Association for Research in Vision and Ophthalmology
`
`Summer Newsletter 2007
`
`MESSAGE FROM THE PRESIDENT
`
`MARTINE J. JAGER, MD, PhD
`
`ARVO Expands Global Activities
`ARVO is doing well.
`with the next meeting scheduled for 2009,
`this time in Hyderabad, India.
`
`It has developed
`into a global eye research
`organization with over
`12,000 members and a
`yearly meeting, which
`in 2007 attracted over
`10,000 attendees. The
`fact that ARVO has for the first time
`an international member as president is
`further proof of its international growth,
`as is the current presence of three
`international members
`on the ARVO Board of
`Trustees. ARVO has truly
`become an international
`organization, with the
`development of chapters
`and collaborations with
`other eye organizations around the world.
`The first ARVO International Chapter
`Affiliate Council was held this year and,
`as chapters are a very useful instrument to
`stimulate research collaboration and raise
`money for research, I expect that many
`other countries will also start their own
`chapters. The Asia-ARVO meeting in
`Singapore was once again a great success,
`
`… the US is a role model
`for many other countries in
`the proper support of eye
`and vision research.
`
`Advocacy
`Advocacy is an essential focus of ARVO
`and we receive continuous support from
`AEVR/NAEVR. The importance of
`lobbying cannot be underestimated, and
`I think that the US is a role model for
`many other countries in the proper sup-
`port of eye and vision research. As support
`from NIH is essential for the continuation
`of eye research in the
`US, efforts to increase
`money for research is of
`the greatest importance.
`Only with proper sup-
`port for young investiga-
`tors will (eye) research
`continue to be a goal in life for those
`considering a scientific career. In many
`countries eye research is hardly supported
`by the local government. Only by first
`showing the importance of eye diseases
`in different regions of the world by good
`epidemiological studies can researchers
`convince their governments to invest in
`
`See President’s Message, page 
`
`Board of Trustees, May 2007
`
`ARVO
`at Other Meetings
`Visit the ARVO Exhibits and attend ARVO
`Symposia at the following:
`
`European Association for Vision and Eye
`Research (EVER)
`Portoroz, Slovenia
`October 3–6, 2007
`
`American Academy of Optometry
`Tampa, Florida
`October 24–27, 2007
`Booth 717
`
`American Academy of Ophthalmology
`New Orleans, Louisiana
`November 10–13, 2007
`Booths 5341–5343
`
`See page 17 for details.
`
`ARVO Governance
`Around the Globe
`2008 Annual Meeting
`2007 Annual Meeting Highlights
`ARVO Advocacy
`ARVO Education Programs
`ARVO Membership News
`JOV
`IOVS
`NEI/NIH News
`Awards and Grants
`The ARVO Foundation for Eye Research
`
`2
`5
`8
`12
`14
`17
`18
`21
`22
`23
`25
`26
`
`Annual Meeting Survey Results
`More than 800 attendees responded
`ideas for projects and future employment.”
`Another attendee commented, “This
`was my first ARVO
`experience and it was
`excellent! Not only was
`it informative but also
`very enjoyable.”
`Suggestions about the
`meeting publications,
`including the Program
`Summary Book and
`online and CD-ROM
`versions of the Abstract
`Search and Itinerary
`Builder, will be considered. Additional
`See Survey, page 
`
`to the 2007 Annual Meeting survey
`and provided important
`feedback about the sci-
`entific program, publica-
`tions, and services.
`Ninety-three percent of
`respondents indicated
`that the Annual Meeting
`met or exceeded their
`expectations, and 91%
`ranked the quality of
`the scientific program
`as excellent or good.
`One respondent noted, “I met so many
`interesting people and got lots of great
`
`Concerns Raised and
`Being Addressed
`Building Temperature
`Missing Message Center
`Meeting Publications
`Abstract Search/Itinerary
`Builder
`
`n n n n
`
`Mylan Exhibit 1059
`Mylan v. Regeneron, IPR2021-00880
`Page 1
`
`

