US011304818B2
`
`( 12 ) United States Patent
`Butler et al .
`
`US 11,304,818 B2
`( 10 ) Patent No .:
`( 45 ) Date of Patent :
`Apr. 19 , 2022
`
`( 54 ) EXPANDABLE SPINAL INTERBODY
`ASSEMBLY
`( 71 ) Applicant : Life Spine , Inc. , Huntley , IL ( US )
`( 72 ) Inventors : Michael S. Butler , St. Charles , IL
`( US ) ; Madeline Wolters , Carol Stream ,
`IL ( US ) ; Daniel Predick , West
`Lafayette , IN ( US )
`( 73 ) Assignee : Life Spine , Inc. , Huntley , IL ( US )
`Subject to any disclaimer , the term of this
`( * ) Notice :
`patent is extended or adjusted under 35
`U.S.C. 154 ( b ) by 157 days .
`( 21 ) Appl . No .: 16 / 009,616
`( 22 ) Filed :
`Jun . 15 , 2018
`( 65 )
`
`Prior Publication Data
`Oct. 18 , 2018
`US 2018/0296361 A1
`Related U.S. Application Data
`( 63 ) Continuation - in - part of application No. 15 / 497,011 ,
`)
`filed on Apr. 25 , 2017 , now Pat . No. 10,383,741 ,
`( Continued )
`
`( 51 ) Int . Ci .
`A61F 2/44
`A61F 2/30
`A61B 17/88
`( 52 ) U.S. CI .
`CPC
`
`( 2006.01 )
`( 2006.01 )
`( 2006.01 )
`A61F 2/4425 ( 2013.01 ) ; A61B 17/8858
`( 2013.01 ) ; A61F 2/30771 ( 2013.01 ) ;
`( Continued )
`( 58 ) Field of Classification Search
`A61F 2/4455
`CPC
`See application file for complete search history .
`
`( 56 )
`
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`( Continued )
`FOREIGN PATENT DOCUMENTS
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`.
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`Search Report for International Application No. PCT / US2018 /
`041306 , dated Sep. 28 , 2018 , 12 pages .
`( Continued )
`Primary Examiner — David W Bates
`( 74 ) Attorney , Agent , or Firm - Foley & Lardner LLP
`( 57 )
`ABSTRACT
`An expandable implant includes a top support assembly
`defining an upper surface configured to engage a first portion
`of bone , a first central aperture extending from the upper
`surface to an interior of the implant , and a first grid structure
`surrounding the first central aperture ; a bottom support
`assembly defining a lower surface configured to engage a
`second portion of bone , a second central aperture extending
`from the lower surface to the interior , and a second grid
`structure surrounding the second central aperture ; and a
`control assembly coupled to the top support assembly and
`the bottom support assembly and configured to control
`relative movement between the top support assembly and
`the bottom support assembly between a collapsed position
`and an expanded position .
`13 Claims , 42 Drawing Sheets
`
`218
`
`220
`
`212
`
`224
`
`724
`
`726
`
`230
`
`216
`
`ODZE AL 238
`
`-214
`
`234
`
`232
`
`735
`
`736
`
`712
`
`718
`
`738
`714
`
`740
`
`744
`
`742
`
`720
`
`Globus Medical, Inc. Exhibit 2006, Page 1 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,304,818 B2
`Page 2
`
`Related U.S. Application Data
`which is a continuation - in - part of application No.
`14 / 714,821 , filed on May 18 , 2015 , now Pat . No.
`9,801,733 , which is a continuation - in - part of appli
`cation No. 13 / 802,110 , filed on Mar. 13 , 2013 , now
`Pat . No. 9,034,041 .
