Name:
`
`Position:
`
`University of California, San Francisco
`CURRICULUM VITAE
`Aleksandar Rajkovic, MD, PhD
`
`Professor In Residence, Step 5
`Pathology
`School of Medicine
`
`Address:
`
`University of California, San Francisco
`Email: aleks.rajkovic@ucsf.edu
`
`EDUCATION
`1981 - 1985
`
`1985 - 1992
`
`Johns Hopkins University,
`Baltimore, Maryland
`Case Western Reserve
`University, Cleveland,
`Ohio
`1992 - 1993 Metrohealth Medical
`Center, Cleveland, Ohio
`
`1993 - 1997 Metrohealth Medical
`Center, Cleveland, Ohio
`1997 - 1997 Metrohealth Medical
`Center, Cleveland, Ohio
`Baylor College of
`Medicine
`
`1997 - 1999
`
`BS
`
`Chemistry
`
`MD/PHD
`
`Medicine/Molecular
`Biology
`
`Fritz
`Rottman
`
`Internship,
`General
`Medicine
`Residency
`
`Fellowship
`
`Medical Genetic
`Residency
`
`Internal Medicine
`
`Obstetrics and
`Gynecology
`Maternal Fetal
`Medicine
`Medical Genetics
`
`LICENSES, CERTIFICATION
`1993
`Medical License, State of OHIO
`1997
`Medical License, State of TEXAS
`2000
`Board Certified in Obstetrics and Gynecology, ID number 970717
`2002
`Board Certified in Clinical Genetics, ID number 749109
`2009
`Medical License, State of PENNSYLVANIA
`2012
`American Board of Medical Genetics, Certificate # 2002142
`2018
`Medical License, State of CALIFORNIA, C155309
`2023
`Medical License, State of CALIFORNIA, C155309
`
`TwinStrand EX1100
`TwinStrand Biosciences v. Guardant Health
`IPR2022-01400
`
`

`

`Prepared: May 16, 2023
`
`Assistant
`Professor
`
`Associate
`Professor
`
`Associate
`Professor
`
`Marcus Allen
`Hogge Chair in
`Reproductive
`Sciences
`
`Professor
`
`Clinical Instructor Department of
`Obstetrics and
`Gynecology
`Department of
`Obstetrics and
`Gynecology
`Department of
`Obstetrics and
`Gynecology
`Department of
`Obstetrics and
`Gynecology
`Department of
`Obstetrics,
`Gynecology &
`Reproductive
`Sciences
`Department of
`Obstetrics,
`Gynecology &
`Reproductive
`Sciences
`(Primary
`Appointment)
`Department of
`Human Genetics
`Department of
`Pathology
`Department of
`Pathology
`Department of
`Obstetrics and
`Gynecology
`Institute of
`Human Genetics
`UCSF Health
`
`Professor
`
`Professor
`
`Distinguished
`Professor
`Professor
`
`Professor
`
`Professor
`
`PRINCIPAL POSITIONS HELD
`1997 - 2001
`Baylor College of Medicine
`
`2001 - 2006
`
`Baylor College of Medicine
`
`2006 - 2009
`
`Baylor College of Medicine
`
`2009 - 2013
`
`University of Pittsburgh School of
`Medicine
`
`2011 - 2018
`
`University of Pittsburgh School of
`Medicine
`
`2013 - 2018
`
`University of Pittsburgh School of
`Medicine
`
`2013 - 2018
`
`2013 - 2018
`
`University of Pittsburgh, Graduate School
`of Public Health
`University of Pittsburgh School of
`Medicine
`2018 - present University of California, San Francisco
`
`2018 - present University of California, San Francisco
`
`2018 - present University of California, San Francisco
`
`2018 - present Chief Genomic Officer
`
`2 of 68
`
`