`

`2007–2008
`Officers
`
`Martine J. Jager, MD, PhD
`President
`
`Robert Ritch, MD
`Vice President
`
`Todd P. Margolis, MD, PhD
`President-Elect
`
`Donald C. Hood, PhD
`Vice President-Elect
`
`Barry S. Winkler, PhD
`Vice President-Elect
`
`Sally S. Atherton, PhD
`Executive Vice President
`
`ArVO Office
`
`Joanne G. Angle
`Executive Director
`
`Karen Schools Colson
`Director of Publishing & Communications
`
`John Saville
`Production & Design Director
`
`12300 Twinbrook Parkway
`Suite 250
`Rockville, MD 20852-1606
`Phone: (240) 221-2900
`Fax: (240) 221-0370
`www.arvo.org
`
`GOVERNANCE
`
`New Trustees Elected at 2007 Annual Meeting
`The BI, CL, and VN Sections held Trustee elections this year. The response rate for
`
`all Sections was well over 30 percent, with almost 80 percent of all votes registered
`online. The newly-elected Trustees are:
`
`The Biochemistry/Molecular Biology (BI) Section elected
`Jeffrey H. Boatright, PhD, to a five-year term. Dr. Boatright is an
`Associate Professor in the Department of Ophthalmology at Emory
`University School of Medicine in Atlanta, GA. He has been an
`ARVO member since 1989, and has served on ARVO’s Annual
`Meeting Program Committee, the Public Policy Network, and as a
`Travel Grant Reviewer.
`
`The Clinical/Epidemiologic Research (CL) Section elected
`Paul Mitchell, MD, PhD, to a five-year term. Dr. Mitchell is Professor,
`Department of Ophthalmology, University of Sydney; Director of
`Ophthalmology, Sydney West Area Health Service, Westmead
`Hospital; and Director, Centre for Vision Research, Westmead
`Millennium Institute in Sydney, Australia. He has been an ARVO
`member since 1990, and has also served on ARVO’s Annual Meeting
`Program Committee and the Awards Committee.
`
`The Visual Neurophysiology (VN) Section elected Robert F. Miller,
`MD, to a five-year term. Dr. Miller is the 3M Bert Cross Chair in
`Visual Neuroscience in the Department of Neuroscience at the
`University of Minnesota in Minneapolis, MN. He has been an ARVO
`member since 1969. n
`
`Trustee Nominations for 2008
`At business meetings held during the 2007 ARVO Annual Meeting, the following
`
`Sections nominated candidates to stand for election as Trustees in 2008:
`AP Section: Hans E. Grossniklaus, MD, MBA, Emory University, Atlanta, GA
`Jacob Pe’er, MD, Hadassah-Hebrew University Medical Center, Jerusa-
`lem, Israel
`GL Section: Peng T. Khaw, MD, PhD, Moorfields Eye Hospital, London, England
`Louis R. Pasquale, MD, Massachusetts Eye & Ear Infirmary,
`Boston, MA
`The 2008 Trustee elections will be conducted using an online election system, which
`has proven to be quite successful over the past few years. Only voting members of the
`Sections with nominees will be eligible to take part in the 2008 elections. n
`
`ARVO Thanks Outgoing Committee Chairs and
`Volunteers
`ARVO extends its thanks to all members who served on committees this past year.
`
`Special thanks go out to those who completed their terms as Chair this year:
`Alan D. Marmorstein, PhD (Advocacy’s Scientific Policy Subcommittee); James E.
`Puklin, MD (Advocacy’s International Advocacy Subcommittee); Carol B. Toris, PhD
`(Animals in Research); Joseph L. Demer, MD, PhD (Awards); Gail M. Seigel, PhD
`(Diversity Issues); Dwight Stambolian, MD, PhD (Ethics and Regulations in Human
`Research); Donald T.H. Tan, FRCS (International Members); Gary W. Abrams, MD
`(Long Range Planning); and David C. Beebe, PhD (Publications). n
`
`2
`
`ARVONewS Summer 2007
`
`
`
`www.arvo.org
`
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`Mylan v. Regeneron, IPR2021-00880
`Page 2
`
`

