Address:
`
`PROFESSOR STEPHEN GRAHAM DAVIES
`
`New College,
`University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K.
`Tel: 01865-275646
`email: steve.davies@chem.ox.ac.uk
`
`URL:
`
`http://davies.chem.ox.ac.uk/home.aspx
`
`Date of Birth:
`
`24.02.50 (Birmingham, UK) Age: 72
`
`Education:
`
`School:
`
`Berkhamsted 1963 - 1968
`
`University of Oxford B.A. Chemistry 1973
`Thesis entitled "Benzene Oxide and Related Compounds"
`D.Phil. 1975 (Supervisor: Dr G.H. Whitham)
`Thesis entitled "Studies on Epoxides"
`
`University of Paris D.Sc. (Docteur ès Sciences) 1980
`Thesis entitled "Contribution a La Chimie des Epoxydes"
`
`Honorary Degrees:
`
`2013
`
`
`
`Positions Held:
`
`1975 - 1977
`
`
`
`1977 - 1978
`
`1978 -1980
`
`1980 -1996
`
`1996 - 2004
`
`2004 - 2006
`
`2006 - 2020
`
`2006- 2011
`
`Doctor Honoris Causa, University of Salamanca, Spain
`(The University of Salamanca is one of the oldest in the world and only
`awards three “Doctor Honoris Causa” per annum)
`
`I.C.I. Postdoctoral Fellow,Dept. of Inorganic Chemistry, Oxford.
`(Professor M.L.H. Green, FRS)
`
`N.A.T.O. Postdoctoral Fellow, I.C.S.N., C.N.R.S., Gif-sur-Yvette,
`Paris. (Professor Sir Derek Barton, FRS)
`
`Attache de Recherche, C.N.R.S., I.C.S.N., C.N.R.S., Gif-sur-Yvette, Paris
`
`Lecturer in Organic Chemistry, Dyson Perrins Laboratory, Oxford.
`Fellow of New College, Oxford
`
`Professor of Chemistry, Dyson Perrins Laboratory, Oxford
`Fellow of New College, Oxford
`
`Professor of Chemistry, Chemistry Research Laboratory, Oxford
`Fellow of New College, Oxford
`
`Waynflete Professor of Chemistry, University of Oxford
`Fellow of Magdalen College, Oxford (The Waynflete Chair is the oldest and
`only named chair in Organic Chemistry at Oxford)
`
`Chairman of Chemistry, University of Oxford
`(Full responsibility for all teaching, research, financial and managerial matter
`for one of the largest Chemistry Departments in the world)
`
`Bausch Health Ireland Exhibit 2029, Page 1 of 42
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`
`

`

`2020 -
`
`
`
`Waynflete Professor Emeritus, University of Oxford
`Extraordinary Lecturer, New College, Oxford
`
`
`
`Awards:
`
` 1984: Hickinbottom Fellowship
`1985: Pfizer Award for Chemistry
`1986: Corday Morgan Medal (1984): Royal Society of Chemistry
`1987: Royal Society of Chemistry Award for Organometallic Chemistry
`1988: Pfizer Award for Chemistry
`1989: Royal Society of Chemistry Bader Award
`1996: Tilden Lecture Award, Royal Society of Chemistry
`1997: Royal Society of Chemistry Award in Stereochemistry
`1998: Prize Lectureship of the Society of Synthetic Organic Chemistry, Japan
`2008: Distinguished Technopreneur Award, Singapore
`2011: Royal Society of Chemistry Perkin Prize for Organic Chemistry
`2021: Royal Society London Mullard Award
`
`Publications: 625 publications (h index 64, 18229 cites, October 2022)
`
`
`URL for publications: http://davies.chem.ox.ac.uk/publications.aspx
`
`
`Membership of Committees
`
`Society of the Chemical Industry: Fine Chemicals Committee
`1986 -1992
`Society of the Chemical Industry: Awards and Academic Relations Committee
`1990 -1993
`Royal Society of Chemistry: Perkin Council
`1987 -1990
`SERC - Organic Chemistry Subcommittee
`1988 -1991
`SERC - Clean Technology Directorate
`1991 -1992
`EPSRC Clean Technology Panel
`1991 -1992
`1994 -1995 Academic Secretary, Sub-Faculty of Chemistry.
`1994 -1995
`Physical Sciences Board, Oxford University
`1995 - 2000 Technology Transfer Advisory Group, Oxford University.
`1998 - 2010 Conflict of Interest Committee, Oxford University.