`

`Prepared: May 16, 2023
`
`OTHER POSITIONS HELD CONCURRENTLY
`2006 - 2009
`Baylor College of Medicine, Houston,
`TX
`
`2007 - 2009
`
`Baylor College of Medicine, Houston,
`TX
`
`Research
`Director, Womens
`Reproductive
`Health Research
`Director of
`Research
`
`Department of
`Obstetrics and
`Gynecology
`
`2009 - 2018 Magee-Womens Hospital of UPMC Director of
`Reproductive
`Genetics
`
`2009 - 2018 Magee-Womens Hospital of UPMC Co-Director, Fetal
`Diagnostic Center
`
`Department of
`Obstetrics and
`Gynecology
`Department of
`Obstetrics,
`Gynecology &
`Reproductive
`Sciences
`Department of
`Obstetrics,
`Gynecology &
`Reproductive
`Sciences
`Program Director Residency/Fellowship
`in Medical Genetics
`Department of
`Obstetrics,
`Gynecology &
`Reproductive
`Sciences
`Department of
`Obstetrics,
`Gynecology &
`Reproductive
`Sciences
`Department of
`Pathology
`Department of
`Obstetrics and
`Gynecology
`Institute of Human
`Genetics
`UCSF Health
`
`2012 - 2018
`
`University of Pittsburgh School of
`Medicine
`2013 - 2018 Magee-Womens Hospital of UPMC Medical Director,
`Pittsburgh
`Genomics
`Laboratory
`
`2012 - 2018 Magee-Womens Hospital of UPMC Medical Director,
`Pregnancy
`Screening Lab
`
`2018 - present University of California, San
`Francisco
`2018 - present University of California, San
`Francisco
`
`2018 - present University of California, San
`Francisco
`2018 - present University of California, San
`Francisco
`
`HONORS AND AWARDS
`1985
`Phi Beta Kappa Society
`
`3 of 68
`
`Distinguished
`Professor
`Professor
`
`Professor
`
`Chief Genomic
`Officer
`
`Honor Society
`
`

`

`1985
`
`1997
`
`1997
`
`2013
`
`2013
`
`2016
`
`2018
`
`2019
`
`2020
`
`2020
`
`American Chemical Society Award for
`Outstanding Achievement in Chemistry
`First Place Award, Research Day,
`Cleveland Society of Obstetrics and
`Gynecology
`Peter Adam Research Award
`
`Marcus Allen Hogge Chair in
`Reproductive Sciences, University of
`Pittsburgh
`Elected to American Society for Clinical
`Investigation
`Keynote Speaker, International
`Federation of Fertility Societies.
`Elected to Association of American
`Physicians
`Stuart Lindsay Distinguished Professor
`in Experimental Pathology
`Elected to American Gynecological and
`Obstetrical Society
`Elected to the National Academy of
`Medicine
`
`Prepared: May 16, 2023
`
`American Chemical Society
`
`Cleveland Society of Obstetrics and
`Gynecology
`
`Metrohealth Medical Center,
`Cleveland, Ohio
`Endowed Chair
`
`American Society for Clinical
`Investigation
`International Federation of Fertility
`Societies.
`Association of American Physicians
`
`University of California, San Francisco
`
`American Gynecological and
`Obstetrical Society
`National Academy of Medicine
`
`KEYWORDS/AREAS OF INTEREST
`Reproductive Genomics
`Oogenesis
`Ovarian Development
`Germline differentiation
`Uterine leiomyomas
`Population Genomics
`Preventative OMICs
`CLINICAL ACTIVITIES
`CLINICAL ACTIVITIES SUMMARY
`During the COVID-19 pandemic I personally volunteered in helping with vaccinations at
`Mission Hall and City College. Moreover, I also provided on call coverage for our staff at
`vaccination sites when questions arose around clinical scenarios of vaccination
`eligibility/contraindications/adverse side effects.
`
`CLINICAL SERVICES
`2009 - present Prenatal Diagnosis, Genetics and Ultrasound
`2009 - present Adult Genetics
`
`Half a day a week
`Half a day a week
`
`4 of 68
`
`

`

`1999 - 2009
`1999 - 2009
`1999 - 2009
`
`Prenatal Diagnosis, Genetics and Ultrasound
`Labor and Delivery Coverage
`Gynecologic Surgery
`
`Two days a week
`One day a week
`One day a week
`
`Prepared: May 16, 2023
`
`PROFESSIONAL ACTIVITIES
`MEMBERSHIPS
`2020 - present National Academy of Medicine
`2020 - present American Gynecological & Obstetrical Society
`2018 - present Association of American Physicians (AAP)
`2013 - present American Society for Clinical Investigation (ASCI)
`2007 - 2009
`Perinatal Research Society
`2003 - present Society for the Study of Reproduction
`2002 - present American College of Obstetricians and Gynecologists
`2001 - present International Society for Prenatal Diagnosis
`2000 - present Society for Reproductive Investigation
`1999 - present American Society of Human Genetics
`1999 - present American College of Medical Genetics
`
`SERVICE TO PROFESSIONAL ORGANIZATIONS
`2020 - present ACMG Foundation Board of Directors
`2016 - present American College of Obstetricians and Gynecologists
`
`2022 - 2022
`2014 - 2014
`
`National Institute of Health Fellowship Panel
`Society for the Study of Reproduction
`
`2008 - 2010
`
`American College of Obstetricians and Gynecologists
`
`2008 - 2008
`2006 - 2007
`
`Society for the Study of Reproduction
`Society for the Study of Reproduction
`
`5 of 68
`
`
`ACOG Committee
`on Genetics, ASRM
`Liaison
`Invited Reviewer
`Program
`Committee
`Translational
`Research
`ACOG Committee
`on Genetics,
`Member
`Clinical Outreach
`Program
`Committee
`
`