`

`GOVERNANCE
`
`Spotlight On Committee Activities
`ARVO’s Committees develop and implement specific programs and projects that address
`
`the long-range goals of ARVO. In this edition of ARVONews we will focus on the
`work of three Committees.
`
`Diversity Issues Committee
`The Diversity Issues Committee (DIC), chaired by Laura Robles,
`PhD, is pursuing ways to augment ARVO’s participation in the Society
`for Advancement of Chicanos and Native American in Science
`(SACNAS) Annual Conference, the Annual Biomedical Research
`Conference for Minority Students (ABRCMS), and the National
`Medical Association (NMA) Annual Meeting. Funds have been
`budgeted in 2008 for ARVO to award prizes at each conference. Prizes
`include a travel grants to the ARVO Annual Meeting for the best
`presenters at each meeting and ARVO T-shirts and certificates for the other top presenters.
`The Committee intends to have at least one member on site at each of these meetings.
`As an adjunct to increased involvement in the above-mentioned conferences, the DIC,
`in collaboration with the Members-in-Training Committee, is developing a brochure on
`careers in eye and vision research, which will include information about ARVO member-
`ship, the Annual Meeting, brief descriptions of the types of careers pursued by ARVO
`Members (with Member testimonials), and educational requirements needed to pursue a
`career in vision and vision research.
`
`Animals in Research Committee
`Based on the recommendation of the Animals in Research Committee
`(ARC), chaired by Catherine Thut, PhD, the ARVO Board of Trustees
`approved ARVO joining the National Association for Biomedical
`Research’s (NABR) Legal Strategy Group, a legal team that works with
`universities whose researchers come under attack. Specifically, the Group
`works with the legal and public outreach departments of universities to
`develop education programs on the use of animals in research and teach
`how to respond to attacks on the faculty who use animals in their research.
`The Group is also working with NIH to include a check-off box on grant application forms for
`universities to indicate a clear understanding that if NIH funds are received, the university is
`required to take responsibility for their researchers if they come under attack.
`The ARC is reviewing international standards for possible incorporation into ARVO’s
`“Statement for the Use of Animals in Ophthalmic and Visual Research.” The ARC also
`encourages all non-US ARVO members to consider joining the European Biomedical
`Research Association (EBRA), an association of individuals and organizations in the
`scientific, medical, and veterinary professions in Europe. More information can be found at
`www.ebra.org.
`
`Commercial Relationships Committee
`Todd P. Margolis, MD, PhD, ARVO President-Elect and Commercial
`Relationship Committee (CRC) Chair recently represented ARVO on
`a panel of experts convened by the Federation of American Societies
`in Experimental Biology (FASEB). The panel has developed an online
`conflict of interest (COI) toolkit for managing financial relationships be-
`tween academia and industry in all fields of biomedical research. The COI
`Toolkit specifically addresses the conduct of research (including clinical
`trial registration), publishing, mentoring, etc.
`This spring, the CRC provided input on the first draft of the Toolkit. After reviewing the
`final draft, the CRC, Publications Committee, and the Ethics and Regulations in Human
`Research Committee recommended that the ARVO Board of Trustees endorse the Toolkit
`and approve posting a link to the Toolkit on the ARVO Web site. Look for the link in the
`“Other Resources” section at www.arvo.org. n
`
`www.arvo.org
`
`
`
`2007–2008
`Committee Chairs
`
`The following have been named
`as ARVO Committee Chairs for this
`coming year. Go to www.arvo.
`org/committee for Committee
`descriptions and activities:
`Advocacy Committee
`Barry S. Winkler, PhD
`Animals in Research Committee
`Catherine Thut, PhD
`Annual Meeting Program Committee
`Sally S. Atherton, PhD
`Awards Committee
`Reza Dana, MD, MPH, MSc
`Commercial Relationships Committee
`Todd P. Margolis, MD, PhD
`Diversity Issues Committee
`Laura J. Robles, PhD
`Ethics and Regulations in Human
`Research Committee
`Leonard A. Levin, MD, PhD
`Exhibits Committee
`Thomas R. Friberg, MD
`Finance Committee
`Donald C. Hood, PhD
`International Members Committee
`Robert Ritch, MD
`Long Range Planning Committee
`Frederick L. Ferris, III, MD
`Members-in-Training Committee
`John Paul SanGiovanni, ScD
`Professional Development and
`Education Committee
`Maureen G. Maguire, PhD
`Publications Committee
`Nicholas A. Delamere, PhD
`Volunteer Management Committee
`Todd P. Margolis, MD, PhD
`
`Volunteer!
`Share your expertise and play a part
`in shaping ARVO’s goals and future.
`Volunteer to be on your favorite
`ARVO Committee. Read more about
`the wide variety of opportunities
`and complete an online Committee
`Volunteer Form on the ARVO
`Committees’ home page at www.
`arvo.org/committee.
`
`ARVONewS Summer 2007 3
`
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`Mylan v. Regeneron, IPR2021-00880
`Page 3
`
`