`1997 - 2020 RSC Oxford/Cambridge International Synthesis Meeting Organising Committee
`(Chair 2001, 2005, 2009, 2013 and 2017)
`Intellectual Property Advisory Group, Oxford University
`2000 - 2020
`2002 - 2014 Board of Electors of the Newton Abraham Visiting Professorship
`2006 – 2007 Medical Sciences Divisional Board
`2006 - 2011 MPLS Divisional Board
`2006 - 2011 MPLS General Purposes Committee
`2006 - 2010 Begbroke Science Park Strategy Group
`
`
`
`
`Editorial Appointments
`
`J. Chem. Soc. Perkin Transactions: Editorial Board Member
`1989 - 1992
`"Oxford Chemistry Primers", OUP
`Founding Editor and Editor of Organic Series
`1989 -
`"Oxford Chemistry Masters", OUP
`Founding Editor and Editor of Organic Series
`1995 -
`
`
`
`1990 - 2017 Tetrahedron:
`Executive Editorial Board Member
`1990 - 2017 Tetrahedron: Asymmetry
`
`Founder and Editor in chief
`2005 -
`"On Chemistry" Books
`
`Editor
`
`
`
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`

`

`Companies Founded and Directorships
`
`1992 - 1998 Oxford Asymmetry Limited; Founder and Director
`
`
`(Asymmetric Synthesis)
`
`1995 - 1998 Oxford Diversity Limited; Founder and Research Director
`
`
`(Combinatorial Chemistry)
`
`1998 - 2000 Oxford Asymmetry International plc; Founder and Director
`
`
`(Drug Discovery Services)
`
`2003 - 2004 VASTox Limited; Founder and Non-executive Chairman
`
`
`(Orphan Drug Discovery)
`
`2004 - 2006 VASTox plc; Founder and Non-executive Chairman
`
`
`(Orphan Drug Discovery)
`
`2004 -
`
`
`
`2006 - 2013 Summit Corporation plc (formerly VASTox plc); Founder and Non-executive Director
`
`
`(Pharmaceuticals)
`
`2006 - 2009 Oxray Limited; Founder and Non-executive Director
`
`
`(Crystallography Software Developer)
`
`2011 -
`
`
`
`2011 - 2014 MuOx Ltd. (Acquired by Summit Therapeutics plc); Founder and Non-executive
`Chairman
`(Drug Discovery for Orphan Muscle Diseases)
`
`OxStem Limited; Founder and Non-executive Director
`(Regenerative Medicine via endogeneous control of cell differentiation)
`
`SciInk Limited; Founder and Non-executive Chairman
`(Not for profit Undergraduate text publisher)
`
`
`2014 - 2018
`
`
`
`Summit Therapeutics plc; Non-executive Director
`(2003 London AIM SUMT: 2015 NASDAQ SUMM)
`(Drug Development for Duchenne Muscular Dystrophy and Antibiotic against
`Clostridium difficile)
`
`
`2017 - 2022 Oxstem Neuro Ltd., Oxstem Cardio Ltd., Oxstem Ocular Ltd., Oxstem Oncology Ltd.,
`Oxstem Beta Ltd. and Oxstem Immuno Ltd. (Regenerative Medicine)
`
`
`2021 -
`
`
`Directorships:
`
`2007 - 2009 Oxeco plc; Non-executive Director
`
`
`(IP commercialisation)
`
`2008 - 2021 Oxford University Innovation plc; Non-executive Director
`
`
`(Oxford University’s IP commercialisation company)
`
`2010 - 2011 Scientific Research Capital Limited; Non-executive Chairman
`
`
`(IP commercialisation)
`
`2018 -
`
`
`Raphael Laboratories Ltd.; Founder and Non-executive Director
`(Prophylactics against viral respiratory infections)
`
`Verivin Ltd. Non-executive Director (Non-invasive wine, urine and blood analysis)
`
`Bausch Health Ireland Exhibit 2029, Page 3 of 42
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`

`

`STEPHEN G. DAVIES – PUBLICATIONS LIST
`
`trans-Cycloalkenes. Part IV. Some aspects of the chemistry of trans-cyclo-octene
`K. T. Burgoine, S. G. Davies, M. J. Peagram and G. H. Whitham, J. Chem. Soc., Perkin Trans. 1, 1974, 2629
`
`Carbon-13 nuclear magnetic resonance spectra of some epoxides
`S. G. Davies, G. H. Whitham, J. Chem. Soc., Perkin Trans. 2, 1975, 861
`
`A convenient synthesis of β,γ-unsaturated carboxylic acids and esters. The isomeric 5-t-butylcyclohex-2-enecarboxylic
`acids
`S. G. Davies, G. H. Whitham, J. Chem. Soc., Perkin Trans. 1, 1976, 2279
`
`Inorgano-Grignard Reagents: Preparation, Reactions and X-ray Crystal Structure of Bis-(η-cyclopentadienyl)-
`hydridomolybdenum[bromo(bis-tetrahydrofuran)magnesium]
`S. G. Davies, M. L. H. Green, K. Prout, A. Coda and V. Tazzoli, Chem. Commun., 1977, 135
`
`Stereoselectivity in the Epoxidation of βγ-Unsaturated Carboxylic Acids
`S. G. Davies, G. H. Whitham, J. Chem. Soc., Perkin Trans. 1, 1977, 572
`
`Benzene Oxide-Oxepin. Oxidation to Muconaldehyde
`S. G. Davies, G. H. Whitham, J. Chem. Soc., Perkin Trans. 1, 1977, 1346
`
`trans-Cycloalkenes Part 7. Variable Temperature 13C Nuclear Magnetic Resonance Studies on cis,trans-Cyclo-
`octa-1,5-diene and Related Compounds
`S. G. Davies, P. F. Newton, G. H. Whitham, J. Chem. Soc., Perkin Trans. 2, 1977, 1371
`
`Rules for Predicting the Regioselectivity of Nucleophilic Attack on 18-Electron Organotransition Metal Cations
`Containing Polyene Ligands
`S. G. Davies, M. L. H. Green, D. M. P. Mingos, Nouveau Journal de Chimie, 1977, 1, 445
`
`Photoinduced Synthesis of Binuclear Molybdenocene and Tungstenocene Derivatives: Catalytic Deoxygenation of
`Epoxides by Metallocenes
`M. Berry, S. G. Davies, M. L. H. Green, J. Chem. Soc., Chem. Commun., 1978, 99
`
`Nucleophilic addition to organotransition metal cations containing unsaturated hydrocarbon ligands: a survey and
`interpretation
`S. G. Davies, M. L. H. Green, D. M. P. Mingos, Tetrahedron, 1978, 34, 3047
`
`Inorgano-Grignard Reagents. Preparations and Reactions of [Bromobis(tetrahydrofuran)-magnesio]bis(η-
`cyclopentadienyl)-hydridomolybdenum.