`

`Prepared: May 16, 2023
`
`SERVICE TO PROFESSIONAL PUBLICATIONS
`2009 - present Associate Editor: Journal of Assisted Reproduction and Genetics
`2009 - 2011
`Associate Editor: Endocrine Reviews
`2007 - 2010
`Associate Editor: Molecular and Human Reproduction Associate
`
`2005
`
`2005
`
`2006
`
`INVITED PRESENTATIONS - INTERNATIONAL
`2002
`Maribor Congress on Infertility: "Genetic Regulation of
`Mammalian Oogenesis;" Maribor, Slovenia
`Society for the Study of Reproduction, Annual Meeting:
`"Nobox deficiency and Gene Expression in the Newborn
`Ovary," Quebec City
`Mammalian Oogenesis and Epigenetic Modification
`Workshop: "Transcriptional regulation of early
`Folliculogenesis," Tokyo, Japan
`ESHRE Course on Ovarian Development, ESHRE Annual
`Meeting, "Autosomal gene mutations impairing female
`reproduction, implications from animal models, Lisbon,
`Portugal.
`ESHRE 2008 Conference: "X chromosome genes with a
`role in gametogenesis," Barcelona.
`3rd International Symposium on Reproductive
`Endocrinology and Genetics: "Genetics of Premature
`Ovarian Failure," Hangzhou, Zhejiang Province, China
`Sixth World Congress on Ovulation Induction: "Genetics of
`Folliculogenesis," Naples, Italy.
`1st Congress of TARTEN (Trans-Atlantic Reproductive
`Technologies Network), "Molecular mechanisms behind
`premature ovarian aging," Istanbul, Turkey.
`Invited Speaker at the CHA Medical University International
`Reproductive Symposium, "Genomic Approaches to
`Reproductive Pathology," Seoul, South Korea.
`Canadian Fertility and Andrology Society (CFAS) Annual
`Meeting: "Depletion of the Follicle Reserve" Nova Scotia,
`Canada
`RIMED Symposium: "Reproductive Genomics: "New
`Revelations and Implications for Personalized Medicine"
`Rome, Italy.
`60th Annual Scientific Meeting of Argentine Society for
`Clinical Investigation (SAIC): "Recent Advances of Genomic
`Testing in Perinatal Medicine" Mar del Plata, Argentina.
`
`2008
`
`2010
`
`2010
`
`2011
`
`2011
`
`2015
`
`2015
`
`2015
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`6 of 68
`
`

`

`2015
`
`2016
`
`2016
`
`2016
`
`2016
`
`2017
`
`2018
`
`2019
`2020
`
`2021
`2021
`
`2021
`
`2022
`
`2023
`
`2023
`
`Prepared: May 16, 2023
`
`IFFS/JSRM International Meeting 2015: "What have we
`learned from animal models?" Yokohama, Japan.
`Society for Reproductive Investigation Ovarian Biology
`Meeting: Ovarian Ageing: Epidemiologic, Genetics and
`Metabolic Determinants: "Genetics of Ovarian Failure"
`Montreal, Canada.
`Society for Reproductive Investigation Annual Meeting:
`"Premature Ovarian Failure: Whole Exome Sequencing
`Approaches to Identify Genetic Causes", Montreal, Canada.
`Invited Speaker at Shangdong University; Conference on
`Reproductive Medicine: "Genesis of Leiomyomas"
`Shanghai, China.
`22nd IFFS World Congress: "Diagnostic Advances in
`Reproductive Medicine through Genomics" India Expo Mart
`in New Delhi, India.
`4th World Congress of Reproductive Biology 2017. "Oocyte
`Differentiation During Embryogenesis is Independent of
`Meiosis and Driven by Interplay of Multiple Transcriptional
`Regulators"; Okinawa Convention Center, Okinawa, Japan
`ICE-SEMDSA December 2018, Cape Town, South Africa,
`"Animal Models of Premature Ovarian Failure".
`International IVIRMA Congress
`Chinese Association of Reproductive Medicine/International
`Federation of Fertility Societies
`The Festival of Genomics and Biodata
`NIH KOMP virtual workshop on Combining mouse
`embryonic phenotyping and human sequencing to better
`understand gene essentiality and improve fetal precision
`medicine
`Virtual Presentation "ACMG Practice Resource for
`Screening of AR and X-linked Conditions," National
`University Health System, Singapore.
`International Federation of Fertility Societies (IFFS), Trilogy
`Symposium Lecture
`Best of ESHRE & ASRM (A joint meeting of the European
`Society of Human Reproduction and the American Society
`of Reproductive Medicine). "Unexplained RPL: Lethal
`Genes and Big Data," Orlando, Florida
`14th International Congress of Human Genetics, Cape
`Town, South Africa
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`Invited Speaker
`
`Invited Speaker
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`7 of 68
`
`