`

`GOVERNANCE
`
`Proposed Bylaws
`Amendment to Update
`Section Trustee Nomination
`Process
`In 2005, ARVO began taking Section Trustee
`Nominations in advance of the Section Business
`Meetings held each year at ARVO in an
`effort to increase the number of candidates
`to nominate. Individuals still had the option
`to nominate candidates from the floor of the
`Business Meeting. Since ARVO implemented this
`process, the number of nominations received in
`advance of the Section Business Meeting has
`increased. Therefore, it is questionable as to
`whether there is a need to continue accepting
`nominations on the floor of the Section Business
`Meetings.
`At the General Business Meeting of the
`2008 Annual Meeting, the ARVO membership
`will vote to amend the ARVO bylaws to
`adopt an online electronic voting method to
`nominate the two Section Trustee candidates in
`advance of the Section Business Meetings. The
`candidates will be announced at the Section
`Business Meetings.
`100 votes are required to amend the ARVO
`bylaws, so we strongly encourage you to attend
`the 2008 General Business Meeting in Fort
`Lauderdale.
`
`The Proposed bylaws amendment is listed
`below:
`5.03 Election. (a) Nomination of Trustees.
`During the course of each Annual Meeting of
`ARVO, each Scientific Section of ARVO shall
`hold a separate business meeting. By the end
`of the first day of the ARVO Annual Meeting, At
`the separate business meeting, each standing
`Scientific Section whose Trustee’s term of office
`will expire at the end of the following year’s
`Annual Meeting shall nominate by online vote
`no more than two (2) candidates. The two
`candidates will be announced at the separate
`business meeting. o One of whom candidate will
`be elected as the Successor Trustee by an online
`electronic election prior to the following year’s
`Scientific Section’s separate business meeting,
`which will take place at the Annual Meeting.
`
`ARVO Gearing Up to Develop New
`Long-Range Plan
`This October, the ARVO Board of
`
`Trustees will meet with the ARVO
`Strategic Planning Group, chaired by Rick
`Ferris, MD, to begin developing ARVO’s
`next five-year strategic plan.
`Much has been accomplished under the
`last strategic plan (created in 200) that
`has benefited the ARVO membership and
`the eye and vision research community as
`a whole. The plan has led to the imple-
`mentation of international chapter affili-
`ates and collaborations with numerous eye
`organizations to continue advancing vision
`research around the world. New programs
`
`and activities also have been launched to
`support the work of clinician-scientists in
`eye and vision research and cross-sectional
`scientific interests. A complete list of all
`the accomplishments under the last stra-
`tegic plan is available on the ARVO Web
`site at www.arvo.org/strategic.
`ARVO would like to thank the mem-
`bers who provided input on the future
`direction of ARVO through the member
`survey sent in August. Your comments and
`suggestions are vital in planning ARVO’s
`future and will be discussed at the October
`Strategic Planning Meeting. n
`
`President’s Message, continued from page 
`
`eye research. With the increase in elderly
`people in the world, it is certain that
`age-related eye problems such as macular
`degeneration and corneal problems will
`occur in more patients; with the incred-
`ible new surgical techniques for corneal
`diseases and the medical possibilities for
`the macula, very many clinical compara-
`tive studies will be necessary. The further
`identification of the genetic basis of
`diseases will make it possible to identify
`the pathobiological basis of many diseases
`which may lead to better preventive
`measures. These topics and many more in
`any field of ocular research are fascinating,
`but in order to perform studies, research
`money is needed. ARVO will do its best
`to help researchers anywhere learn how
`to raise money for research and will also
`help with the development of educational
`sessions on clinical trials.
`
`International Travel Grants
`Internationally, ARVO has reached out
`to its young researchers by expanding its
`own travel grant program and by collabo-
`rating with industry and private individu-
`als to create more travel grants for those
`who otherwise could not afford to come
`to the ARVO annual meetings. In 2008,
`ARVO will award 100 travel grants to
`researchers from outside the US. The
`incredible number of applications shows
`the popularity of this program, and the
`ARVO office will continue to put a lot of
`effort into managing and expanding it.
`ARVO exists as a base of support for
`eye researchers. If you have any ideas to
`further stimulate our goal of improving
`eye research, please let us know. The
`Association is here for you. n
`
`Martine J. Jager, MD, PhD
`
`Surveys, continued from page 
`
`comments were provided about the
`Annual Meeting location, audiovisual
`services, and meeting services and activi-
`ties. Excellent comments were offered
`about ARVO’s complimentary shuttle
`bus service to and from the Convention
`Center. In particular, feedback about
`the cold temperature in the Convention
`Center and the lack of a Message Center
`were viewed as critical. All of these areas
`
`will be reviewed and concerns will be
`addressed in the planning process for the
`2008 Annual Meeting.
`All feedback about the Annual
`Meeting is welcome. If you have sug-
`gestions about the Annual Meeting,
`or would like to propose an ARVO
`Education Course, Summer Eye Research
`Conference, or other educational pro-
`gram, contact Ellyn Terry, Director of
`Meetings and Education, at eterry@arvo.
`org. n
`
`
`
`ARVONewS Summer 2007
`
`
`
`www.arvo.org
`
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`Mylan v. Regeneron, IPR2021-00880
`Page 4
`
`