`S. G. Davies, M. L. H. Green, J. Chem. Soc., Dalton, 1978, 1510
`
`Indane 3a,4-Oxide: Formation by Isomerisation of Indane-3a,7a-Oxide and Confirmation of Structure by an
`Alternative Synthesis.
`S. G. Davies, G. H. Whitham, J. Chem. Soc., Perkin Trans. 1, 1978, 1479
`
`Chromium Hexacarbonyl Isomerisation of Ergosterol and Related Dienes
`D. H. R. Barton, S. G. Davies, W. B. Motherwell, Synthesis, 1979, 265
`
`Stepwise Oxidative Decarbonylations of Organometallic Cations of Iron.
`S. G. Davies, J. Organometal. Chem., 1979, 179, C5
`
`Thermally Induced Formation of Neoergosteryl Benzoate and Ergosta-8(14)-22-dienyl Benzoate from Ergosteryl
`Benzoate Iron Tricarbonyl.
`A. F. Mateos, S. G. Davies, Anales de Quimica, 1979, 75, 385
`Hydride Reduction of the Cation [(η5-C5H5)Fe(triphos)] PF6 : Direct Nucleophilic Attack on the Metal and
`Hydrogen Exchange in the Product Hydride (η5-C5H5)FeH-(triphos). (triphos = Ph2PCH2CH2PPhCH2CH2PPH2)
`S. G. Davies, H. Felkin, O. Watts. Chem. Commun., 1980, 159
`Chemistry of (η5-C5H5)Ru(Ph2PCH2CH2PPh2)Cl: Preparation of Cationic Ruthenium Olefin Complexes.
`S. G. Davies, F. Scott, J. Organometal. Chem., 1980, 188, C41
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`Synthesis of 10 (S)-Methyl-Codeine and 10 (S)-Methyl-Morphine
`H. B. Arzeno, D. H. R. Barton, S. G. Davies, X. Lusinchi, B. Meunier, C. Pascard, Nouveau J. Chimie, 1980, 4, 369
`
`Synthesis and Reactions of Alkyl- and Aryl-substituted Metallacyclobutane Derivatives of Molybdenum and Tungsten
`G. A. Adam, S. G. Davies, M. Ephritikine, K. A. Ford, M. L. H. Green, P. F. Todd, J. Molecular Catal., 1980, 8, 15
`
`Epoxide Opening with Organocuprates and Grignard Reagents in the Presence of Chiral Ligands
`S. G. Davies, S. Wollowitz, Tetrahedron Lett., 1980, 21, 4175
`Hydride Reduction of the Cations {(η5-C5H5)Fe[(Ph2PCH2)3CMe]}PF6,{(η5-C5H5)Ru[(Ph2PCH2CH2)2-
`PPh]}PF6 and {(η5-C5H5)Ru[(Ph2PCH2)3CMe]} PF6: Regioselectivity and Mechanism
`S. G. Davies, H. Felkin, T. Fillebeen-Khan, F. Tadj, O. Watts, Chem. Commun., 1981, 341
`
`Stereochemical and Mechanistic Aspects of the Nickel Complex Catalysed Formation of Olefins from Allylic
`Alcohols and Grignard Reagents.
`H. Felkin, M. Joly-Goudket, S. G. Davies, Tetrahedron Lett., 1981, 22, 1157
`Reactivity of the Inorgano-Grignard (η5-C5H5)(Ph2PCH2CH2PPh2)FeMgBr Towards Halogenogermanes.
`N. Aktogu, S. G. Davies, J. Dubac, P. Mazerolles, J. Organomet. Chem., 1981, 212, C13
`
`Asymmetric Synthesis in the Nickel Complex Catalysed Formation of Olefins from Allyl Alcohols and Grignard
`Reagents.
`M. Cherest, H. Felkin J. D. Umpleby, S. G. Davies, Chem. Commun., 1981, 681
`
`Intramolecular General Acid Catalysis in the Binding Reactions of α2-Macroglobulin and Complement Components C3
`and C4
`S. G. Davies, R. B. Sim, Bioscience Reports, 1981, 1, 461
`
`2-Substituted Bicyclo[3. 1.0]hexanes: Determination of Stereochemistry.
`S. G. Davies, J. Chem. Res. S., 1982, 197
`
`Hydride reduction of the cation [(η5-C5H5)Fe(Ph2PCH2CH2PPh2)CO]PF6; formation of
`(η5-C5H5)FeH(CO)(Ph2PCH2CH2PPh2) and elimination of H2 from [(η5-C5H5)FeH(CO)]2(Ph2PCH2CH2PPh2)
`S. G. Davies, J. Hibberd, S. J. Simpson, O. Watts J. Organomet. Chem., 1982, 238, C7
`
`Organotransition Metal Chemistry: Applications to Organic Synthesis.
`S. G. Davies, Pergamon Press, Nov. 1982, 1
`Preparation and Reactivity of the Anion [(η5-C5H5)Fe(CO)(PPh3)(COCH2)]Li.
`N. Aktogu H. Felkin, S. G. Davies, Chem. Commun., 1982, 1303
`Evidence for the Iron Formyl (η5-C5H5)Fe(Ph2PCH2CH2PPh2)(CHO).
