 Brodke et al .
`4/2013 Mcghie
`11/2015 McBride
`2/2016 Genovese et al .
`5/2016 Asfora
`8/2016 Yue
`
`A61M 29/02
`A61B 17/7083
`606/86 A
`
`A61B 17/02
`606/191
`A61B 17/863
`606/304
`
`A61B 17/1757
`604/506
`
`OTHER PUBLICATIONS
`EPO Search Report for Application No. EP 17847374.0 dated Jul .
`10 , 2020 , 10 pages .
`First Office Action in CN 201780064751.1 dated Sep. 15 , 2021 ( no
`English translation available ) .
`* cited by examiner
`
`U.S. PATENT DOCUMENTS
`7,357,804 B2
`8,540,719 B2 *
`8,641,717 B2 *
`
`4/2008 Binder et al .
`9/2013 Peukert
`
`2/2014 Defossez
`
`A61B 17/708
`606/86 A
`A61B 17/8872
`606/86 R
`
`Globus Medical, Inc. Exhibit 2007, Page 2 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Nov. 23 , 2021
`
`Sheet 1 of 6
`
`US 11,179,144 B2
`
`210
`
`-205
`
`-100
`
`-220
`
`230
`225
`255 260
`240
`
`250
`
`265
`
`235
`
`245
`
`310
`325 0 D D
`-320
`
`FIG . 1
`
`200
`
`215
`
`227
`
`300
`
`315
`
`Globus Medical, Inc. Exhibit 2007, Page 3 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Nov. 23 , 2021
`
`Sheet 2 of 6
`
`US 11,179,144 B2
`
`205
`210
`
`-220
`
`-100
`-200
`215
`
`230
`
`320
`
`310
`3250 )
`
`300
`
`255
`
`240
`
`250
`
`-265
`
`260 245
`235
`
`225
`FIG . 2
`
`310
`
`-210 205
`
`-220
`
`325
`
`225
`300
`240
`
`200 100
`215 ) 315
`230
`
`250
`
`235 260
`
`-265
`
`255
`
`245
`FIG . 3
`
`225 210 205
`230
`?
`
`410
`
`255
`
`240
`
`-100
`
`-220
`
`-200
`215
`
`260
`235
`
`245
`
`FIG . 4
`
`405
`
`-400
`
`415
`
`250
`
`265
`
`Globus Medical, Inc. Exhibit 2007, Page 4 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Nov. 23 , 2021
`
`Sheet 3 of 6
`
`US 11,179,144 B2
`
`225
`
`210
`-200
`205 2207
`.
`215
`
`230
`.
`410 255 240 250 235 260 245
`
`-265
`
`-100
`
`-400
`
`-415
`-405
`
`520
`
`500
`
`515
`
`FIG . 5
`
`-510
`
`500
`510
`520
`
`205 ? 220
`11,210
`
`200
`215
`
`515
`
`410
`255
`
`240
`
`250 1.260
`245
`235
`265
`
`100
`
`225
`
`230
`?
`-400
`-415
`405
`FIG . 6
`
`500
`520 / 210 205
`
`220
`
`200
`215
`
`-100
`
`515
`
`410 255 240
`
`ol
`
`260 245
`250
`235
`265
`
`230
`415 -400
`FIG . 7
`
`405
`
`Globus Medical, Inc. Exhibit 2007, Page 5 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Nov. 23 , 2021
`
`Sheet 4 of 6
`
`US 11,179,144 B2
`
`500
`520
`
`205
`210
`
`220
`
`100
`200
`215 600 605
`
`515
`
`410
`255 240
`
`?
`250 4260 245 405
`415
`-235
`400
`265
`FIG . 8
`
`210
`
`225
`
`205
`
`220
`
`200
`215
`
`230
`1
`410
`255 240
`265
`
`1260 245
`250 235
`W
`720
`
`100
`
`405 -400
`
`-415
`
`715
`
`710
`700
`FIG . 9
`
`700
`
`710 210
`
`205
`
`220
`
`-200
`215
`
`225
`
`100
`
`230
`
`715 720
`?