`
`A61L 27/58
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`Globus Medical, Inc. Exhibit 2006, Page 2 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,304,818 B2
`Page 3
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`Globus Medical, Inc. Exhibit 2006, Page 3 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,304,818 B2
`Page 4
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`A61F 2/447
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`WO 2006/105437 A2
`WO 2009/124269
`WO - 2014 / 134590 A1
`WO - 2014 / 165319 Al
`WO 2016/077610 A1
`
`6/2016
`5/2019
`9/2006
`10/2006
`10/2009
`9/2014
`10/2014
`5/2016
`
`WO
`WO
`WO
`WO
`
`WO 2016/127139 Al
`WO 2017/027873 A1
`WO 2017/066463 A1
`WO - 2019 / 014139 A1
`
`8/2016
`2/2017
`4/2017
`1/2019
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`
`Globus Medical, Inc. Exhibit 2006, Page 4 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 1 of 42
`
`US 11,304,818 B2
`
`13
`
`15
`
`10
`
`P
`
`A
`
`17
`
`a
`
`FIG . 1
`
`Globus Medical, Inc. Exhibit 2006, Page 5 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 2 of 42
`
`US 11,304,818 B2
`
`10
`
`18
`
`14
`
`11
`
`20
`
`12
`
`FIG . 2
`
`12
`
`48
`
`50
`
`18
`
`A
`
`14
`
`( ) A
`
`22
`
`9
`22
`
`-14
`
`IE
`
`FIG . 3
`
`12
`
`76
`
`78
`
`18
`
`20
`
`FIG . 4
`16
`
`FIG . 5
`
`14
`
`12
`
`52 FIG . 6
`
`1
`
`
`
`more than
`
`- 7
`11
`
`30
`
`??
`
`12
`
`16
`
`14
`
`18
`
`you
`
`24
`
`content
`
`FIG . 7
`
`20
`
`46
`
`Globus Medical, Inc. Exhibit 2006, Page 6 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 3 of 42
`
`US 11,304,818 B2
`
`18
`
`14
`
`20
`FIG . 8
`
`18
`
`my
`
`14
`
`16
`
`18
`
`.12
`
`12
`
`20
`FIG . 9
`
`20
`
`FIG . 10
`
`12
`
`12
`
`FIG . 12
`18
`
`FIG . 13
`
`20
`
`18
`
`14
`
`14
`
`16
`
`18
`
`14
`
`?
`
`20
`FIG . 11
`
`Globus Medical, Inc. Exhibit 2006, Page 7 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 4 of 42
`
`US 11,304,818 B2
`
`22
`
`d 70
`
`64
`
`56
`
`59
`66
`
`24
`
`40 44
`AO AA
`
`36
`
`72
`
`74
`38
`
`14
`
`108
`106
`
`42
`
`58
`
`62
`
`68
`18
`104
`
`16
`22 102 84 92
`87
`
`98
`
`22
`
`60
`54
`
`30
`
`26
`
`12
`
`20
`
`88
`
`86 80 .
`
`100
`
`90
`
`FIG . 14
`
`94
`20
`
`96
`
`22 to
`
`Globus Medical, Inc. Exhibit 2006, Page 8 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 5 of 42
`
`US 11,304,818 B2
`
`46
`
`14
`
`60
`
`FIG . 15
`( A - A )
`
`16
`
`62
`
`12
`
`Globus Medical, Inc. Exhibit 2006, Page 9 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr.19 , 2022
`
`Sheet 6 of 42
`
`US 11,304,818 B2
`
`118
`116
`
`114
`
`152
`
`120
`
`150
`
`111
`
`112
`
`FIG.16
`
`112
`
`118
`
`120
`
`FIG . 17
`
`114
`
`116
`
`Globus Medical, Inc. Exhibit 2006, Page 10 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 7 of 42
`
`US 11,304,818 B2
`
`152
`
`118
`
`112
`
`150
`
`120
`
`FIG . 18
`
`112
`
`152
`
`116
`
`118
`
`114
`
`114
`
`150
`
`FIG . 19
`
`Globus Medical, Inc. Exhibit 2006, Page 11 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 8 of 42
`
`US 11,304,818 B2
`
`148
`
`150
`
`118
`
`?
