Lucian V. Del Priore, MD, PhD, MS, MA (Honorary)
`
`Robert R. Young Professor and Chair
`Department of Ophthalmology
`Yale Eye Center
`40 Temple St., Suite 1B
`New Haven, CT 06510
`Cell 908 625 0395
`ldelpriore@yahoo.com
`
`Robert R. Young Professor and Chair, Department of Ophthalmology and Visual
`Science, Yale Eye Center, Yale University School of Medicine, New Haven, CT, July 2016 to
`present. Chief of Ophthalmology, Yale New Haven Hospital, New Haven, CT, July 2016 to
`present.
`
`Pierre G. Jenkins Professor and Chairman, Department of Ophthalmology,
`Director of the Albert Florens Storm Eye Institute; Professor, Department of Regenerative
`Medicine, Medical University of South Carolina, Charleston, SC, October 2011 to July 2016.
`
`Professor of Clinical Ophthalmology, Department of Ophthalmology and Robert L.
`Burch III Scholar, College of Physicians and Surgeons, Columbia University, New York, NY,
`January 1, 2006 to September 30, 2011; Associate Professor of Ophthalmology and Robert L.
`Burch III Scholar, September 1, 2000 to December 2005. Member, Stem Cell Consortium,
`Columbia University May 2009 – Sept 30, 2011.
`
`Chief of Vitreoretinal Surgery, Associate Professor of Ophthalmology, Associate
`Professor of Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, NJ,
`August 1998 to August 2000.
`
`Assistant Professor of Ophthalmology and Visual Sciences (July 1991 to 1998),
`Assistant Professor of Biochemistry and Molecular Biophysics (July 1991 to 1998),
`Associate Professor of Ophthalmology and Visual Sciences (July 1998 to December 1999),
`Washington University School of Medicine, St. Louis, MO.
`
`Instructor in Ophthalmology, July 1989 to June 1991, The Wilmer Eye Institute, The
`Johns Hopkins Hospital, Baltimore, MD and Attending Ophthalmologist, July 1989 to June
`1991, Washington Eye Physicians and Surgeons, 5454 Wisconsin Avenue, Suite 950, Chevy
`Chase, Maryland 20815.
`
`COMMITTEE EXPERIENCE
`
`Finance Committee, Yale University School of Medicine, July 2016 – present
`
`Medical Executive Committee, Yale New Haven Hospital, July 2016- present
`
`Exhibit 2081
`Page 01 of 58
`
`

`

`Del Priore: curriculum vitae Page 2
`
`Steering Committee, Yale Medicine Access and Care Center, Yale University School of
`Medicine, July 2019-present
`
`Member of the Board, University Medical Associates, Medical University of South
`Carolina, October 2011-2012. Member of the physician practice plan board at MUSC.
`
`Faculty Compensation Committee, Medical University of South Carolina, October
`2011-2012. Committee was responsible for recommending changes in the structure of faculty
`compensation at MUSC.
`
`Access Management Committee, Medical University of South Carolina, October 2012-
`present.
`
`Medical Executive Committee, Medical University of South Carolina, October 2011-
`
`2012.
`
`Practice Plan for Department of Ophthalmology, Physician Representative for
`Clinical Operations, Columbia University College of Physicians and Surgeons, September 2006
`-2010. I worked with the Chairman of the Department for Ophthalmology, departmental
`administrator and the practice manager to restructure departmental clinical operations. I was
`involved in improving efficiency of clinical operations and collections, and all aspects of office,
`including management including patient flow to operations in medical records, photography,
`technicians, front and back office staff.
`
`Executive Committee of the Faculty Council, Columbia University College of
`Physicians and Surgeons, September 2004 to September 2011.
`
`Voting Member of the Faculty Council, Columbia University College of Physicians
`and Surgeons, July 1, 2004 to September 2011.
`
`Clinical Trials Advisory Committee, Columbia University, July 2005 to September
`
`2011.
`
`Board of Directors, Barnes Retina Institute, Barnes Hospital, July 1, 1995 to July 1998.
`Responsible for management of 11 physician joint venture composed of 4 full-time faculty
`members of the Department of Ophthalmology and Visual Sciences at Washington University
`and 7 vitreoretinal surgeons on the part-time staff of Barnes Hospital.
`
`Member, Faculty Compensation Committee, Department of Ophthalmology and
`Visual Sciences, Washington University School of Medicine, February 1995 to January 1997.
`Responsible for restructuring the faculty compensation plan for full-time members of the
`Department of Ophthalmology based on principles of strong faculty incentives in a time of
`decreasing physician reimbursement.
`
`Member, Executive Clinical Faculty, Department of Ophthalmology and Visual
`Sciences, Washington University School of Medicine, 1997-1998.
`
`Exhibit 2081
`Page 02 of 58
`
`