`410
`
`255
`
`2504
`260
`235
`265
`
`240
`
`245
`
`415
`405 400
`FIG . 10
`
`Globus Medical, Inc. Exhibit 2007, Page 6 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Nov. 23 , 2021
`
`Sheet 5 of 6
`
`US 11,179,144 B2
`
`700
`
`715
`
`720
`
`210 205
`
`220
`
`200
`215
`
`410
`255 240
`
`250
`
`260 245
`235
`
`405
`
`265
`
`-100
`
`230
`415
`400
`
`FIG . 11
`
`700 205 )
`715 720 210
`800
`
`220
`
`-200
`710 215
`
`100
`FIG . 12
`
`715 720
`
`700
`210
`
`205
`
`-200
`
`220
`
`100
`
`-710 215
`Son
`
`410 255 240
`
`-250
`
`235 260
`
`245
`
`405
`
`415
`400
`
`-800
`FIG . 13
`-900
`
`Globus Medical, Inc. Exhibit 2007, Page 7 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Nov. 23 , 2021
`
`Sheet 6 of 6
`
`US 11,179,144 B2
`
`200
`
`205
`
`-215
`
`-800
`
`400
`
`FIG . 14
`
`235 250 245
`
`260
`255
`405 415
`
`900
`
`220
`
`200
`215
`
`205
`
`-210
`
`100
`.
`800
`
`-900
`
`410
`
`255
`
`240
`
`245
`
`250
`
`265
`
`260
`235
`FIG . 15
`
`415
`
`405
`400
`
`200
`
`205
`
`215
`
`800
`Junt
`
`250
`
`235
`
`260
`245 255
`
`415
`405
`FIG . 16
`
`-900
`
`Globus Medical, Inc. Exhibit 2007, Page 8 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`1
`MINIMALLY INVASIVE SURGICAL
`SYSTEM , APPARATUS AND METHOD
`
`US 11,179,144 B2
`
`2
`SUMMARY
`
`10
`
`2
`
`TECHNICAL FIELD
`
`Provided are systems , apparatuses , and methods for secur
`ing a pedicle screw or lateral mass screw to a vertebral
`5 lateral mass or pedicle during minimally invasive spinal
`This disclosure relates to minimally invasive spinal sur-
`surgery .
`gery , and more particularly to devices for securing a pedicle
`In an embodiment , an example system includes a mini
`e
`screw or lateral mass screw to a vertebral lateral mass or to
`mally invasive surgical apparatus having an instrument
`portal , an anchor pin receiving chamber , and a handle . The
`a thoracic or lumbar pedicle .
`instrument portal may comprise an instrument portal com
`BACKGROUND
`prising a first proximal end , a first distal end , and a first
`elongated member . The first elongated member may include
`The spine includes a plurality of vertebrae arranged in a
`a first cylindrical bore having a first diameter . The first
`vertical column . Traditionally , implant devices have been 15 cylindrical bore may extend from the first distal end to the
`used to secure bone or bone segments to promote the healing
`first proximal end .
`and repair of various parts of the human body . Between each
`The anchor pin receiving chamber may be fixed in parallel
`vertebra there is an intervertebral disc that provides a
`to the instrument portal . The anchor pin receiving chamber
`cushion between adjacent vertebrae and transmits force
`may include a second proximal end , a second distal end , and
`between adjacent vertebrae . Traditionally , degenerative disc 20 a second elongated member comprising a second cylindrical
`disease has been treated by surgically removing a diseased
`bore . The second cylindrical bore may extend from the
`disc and interesting an implant in the space vacated by the
`second distal end to the second proximal end . The second
`diseased disc . The implant may be bone or other biocom-
`diameter may be smaller than the first diameter . The handle
`patible implants . The adjacent vertebrae are then immobi
`may depend from a surface of the instrument portal or a
`lized relative to one another using pedicle screw or lateral 25 surface of the anchor pin receiving chamber .
`mass screw fixation . Subsequently , the adjacent vertebrae
`In certain example embodiments , the system and / or appa
`grow into one solid piece of bone over time . This process
`ratus further includes at least one or more of the following
`can include using a bone graft or bone graft substitute to
`devices : an inner cannula , an anchoring pin , a drill guide
`reducer , a drill guide , or a pedicle screw or lateral mass
`stabilize the vertebrae .