`

` THE GLOBE
`
`Indo–US Workshop to Generate Collaborations
`Interest in generating additional research collaborations between India and US research-
`
`ers brought together a group of established and prospective collaborators at the 2007
`ARVO Annual Meeting. Chaired by Drs. D. Balasubramanian and P. Kaufman, the
`participants heard Dr. P. Sieving support the collaborations and emphasize the National
`Eye Institute’s (NEI) interest in studies vis-à-vis the phenotype profiles in the two
`countries. Dr. L. Aiello spoke about the diabetic retinopathy clinical research
`(DRCR) project and how Indian groups under the leadership of Aravind are
`participating. Drs. G. Dagnelie and R. Tandon introduced the bi-national effort
`on genetic predisposition and antioxidant trials that they hope to have funded
`through the NEI in the US and the Department of Biotechnology (DBT) in India.
`
`Joint grants scenarios
`Dr. T.S. Rao of the DBT and Dr. L. Ellwein of NEI focused on three types of joint
`grant proposals: (i) Asking for funds from NIH where supplementary amounts
`are asked for the Indian partners (Dr. D. Beebe and Dr. J. Costello work with Dr.
`Balasubramanian under this arrangement). (ii) Joint proposals submitted simul-
`taneously to NIH and to DBT: the joint pre-proposal (short summary of what is
`intended) is first seen and agreed to by the Joint Working Group (JWG), which
`is composed of eye researchers representing the two governments. The next step
`is to submit the joint proposal to both NIH and DBT so that proposals are funded
`by the respective governments. The Dagnelie/Indian group is an example. (iii)
`For a project already funded for the US partner, such as through an ongoing R01,
`the Indian partner adds his part and sends the proposal to the DBT, which reviews
`it via the Indian JWG, and then processes it for possible funding, such as the
`Aravind/Aiello DRCR project.
`
`Material transfer
`Under the 200 Agreement to Expand Vision Research Collaborations signed by
`the US and Indian governments, and the work by Dr. T.S. Rao of the DBT, the
`exchange of human biological material between the two countries has become far
`simpler and faster. A single window clearance from the DBT suffices; all that the
`researchers need to give is a short write-up justifying the need and the amount of
`material.
`
`Exchange of researchers
`Dr. T.S. Rao talked about the facility for exchanging researchers through the
`existing DBT’s Visiting Scientist from Abroad Program (VSAP), and the Overseas
`Associate Program (OAP) for Indians. It is very likely that DBT will designate
`three to four such visits each year, each way. Drs. J. Bennett and M. Friedlander
`will be going to India, thanks to VSAP, while a member of the Sankara staff is in
`the US through the OAP. Note that this dual scheme is funded totally by DBT.
`
`Sending US medicos to India
`Talks have been initiated between Dr. Balasubramanian and NIH’s Fogarty Center
`to re-establish a program for post-third-year MD students to spend a year abroad in
`Indian eye centers.
`
`Workshops to kindle and sustain interest
`In addition to holding workshops at the ARVO Annual Meeting there is the hope that
`workshops could also be held in conjunction with the twice-yearly JWG meetings.
`ARVO maintains information on the Indo–US Collaborations at www.arvo.
`org/usindo. An inventory of collaborations can be found there as well as the names of
`researchers who have been involved with collaborations. n
`
`Dr. T.S. Rao, India Department of
`Biotechnology, and Dr. L. Ellwein, US
`National Eye Institute
`
`Workshop moderator Dr. D. Balasubramanian
`and speaker Dr. D. Beebe
`
`Participants question workshop speakers.
`
`www.arvo.org
`
`
`
`ARVONewS Summer 2007 
`
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`