`S. G. Davies, S. J. Simpson, J. Organomet. Chem., 1982, 240, C48
`Disproportionation of the Iron Carbonyl Hydride (η5-C5H5)Fe(CO)H(Ph2PCH2CH2PPh2) to the Iron Methyl (η5-
`C5H5)Fe(Ph2PCH2CH2PPh2)Me
`S. G. Davies, J. Hibberd, S. J. Simpson, Chem. Commun., 1982, 1404
`Hydride Reduction of the Cation [(η5-C5H5)Fe(Ph2PCH2CH2PPh2)CO]PF6; Formation of (η5-C5H5)-FeH(CO)
`(Ph2PCH2CH2PPh2) and Elimination of H2 from [(η5-C5H5)FeH(CO)]2(Ph2PCh2CH2PPh2)
`S. G. Davies, J. Hibberd, S. J. Simpson, O. Watts, J. Organomet. Chem., 1983, 241, C31
`Fragmentation of (η5-C5H5)Fe(CO)(PPh3)(COCH2COR) Complexes to the Cation [(η5-C5H5)Fe(CO)2-(PPh3)]+
`S. G. Davies, O. Watts, N. Aktogu, H. Felkin, J. Organometal. Chem., 1983, 243, C51
`Regioselectivity of Hydride Addition to [(η5-C5H5)Fe(Ph2PCH2CH2PPh2) CO]PF6 and Rearrangement of (η5-
`C5H5)Fe(Ph2PCH2CH2PPh2)(CO)H to (η4-C5H6)Fe(Ph2PCH2CH2PPh2)CO
`S. G. Davies, J. Hibberd, S. J. Simpson, J. Organometal. Chem., 1983, 246, C16
`Electron-rich Cations: Preparation and Hydride Reductions of the Cations [Fe(η5-C5H5)- [PhP(CH2CH2PPh2)2]]+,
`[Fe(η5-C5H5)[MeC(CH2PPh2)3]]+ and [Fe(η5-C5H5)[C(CH2-PPh2)4]]+
`S. G. Davies, S. J. Simpson, H. Felkin, F. Tadj, O. Watts, J. Chem. Soc., Dalton, 1983, 981
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`Disubstituted Vinylidene Complexes of Iron and Ruthenium: Nucleophilic Properties of η1-Acetylide Ligands.
`S. Abbott, S. G. Davies, P. Warner, J. Organometal. Chem., 1983, 246, C65
`Electron-rich cations: Preparation and Hydride Reductions of the Cations {(η5C5H5)Ru[MeC-(CH2PPh2)3]}+ and
`{(η5-C5H5)Ru[PhP(CH2CH2PPh2)2]}+.
`S. G. Davies, S. J. Simpson, H. Felkin, T. Fillebeen-Khan, Organometallics, 1983, 2, 539
`Stereoselective Elaboration of the Acyl Ligand in (η5-C5H5)Fe(CO) (PPh3)(COCH2R) via the Alkylation of the
`Anions [(η5-C5H5)Fe(CO)(PPh3)(COCHR)]Li (R=Me, Et).
`G. J. Baird, S. G. Davies, J. Organometal. Chem., 1983, 248, Cl
`Stereochemistry of 5-Substituted η4-Cyclopentadiene Transition-metal Complexes
`S. G. Davies, S. D. Moon, S. J. Simpson, S. E. Thomas, J. Chem. Soc., Dalton, 1983, 1805
`Preparation and Hydride Reduction of the Electron-Rich Cations [(Me5C5)Fe(CO)2L]+ (L=CO,PPh3,PMe3) and
`[(Me5C5)Fe(CO)(Ph2PCH2CH2PPh2)]+
`S. G. Davies, S. J. Simpson, S. E. Thomas, J. Organometal. Chem., 1983, 254, C29
`Stereochemical Control and Mechanistic Aspects of the Alkylation of (η5-C5H5)Fe(L)(CO)(COCHR)]-Li+
`(L=PPh3, PPh2NEt2; R=Me, Et): X-Ray Crystal Structure of [(η5-C5H5)Fe(PPh3)(CO){COCH(Me)Et}].
`G. J. Baird, J. A. Bandy, S. G. Davies, K. Prout, Chem. Commun., 1983, 1202
`(η5-C5H5)Ru(PPh3)H3: A Stable Ruthenium (IV) Trihydride.
`S. G. Davies, S. D. Moon, S. J. Simpson, Chem. Commun., 1983, 1278
`
`Elaboration of α-Substituted Benzyl Ethers and Sulphides by Suppression of the Wittig and Related
`Rearrangements.
`S. G. Davies, N. J. Holman, C. A. Laughton, B. E. Mobbs Chem. Commun., 1983, 1316
`Elaboration of Acyl Ligands: Preparation and Reactivity of the Anion [(η5-C5H5)Fe(CO)(PPh3)(COCH2)]-.
`S. G. Davies, N. Aktogu, H. Felkin, G. J. Baird, O. Watts, J. Organometal. Chem., 1984, 262, 49
`Electron-Rich η1-Cyano Complexes of Iron and Ruthenium: Preparation and Nucleophilic Properties.
`G. J. Baird, S. G. Davies, J. Organometal. Chem., 1984, 262, 215
`
`The Rate and Activation Parameters for the Cleavage of the Metal-Metal Bond of the Anion Radical of a Di-iron
`Carbonyl Complex.
`S. G. Davies, S. J. Simpson, V. D. Parker, Chem. Commun., 1984, 352
`
`Stereoselective Preparation of β-Amino-Acyl Iron Complexes for β-Lactam Synthesis.
`K. Broadley, S. G. Davies, Tetrahedron Lett., 1984, 25, 1743
`Carbon Monoxide Reduction: [Fe(η5-C5H5)(Ph2PCH2CH2PPh2)(CO)H]; Reactions and Formation by Reduction of the
`Complex [Fe(η5-C5H5)(Ph2PCH2CH2PPh2)(CO)]PF6.
`S. G. Davies, J. Hibberd, S. J. Simpson, S. E. Thomas, O. Watts, J. Chem. Soc., Dalton, 1984, 701
`
`Rules Governing Asymmetric Synthesis with Organotransition Metal Complexes.