`
`114
`
`112
`
`176
`
`120
`
`FIG . 20
`
`118
`
`114
`
`112
`
`120
`
`FIG . 21
`
`118
`
`wo
`wm
`Li
`
`FIG . 22
`
`114 124
`
`mm
`KUW
`
`116
`
`112
`
`120
`
`Globus Medical, Inc. Exhibit 2006, Page 12 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 9 of 42
`
`US 11,304,818 B2
`
`156
`
`154 118
`
`112
`
`114
`
`120
`
`150
`
`FIG . 23
`
`118
`
`154
`
`112
`
`114
`
`120
`
`150
`
`FIG . 24
`
`Globus Medical, Inc. Exhibit 2006, Page 13 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 10 of 42
`
`US 11,304,818 B2
`
`118
`
`114
`
`120
`
`112
`
`112
`
`118
`
`FIG . 25
`
`152
`
`150
`
`FIG . 26
`
`Globus Medical, Inc. Exhibit 2006, Page 14 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 11 of 42
`
`US 11,304,818 B2
`
`112
`
`112
`
`118
`
`114
`
`120
`
`FIG . 27
`
`118
`
`114
`
`FIG . 28
`
`120
`
`Globus Medical, Inc. Exhibit 2006, Page 15 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 12 of 42
`
`US 11,304,818 B2
`
`118 ?
`
`114
`- 116
`
`124
`
`112
`
`120
`
`FIG . 29
`
`164 159
`166
`140114
`
`116
`
`01 ) D ) ©
`
`124
`
`156
`
`118
`154
`
`152
`150
`
`160
`
`158
`162
`
`112
`
`120
`
`FIG . 30
`
`Globus Medical, Inc. Exhibit 2006, Page 16 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 13 of 42
`
`US 11,304,818 B2
`
`218
`
`210
`
`218
`
`214
`
`212
`
`214
`
`224
`
`216
`
`ton
`220
`
`FIG . 31
`
`218
`
`220
`
`220
`
`FIG . 32
`
`224
`
`232
`
`216
`
`230
`
`238
`
`-214
`
`234
`
`FIG . 33
`
`212
`
`212
`
`Globus Medical, Inc. Exhibit 2006, Page 17 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 14 of 42
`
`US 11,304,818 B2
`
`218
`
`212
`
`FIG . 34
`
`216
`
`238
`
`216
`
`234
`
`232
`
`FIG . 35
`
`236
`
`FIG . 36
`
`Globus Medical, Inc. Exhibit 2006, Page 18 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 15 of 42
`
`US 11,304,818 B2
`
`238
`
`236
`
`FIG . 37
`
`w
`
`238
`
`236
`
`FIG . 38
`
`Globus Medical, Inc. Exhibit 2006, Page 19 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 16 of 42
`
`US 11,304,818 B2
`
`260
`
`268
`
`266
`
`264
`
`262
`
`270
`
`FIG . 39
`
`Globus Medical, Inc. Exhibit 2006, Page 20 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 17 of 42
`
`US 11,304,818 B2
`
`268
`
`266
`
`274
`
`280
`
`264
`
`284
`
`286
`288 282
`
`262
`
`270
`
`FIG . 40
`
`296
`
`268
`
`262
`
`270
`
`FIG . 41
`
`264
`
`296
`
`Globus Medical, Inc. Exhibit 2006, Page 21 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 18 of 42
`
`US 11,304,818 B2
`
`264 T KU DUDE
`
`FIG . 42
`
`268
`
`268
`
`262
`
`262
`
`262
`
`>
`. 264
`
`~
`
`264
`
`274
`
`d
`270
`
`FIG . 43
`
`268
`
`266
`
`Tratament
`you milli
`
`270
`
`FIG . 44
`
`Globus Medical, Inc. Exhibit 2006, Page 22 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 19 of 42
`
`US 11,304,818 B2
`
`260
`
`292
`
`268
`
`264
`
`262
`
`290
`
`294
`
`270
`
`294
`
`FIG . 45
`
`268
`
`?