`

` THE GLOBE
`
`Luncheon Spotlights
`Funding
`The ARVO International Advocacy
`
`Subcommittee hosted a luncheon at
`the 2007 ARVO Annual Meeting that
`featured a discussion on biomedical
`research funding with leaders from the
`ARVO International Chapter Affiliates
`in Argentina, Brazil and Israel. Each
`Chapter spoke to the 3 attendees about
`the manner and level at which govern-
`ments and private industry fund bio-
`medical research in their countries. The
`presentations were followed by a discus-
`sion on developing advocacy resources
`and tools for ARVO international
`members to obtain more research funding
`at the local level, as well as opportunities
`to learn more about raising funds from
`private industry.
`The ARVO International Advocacy
`Subcommittee is a subcommittee of
`the Advocacy Committee. It provides
`guidance and assistance to ARVO
`international members as they work
`to increase research funding in their
`countries. n
`
`Angela Suburo, MD, PhD from the Asociación
`de Investigación en Visión y Oftalmologia
`(AIVO) leads a discussion on support for
`biomedical research funding in Argentina.
`
`6
`
`ARVONewS Summer 2007
`
`
`
`First ARVO International Chapter Affiliate
`Council Convenes
`The first meeting of the ARVO International Chapter Affiliate Council
`
`took place at the 2007 Annual Meeting in Fort Lauderdale. The Council
`consists of officers from each of the International Chapter Affiliates, as well
`as past and present trustees from the ARVO Board. Their charge is to work
`with ARVO international members to recommend strategies and policies
`for increasing available funding opportunities for vision researchers outside
`the US; developing and promoting education programs at the local level;
`increasing travel grant opportunities for young researchers outside the US to
`attend ARVO; and promoting vision research around the world. n
`
`2007-2008 ARVO International Chapter Affiliate Council Members (front row,
`from left): Lori Methia and Ruth Rosenstein, MD; (back row, from left) Jacob Pe’er,
`MD; Janetha Pena, MD, PhD; Robert Barlow, PhD; Juan Gallo, MD; Luis Politi, PhD;
`Mario Guido, PhD; and Nora Rotstein, PhD
`
`2007 ARVO International Chapter Affiliates
`Travel Grant Recipients
`Each year, the ARVO International Chapter Affiliate Travel Grant
`
`recipients are selected by the organizations in the ARVO International
`Chapter Affiliates Program. Individuals interested in applying should contact
`the ARVO International Chapter Affiliate directly for application instruc-
`tions and deadlines. Visit the ARVO Chapter Affiliate Web page at www.
`arvo.org/affiliates to learn more. n
`
`Left: 2007 Israel Chapter
`Affiliate Ohad Shaham, Tel Aviv
`University; right: 2007 Argentina
`Chapter Affiliate Pablo Alejandro,
`Barrionuevo Universidad Nacional
`de Tucumán. Not pictured: 2007
`Brazil Chapter Affiliate Mirella
`Gualtieri, University of Sao Paulo;
`2007 Brazil Chapter Affiliate
`Eneida Mastrantonio, Federal
`University Uberlandia; and 2007
`Argentina Chapter Affiliate Ana Vanessa Torbidoni, Universidad Austral.
`www.arvo.org
`
`Mylan Exhibit 1059
`Mylan v. Regeneron, IPR2021-00880
`Page 6
`
`