`S. G. Davies, J. I. Seeman, Tetrahedron Lett., 1984, 25, 1845
`Hydride addition to the Cations [(η5-C5H5)Ru(L)2CO]+. (L = PPh3, L2 = Ph2PCH2CH2PPh2)
`S. G. Davies, S. D. Moon, S. J. Simpson, Nouveau J. Chimie, 1984, 8, 139
`A Convenient Synthesis of [Ru(η-C5H5)(PPh3)(CO)Cl] and the Cations [Ru(η-C5H5)(PPh3)L(CO)]+ [L=CO,
`PMe3, or P(OPh)3]
`S. G. Davies, S. J. Simpson, J. Chem. Soc.,Dalton, 1984, 993
`
`Stereoselective Synthesis of Erythro-β-Hydroxy Carboxylic Acids via Iron Acyl Complexes.
`S. G. Davies, I. M. Dordor, J. C. Walker, P. Warner, Tetrahedron Lett., 1984, 25, 2709
`Stereoselective Carbon-Carbon Bond Formation via Alkylation of [(η5-C5H5)Fe(PPh3)(CO)(COMe)=CHR)]
`(R = Me, Prn, Ph): X-Ray Crystal Structure of (Z)-[(η5-C5H5)Fe(PPh3)(CO)(COMe)=CHMe)].
`G. J. Baird, S. G. Davies, R. H. Jones, K. Prout, P. Warner, Chem. Commun., 1984, 745
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`Stereoselective Synthesis of Quaternary Carbon Atoms
`P. J. Curtis, S. G. Davies, Chem. Commun., 1984, 747
`Reductions of the Cations [(η5-C5H5)Fe(L)2CO]+ (L=tertiary phosphine): Product Control by Variation of
`Phosphine Ligands.
`S. G. Davies, S. J. Simpson, J. Organometal. Chem., 1984, 268, C53
`
`Chiral Acetate Enolate Equivalent for the Synthesis of β-Hydroxy Acids.
`S. G. Davies, I. M. Dordor, P. Warner, Chem. Commun., 1984, 956
`Conformational Analysis for the Alkyl Ligands (R) in Complexes of the Type (η5-C5H5)Fe(CO)(PPh3)R.
`J. I. Seeman, S. G. Davies, Chem. Commun., 1984, 1019.
`Stereoselective Additions to the Alkoxycarbene Cations [(η5-C5H5)Fe(CO)(PPh3)(=CROMe)]+ (R=H, Et).
`G. J. Baird, S. G. Davies, T. R. Maberly, Organometallics, 1984, 3, 1764.
`
`Titanium Catalysed Reduction of 1,2-Dibromides to Olefins.
`S. G. Davies, S. E. Thomas, Synthesis, 1984, 1027.
`
`Stereocontrolled Tandem Alkylations: Michael Additions and Subsequent Alkylations of α,β-Unsaturated Acyl
`Ligands bound to [(η5-C5H5)Fe(CO)(PPh3)].
`S. G. Davies, J. C. Walker, Chem. Commun., 1985, 209
`
`Stereoselective Synthesis of Cyclic Ethers via Bromine Assisted Epoxide Ring Expansion.
`S. G. Davies, M. E. C. Polywka, S. E. Thomas, Tetrahedron Lett., 1985, 26, 1461
`
`Chiral Propionate Enolate Equivalents for the Stereoselective Synthesis of Threo- or Erythro-α-Methyl-β-Hydroxy
`Acids.
`S. G. Davies, I. M. Dordor-Hedgecock, P. Warner, Tetrahedron Lett., 1985, 26, 2125.
`
`Chiral Propionate Enolate Equivalent for Stereoselective Additions to Symmetrical Ketones.
`P. W. Ambler, S. G. Davies, Tetrahedron Lett., 1985, 26, 2129.
`
`4-Substituted N-Methyl-1,2,3,4-tetrahydroisoquinolines: Synthesis via Stereoselective Substitution of Tricarbonyl-(N-
`methyl-1,2,3,4-tetrahydroisoquinoline)chromium.
`J. Blagg, S. G. Davies, B. E. Mobbs, Chem. Commun., 1985, 619.
`
`Chiral Acetate Enolate Equivalent for the Synthesis of β-Hydroxy Acids and Esters: X-Ray Crystal Structure of
`RR,SS-[η5-(C5H5)Fe(CO)(PPh3)(COCH2CH(OH)CH2CH3)].
`S. G. Davies, I. M. Dordor-Hedgecock, P. Warner, R. H. Jones, K. Prout, J. Organomet. Chem., 1985, 285, 213.
`
`Stereospecific Conversion of N,N-Dimethylamphetamine into N-Methylpseudoephedrine.
`J. Blagg, S. G. Davies, Chem. Commun., 1985, 653.
`Bimetallic Cyano-bridged Cations: Preparation and Hydride Reduction of [(η5C5H5)L2Ru(µ-CN)ML'2(η5-C5H5)PF6
`[L2,L'2 = (PPh3)2; Ph2PCH2CH2PPh2; M = Ru or Fe]. Formation of [Ru(η5-C5H5)(PPh3)H3] and X-ray Crystal
`Structure of [(η5-C5H5)(Ph2PCH2CH2PPh2)Ru(µ-CN)Ru(PPh3)2(η5-C5H5)]PF6-
`G. J. Baird S. G. Davies, S. D. Moon, S. J. Simpson, R. H. Jones, J. Chem. Soc., Dalton, 1985, 1479
`
`Base Promoted Rearrangements of Cyclopentadienylacyl and Carboxyalkyl-metal Complexes.
`S. Abbott, G. J. Baird, S. G. Davies, I. M. Dordor-Hedgecock, T. R. Maberley, J. C. Walker, P. Warner, J. Organometal.