`

`Prepared: May 16, 2023
`
`2023
`
`2023
`
`
`
`10th International IVIRMA Congress: Reproductive
`Medicine and Beyond. "Premature Ovarian Insufficiency:
`What is New?" Malaga, Spain
`International Federation of Fertility Societies (IFFS) World
`Congress, Athens, Greece
`
`
`Invited Speaker
`
`Invited Speaker
`
`
`
`2002
`
`2002
`
`2002
`
`2002
`
`INVITED PRESENTATIONS - NATIONAL
`2000
`AAAS 2000 Annual Meeting: "Homocysteine and
`Reproductive Pathology" as part of the Symposia on "New
`Knowledge on Homocyst(e)ine," Washington, D.C.
`Invited Speaker, Grand Rounds, Dept of Obstetrics and
`Gynecology, BCM: "Stem cells and implications for therapy.
`Houston, TX.
`Invited Speaker at the Texas Forum for Female
`Reproduction, 8th Annual Meeting, Houston, TX,
`"Identification of oocyte-specific transcription factors by in
`silico subtraction"
`Invited Speaker at the Postgraduate Courses, American
`Society for Reproductive Medicine Annual Meeting, Seattle,
`WA. Talks presented were entitled: "Functional Genomics
`and Reproductive Pathology", "Genes Leading to Ovarian
`Dysfunction in Women and Mice", "Genes Causing
`Testicular Failure and Azoospermia/Oligospermia."
`Invited Speaker "Lack of Nobox, an oocyte-specific
`homeobox gene, disrupts early Folliculogenesis," Gordon
`Research Conference, Mammalian Gametogenesis &
`Embryogenesis, June 30 - July 5, 2002, Connecticut
`College, New London, CT.
`Invited Speaker, Department of Obstetrics and Gynecology,
`Baylor College of Medicine: "Human Genome Project and
`Reproductive Pathology," June 2003.
`Invited Speaker to Reproductive Health Sciences Branch,
`NIH; Bethesda, MD: "Identification and functional
`characterization of oocyte-specific transcription factors".
`Plenary Session Speaker at the 50th Society for
`Gynecologic Investigation Meeting: "Transcriptional
`regulation of early Folliculogenesis," Washington, D.C.
`Speaker at the Womens Health in The 21st Century
`Symposium: "Meeting Primary Care Needs Through
`Increasing Practice Skills," talk entitled, "The Future of
`Gene Therapy," Houston, TX.
`
`2002
`
`2003
`
`2003
`
`2003
`
`8 of 68
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`

`

`2003
`
`2003
`
`2004
`
`2004
`
`2004
`
`2004
`
`2005
`
`2005
`
`2006
`
`2006
`
`2006
`
`2006
`
`2007
`
`Prepared: May 16, 2023
`
`Invited Speaker at Metrohealth Medical Center, Case
`Western Reserve University: Obstetrics and Gynecology
`Grand Rounds, Cleveland, Ohio: "Functional Genomics and
`Womens Health"
`Invited Speaker at Metrohealth Medical Center, Case
`Western Reserve University, Obstetrics and Gynecology
`Research Seminar, Cleveland, Ohio: "Genetics of Early
`Folliculogenesis"
`Grand Rounds, Dept of Obstetrics and Gynecology, BCM,
`"Markers of Ovarian Cancer"
`Invited Speaker at Northwestern Medical School,
`Department of Obstetrics and Gynecology, Grand Rounds,
`Chicago, Illinois: "Transcriptional Control of Early
`Folliculogenesis.
`Society for Gynecologic Investigation, 51st Meeting;
`Houston, TX: "Nohlh is a helix-loop-helix, oocyte specific
`transcription factor, critical in mammalian gametogenesis"
`Invited Speaker at the Gordon Research Conference on
`Reproductive Tract Biology: "Oocyte-specific transcription
`factors and regulation of Folliculogenesis"
`Invited Speaker at the Reproductive Scientist Development
`Program Meeting: "Masters and Slaves in Oogenesis", Los
`Angeles.
`Grand Rounds, Dept of Obstetrics and Gynecology, BCM:
`"Stem Cells in Reproductive Biology"
`Organizer and Invited Speaker at the Reproductive Scientist
`Developmental Program Meeting, Santa Fe, New Mexico;
`"Ovarian Biology"
`Invited Speaker, Mary C. Martin Lecture, University of
`California, San Francisco: "Regulators in oogenesis and
`spermatogenesis".
`Invited Speaker at the Gene Therapy Seminar Series,
`Baylor College of Medicine, Houston, TX. "Gene Therapy
`and Womens Health, is there anything on the horizon".
`Invited Speaker at the NIH Reproductive Biology Seminar,
`University of Texas, Houston. "The role of germ cell specific
`regulators in folliculogenesis". November 10, 2006.
`Invited Speaker at the NIH Reproductive Biology Seminar,
`Bethesda, Maryland, "Regulators of Female
`gametogenesis".
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`9 of 68
`
`