`

`Del Priore: curriculum vitae Page 3
`
`Co-Director, Vitreoretinal Surgery Fellowship Program, Washington University
`School of Medicine, July 1991 to July 1998.
`
`Quality Assurance Subcommittee Member, Barnes Hospital, Fall 1994 to Fall 1996.
`Responsible for quality assurance/outcome analysis within the Department of Ophthalmology.
`
`CLINICAL TRAINING
`
`Fellow in Vitreoretinal Surgery and Assistant Surgeon, 1988 and 1989, Preceptors:
`Ronald G. Michels, MD, Bert M. Glaser, MD, Serge de Bustros, MD; The Wilmer Eye Institute,
`The Johns Hopkins Hospital, Baltimore, MD
`
`Fellow in Glaucoma, 1987 and 1988, Preceptors: Harry A. Quigley, MD, Irv P. Pollack,
`MD; The Wilmer Eye Institute
`
`Resident in Ophthalmology, July 1984 to June 1987, The Wilmer Eye Institute
`
`Intern in Internal Medicine, July 1983 to June 1984, Greater Baltimore Medical Center,
`Baltimore, MD
`
`EDUCATION
`
`MA (M.A. honorary, privatim), February 2017, Yale University, New Haven, CT
`
`PhD in Physics, August 1984, Cornell University, Ithaca, NY. Thesis advisor: Dr. Aaron
`Lewis. The Molecular Basis of Visual Transduction in Vertebrate Rod Photoreceptors.
`
`MD with Distinction in Research, June 1982, The University of Rochester School of
`Medicine and Dentistry, Rochester, NY
`
`MS in Physics, August 1977, Cornell University
`
`BS summa cum laude, June 1975 (Major: Physics; Minor: Mathematics), Cooper Union
`for the Advancement of Science and Art, New York, NY
`
`HOSPITAL PRIVILEGES AND APPOINTMENTS
`
`Attending Ophthalmologist, July 5, 2016 to present, Yale University School of
`Medicine, New Haven, CT
`
`Attending Ophthalmologist, October 1, 2011 to July 2016, Medical University of South
`Carolina, Charleston, SC
`
`Exhibit 2081
`Page 03 of 58
`
`

`

`Del Priore: curriculum vitae Page 4
`
`Attending Ophthalmologist, August 1, 2000 to September 30, 2011, New York
`Presbyterian Hospital, New York, NY
`
`Attending Ophthalmologist, August 1, 1998 to August 1, 2001, University Hospital,
`Newark, NJ
`
`Attending Ophthalmologist, July 1, 1991 to July 1998, Barnes Hospital at Washington
`University Medical Center, Barnes West County Hospital, Saint Louis Children's Hospital, The
`Jewish Hospital of Saint Louis, Veterans Administration Hospital, Saint Louis, MO
`
`Attending Surgeon, July 1989 to June 1991, The Wilmer Eye Institute, The Johns
`Hopkins Hospital, Baltimore, MD and Washington Hospital Center, Washington, D.C.
`
`HONORS AND AWARDS
`
`Inducted into the Retina Hall of Fame, American Society of Retinal Specialists,
`December 2021
`
`New York Ophthalmological Society, inducted at the Union Club, New York, NY,
`April 2019.
`
`Connecticut Magazine Best Doctors, included within a guide published by Castle
`Connolly Medical Limited, Second Edition, 2018-2019.
`
`American Academy of Ophthalmology, Life Fellow and Member, received August
`
`2018
`
`MA (M.A. honorary, privatim), February 2017, Yale University, New Haven, CT
`
`American Academy of Ophthalmology Senior Achievement Award, June 2016.
`Received in recognition of commitment to advancing the profession.
`
`America’s Top Doctors, included within a guide published by Castle Connolly Medical
`Limited, Second Edition, 2002-2019.
`
`Distinguished Alumnus Award, The Wilmer Ophthalmological Institute, June 8, 2012.
`Received in recognition of outstanding contribution to ophthalmology as a Wilmer Graduate.
`
`New York Super Doctors, supplement to the New York Times, 2008, 2009, 2010.
`
`Senior Honor Award, The American Society of Retina Specialists, New York, New
`York September 2009.
`
`Fellow of the Association for Research in Vision and Ophthalmology, ARVO Fellow
`Silver level, inducted in the Class of 2009.
`
`Exhibit 2081
`Page 04 of 58
`
`