`
`ZIECI LLLL
`LE
`
`262
`
`264
`
`292
`
`FIG . 46
`
`270
`
`Globus Medical, Inc. Exhibit 2006, Page 23 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 20 of 42
`
`US 11,304,818 B2
`
`314
`
`318
`
`310
`
`-330
`
`( RS
`
`320
`
`332
`
`FIG . 47
`
`314
`
`318
`
`310
`
`332
`
`334
`
`320
`
`FIG . 48
`
`334
`
`330
`
`312
`
`314
`
`Globus Medical, Inc. Exhibit 2006, Page 24 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 21 of 42
`
`US 11,304,818 B2
`
`310
`
`318
`
`-330
`
`316
`
`314
`
`312
`
`332
`
`FIG . 49
`
`Globus Medical, Inc. Exhibit 2006, Page 25 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 22 of 42
`
`US 11,304,818 B2
`
`-360
`
`364
`
`360
`
`-382
`
`368
`
`384
`
`370
`
`1A
`
`FIG . 50
`
`384
`
`368
`
`380
`
`A
`
`364
`
`370
`
`FIG . 51
`
`Globus Medical, Inc. Exhibit 2006, Page 26 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 23 of 42
`
`US 11,304,818 B2
`
`362
`
`368
`
`380
`
`370
`
`360
`
`304
`
`A
`
`360
`
`382
`
`364
`
`FIG . 52
`
`A
`
`FIG . 53
`
`Globus Medical, Inc. Exhibit 2006, Page 27 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 24 of 42
`
`US 11,304,818 B2
`
`416
`
`-410
`
`418
`
`412
`
`414
`
`-410
`
`.414
`
`420
`
`FIG . 54
`
`418
`
`412
`
`431
`
`420
`
`FIG . 55
`
`Globus Medical, Inc. Exhibit 2006, Page 28 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 25 of 42
`
`US 11,304,818 B2
`
`418
`
`412
`
`414
`
`FIG . 56
`
`418
`
`414
`420
`
`MO
`
`FIG . 57
`
`Globus Medical, Inc. Exhibit 2006, Page 29 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 26 of 42
`
`US 11,304,818 B2
`
`426
`
`418
`
`421
`
`...
`
`412
`
`425
`
`420
`
`423
`FIG . 58
`
`428
`
`414
`
`427
`
`Globus Medical, Inc. Exhibit 2006, Page 30 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 27 of 42
`
`US 11,304,818 B2
`
`-410
`
`418
`
`420
`
`414
`
`412
`
`FIG . 59
`
`420
`
`418
`
`FIG . 60
`
`Globus Medical, Inc. Exhibit 2006, Page 31 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 28 of 42
`
`US 11,304,818 B2
`
`416
`
`414
`
`424 422
`
`418
`
`420
`
`FIG . 61
`
`412
`
`Globus Medical, Inc. Exhibit 2006, Page 32 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 29 of 42
`
`US 11,304,818 B2
`
`434
`
`416
`438 430
`432
`
`438
`
`436
`
`FIG . 62
`
`436
`FIG . 63
`
`436
`
`FIG . 64
`
`in
`
`438
`
`432
`
`436
`
`FIG . 65
`
`Globus Medical, Inc. Exhibit 2006, Page 33 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 30 of 42
`
`US 11,304,818 B2
`
`490
`
`462
`
`ID
`
`460
`
`490
`
`-464
`
`FIG . 66
`
`468
`
`462
`
`470
`
`464
`
`FIG . 67
`
`Globus Medical, Inc. Exhibit 2006, Page 34 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 31 of 42
`
`US 11,304,818 B2
`
`LUGET
`
`468
`
`470
`
`464
`
`FIG . 68
`
`462
`
`470
`
`492
`
`492
`
`FIG . 69
`
`Globus Medical, Inc. Exhibit 2006, Page 35 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 32 of 42
`
`US 11,304,818 B2
`
`468
`
`472
`
`494
`
`474
`
`464
`
`462
`
`496
`
`470
`
`466 488
`480 486
`
`484
`
`482
`
`FIG . 70
`
`Globus Medical, Inc. Exhibit 2006, Page 36 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 33 of 42
`
`US 11,304,818 B2
`
`518
`
`510
`
`512
`
`512
`
`518
`
`522
`
`514
`
`520
`
`514
`
`544
`
`520
`
`FIG . 71
`
`524
`
`542
`
`FIG . 72
`
`Globus Medical, Inc. Exhibit 2006, Page 37 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 34 of 42
`
`US 11,304,818 B2
`
`524
`
`514
`
`522
`
`512
`
`544
`
`542
`
`FIG . 73
`
`Globus Medical, Inc. Exhibit 2006, Page 38 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 35 of 42
`
`US 11,304,818 B2
`
`524
`
`526
`
`532
`
`528
`562
`
`536 .