`

`2007
`
`2008
`
`2008
`
`2009
`
`2009
`
`2009
`
`2010
`
`2010
`
`2011
`
`2011
`
`2011
`
`2012
`
`Prepared: May 16, 2023
`
`Invited Speaker at the Society for the Study of Reproduction
`40th Annual Meeting: "From Oocyte to Embryo," San
`Antonio, TX.
`Invited Speaker at the Society for Gynecological
`Investigation: "Frontiers in oocyte and early embryo
`development," San Diego, 2008.
`Invited Speaker at the PREGER Course, "The role of
`Gametes in Preimplantation Embryo Biology," Philadelphia,
`2008.
`Invited Speaker at the Human Genetics Seminar, Emory
`University, Dept of Human Genetics, Atlanta, GA. "Oocyte
`regulators in development and disease".
`Invited Speaker at the Endocrinology National Meeting:
`"Novel Directions in Premature Ovarian Failure,"
`Washington, DC.
`Invited Speaker at the Reproductive Biology Seminar
`Series, UT Southwestern, Dallas: "Oocyte regulators in
`development and disease".
`Grand Rounds Department of Obstetrics and Gynecology,
`Magee-Womens Hospital, UPMC: "Array CCGH in
`Obstetrics and Gynecology".
`Invited Speaker at the D.C. Johnson Seminar Series,
`Center for Reproductive Sciences, "Genetics of Premature
`Ovarian Failure," KU Medical Center, Kansas City, KS.
`Invited Speaker at the Society for Maternal-Fetal Medicine
`and American Association of Obstetricians and
`Gynecologist Foundation Annual Scholars' Retreat,
`"Oogenesis and Ovarian Failure," Magee-Womens
`Research Institute and Foundation, Pittsburgh, PA
`Invited Speaker at the RSDP conference, "Career Paths for
`Physician Scientists", Boulder, Colorado.
`Invited Speaker at the 9th Annual Women and Infants
`Health Care Conference: "Current State of the Art in
`Genetic Consultation and Diagnosis from Pre-Conception to
`Birth," Magee-Womens Hospital of UPMC, Pittsburgh, PA.
`Invited Speaker at the 45th Annual Meeting of the Society
`for the Study of Reproduction: "Molecular Mechanisms and
`Consequences of Premature Ovarian Aging," The Penn
`State University, State College, PA
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`10 of 68
`
`

`

`2012
`
`2012
`
`2012
`
`2013
`
`2013
`
`2014
`
`2014
`
`2014
`
`2014
`
`2014
`
`2014
`
`2014
`
`Prepared: May 16, 2023
`
`Invited Speaker at the Magee-Womens Hospital of UPMC
`Board of Directors and V.P. Meeting: "The Future of
`Genetic Testing," Magee-Womens Hospital of UPMC,
`Pittsburgh, PA
`Invited Speaker at the NIH/NICHD & American Society for
`Reproductive Medicine Conference on Ovarian Reserve:
`Regulation and Implications for Womens Health: "The
`State-of-the Science in the Identification of Genetic Markers
`for Premature Ovarian Insufficiency." San Diego, CA.
`Invited Speaker at the Center for Reproductive Biology and
`Health: "Molecular Determinants of Reproductive Life
`Span", Pennsylvania State University, State College, PA.
`Invited Speaker at Lectures in Reproductive Science (LRS)
`Seminar Series: "Primordial Follicle Activation,"
`Northwestern University, Evanston, IL.
`Provost's Inaugural Lecture, Marcus Allen Hogge Chair in
`Reproductive Sciences, University of Pittsburgh: "Ex Ovo
`Omnia", Pittsburgh, PA.
`Molecular Medicine Research Seminar, Children's Hospital
`of Pittsburgh: "Molecular Mechanisms Behind Premature
`Ovarian Aging." Lawrenceville, PA
`Invited Speaker at Oregon Health & Science University,
`Oregon National Primate Research Center, Division of
`Reproductive and Developmental Seminar Series:
`"Molecular Mechanisms Behind Premature Ovarian Aging,"
`Portland, Oregon
`Invited Speaker at the University of Pittsburgh Annual
`Celebration of Science, Science 2014 - Sustain It!: "Stem
`Cells Remixed," Pittsburgh, PA; October 3, 2014
`Invited Speaker at American Society for Reproductive
`Medicine, "Gamete Reserve II - Ovary", Honolulu, HI
`Invited Speaker at OvaScience Symposium "Ovarian
`Follicles: From Basic Science to Clinical Application", Palo
`Alto, CA
`Invited Speaker at the Center for Research on
`Reproduction and Womens Health, "Molecular Mechanisms
`Behind Premature Ovarian Aging", Perelman School of
`Medicine at the University of Pennsylvania, Philadelphia,
`PA
`Invited Speaker at Grand Rounds, Department of Obstetrics
`and Gynecology, Magee-Womens Hospital, UPMC:
`"Update on Prenatal Aneuploidy Detection," Pittsburgh, PA.
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`11 of 68
`
`