`

`New York’s Top Doctors, New York magazine, 2002, 2003, 2004, 2005, 2006, 2007,
`
`2008.
`
`Del Priore: curriculum vitae Page 5
`
`Best Doctors in America, included in 2005-2006 database.
`
`Honor Award, The American Society of Retina Specialists, San Diego, CA 2004.
`
`Honor Award, The Vitreous Society, awarded 2002.
`
`Lew R. Wasserman Award, Research to Prevent Blindness, June 1999
`
`Teacher of the Year Award, Department of Ophthalmology, the University of Medicine
`and Dentistry of New Jersey, June 1999
`
`Honor Award, American Academy of Ophthalmology, awarded 1994
`
`Heed/Knapp Foundation Fellow, July 1988 to June 1989
`
`Heed Foundation Fellow, July 1987 to June 1988
`
`Medical Scientist Training Program Fellow, September 1977 to November 1979, The
`University of Rochester
`
`Biophysics Fellow, September 1976 to August 1977, Cornell University
`
`Sigma Pi Sigma, elected in l974
`
`Board of Regents Scholar, New York State, September 1971 to June 1975
`
`TEACHING EXPERIENCE (non clinical)
`
`Instructor in Bioengineering, January 1980 to August 1980, The University of Utah,
`Salt Lake City, Utah
`
`Teaching Assistant in Physiology, Fall 1979, Cornell University
`
`Lecturer in Physics, Summer 1977 and 1978, Cornell University
`
`Laboratory Instructor in Physics, Summer 1976, Cornell University
`
`Teaching Assistant in Physics, September 1975 to June 1977, Cornell University
`
`PROFESSIONAL MEMBERSHIPS
`American Association for the Advancement of Science
`American Academy of Ophthalmology
`
`Exhibit 2081
`Page 05 of 58
`
`

`

`Del Priore: curriculum vitae Page 6
`
`Association for Research in Vision and Ophthalmology
`American Medical Association
`American Society of Retinal Specialists
`International Society for Eye Research
`The Retina Society
`The Macula Society
`Research to Prevent Blindness
`The European Retina Society of Retina Specialists
`South Carolina Medical Association
`
`BOARD CERTIFICATION
`Diplomate, American Board of Ophthalmology, certified May 16, 1989
`Diplomate, National Board of Medical Examiners, certified November 1984
`
`MEDICAL LICENSURE
`
`STATE
`South Carolina
`New York
`
`New Jersey
`
`Florida
`
`Maryland
`District of Columbia
`Missouri
`Illinois
`
`
`
`LICENSE #
`AL34173
`182408
`
`MA 067450
`ME-0066474
`D34798
`17908
`MD R2P26
`036-092682
`
`
`
`
`STATUS
`ISSUED
`10/18/2011 ACTIVE
`6/26/90
`ACTIVE
`7/1/98
`ACTIVE
`12/9/95
`ACTIVE
`3/3/87
`INACTIVE
`6/28/89
`INACTIVE
`4/26/91
`INACTIVE
`8/1/96
`INACTIVE
`
`MISCELLANOUS LICENSE NUMBERS
`UPIN number
`B 70141
`DEA
`BD 1758785
`NPI
`
`1790702769
`
`PATENTS:
`
`Mark Fields, Huey Cai, Lucian V Del Priore, Denton Hoyer: “Compounds and Methods for
`Treating or Preventing Retinal Degenerations, Including Age-Related Macular Degeneration”
`New U.S. Provisional Patent Application No. 62/614,757 filed January 8, 2018. Yale Ref.: OCR
`7229. Our Ref.: 047162-7149P1(00643)
`
`SCIENTIFIC ADVISORY BOARDS AND FDA PANELS
`
`Consultant - Astellas Institute for Regenerative Medicine, 2017-2021
`
`Scientific advisory board: LambdaVision, Farmington, CT
`
`Scientific advisory board, Tissue Regeneration Sciences, New York, NY
`
`Exhibit 2081
`Page 06 of 58
`
`