`Conventionally , spinal rods that immobilize vertebral 30 screw reducer .
`The details of one or more embodiments of the disclosure
`bones are typically anchored to the vertebrae through bone
`are set forth in the accompanying drawings and the descrip
`screws that extend through the pedicle or lateral mass into
`tion below . Other features , objects , and advantages of the
`vertebral bodies or bones by hooks that engage around the
`disclosure will be apparent from the description , drawings ,
`vertebrae . Spinal rods have been used , by connecting to the
`35 and from the claims .
`screws or anchor members by coupling members . While
`incisions are required during many surgical procedures to
`DESCRIPTION OF DRAWINGS
`gain access to the site , such incisions can cause injury to the
`patients ' body . To avoid unnecessary damage , small inci
`To facilitate an understanding of and for the purpose of
`sions are often preferred .
`40 illustrating the present disclosure , exemplary features and
`Many traditional approaches require the use of guidewires
`implementations are disclosed in the accompanying draw
`to set a pedicle screws or lateral mass screws to a vertebral
`ings , it being understood , however , that the present disclo
`sure is not limited to the precise arrangements and instru
`body prior to using some minimally invasive surgical ( MIS )
`mentalities shown , and wherein similar reference characters
`system to anchor the screw to the mass and perform a
`surgery . In one traditional approach , the MIS system uses at 45 denote similar elements throughout the several views , and
`least two pedicle anchors or screws , in which the screws are
`wherein :
`secured to the vertebrae by sliding the MIS device down a
`FIG . 1 is a perspective view of a MIS system that includes
`guidewire , like the MIS implant device described in U.S.
`a MIS apparatus and an inner cannula in accordance with the
`Patent App . No. 2012/0022597 . As described therein , the
`present disclosure ;
`procedure includes a surgeon inserting a Jamshidi needle 50
`FIG . 2 is another perspective view of a MIS system that
`percutaneously over the posterior spinal anatomy thereby
`includes a MIS apparatus and an inner cannula in accor
`creating a small incision . The Jamshidi needle is able to hold
`dance with the present disclosure ;
`the guidewire and is used to percutaneously force the
`FIG . 3 is another perspective view of a MIS system that
`guidewire into place . It is only after the guidewire is secured
`includes a MIS apparatus and an inner cannula in accor
`that a docking device is used to secure an anchor to a 55 dance with the present disclosure ;
`vertebral mass . Traditionally this
`done by sliding the
`FIG . 4 is a perspective view of a MIS system that includes
`docking device down the guidewire toward the pre - posi-
`a MIS apparatus and an anchor pin in accordance with the
`tioned guidewire path .
`present disclosure ;
`Thus , a need exists for a MIS system that can secure a
`FIG . 5 is a perspective view of a MIS system that includes
`pedicle screw or lateral mass screw to a vertebral mass of a 60 a MIS apparatus , an anchor pin , and a drill guide reducer in
`patient by anchoring itself to a vertebral mass without
`accordance with the present disclosure ;
`specifically requiring assistance by a guidewire . Moreover ,
`FIG . 6 is another perspective view of a MIS system that
`a need exists for a hand held device that includes an
`includes a MIS apparatus , an anchor pin , and a drill guide
`instrument portal for receiving a variety of instruments
`reducer in accordance with the present disclosure ;
`during a surgery and / or includes a docking mechanism to 65
`FIG . 7 is another perspective view of a MIS system that
`secure a screw , such as a polyaxial screw , to a vertebral
`includes a MIS apparatus , an anchor pin , and a drill guide
`lateral mass or pedicle .