`

`2015
`
`2015
`
`2015
`
`2015
`
`2015
`
`2015
`
`2015
`
`2015
`
`2015
`
`2016
`
`2016
`
`2016
`
`Prepared: May 16, 2023
`
`Invited Speaker at the Center for Fertility and Reproductive
`Endocrinology at Magee-Womens Hospital, UPMC, IVF
`Retreat: Preimplantation Genetic Screening," Pittsburgh,
`PA; January 12, 2015
`Invited Speaker at the Premalignant Working Group
`Research Symposium at Magee-Womens Hospital, UPMC:
`"Med 12 Associated Reproductive Pathologies" Pittsburgh,
`PA.
`Invited Speaker at the Florida International University,
`Herbert Wertheim College of Medicine Research Seminar
`Series: "Molecular Mechanism Behind Premature Ovarian
`Aging" Miami, FL
`Invited Speaker at the Society for Reproductive
`Investigation 62nd Annual Scientific Meeting: "Exomes,
`Chromosomes and Ovarian Failure" San Francisco, CA.
`Invited Speaker at Grand Rounds, the Center for Human
`Reproduction: "Genomic Markers of Ovarian Reserve" New
`York, New York; May 12, 2015.
`Invited Speaker at the MCCBP Work In Progress Seminar
`Fall 2015 "Exome Sequencing, Gonadal Failure and
`Genomic Instability" University of Pittsburgh Cancer
`Institute, Pittsburgh, PA
`Invited Speaker at the RSDP 2015 Scholar Retreat:
`"Mediator Complex Subunit 12 (Med12) Exon 2 Missense
`Mutation Causes Uterine Leiomyomas and Genomic
`Instability" Boulder, Colorado; September 12, 2015.
`Invited Speaker at the P50 Outreach Seminar: "Genomic
`Approaches to Gonadal Failure" Weill Cornell Medical
`College, New York, New York.
`Invited Speaker at the RIMED Symposium: "Reproductive
`Genomics: "New Revelations and Implications for
`Personalized Medicine" Rome, Italy.
`Invited Speaker at Grand Rounds, Department of Obstetrics
`Gynecology, UPMC Mercy Hospital: "Preimplantation
`Genetic Testing: Are We Ready For Whole Genome
`Sequencing," Pittsburgh, PA.
`Speaker for the 2016 P01 Seminar Series at Northwestern
`University Department of Obstetrics and Gynecology,
`"MED12 Functions in Reproductive Pathology" Chicago, IL.
`Invited Speaker at UPMC Hamot Research Days 2016
`Genetics and Genomics in Medicine: "Controversies
`Surrounding Prenatal Genetic Screening" Erie, PA
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`12 of 68
`
`