`Chem.,1985, 289, C13
`Chiral Discrimination in the Reactions of the Enolate E-[(η5-C5H5)Fe(CO)(PPh3)COCHMe]- Li+ with cis- and
`trans-But-2-ene oxides in the presence of BF3-OEt2.
`S. G. Davies, P. Warner, Tetrahedron Lett., 1985, 26, 4815
`Chiral discrimination in the Reaction of the Enolate [(η5-C5H5)Fe-(CO)(PPh3)(COCH2)]- Li+ with Monosubstituted
`Epoxides: X-Ray Crystal Structure of (RS,SR)-[(η5-C5H5)Fe(CO)(PPh3){COCH2CH2CH-(OH)Me}]
`S. L. Brown, S. G. Davies, P. Warner, R. H. Jones, K. Prout, Chem. Commun., 1985, 1446
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`71.
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`72.
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`73.
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`74.
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`75.
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`76.
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`77.
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`78.
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`79.
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`80.
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`81.
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`82.
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`83.
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`84.
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`85.
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`86.
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`87.
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`Conformational-Reactivity Relationships for the Organotransition-Metal Complexes (η5-C5H5)Fe(CO)(PPh3)R and
`(η5-C5H5)Re(NO)(PPh3)R (R=Alkyl and Aryl)
`J. I. Seeman, S. G. Davies, J. Am. Chem. Soc., 1985, 107, 6522
`
`Mechanism of the Formation of Methyliron Complexes by Protonation of Methoxymethyliron Complexes.
`S. G. Davies, T. R. Maberly, J. Organomet. Chem., 1985, 296, C37.
`Synthesis of α,β-Unsaturated Acyl Ligands bound to the Chiral Auxiliary [(η5-C5H5)Fe(CO)(PPh3)].
`S. G. Davies, R. J. C. Easton, J. C. Walker, P. Warner, J. Organomet. Chem., 1985, 296, C40.
`Conformational Analysis of Compounds of the Type [Fe(η5-C5H5)(CO)(PPh3)(CH2R)] (R=Alkyl or aryl).
`S. G. Davies, J. I. Seeman, J. Chem. Soc., Dalton, 1985, 2691.
`
`Resynthesis of Histone Peptide Bonds on a DNA Matrix.
`S. G. Davies, I. O. Walker, P. N. Schofield, in "Chromosomal Proteins and Gene Expression", Eds. G. R. Reeck, G. H.
`Goodwin and P. Puigdomenech, NATO-ASI Series Plenum, New York, 1985, 101, 17.
`
`Reductive Polymerisation of Carbon Monoxide: Synthesis of Entirely CO-derived Pentanoic Acid.
`S. L. Brown, S. G. Davies, Chem. Commun., 1986, 84.
`Conformational Analysis of the Iron Acetyl Complex [(η5-C5H5)Fe(CO)(PPh3)COCH3].
`S. G. Davies, J. I. Seeman, I. H. Williams, Tetrahedron Lett., 1986, 27, 619.
`Improved Stereochemical Control and Mechanistic Aspects of the Alkylation of Enolates Derived from [(η5-
`C5H5)Fe(CO)(PPh3)COCH2R].
`S. L. Brown, S. G. Davies, D. F. Foster, J. I. Seeman, P. Warner, Tetrahedron Lett., 1986, 27, 623.
`Synthesis and Characterisation of E and Z α,β-Unsaturated Acyl Complexes [(η5-C5H5)Fe(CO)(PPh3)-
`(COCH=CHR)] (R=H, Me, Et, n-Bu, t-Bu, Ph, vinyl, 2-furyl).
`S. G. Davies, R. J. C. Easton, J. C. Walker, P. Warner, Tetrahedron, 1986, 42, 175.
`
`The Stereoselective Synthesis of (-)-(8R)-Methylcanadine via Selective Monocomplexation of Canadine to Chromium
`Tricarbonyl.
`J. Blagg, S. G. Davies, Chem. Commun., 1986, 492
`
`Stereoselective Synthesis of Quaternary Carbon Centres
`S. G. Davies, J. C. Walker, Chem. Commun., 1986, 495
`Determination of the Absolute Configuration and Optical Purity of [(η5-C5H5)Fe(CO)(PPh3)COMe]; X-Ray
`Crystal Structure of (R)-[(η5-C5H5)Fe(CO)(PPh3)COCH2CH2O[(R)-menthyl]].
`S. G. Davies, I. M. Dordor-Hedgecock, K. H. Sutton, J. C. Walker, C. Bourne, R. H. Jones, K. Prout, Chem. Commun.,
`1986, 607
`Asymmetric Diels-Alder Reactions: (S)-(+)-[(η5-C5H5)Fe(CO)(PPh3)COCH=CH2] as a Chiral Acrylate Dienophile
`Equivalent.
`S. G. Davies, J. C. Walker, Chem. Commun.,1986, 609
`Bromo(η5-cyclopentadienyl)[1,2-ethanediylbis(diphenylphosphine)]iron and Bromo(η5-cyclopentadienyl)[1,2-
`ethanediylbis(diphenylphosphine)]bis(tetrahydrofuran)ironmagnesium. (Fe-Mg)
`S. G. Davies, H. Felkin, O. Watts, Inorganic Syntheses, 1986, 24, 170
`
`Synthesis of Cyclic Ethers via Bromine Assisted Epoxide Ring Expansion.