`reducer in accordance with the present disclosure ;
`
`Globus Medical, Inc. Exhibit 2007, Page 9 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,179,144 B2
`
`a
`
`4
`3
`200 includes an instrument portal 205 , an anchor pin receiv
`FIG . 8 is a perspective view of an example MIS system
`ing chamber 235 , and a handle 265. As described in detail
`that includes a MIS apparatus , an anchor pin , a drill guide
`below , the instrument portal 205 is sized to receive various
`reducer , and a drill guide ;
`surgical instruments , in some embodiments the instrument
`FIG . 9 is a perspective view of an example MIS system
`that includes a MIS apparatus , an anchor pin , and a pedicle 5 portal receives various diameter reducers for example to
`meet the requirements of various surgical scenarios . In
`screw or lateral mass screw reducer ;
`FIG . 10 is another perspective view of an example MIS
`general , the MIS apparatus 200 can be secured to a vertebral
`system that includes a MIS apparatus , an anchor pin , and a
`lateral mass or vertebral pedicle via inserting a fastener into
`the anchor pin receiving chamber 235 , and once secured , a
`pedicle screw or lateral mass screw reducer ;
`FIG . 11 is another perspective view of an example MIS 10 screw can be inserted into the vertebral lateral mass or
`system that includes a MIS apparatus , an anchor pin , and a
`pedicle 900 via the instrument portal 205 and then the MIS
`apparatus 200 can be withdrawn and the screw left within
`pedicle screw or lateral mass screw reducer ;
`FIG . 12 is a partial cutaway view of the system of FIG . 11 ,
`the body . Various suitable types of screws can be used with
`wherein the view shows a pedicle screw or lateral mass
`the MIS system 200. Suitable types of screws can include ,
`15 for example , cervical lateral mass screws , such as posterior
`screw being inserted into the MIS apparatus ;
`FIG . 13 is another partial cutaway view of the system of
`cervical lateral mass screws , and thoracic and lumbar
`FIG . 11 , wherein the view shows a pedicle screw or lateral
`pedicle screws . In several embodiments described herein ,
`mass screw being screwed into a lateral vertebral mass ;
`the screw is described as a polyaxial pedicle screw or lateral
`FIG . 14 is an exploded view of the system of FIG . 11 ,
`mass screw , but the invention is not specifically limited to
`wherein the view shows a pedicle screw or lateral mass 20 such embodiments . One example of a suitable polyaxial
`screw can be the DENALI® Mini Polyaxial Screw having a
`screw being screwed into a lateral vertebral mass ;
`FIG . 15 is a perspective view of the system of FIG . 11 ,
`circumference of 3.5 millimeters and a length of 14 milli
`meters , which is sold by K2M Inc. Suitable screws can also
`wherein the view shows a pedicle screw or lateral mass
`have a variety of suitable screw head configurations , shapes ,
`screw being screwed into a lateral vertebral mass ;
`FIG . 16 is an exploded view of the system of FIG . 11 , 25 and sizes . For example , the screw can have a U - shaped or
`wherein the view shows a MIS apparatus being withdrawn
`tulip shaped head . In certain embodiments the screws
`described herein can include one or more guidewires con
`from a lateral vertebral mass .
`nected to the head of the screw , the guidewires being used
`to secure a rod to the screw 800 after the screw 800 has been
`DETAILED DESCRIPTION
`30 fixed to a vertebral mass . Other suitable screws as known to
`those having skill in the art can be use as well .
`The following is a description of several illustrations of
`In the example MIS apparatus 200 shown in FIG . 1 , the
`spinal fixation devices and methods for treating spinal
`injuries and abnormalities .
`instrument portal 205 of the MIS apparatus 200 includes a
`first proximal end 210 , a first distal end 215 , and a first
`Certain terminology is used herein for convenience only
`and is not to be taken as a limitation on the present invention . 35 elongated member 220. The first elongated member 220
`In the drawings , the same reference numbers are employed
`includes a first cylindrical bore 225 having a first diameter
`for designating the same elements throughout the several
`230. The first cylindrical bore 225 can be used to receive a
`figures . A number of examples are provided , nevertheless , it
`variety of different tools , instruments , accessories , and / or
`will be understood that various modifications can be made
`devices for performing a MIS surgery . For example , the first
`without departing from the spirit and scope of the disclosure 40 cylindrical bore 225 can receive various types of surgical
`herein . As used in the specification , and in the appended
`instruments , for example , the first cylindrical bore 255 can
`claims , the singular forms “ a , " " an , ” “ the ” include plural
`receive any of the following instruments described in further
`referents unless the context clearly dictates otherwise . The
`detail below : an inner cannula 300 , a drill guide reducer 500 ,
`term " comprising ” and variations thereof as used herein is
`a drill guide 600 , a pedicle screw or lateral mass screw
`used synonymously with the term “ including ” and variations 45 reducer 700 , and / or a pedicle screw or lateral mass screw
`thereof and are open , non - limiting terms . Although the terms
`800. In certain embodiments , the first diameter 230 of the
`" comprising ” and “ including ” have been used herein to
`first cylindrical bore 225 is about 12 millimeters , but as
`describe various embodiments , the terms " consisting essen-
`described below this working diameter can essentially be
`tially of ” and “ consisting of ” can be used in place of
`changed through the introduction of various types of reduc
`" comprising ” and “ including ” to provide for more specific 50 ers , like the drill guide reducer 500 or the pedicle screw or
`lateral mass screw reducer 700 described below . The first
`embodiments of the invention and are also disclosed .