`

`Del Priore: curriculum vitae Page 7
`
`Consultant - CavtheRx, New Haven, CT
`
`Medical and Scientific Advisor, Company Co-founder, Seeing Medicines, based out of
`Rochester, MN
`
`Member, FDA Panel September 2017, Ad hoc member for FDA Panel on Ophthalmologic
`Products
`
`Chairman, Regenerative Medicine and Cell Therapy Program (formerly Cell Based Therapy
`Program), July 1, 2005 - forward. Member, Scientific Advisory Board, Foundation Fighting
`Blindness, Owings Mills, Maryland
`
`National Scientific Advisory Council (NSAC) Member, 2012 – forward. American Federation
`for Aging Research (AFAR), 55 West 39th Street, 16th Floor, New York, NY 10018
`
`Scientific Advisory Board, Advanced Cell Technology, Boston, Mass. 2012 – 2016, Responsible
`for overseeing safety aspects of a clinical trial for the treatment of advanced Stargardt’s disease
`with transplantation of stem cells differentiated along an RPE lineage
`
`Member of the International Scientific Committee, August 2007 – 2011, Fondazione Retina 3000
`(medical foundation), Centro Oftalmologico, Milano, Italia
`
`PERSONAL
`Fluent in Italian; can converse in Spanish.
`Hobbies: Tennis, PADI certified scuba diving, snorkeling, skiing.
`
`EDITORIAL BOARDS
`
`1. Journal of Ophthalmology, 2008-forward
`
`2. Journal of Stem Cell Research and Transplantation, Editorial Board Member
`
`3. Open Access Journal of Ophthalmology, MedWin Publishers, Associate Editor
`
`PEER REVIEWER FOR THE FOLLOWING JOURNALS (within last 24 months)
`Nature Medicine
`American Journal of Ophthalmology
`Archives of Ophthalmology
`Current Eye Research
`Experimental Eye Research
`Investigative Ophthalmology and Visual Sciences
`Ophthalmology
`Retina
`
`Exhibit 2081
`Page 07 of 58
`
`

`

`Del Priore: curriculum vitae Page 8
`
`MISCELLANEOUS
`
`1.
`
`2.
`
`3.
`
`4.
`
`5.
`
`6.
`
`7.
`
`8.
`
`9.
`
`10.
`
`11.
`
`12.
`
`13.
`
`Moderator, Session on RPE Transplantation, Meeting of the Association for
`Research in Vision and Ophthalmology, Sarasota, FL, May 1994.
`
`Moderator, Session on Submacular Surgery, Meeting of the Association for
`Research in Vision and Ophthalmology, Sarasota, FL, May 1995.
`
`Moderator, ARVO Press Forum on Gene Manipulation/Transplantation in the Eye-
`- A Site for Sore Eyes, Meeting of the Association for Research in Vision and
`Ophthalmology, Fort Lauderdale, FL, May 1997.
`
`Organizer and Member of the Scientific Committee, International Conference on
`New Developments in the Treatment of Age-related Macular Degeneration,
`Gardonne, Italy, June 1997.
`
`Moderator, Platform session on Retinal and RPE Transplantation, Meeting of the
`Association for Research in Vision and Ophthalmology, Sarasota, FL, May 1998.
`
`Member of the National Scientific Advisory Council, American Federation for
`Aging Research, 1414 Avenue of the Americas, New York, NY 10019, November
`1998 to present.
`
`Member of the Program Planning Committee (Retina), Association for Research in
`Vision and Ophthalmology, 1999-2001.
`
`Ad hoc member of the Vision C Study Section, National Institutes of Health,
`Washington DC, October 11-12, 1999.
`
`Ad hoc member of the Vision C Study Section, National Institutes of Health,
`Washington, DC, February 2000.
`
`Moderator, Platform session on Vitreoretinal Experimental Studies, Retina Society
`meeting, Coral Gables, Florida, December 2000.
`
`Moderator, Platform session on Retinal and RPE Transplantation, Meeting of the
`Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, May
`2001.
`
`Organizer and Member of the Scientific Committee, Second International
`Conference on New Developments in the Treatment of Age-related Macular
`Degeneration, Gubbio, Italy, June 2001.
`
`Moderator, Platform session on Retinal and RPE Transplantation, Meeting of the
`Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, May
`
`Exhibit 2081
`Page 08 of 58
`
`