`S. G. Davies, M. E. C. Polywka, S. E. Thomas, J. Chem. Soc., Perkin Trans. 1, 1986, 1277
`
`Chiral Dienolates: Stereoselective Formation and α-Alkylation of the Lithium Dienolates Derived from (RS)-Z-
`[(η5-C5H5)Fe(CO)(PPh3)COCH=CHCH2R](R=Me, Et, n-Pr) and (RS)-[(η5-C5H5)Fe(CO)(PPh3)-
`(COCH=CMe2)].
`S. G. Davies, R. J. C. Easton, A. Gonzalez, S. C. Preston, K. H. Sutton, J. C. Walker, Tetrahedron, 1986, 42, 3987
`
`Organometallics in Synthesis: Part I: The Transition Elements,
`S. G. Davies, S. E. Thomas, SPR Gen. and Synth. Methods., Ed. G. Pattenden, 1986, 8, 312.
`
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`88.
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`89.
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`90.
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`91.
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`92.
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`93.
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`94.
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`95.
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`The Asymmetric Synthesis of β-Lactams. Stereocontrolled Asymmetric Tandem Michael Additions and Akylations of
`α,β-Unsaturated Acyl Ligands Bound to the Chiral Auxiliary [(η5-C5H5)Fe(CO)(PPh3)].
`S. G. Davies, I. M. Dordor-Hedgecock, K. H. Sutton, J. C. Walker, Tetrahedron Lett., 1986, 27, 3787
`
`Stereoselective Synthesis via Arene Chromium Tricarbonyl Complexes
`S. G. Davies, Chem. and Ind., 1986, 506
`
`Homogeneous Reduction of Carbon Monoxide.
`S. L. Brown, S. G. Davies, S. J. Simpson, S. E. Thomas, Applied Catalysis, 1986, 25, 87
`Regioselective Nucleophilic Additions to (η6-Benzyl alcohol)tricarbonylchromium: Isolation and X-Ray Crystal
`Structure of the Intermediate (η6-5-Methylene-6-exo-t-butylcyclohexa-1,3-diene)tricarbonylchromium.
`J. Blagg, S. G. Davies, C. L. Goodfellow, K. H. Sutton, Chem. Commun., 1986, 1283
`
`Elaboration of α-Substituted Benzyl Alkyl Ethers and Sulphides by Suppression of the Wittig and Related
`Rearrangements via Complexation to Tricarbonylchromium.
`J. Blagg, S. G. Davies, N. J. Holman, C. A. Laughton, B. E. Mobbs, J. Chem. Soc., Perkin Trans. 1, 1986, 1581
`
`The Asymmetric Synthesis of β-Lactams. Stereocontrolled Asymmetric Tandem Michael Additions and Subsequent
`Alkylations of E-[(η5-C5H5)Fe(CO)-(PPh3)COCH=CHMe]. X-Ray Crystal Structure of (RS)-E-[(η5-C5H5)Fe-
`(CO)(PPh3)COCH=CHMe].
`S. G. Davies, I. M. Dordor-Hedgecock, K. H. Sutton, J. C. Walker, R. H. Jones, K. Prout, Tetrahedron, 1986, 42, 5123
`Stereoselective Reduction of (R,S)-[(η5-C5H5)Fe(CO)(PPh3)(=COCH2CH2CMe2)]+ and Complete Epimerisation of
`the Kinetic (RR,SS)-Diastereoisomer to the Thermodynamic (RS,SR)-Diastereoisomer of the Product [(η5-
`C5H5)Fe(CO)(PPh3){C(H)OCH2CO2CMe2}].
`A. P. Ayscough, S. G. Davies, Chem. Commun., 1986, 1648
`
`Tetrahydroisoquinolines Part 2. Synthesis of 4-Substituted N-Methyl-l,2,3,4-tetrahydroisoquinolines via Regio- and
`Stereo-selective Elaboration of Tricarbonyl(N-methyl-1,2,3,4-tetrahydroisoquinoline)chromium
`J. Blagg, S. J. Coote S. G. Davies, B. E. Mobbs, J. Chem. Soc., Perkin Trans. 1, 1986, 2257
`Conformational Analysis and X-ray Crystal Structure of [(η5-C5H5)Fe(CO)(PPh3)CH2CH3].
`S. G. Davies, I. M. Dordor-Hedgecock, K. H. Sutton, M. Whittaker, J. Organometal. Chem., 1987, 320, C19.
`Chiral Dienolates: Formation and Stereoselective α-Alkylation of the Lithium Dienolate Derived from (Z)-[(η5-
`C5H5)Fe(CO)(PPh3)COCH=CHMe]. X-Ray Crystal Structure of (RS)-(Z)-[(η5-C5H5)Fe(CO)(PPh3)-
`COCH=CHMe].
`S. G. Davies, R. J. C. Easton, K. H. Sutton J. C. Walker, R. H. Jones, J. Chem. Soc., Perkin Trans. 1, 1987, 489
`
`Tetrahydroisoquinolines. Part 3. Stereoselective Synthesis of cis- and trans-1,4-Disubstituted N-Methyl-1,2,3,4-
`tetrahydroisoquinolines as their Tricarbonylchromium Complexes.
`J. Blagg, S. J. Coote, S. G. Davies, D. Middlemiss, A. Naylor, J. Chem. Soc., Perkin Trans. 1, 1987, 689
`Conformational Analysis and X-ray Crystal Structure of [(η5-C5H5)Fe(CO)(PPh3)CH2SiMe3].
`S. G. Davies, I. M. Dordor-Hedgecock, K. H. Sutton, M. Whittaker, Chem and Ind., 1987, 338.
`
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`96.
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`97.
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`98.
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`99.
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`100. Organometallics in Synthesis: Part I "The Transition Elements".
`J. Blagg, S. G. Davies, P. F. Gordon, SPR Gen. and Synth. Methods. Ed. G. Pattenden, 1987, 9, 398.