`The present invention now will be described more fully
`cylindrical bore 225 can extend a distance from the first
`distal end 215 to the first proximal end 210. In certain
`hereinafter with reference to specific embodiments of the
`invention . Indeed , the invention can be embodied in many
`embodiments this distance traverses the entire first elongated
`different forms and should not be construed as limited to the 55 member 220 , but in certain embodiments the distance tra
`embodiments set forth herein ; rather , these embodiments are
`versed need not be continuously connected nor encompass
`provided so that this disclosure will satisfy applicable legal
`the entire length of the first elongated member 220. More
`requirements .
`over , in certain embodiments the first diameter 230 may vary
`FIG . 1 illustrates an example of a minimally invasive
`as it traverses the first elongated member 220 .
`surgical ( MIS ) system 100 that includes a MIS apparatus 60
`In certain embodiments , the instrument portal 205 can be
`200 for securing a pedicle screw or lateral mass screw to a
`radiolucent so that the position of instruments situated
`vertebral lateral mass 900 in accordance with the present
`within the instrument portal 205 can be accurately ascer
`disclosure ( FIGS . 13-16 depict the vertebral lateral mass
`tained during surgery . One such way of ascertaining the
`900 ) . The MIS system 100 has the ability to anchor itself to
`position of instruments is via an X - ray machine . In certain
`a lateral vertebral mass 900 and secure a screw to the lateral 65 embodiments , the first distal end 215 of the instrument portal
`vertebral mass or vertebral pedicle without needing the use
`205 comprises an oblique end that is contoured to fit against
`of a guidewire . In many embodiments , the MIS apparatus
`the lateral mass 900. This allows for easier insertion of a
`
`>
`
`>
`
`Globus Medical, Inc. Exhibit 2007, Page 10 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,179,144 B2
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`a
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`In certain embodiments , the MIS system 100 includes an
`polyaxial screw into a lateral vertebral mass . In certain
`inner cannula 300 , which can be inserted into the instrument
`embodiments the oblique end can form an angle 227 of
`portal 205 of the MIS apparatus 200 for dilating , cutting ,
`about 45 degrees .
`and / or stretching bodily tissue and / or bone when advancing
`In the example MIS apparatus 200 shown in FIG . 1 , the
`anchor pin receiving chamber 235 of the MIS apparatus 2005 the MIS apparatus 200 toward a lateral mass 900. FIGS . 2-3
`illustrate one such embodiment . The inner cannula 300
`includes a second proximal end 240 , a second distal end 245 ,
`includes a proximal end 310 , a distal end 315 , and an
`and a second elongated member 250. The second elongated
`elongated member 320 having an outer diameter 325 sized
`member 250 includes a second cylindrical bore 255 having
`a
`to fit within the instrument portal 205. In certain embodi
`a second diameter 260. In certain embodiments the second
`diameter 260 of the second cylindrical bore 255 is smaller 10 ments the outer diameter 325 of the inner cannula 300 is
`sized to fit against the first diameter of the first cylindrical
`than the first diameter 230 of the first cylindrical bore 225 .
`bore 225. In certain embodiments the distal end 315 of the
`In certain embodiments the second diameter 260 can range
`inner cannula 300 is tapered , which can act as a wedge to
`from about 1 millimeter to about 6 millimeters . In certain
`assist in the traversal of the MIS apparatus 200 toward the
`embodiments , the second diameter is about 2 millimeters . 15 lateral mass 900. In certain embodiments , the inner cannula
`The second cylindrical bore 255 can extend a distance from
`300 include an inner bore ( not shown ) that traverses the
`the second distal end 245 to the second proximal end 240 .