`
`512
`
`556
`
`552
`
`542 Q 548
`
`546
`
`530
`
`534
`
`tott 524
`
`538
`514
`
`540 566
`564 560
`
`576
`
`516
`574
`
`570
`
`572
`
`568
`
`-558
`
`554
`544
`
`ox 550
`
`FIG . 74
`
`Globus Medical, Inc. Exhibit 2006, Page 39 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 36 of 42
`
`US 11,304,818 B2
`
`522
`
`524
`
`514
`
`512
`
`542
`
`544
`
`FIG . 75
`
`Globus Medical, Inc. Exhibit 2006, Page 40 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 37 of 42
`
`US 11,304,818 B2
`
`610
`
`618
`
`614
`
`FIG . 76
`
`624
`
`614
`
`FIG . 77
`
`612
`
`612
`
`620
`
`622
`
`640
`
`622
`
`624
`
`614
`
`FIG . 78
`
`626
`
`612
`
`642
`
`640
`
`Globus Medical, Inc. Exhibit 2006, Page 41 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 38 of 42
`
`US 11,304,818 B2
`
`617
`
`622
`
`668
`
`676 -
`
`612
`
`638
`
`670
`
`FIG . 79
`
`624 616
`
`615
`
`H
`17 672
`
`674
`
`640 614
`
`626
`
`f
`
`617
`
`622
`t
`
`624
`
`616
`
`615
`
`? ?
`
`642 638
`
`617
`
`0001
`
`FIG . 80
`
`640
`
`622
`t
`
`andet
`
`624
`
`616
`
`615
`
`638
`
`FIG . 81
`
`640
`
`Globus Medical, Inc. Exhibit 2006, Page 42 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 39 of 42
`
`US 11,304,818 B2
`
`622
`
`634
`
`617
`
`630
`
`654
`
`va
`
`628
`
`656
`
`612
`
`644 652
`
`626 636 624
`Ž 632
`
`658
`
`-614
`660
`615
`
`616
`
`642
`
`646
`
`C
`
`640
`
`648
`
`650
`
`638
`
`FIG . 82
`
`Globus Medical, Inc. Exhibit 2006, Page 43 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 40 of 42
`
`US 11,304,818 B2
`
`622
`
`624
`
`614
`
`615
`
`616
`
`626 ,
`
`612
`
`617
`
`676
`
`640
`
`642 SHF 638
`
`FIG . 83
`
`654
`
`FIG . 84
`
`650
`
`652
`
`Globus Medical, Inc. Exhibit 2006, Page 44 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 41 of 42
`
`US 11,304,818 B2
`
`724
`
`726
`
`721
`
`735
`
`736
`
`712
`
`737
`
`723
`
`710
`
`718
`
`714
`
`738
`
`740
`
`744
`
`FIG . 85
`
`720
`
`742
`
`710
`
`731
`
`720
`
`740
`
`712
`
`714
`
`? ?