`

`2016
`
`2016
`
`2016
`
`2016
`
`2016
`
`2016
`
`2016
`
`2017
`
`2018
`
`2018
`
`2018
`
`2018
`2018
`2018
`2018
`
`2018
`
`Prepared: May 16, 2023
`
`Invited Speaker at the 2016 Annual Meeting of the Society
`for the Study of Reproduction: "Med12 and Reproductive
`Pathology" San Diego, California.
`Invited Speaker at the 2016 Gordon Research Conference
`Mammalian Reproduction: "Reproductive Aging and Overall
`Health: Is There a Link?" Waterville, New Hampshire;
`august 21-26, 2016.
`Invited Speaker at the 5th Annual Sanford Imagenetics
`Genomic Medicine Symposium: "Genomic Approaches to
`Reproductive Medicine" Sanford Center - Sioux Falls, SD
`22nd IFFS World Congress: "Diagnostic Advances in
`Reproductive Medicine through Genomics" India Expo Mart
`in New Delhi, India.
`Magee-Womens Research Institute 2016 Annual Retreat:
`"Genetics of Early Folliculogenesis"; Pittsburgh, PA
`Translational Reproductive Biology and Clinical
`Reproductive Endocrinology Conference: "Genetic Control
`of Follicle Recruitment"; New York, New York; November
`19, 2016.
`Womens Cancer Research Center Work-In-Progress
`Seminar: "Genetic Underpinnings of Leiomyoma";
`Pittsburgh, PA
`Magee-Womens Research Institute Work-in-Progress
`Conference and Research Seminar Series. "Reproductive
`Aging and Overall Health"; Magee-Womens Research
`Institute, Pittsburgh, PA.
`Augusta University Grand Rounds: Diagnostic Advances in
`Reproductive Medicine through Genomics
`Diagnostic Advances in Reproductive Medicine Through
`Genomics Baylor Health Care Systems, Dallas TX -
`September 2018.
`Committee on Genetics ACOG, Washington DC October
`2018.
`Magee Women's Research Summit October 2018.
`NICHD Strategic Planning, October 2018.
`ASHG San Diego, CA October 2018
`Grand Rounds and Reproductive Seminar, University of
`Colorado, Denver, CO,
`University of Nevada, Reno, NV, Reproductive Aging
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`Invited Speaker
`Invited Speaker
`Invited Speaker
`
`Invited Speaker
`
`13 of 68
`
`

`

`2019
`2019
`
`2019
`
`2019
`2019
`2019
`
`2019
`2019
`
`2020
`
`2020
`2021
`
`2021
`
`2021
`
`2021
`
`2021
`
`2022
`
`2022
`2022
`
`Prepared: May 16, 2023
`
`Precision Medicine World Conference, January 2019
`Buck Institute, Novato California, Developmental Origins of
`Reproductive Aging
`Illumina Symposium on Complex and Mendelian Disease
`Research Symposium
`ASRM Genetics of Premature Ovarian Aging
`AMA, Chicago. Precision Medicine Roundtable
`ASRM Preimplantation Genetic Screening for aneuploidy
`and beyond: FISH, microarrays, qRT-PCR, next gene
`sequencing, and SOMA
`ASHG Genetics of Premature Ovarian Insufficiency
`UC Santa Cruz Seminar Series:Clinical Genetics and
`Genomics at UCSF
`Precision Medicine World Congress, Unique Populations
`Study Collaborations
`Precision Medicine World Congress, Women's Health
`ASRM Postgraduate Course, “Reproductive Aging: Meeting
`the Challenges in Clinical and Laboratory Practice”
`NICHD/ASRM Workshop: "Artificial Intelligence/Machine
`Learning to Develop Personalized Approaches to Improve
`Reproductive Health Outcomes"
`ENDO (Endocrine Society, Virtual Meeting), Developmental
`Origins of Reproductive Aging
`Bohan Visiting Professor Lecture, University of Kansas
`Medical Center, Kansas City, Kansas
`AHA Webinar: 3D Health Initiative and Precision Medicine
`Efforts at UCSF
`ASHG Genetics of Lethal Genes and their implication for
`carrier screening and pregnancy loss
`SSR Ovarian Workshop, Spokane, Washington
`European and American Society of Reproductive Medicine
`Conference
`
`Invited Speaker
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`Invited Speaker
`Invited Speaker
`
`Invited Speaker
`Invited Speaker
`
`Chair
`
`Chair
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`Invited Speaker
`
`INVITED PRESENTATIONS - REGIONAL AND OTHER INVITED PRESENTATIONS
`2010
`Grand Rounds Department of Obstetrics and Gynecology,
`Invited Speaker
`Magee-Womens Hospital, UPMC: "Array CCGH in
`Obstetrics and Gynecology".
`
`14 of 68
`
`