`length of the elongated member 320 so that fluid and body
`In certain embodiments this distance traverses the entire
`tissue can be sucked out or withdrawn from the body as the
`second elongated member 250 , but in certain embodiments
`MIS apparatus 200 traverses toward the vertebral lateral
`the distance traversed need not be continuously connected 20 mass 900. In certain embodiments the tapered distal end 315
`nor encompass the entire length of the second elongated
`is conical and / or wedge shaped . In certain embodiments a
`member 250. Moreover , in certain embodiments the second
`surface of the elongated member 320 can include threads ,
`diameter 260 may vary as it traverses the second elongated
`grips , or other means for creating a friction fit between the
`elongated member 320 and the first cylindrical bore 225 .
`member 250 .
`FIG . 1 shows the anchor pin receiving chamber 235 as 25
`In certain embodiments the inner cannula 300 is
`radiopaque so that the position of inner cannula 300 can be
`being fixed in parallel to the instrument portal 205. The
`anchor pin receiving chamber 235 can be fixed to the MIS
`seen by an X - ray machine when it's within the instrument
`apparatus 200 in a variety of suitable ways . For example , the
`portal 205. In such embodiments , the instrument portal 205
`fixture can be a permanent fixture such as an adhesive , glue ,
`can be radiolucent .
`welding joint , or other suitable long - lasting and / or perma- 30
`In certain embodiments , the MIS system 100 includes an
`nent fastener . The fixture can also be created by integrally
`anchor pin 400. As illustrated in FIG . 4 , the anchor pin 400
`molding the anchor pin receiving chamber 235 and the
`can be inserted into the anchor pin receiving chamber 235 to
`instrument portal 205 together . In such integral molding , the
`anchor the MIS apparatus 200 to a vertebral lateral mass
`anchor pin receiving chamber 235 and the instrument portal
`900. In certain embodiments the anchor pin 400 includes an
`205 can comprise two parts of a larger frame . For example , 35 elongated member 405 , a proximal stopping knob 410 , and
`the anchor pin receiving chamber 235 and the instrument
`a proximal protruding end 415. When the anchor pin 400 is
`portal 205 can be two barrels of a larger solid structure . The
`located within the anchor pin receiving chamber 235 , the
`outer surfaces of the pin receiving chamber 235 and the
`proximal protruding end 415 extends a distance past the
`instrument portal 205 need not me cylindrical in several of
`second distal end . One suitable distance is about 12 milli
`the embodiments herein . The fixture can also be created 40 meters . It should be understood that in certain embodiments
`through the use of a releaseably coupleable fastener , like a
`more than one anchor pin 400 may be used in one or more
`a
`zipper , clamp , bracket , or clip . Other suitable means for
`anchor pin receiving chambers 235 .
`fixing can be used as known to those having ordinarily skill
`In certain embodiments , the MIS system 100 includes a
`in the art . Although the figures show the MIS apparatus 200
`drill guide reducer 500. As illustrated in FIGS . 5-8 , the drill
`as comprising a single anchor pin receiving chamber 235 , it 45 guide reducer 500 can be inserted into the instrument portal
`should be understood that other numbers of anchor pin
`205 of the MIS apparatus 200 to accommodate a diameter
`receiving chambers 235 and / or other numbers of anchor pins
`605 of a drill guide 600 used to drill a hole into a vertebral
`can be included in the MIS apparatus 200. For example , in
`lateral mass 900. In certain embodiments the drill guide
`certain embodiments two or more anchor pin receiving
`reducer 500 includes an elongated cylindrical member 510
`chambers 235 are fixed to a single instrument receiving 50 having an outer diameter 515 sized to fit within the instru
`ment portal 205 and an inner diameter 520 sized to fit the
`chamber 205 .