`

`Del Priore: curriculum vitae Page 9
`
`2002.
`
`14.
`
`15.
`
`16.
`
`17.
`
`18.
`
`Moderator, Symposium on The Role of Bruch’s Membrane in the Development of
`Age-related Macular Degeneration, Meeting of the Association for Research in
`Vision and Ophthalmology, Ft. Lauderdale, FL, May 2002.
`
`Member, Liaison Committee, Foundation Fighting Blindness Pathophysiology
`facility, December 2002 forward.
`
`Ad hoc member of the Member of Special Emphasis Panel, National Eye Institute,
`EEY1 VSN (01), Bethesda, Maryland, July 26, 2006.
`
`Moderator of Special Interest Group (SIG) Enzymatic Vitreopharmacolysis in
`Vitreoretinal Disease. Association for Research in Vision and Ophthalmology,
`April 2008, Fort Lauderdale, FL.
`
`Moderator, Special Interest Group on Maculoplasty, Association for Research in
`Vision and Ophthalmology, April 2008, Fort Lauderdale, FL.
`
`RESEARCH GRANTS
`
`1. Diabetes Research Training Grant.
`Source: NIH P60 DK20579 Principal Investigator - Dr. David Kipnis.
`From December 1, 1992 to November 30, 1997.
`Role on Project - Consulting Ophthalmologist. 9% effort.
`
`2. Collaborative Ocular Melanoma Study.
`Funding Source: NIH Project # 5 U10 EY06280-11, Principal Investigator/Director - Barbara
`Hawkins, PhD, Chairman- Stuart Fine, MD.
`Annual Direct Costs: $4,900 (Washington University component).
`From: 9/30/85-7/31/00.
`Role: Principal Investigator at Washington University School of Medicine (part of multi-
`centered clinical trial). Percent Effort: <2%.
`
`3. Transplantation of Retinal Pigment Epithelium in Age-related Macular Degeneration.
`Funding Source: The Kemper Foundation, Kansas City, MO.
`Total award: $50,000.
`From: April 1, 1997 to August 1, 1998.
`Role: Principal Investigator.
`
`4. Transplantation of Fetal Porcine Retinal Pigment Epithelium into the Adult Porcine Eye.
`Funding Source: Diacrin Inc
`Total award: $80,000.
`From: December 1, 1997 to August 1, 1998.
`Role: Principal Investigator.
`
`Exhibit 2081
`Page 09 of 58
`
`

`

`Del Priore: curriculum vitae Page 10
`
`5. Individual National Research Service Award.
`Funding Source: National Institutes of Health.
`Total award: $29,004. Effort 9%.
`From: July 1987 to June 1988.
`Role: Post-doctoral Fellow.
`
`6. Transplantation of Pig Retinal Pigment Epithelium
`Funding Source American Federation for Aging Research
`Total award: $25,000.
`From: July 1, 1993 to June 30, 1994.
`Role: Principal Investigator.
`
`7. Laser-Induced Biochemistry of Retinal Pigment Epithelium.
`Funding Source: Diabetes Research Training Center, Washington University.
`Total award: $20,000.
`From: December 1, 1993 to November 30, 1994.
`Role: Principal Investigator.
`
`8. Growth Factor Release after Laser Photocoagulation of the Retinal Pigment Epithelium.
`Funding Source: American Diabetes Association.
`Total award: $100,000.
`From: January 1, 1995 to June 30, 1997.
`Role: Principal Investigator.
`
`9. Binding of Human Retinal Pigment Epithelium to Normal and Diseased Areas of Bruch’s
`Membrane in Organ Culture.
`Funding Source: RP Foundation Fighting Blindness.
`Total award: $240,000.
`From: From January 1, 1996 to December 31, 1998.
`Role: Principal Investigator.
`
`10. Role of Bruch’s Membrane in Age-Related Macular Degeneration.
`Funding Source: New Jersey Fund for the Blind.
`Total award: $2500.
`From: October 1, 1999 to October 1, 2000.
`Role: Principal Investigator.
`
`11. Lew R. Wasserman Award
`Funding Source: Research to Prevent Blindness, New York, NY
`Total award: $55,000.
`From: June 16, 1999 to August 2000.
`Role: Principal Investigator.
`
`12. Transplantation of Retinal Pigment Epithelial Cells May Prevent Atrophy of the
`Choriocapillaris and Overlying Retina. Fight for Sight postdoctoral fellowship award on behalf
`of Dr. Takehiko Suzuki.
`Total award: $14,000.
`
`Exhibit 2081
`Page 10 of 58
`
`