`

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`
`International Trade Center, 175 Sarasota Center Boulevard, Sarasota FL 34240-9258 USA
`(cid:52)(cid:69)(cid:76)(cid:26)(cid:0)(cid:25)(cid:20)(cid:17)(cid:13)(cid:19)(cid:23)(cid:17)(cid:13)(cid:17)(cid:16)(cid:16)(cid:19)(cid:0)(cid:115)(cid:0)(cid:38)(cid:65)(cid:88)(cid:26)(cid:0)(cid:25)(cid:20)(cid:17)(cid:13)(cid:19)(cid:23)(cid:23)(cid:13)(cid:21)(cid:20)(cid:18)(cid:24)(cid:0)(cid:115)(cid:0)(cid:37)(cid:13)(cid:77)(cid:65)(cid:73)(cid:76)(cid:26)(cid:0)(cid:83)(cid:65)(cid:76)(cid:69)(cid:83)(cid:32)(cid:87)(cid:80)(cid:73)(cid:73)(cid:78)(cid:67)(cid:14)(cid:67)(cid:79)(cid:77)(cid:0)(cid:115)(cid:0)(cid:41)(cid:78)(cid:84)(cid:69)(cid:82)(cid:78)(cid:69)(cid:84)(cid:26)(cid:0)www.wpiinc.com/injection
`
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`