`In the example MIS apparatus 200 shown in FIG . 1 , the
`diameter 605 of the drill guide 600. In certain embodiments ,
`the diameter 605 of the drill guide 600 is smaller than the
`MIS apparatus 200 includes a handle 265 depending from a
`surface of the anchor pin receiving chamber 235. In certain
`first diameter 230. In certain embodiments , the inner diam
`embodiments the handle depends from another surface such 55 eter 520 of the drill guide reducer 500 ranges from about
`as a surface of the instrument portal 205. In embodiments
`1.75 millimeters to about 3.25 millimeters . In certain
`where the anchor pin receiving chamber 235 and the instru-
`embodiments , the inner diameter 520 of the drill guide
`ment portal 205 are integrally formed , the handle 265 can be
`reducer 500 is about 3 millimeters . In certain embodiments ,
`fixed to a surface of the integrally formed structure . The
`a surface of the elongated member 510 can include threads ,
`handle 265 is designed for gripping of the MIS apparatus 60 grips , or other means for creating a friction fit between the
`200. In certain embodiments the handle 265 includes various
`elongated member 510 and the first cylindrical bore 225 .
`grooves or indents to receive corresponding fingers . The
`In certain embodiments , the MIS system 100 includes a
`handle 265 can take the form of various suitable shapes .
`pedicle screw or lateral mass screw reducer 700. As illus
`Some suitable types of shapes include cubes , rectangular
`trated in FIGS . 9-17 , the pedicle screw or lateral mass screw
`prisms , and cylinders . Other suitable shapes and configura- 65 reducer 700 can be inserted into the instrument portal 205 of
`tions for the handle 265 can be used as known to those
`the MIS apparatus 200 to accommodate a diameter of a head
`of the pedicle screw or lateral mass screw 800. In certain
`having skill in the art .
`
`Globus Medical, Inc. Exhibit 2007, Page 11 of 14
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,179,144 B2
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`2
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`2
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`pedicle screw or lateral mass screw 800 into the instrument
`embodiments , the pedicle screw or lateral mass screw
`portal 205 includes inserting the pedicle screw or lateral
`reducer 700 includes an elongate cylindrical member 710
`mass screw 800 into the pedicle screw or lateral mass screw
`having an outer diameter 715 sized to fit within the instru-
`reducer 700 as shown in FIG . 12. In certain embodiments the
`ment portal 205 and an inner diameter 720 sized to fit the
`diameter of the pedicle screw or lateral mass screw head.5 step of screwing the pedicle screw or lateral mass screw 800
`The diameter of the head of the pedicle screw or lateral mass
`into the vertebral lateral mass or pedicle 900 includes
`screw is smaller than the first diameter . In certain embodi-
`screwing the pedicle screw or lateral mass screw 800 into the
`ments , the inner diameter 720 of the pedicle screw or lateral
`hole of the vertebral lateral mass or pedicle 900 through the
`mass screw reducer 700 ranges from about 7 millimeters to
`pedicle screw or lateral mass screw reducer 700 , an example
`about 12 millimeters . In certain embodiments a surface of 10 of which is shown in the transition from FIG . 13 to FIG . 15 .
`the elongated member 710 can include threads , grips , or
`The method can further include removing the anchor pin 400
`other means for creating a friction fit between the elongated
`from the anchor pin receiving chamber 235 and withdrawing
`member 710 and the first cylindrical bore 225 .
`the MIS apparatus 200 away from the vertebral lateral mass
`Although the MIS system 100 is described as including a
`or pedicle 900 , an example of which is shown in FIG . 16 .
`MIS apparatus 200 and one or more of the above devices 15
`The MIS apparatus 200 and the various components
`( e.g. , inner cannula 300 , anchor pin 400 , drill guide reducer
`described above can be created from various types of
`500 , drill guide 500 , pedicle screen reducer 700 , etc. ) , it
`suitable materials , for example , biocompatible materials like
`should be understood that the MIS apparatus 200 can be
`titanium and polyethylene ketone . The parts can be created
`described as further comprising within itself one or more of
`through 3D printing and / or through other processes that are
`the various other devices at different points in time . For 20 known to those having ordinary skill in the art .
`example , in one embodiment the MIS apparatus 200 may
`A number of embodiments of the invention have been
`include an instrument portal 205 , a pedicle screw or lateral
`described . Nevertheless , it will be understood that various
`mass screw reducer 700 located within the instrument portal
`modifications may be made without departing from the spirit
`205 , an anchor pin receiving chamber 235 fixed in parallel
`and scope of