`
`
`101. An Approach to the Stereoselective Synthesis of α-Hydroxycarboxylic Acids.
`S. G. Davies, M. Wills, J. Organometal. Chem., 1987, 328, C29
`
`
`102.
`
`The Diastereoselective Functionalisation of Arene Tricarbonylchromium Complexes Containing a Benzylic Heteroatom
`Substituent.
`J. Blagg, S. G. Davies, C. L. Goodfellow, K. H. Sutton, J. Chem. Soc., Perkin Trans. 1, 1987, 1805.
`Synthesis and Stereoselective Reactions of α,β-Unsaturated Acyl Ligands Bound to the Chiral Auxiliary [(η5-
`C5H5)Fe(CO)(PPh3)]: A review.
`S. G. Davies, I. M. Dordor-Hedgecock, R. J. C. Easton, S. C. Preston, K. H. Sutton, J. C. Walker, Bull. Soc. Chim. Fr.,
`1987, 608.
`
`
`
`103.
`
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`104.
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`105.
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`106.
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`Conformational Analysis of [(η5-C5H5)Fe(CO)(PPh3)CH2OMe]: Solvent Dependence of Conformer Populations.
`B. K. Blackburn, S. G. Davies, M. Whittaker, Chem. Commun., 1987, 1344
`Conformational Analysis for the Pseudooctahedral Complexes (η5-C5H5)Fe(CO)(PPh3)CH2R [R=Me, Et, i-Pr, t-Bu,
`SiMe3, (PMe3)+, (PPh3)+, Mesityl, Ph, vinyl, l-Naphthyl]: X-Ray Crystal Structures of (η5-C5H5)Fe-
`(CO)(PPh3)CH2R (R = Me, SiMe3)
`S. G. Davies, I. M. Dordor-Hedgecock, K. H. Sutton, M. Whittaker, J. Am. Chem. Soc., 1987, 109, 5711
`
`The Highly Stereoselective Conversion of N,N-Dimethylamphetamine into N-Methylpseudoephedrine; a Mimic of the
`Enzyme Mediated Stereospecific Benzylic Hydroxylation of 2-Arylethylamines.
`J. Blagg, S. G. Davies, Tetrahedron, 1987, 43, 4463
`
`
`
`107. Nucleophilic Attack on Unsaturated Hydrocarbons Coordinated to Transition Metals.
`S. G. Davies, M. L. M. Green, D. M. P. Mingos in "Reactions of Coordinated Ligands" Ed. P. S. Braterman,
`
`Plenum, New York, 1986, 1, 897
`
`
`Stereospecificity of the Rearrangement of the α-Alkoxy Iron Acyl [(η5-C5H5)Fe(CO)(PPh3)COCH2OCH2Ph] to the α-
`108.
`Metalla-ester [(η5-C5H5)Fe(CO)(PPh3)CH2CO2CH2Ph].
`S. G. Davies, M. Wills, Chem. Commun., 1987, 1647
`The Asymmetric Synthesis of (-)-Captopril utilising the Iron Chiral Auxiliary [(η5-C5H5)Fe(CO)(PPh3)].
`G. Bashiardes, S. G. Davies, Tetrahedron Lett., 1987, 28, 5563
`
`Substituted 4H-l-Benzopyran-4-ones (Chromones): Synthesis via Palladium Catalysed Coupling of their Halogeno
`Derivatives with Alkenes
`S. G. Davies, B. E. Mobbs, C. J. Goodwin, J. Chem. Soc., Perkin Trans. 1, 1987, 2597
`
`
`
`109.
`
`
`110.
`
`
`
`111.
`The Stereospecific Synthesis of (-)-(8R) and (-)-(8S)-Methylcanadine.
`P. D. Baird, S. G. Davies, J. Blagg, K. H. Sutton, Tetrahedron, 1988, 44, 171
`
`
`112. Asymmetric Synthesis via the Iron Chiral Auxiliary [(η5-C5H5)Fe(CO)(PPh3)].
`S. G. Davies, Pure and Applied Chemistry, 1988, 60, 13
`
`
`113. Asymmetric Synthesis of (1R,8S)- and (lS,8S)-l-Hydroxypyrrolizidin-3-ones from Boc-L-Prolinal and (S)- and (R)-[(η5-
`C5H5)Fe(CO)(PPh3)(Ac)], respectively.
`R. P. Becket, S. G. Davies, Chem. Commun., 1988, 160
`
`
`
`114.
`
`
`
`115.
`
`
`
`
`116.
`
`Stereoselective Synthesis of Arenechromium Tricarbonyl Complexes: Origins of the Benzylic Oxygen Directing
`Effects for l-Tetralol Derivatives
`S. G. Davies, C. L. Goodfellow, J. Organometal. Chem., 1988, 340, 195
`
`Stereochemical Studies on Marine Cyclic Peroxides: An Unequivocal Assignment of Absolute Stereochemistry by
`Asymmetric Synthesis.
`R. J. Capon, J. K. Macleod, S. J. Coote, S. G. Davies, G. L. Gravatt, I. M. Dordor-Hedgecock, M. Whittaker,
`Tetrahedron, 1988, 44, 1637
`
`Complementary Stereoselective Cyclisations of N-(3,4-Dimethoxy-benzyl)ephedrine and its Chromium Tricarbonyl
`Complex to trans- and cis-2,3-Dimethyl-4-phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines Respectively.
`S. J. Coote, S. G. Davies, Chem. Commun., 1988, 648
`
`Tetrahydroisoquinolines. Part 4. Enantioselective Conversion of (+)-Amphetamine into (+)-(lR,3S,4S)- and (-)-
`(lS,3S,4R)-1,2,3,4-Tetra