`ARVO ANNUAL MEETING
`
`Symposia
`Sunday April 27, 2008
`Molecules to Machines: Innovations in Restoring Vision
`Organizing Sections: RE, VI, VN, RC
`Organizers: Joseph Carroll, Maureen McCall, Ron Adelman, and Michael Boulton
`The human visual system is extremely susceptible to disease and damage; degeneration
`and damage occur in response to a variety of environmental and genetic insults.
`Unfortunately, in many cases the result is severe vision loss or even blindness. As
`researchers have begun to identify the specific disease mechanisms, it has become
`possible to design therapeutic strategies to intervene and restore vision. This symposium
`will feature five international leaders in their respective fields who will openly discuss the
`successes, failures, and future prospects of restorative therapies.
`
`Innovative Strategies for Eye Development and Regeneration in Non-Mammalian Models
`Organizing Sections: CO, GL, LE
`Organizers: Judith West-Mays and Michael Robinson
`This symposium will highlight recent progress in the genetic and molecular aspects of eye
`development and regeneration through the use of innovative (non-mammalian) animal
`models. Models to be discussed include invertebrates, fish, amphibians, and birds, and
`multiple ocular tissues will be considered, including the lens, retina, cornea, and anterior
`chamber. The main focus will be to demonstrate that these innovative animal models,
`including Drosophila, zebrafish, and amphibians, offer quick and easily manipulated
`strategies for understanding the genetics of eye development and regeneration and
`have provided many lessons that have been applied to human ocular development and
`disease.
`
`Nanomedicine Applications in Ophthalmology
`Organizing Sections: BI, CO, GL, RC
`Organizers: Michael Boulton and Robert Ritch
`Nanomedicine offers a new and important tool in the diagnosis and treatment of ocular
`diseases. Exciting new developments in the field of nanomedicine are now being realized
`and are being translated into diagnosis, treatment, and prevention of a variety of ocular
`conditions. This symposium will feature six international experts in the exploitation of
`nanomedicine who will review the state-of-the-art and current strategies being developed
`to combat ocular disease. The speakers will evaluate advantages and limitations of
`current nanomedicine and discuss future prospects.
`
`Ocular Biomechanics
`Organizing Sections: GL, EY, LE, CO, AP
`Organizer: S. Claude Burgoyne, Ross Ethier, and Crawford Downs
`This symposium will summarize the current state of knowledge regarding the role of
`biomechanics in the physiology and pathophysiology of the ocular tissues and suggest
`new directions for this field to explore. The biomechanics of seven ocular tissues will be
`discussed. Three broad areas will be addressed: What is the current state of knowledge
`regarding the biomechanics of their tissue? What needs to be done next to advance the
`science in their field? What are the important clinical implications and opportunities for
`translation? n
`
`Scientific Sessions Expanded in 2008
`In response to feedback from members, additional paper sessions will be offered at the
`
`2008 Annual Meeting for ARVO’s three largest sections — Cornea, Glaucoma and
`Retina. In addition, requests from members for expanded viewing time for posters has
`prompted the Board of Trustees to extend the Poster Session hours on Sunday through
`Wednesday. Posters will be available for viewing each day until 7:00 pm to allow maxi-
`mum access to the science. n
`ARVONewS Summer 2007
`
`8
`
`
`
`Eyes on Innovation
`Eyes on Innovation, the theme for the
`
`2008 ARVO Annual Meeting, April
`27–May 1 in Fort Lauderdale, Florida,
`will be a major forum
`for vision research-
`ers and practitioners
`to explore the latest
`innovative tech-
`niques, protocols, and
`tools in development
`and use by ophthal-
`mic researchers whose
`quest is to improve
`patient care and
`vision and to cure eye diseases. ARVO
`encourages the submission of abstracts to
`the 2008 Annual Meeting that showcase
`research innovations. Abstract submis-
`sions begin October 1, 2007 at www.arvo.
`org. (See the Call for Abstracts in the
`center of this newsletter for more informa-
`tion.) n
`
`The ARVO/Alcon
`
`Keynote Session,
`Sunday, April 27, 2008,
`will feature renowned
`author and inventor,
`Ray Kurzweil.
`Mr. Kurzweil is the
`author of The Age of
`Spiritual Machines, and
`Ray Kurzweil
`his latest book, The
`Singularity is Near, is a New York Times
`best seller. As one of the leading inventors
`of our time, Kurzweil was the principal
`developer of the first Charge Coupling
`Device (CCD) flat-bed scanner, the first
`omni-font optical character recognition,
`the first print-to-speech reading machine
`for the blind, the first text-to-speech
`synthesizer, the first music synthesizer
`capable of recreating the grand piano and
`other orchestral instruments, and the first
`commercially marketed large-vocabulary
`speech recognition.
`Kurzweil is the recipient of the MIT-
`Lemelson Prize, the world’s largest award
`for innovation, and in 1999 he received
`the National Medal of Technology, the
`nation’s highest honor in technology,
`from President Clinton in a White House
`ceremony. n
`
`www.arvo.org
`
`Mylan Exhibit 1059
`Mylan v. Regeneron, IPR2021-00880
`Page 8
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`

`

`ARVO ANNUAL MEETING
`
`ARVO Committee-Sponsored
`Workshops
`Animal Models in Ocular Drug Delivery
`Organized by the Animals in Research Committee
`
`From Bench to Bedside: Tips for Developing Your Drug or Medical
`Device
`Organized by the Commercial Relationships Committee
`
`Leadership in Science: Setting a Course for Women, Minorities, and
`Persons with Disabilities
`Organized by the Diversity Issues Committee
`
`The Ethics of Genetic Studies
`Organized by the Ethics and Regulations in Human Research Committee
`
`Successful Transition From Degree to Independence in Scholarship,
`Research, and Practice — Identifying and Developing Skills That
`Can Shape Your Career
`Organized by the Members-in-Training Committee n
`
`ARVO Education Co