`

`2011
`
`2011
`
`2012
`
`2013
`
`2014
`
`2015
`
`2015
`
`2015
`
`2016
`
`2016
`
`2016
`
`Prepared: May 16, 2023
`
`Invited Speaker at the Society for Maternal-Fetal Medicine
`and American Association of Obstetricians and
`Gynecologist Foundation Annual Scholars' Retreat,
`"Oogenesis and Ovarian Failure," Magee-Womens
`Research Institute and Foundation, Pittsburgh, PA
`Invited Speaker at the 9th Annual Women and Infants
`Health Care Conference: "Current State of the Art in
`Genetic Consultation and Diagnosis from Pre-Conception to
`Birth," Magee-Womens Hospital of UPMC, Pittsburgh, PA.
`Invited Speaker at the Magee-Womens Hospital of UPMC
`Board of Directors and V.P. Meeting: "The Future of
`Genetic Testing," Magee-Womens Hospital of UPMC,
`Pittsburgh, PA
`Provost's Inaugural Lecture, Marcus Allen Hogge Chair in
`Reproductive Sciences, University of Pittsburgh: "Ex Ovo
`Omnia", Pittsburgh, PA.
`Invited Speaker at Grand Rounds, Department of Obstetrics
`and Gynecology, Magee-Womens Hospital, UPMC:
`"Update on Prenatal Aneuploidy Detection," Pittsburgh, PA.
`Invited Speaker at the Center for Fertility and Reproductive
`Endocrinology at Magee-Womens Hospital, UPMC, IVF
`Retreat: Preimplantation Genetic Screening," Pittsburgh,
`PA; January 12, 2015
`Invited Speaker at the Premalignant Working Group
`Research Symposium at Magee-Womens Hospital, UPMC:
`"Med 12 Associated Reproductive Pathologies" Pittsburgh,
`PA.
`Invited Speaker at the MCCBP Work In Progress Seminar
`Fall 2015 "Exome Sequencing, Gonadal Failure and
`Genomic Instability" University of Pittsburgh Cancer
`Institute, Pittsburgh, PA
`Invited Speaker at Grand Rounds, Department of Obstetrics
`Gynecology, UPMC Mercy Hospital: "Preimplantation
`Genetic Testing: Are We Ready For Whole Genome
`Sequencing," Pittsburgh, PA.
`Invited Speaker at Grand Rounds, Department of Obstetrics
`Gynecology, UPMC Mercy Hospital: "Preimplantation
`Genetic Testing: Are We Ready For Whole Genome
`Sequencing," Pittsburgh, PA.
`Invited Speaker at the Magee-Womens Research Institute
`2016 Annual Retreat: "Genetics of Early Folliculogenesis";
`Pittsburgh, PA
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`15 of 68
`
`

`

`Prepared: May 16, 2023
`
`2016
`
`2017
`
`
`2022
`
`2022
`
`2023
`
`2023
`
`Invited Speaker at the Womens Cancer Research Center
`Work-In-Progress Seminar: "Genetic Underpinnings of
`Leiomyoma"; Pittsburgh, PA
`Invited Speaker at the Magee-Womens Research Institute
`Work-in-Progress Conference and Research Seminar
`Series. "Reproductive Aging and Overall Health"; Magee-
`Womens Research Institute, Pittsburgh, PA.
`
`Invited Speaker and Session Chair at the Precision
`Medicine World Conference. "Introduction to Women's
`Health," Silicon Valley, San Jose
`Invited Speaker at the Federation of American Societies of
`Experimental Biology Conference. "Developmental Origins
`of Ovarian Aging and Infertility." Palm Springs, CA
`Invited Speaker at the 7th Annual UCSF Health
`Improvement Symposium. "Clinical PGx Program,"
`University of California at San Francisco
`Invited Speaker at the Precision Medicine World
`Conference. "Clinical Pharmacogenetics Implementation at
`UCSF Health," Silicon Valley, San Jose
`
`Invited Speaker
`
`Invited Speaker
`
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`Invited Speaker
`
`CONTINUING EDUCATION AND PROFESSIONAL DEVELOPMENT ACTIVITIES
`2011
`Leadership Development for Physicians in Academic Health Centers, Harvard
`School of Public Health
`Anatomic Pathology and Laboratory Medicine Grand Rounds (MGR 22003)
`
`2022
`
`GOVERNMENT AND OTHER PROFESSIONAL SERVICE
`2009 - present NIH Special Emphasis Panels
`2008 - 2012
`NIH CMIR Study Section, Bethesda, MD
`2011 - 2011
`NIH/NICHD VISION Workshop on Pregnancy and
`Pregnancy Outcomes, Bethesda, MD.
`NIH/NICHD Vision Workshop on Reproduction. Bethesda,
`MD
`NIH Fragile-X Associated Primary Ovarian Insufficiency,
`The Eunice Kennedy Shriver National Institute of Child
`Health and Human, Rockville, MD
`NIH Panel IRAP Review
`NIH Panel Genetics Health and Disease Panel.
`
`2011 - 2011
`
`2014 - 2014
`
`2017 - 2017
`2018 - 2018
`
`16 of 68
`
`Ad hoc Member
`Regular Member
`Panel Member
`
`Panel Member
`
`Panel Member
`
`Panel Member
`Panel Member
`
`

`

`Prepared: May 16, 2023
`
`2018 - 2018
`
`NIH Fragile-X Associated Primary Ovarian Insufficiency
`Meeting, Bethesda, MD
`2018 - present BIOS Advisory Committee
`2018 - present Institute of Human Genetics Task Force
`2019 - present Reproductive Genetics Technology Consortium
`
`Co-chair
`
`Member
`Member
`Member
`
`UNIVERSITY AND PUBLIC SERVICE
`SERVICE ACTIVITIES SUMM