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12/17/21, 6:41 PM
`
`Blindness and vision impairment
`
`@y WorldHealth
`WSsOrganization
`
`
`
`Blindness and vision
`impairment
`
`14 October 2021
`
`.
`
`.
`
`~
`
`| K
`
`getell
`
`ey facts
`
`¢ Globally, at least 2.2 billion people have a near or distance vision impairment.In at least 1 billion — or
`almost half — of these cases, vision impairment could have been prevented or has yet to be addressed.
`¢ The leading causes of vision impairment and blindness are uncorrected refractive errors and
`cataracts.
`
`¢ The majority of people with vision impairment and blindnessare over the age of 50 years; however,
`vision loss can affect people of all ages.
`
`¢ Vision impairment poses an enormousglobal financial burden with the annual global costs of
`productivity losses associated with vision impairment from uncorrected myopia and presbyopia alone
`estimated to be US$ 244 billion and US$ 25.4 billion.
`
`Definitions
`
`The International Classification of Diseases 11 (2018) classifies vision impairment into two groups,
`distance and near presenting vision impairment.
`; ee
`Distance vision impairment:
`
`Exhibit 2269
`Page 01 of 05
`https:/Avww.who.int/news-room/fact-sheets/detail/blindness-and-visual-impairment
`
`
`
`Mylan v. Regeneron
`IPR2021-00881
`U.S. Pat. 9,254,338
`Exhibit 2269
`
`1/5
`
`Exhibit 2269
`Page 01 of 05
`
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`Page 02 of 05
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`Exhibit 2269
`Page 03 of 05
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`Exhibit 2269
`Page 05 of 05
`
`

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