`WIT. Kti barb!)
`DATE 3-2'l-2)--
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`FILE 'HOME' ENTERED AT 13:43:48 ON 18 MAR 2022
`CHARGED To COST=OFF
`
`> set account
`
`ENTER COST CENTER (NONE):0224-0002 BAJ
`
`Mylan Exhibit 1118
`Mylan v. Regeneron, IPR2021-00881
`Page 1
`
`
`
`COST CENTER SETTING WILL TAKE EFFECT WITH THE NEXT SUCCESSFUL FILE COMMAND
`SET COMMAND COMPLETED
`
`> file registry
`
`COST IN U.S. DOLLARS
`
`FULL ESTIMATED COST
`
`SINCE FILE
`ENTRY
`0.48
`
`TOTAL
`SESSION
`0.48
`
`FILE 'REGISTRY' ENTERED AT 13:45:11 ON 18 MAR 2022
`USE IS SUBJECT TO THE TERMS OF YOUR STN CUSTOMER AGREEMENT.
`COPYRIGHT (C) 2022 American Chemical Society (ACS)
`CHARGED TO C05T0224-0002 BAJ
`
`Property values tagged with IC are from the ZIC/VINITI data file
`provided by InfoChem.
`
`17 MAR 2022 HIGHEST RN 2762568-77-2
`STRUCTURE FILE UPDATES:
`DICTIONARY FILE UPDATES: 17 MAR 2022 HIGHEST RN 2762568-77-2
`
`CAS Information Use Policies apply and are available at:
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`http://www.cas.org/legal/infopolicy
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`TSCA Inventory information is current through February 2022.
`
`Please note that search-term pricing does apply when
`conducting SmartSELECT searches.
`
`REGISTRY includes numerically searchable data for experimental and
`predicted properties as well as tags indicating availability of
`experimental property data in the original document. For information
`on property searching in REGISTRY, refer to:
`
`http://www.cas . org/training/stn/database-specific
`
`e aflibercept/cn
`
`El
`E2
`E3
`E4
`ES
`E6
`E7
`ES
`E9
`E10
`Ell
`E12
`
`AFLEX-BOND AG 9100/CN
`1
`AFLI/CN
`1
`1 --> AFLIBERCEPT/CN
`1
`AFLIBERCEPT (SYNTHETIC PRECURSOR)/CN
`1
`AFLIBERCEPT ISO-OSMOTIC OPHTHALMIC/CN
`1
`AFLIBERCEPT-ZIV/CN
`1
`AFLII/CN
`1.
`AFLIII/CN
`1
`AFLIX/CN
`1
`AFLOBEN/CN
`1
`AFLOC HIS 1613/CN
`1
`AFLODAC/CN
`
`=> 5 e3
`
`Ll
`
`1 AFLIBERCEPT/CN
`
`=> d 11 fide
`
`Ll
`RN
`ED
`CN
`
`ANSWER 1 OF 1 REGISTRY COPYRIGHT 2022 ACS on STN
`862111-32-8 REGISTRY
`Entered STN: 30 Aug 2005
`Vascular endothelial growth factor receptor type VEGFR-1 (synthetic human
`immunoglobulin domain 2 fragment) fusion protein with vascular endothelial
`growth factor receptor type VEGFR-2 (synthetic human immunoglobulin domain
`3 fragment) fusion protein with immunoglobulin G1 (synthetic Fc fragment),
`dimer (CA INDEX NAME)
`OTHER NAMES:
`CN
`Afibercept
`
`Mylan Exhibit 1118
`Mylan v. Regeneron, IPR2021-00881
`Page 2
`
`
`
`ON Aflibercept
`ON
`Aflibercept iso-osmotic ophthalmic
`CN
`AVE 0005
`CN
`Eylea
`ON
`VEGF trap
`ON
`VEGF Trap R1R2
`CN
`VEGF Trap-Eye
`FS
`PROTEIN SEQUENCE
`DR
`924289-53-2
`MF
`Unspecified
`CI
`COM, MAN
`SR
`CAS Client Services
`LC
`STN Files:
`ADISINSIGHT, CA, CAPLUS, cASFORMULTNS, CHENcATS, CHEMLIST,
`ENBASE, IMSRESEARCH, IPA, MEDLINE, TOXCENTER, USPAT2, USPATFULL
`DT.CA CAplus document type: Conference; Dissertation; Journal; Patent;
`Preprint
`Roles from patents: ANST (Analytical study); BIOL (Biological study);
`NANO (Nanomaterial); PREP (Preparation); PROC (Process); PAP
`(Properties); PRPH (Prophetic); PACT (Reactant or reagent); USES (Uses)
`RLD.P Roles for non-specific derivatives from patents: BIOL (Biological
`study); PREP (Preparation); PRP (Properties); USES (Uses)
`RL.NP Roles from non-patents: ANST (Analytical study); BIOL (Biological
`study); OCCU (Occurrence); PRP (Properties); USES (Uses)
`
`RL.P
`
`*** STRUCTURE DIAGRAM IS NOT AVAILABLE ***
`*** USE 'SQD' OR 'SQIDE' FORMATS TO DISPLAY SEQUENCE ***
`1717 REFERENCES IN FILE CA (1907 TO DATE)
`32 REFERENCES TO NON-SPECIFIC DERIVATIVES IN FILE CA
`1854 REFERENCES IN FILE CAPLUS (1907 TO DATE)
`
`=> logoff
`
`ALL L# QUERIES AND ANSWER SETS ARE DELETED AT LOGOFF
`LOGOFF? (Y)/N/HOLD:y
`
`COST IN U.S. DOLLARS
`
`FULL ESTIMATED COST
`
`SINCE FILE
`ENTRY
`28.45
`
`TOTAL
`SESSION
`28.93
`
`STN INTERNATIONAL LOGOFF AT 13:46:57 ON 18 MAR 2022
`
`Mylan Exhibit 1118
`Mylan v. Regeneron, IPR2021-00881
`Page 3
`
`