`
`the ci cetes anno
`
`742
`
`?? ? --
`de tracta de
`
`718
`
`736
`
`738
`FIG . 86
`
`Globus Medical, Inc. Exhibit 2006, Page 45 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`U.S. Patent
`
`Apr. 19 , 2022
`
`Sheet 42 of 42
`
`US 11,304,818 B2
`
`724
`
`726
`
`735
`
`736
`
`712
`
`740
`
`744
`FIG . 87
`
`718
`
`738
`714
`
`1
`
`742
`
`720
`
`721
`
`732
`
`734
`
`718
`
`714 e 712
`
`OCO
`
`DOO
`
`730 728
`
`731
`
`716
`
`FIG . 88
`
`Globus Medical, Inc. Exhibit 2006, Page 46 of 59
`Life Spine, Inc. v. Globus Medical, Inc.
`IPR2022-01602
`
`

`

`US 11,304,818 B2
`
`a
`
`20
`
`1
`EXPANDABLE SPINAL INTERBODY
`ASSEMBLY
`
`2
`wherein in the expanded position , a portion of the upper
`surface extends at an acute angle relative to a portion of the
`lower surface .
`Another embodiment relates to an expandable implant
`CROSS - REFERENCE TO RELATED PATENT
`5 comprising a top support assembly defining an upper surface
`APPLICATIONS
`configured to engage a first portion of vertebral bone ; a
`bottom support assembly defining a lower surface config
`This application is a continuation - in - part of U.S. appli
`ured to engage a second portion of vertebral bone ; a first
`cation Ser . No. 15 / 497,011 , filed Apr. 25 , 2017 , which is a
`wedge member slidably coupled to the top and bottom
`continuation - in - part of U.S. application Ser . No. 14/714 ,
`821 , filed May 18 , 2015 , which is a continuation - in - part of 10 support assemblies ; a second wedge member slidably
`coupled to the top and bottom support assemblies ; and a
`U.S. application Ser . No. 13 / 802,110 , filed Mar. 13 , 2013 , all
`control assembly coupled to the first and second wedge
`of which are incorporated herein by reference in their
`members and configured to control relative movement
`entireties . This application is related to U.S. application Ser .
`between the top support assembly and the bottom support
`No. 15 / 497,044 , filed Apr. 25 , 2017 and U.S. application Ser . 15 assembly between a collapsed position and an expanded
`No. 15 / 645,179 , filed Jul . 10 , 2017 , both of which are
`position ; wherein in the collapsed position , the upper surface
`incorporated herein by reference in their entireties .
`is generally parallel to the lower surface , and wherein in the
`expanded position , a portion of the upper surface extends at
`BACKGROUND
`an angle relative to a portion of the lower surface .
`Another embodiment relates to a method of using an
`expandable implant , comprising providing an expandable
`The present disclosure relates to implants such as spinal
`implant comprising a top support assembly , a bottom sup
`interbody and intravertebral body devices and , more par-
`ticularly , to vertebral interbody and intravertebral devices
`port assembly , and a control assembly coupled to the top and
`and other implants that are expandable after spinal place-
`bottom support assemblies ; manipulating the control assem
`25 bly in a first manner to move the top support assembly in a
`ment thereof .
`Fusion cages , as well as other types of bodies and / or
`linear fashion relative to the bottom support assembly ; and
`devices , are frequently utilized in spinal surgery inside a
`manipulating the control assembly in a second manner to
`vertebra ( intravertebral ) and / or between vertebrae of a
`move at least a portion of the top support assembly in a
`patient ( interbody ) . With interbody devices , one or more
`non - linear fashion relative to at least a portion of the bottom
`such spinal bodies are placed between vertebrae to provide 30 support assembly .
`Another embodiment relates to an expandable implant ,
`support and promote fusion between adjacent vertebrae
`where such is necessary due to disease