`

`Del Priore: curriculum vitae Page 11
`
`From: July 1, 1999 to June 30, 2000.
`Role: Supervised Postdoctoral Fellow.
`
`13. Postdoctoral Fellowship supplement.
`Funding Source: UMDNJ Foundation
`Total award: $5,000.
`From: July 1, 1999 to June 30, 2000.
`Role: Supervised Postdoctoral Fellow.
`
`14. Binding of Human Retinal Pigment Epithelium to Normal and Diseased Areas of Bruch’s
`Membrane in Organ Culture.
`Source: RP Foundation Fighting Blindness.
`From: July 1, 1999 - June 30, 2001.
`Total award: $194,316.
`Role: Principal Investigator.
`15. Effect of Extracellular Matrix Ligands on RPE Attachment to Bruch’s Membrane
`Funding Source: American Health Assistance Foundation.
`Total award: $137,000
`From: April 1, 1999 to March 30, 2002.
`Role: Principal Investigator.
`
`16. Transplantation of Retinal Pigment Epithelium.
`Source: R01 from the National Eye Institute, National Institute of Health.
`Total award: $411,228.63 (direct costs) for 1/1/94-12/31/96; $600,000 (approximate direct costs)
`for 1/1/97 to12/31/01: Effort: 40%.
`From: January 1, 1994 to December 31, 2001, application in revision.
`Role: Principal Investigator.
`
`17. Xenotransplantation of Fetal Porcine RPE into the Rabbit Eye.
`Funding Source: Diacrin Inc., Charlestown, Massachusetts.
`Total award: $81,543.
`From: February 1, 2001 until December 31, 2002.
`Role: Principal Investigator.
`
`18. Greater NY Center for the Study of Retinal Degeneration: Columbia University Center
`Source: Foundation Fighting Blindness.
`From: July 1, 2001 - June 30, 2005.
`Total award: $1,085,584 for Modules X-XII; $425,627 for module X-XII.
`Role: Director, Columbia University Center
`Principal Investigator for Module X (Binding of Human RPE to Diseased Human
`Bruch’s Membrane in Organ Culture).
`
`19. Changes in Gene Expression of RPE Seeded onto AMD Bruch’s Membrane.
`Funding Source: The Macula Society.
`Total award: $10,000.
`From: January 1, 2002 forward.
`Role: Principal Investigator.
`
`Exhibit 2081
`Page 11 of 58
`
`

`

`Del Priore: curriculum vitae Page 12
`
`20. Unrestricted Funds to Support Eye Research
`Funding Source: Eye Surgery Fund, Columbia University.
`Total award: $140,000.
`From January 1, 2002 to December 2006.
`Role: Principal Investigator.
`
`21. Laser-induced and chemical rejuvenation of aged collagen
`Source: Hickey Family Foundation
`From: March 1, 2005 to February 28, 2008
`Direct Costs: $100,000 per year for 3 years
`Role: Principal Investigator
`Goals: To demonstrate that laser photocoagulation and chemical treatments can be used to
`reverse age-related changes in collagen the human eye, and that this will improve the behavior of
`retinal pigment epithelium in AMD.
`
`22. Stem Cell Transplantation for Retinal Degenerations
`Funding Source: The Macula Foundation
`Total Award: $25,000 per annum for 3 years
`From January 2006-December 2008
`Role: Principal Investigator
`
`23. Greater New York Center for Retinal Degenerative Disease
`Foundation Fighting Blindness, 11435 Cronhill Drive
`Owings Mills, MD 21117-2220
`Role: Principal Investigator, Columbia University component; Co-investigators at Columbia
`University: Rando Allikmets, PhD; Stephen Goff, PhD
`Center Coordinators at other sites:
`Marco A. Zarbin, MD, PhD, University of Medicine and Dentistry of New Jersey
`Ronald Carr, MD; New York University
`Total Amount: $1,683,223
`Dates: 07/01/2005-6/30/2010
`
`24. Embryonic Stem Cell Differentiation in Retinal and RPE Progenitors
`Source: Hickey Family Foundation
`From: March 1, 2008 to February 28, 2011
`Direct Costs: $161,238 for first year; $497,214 total for 3 years
`Role: Principal Investigator
`Goals: To induce the differentiation of embryonic stem cells (mouse and human) into
`photoreceptors and retinal epithelium prior to transplantation into animal models of age-related
`macular degeneration.
`
`25. Generation of a Murine Model of Geographic Atrophy and Its treatment with Embryonic
`Stem Cell Transplantation
`Source: Beckman Institute for Macular Research
`From: July 1, 2010 to June 30, 2011
`Direct Costs: $100,000
`
`Exhibit 2081
`Page 12 of 58
`
`

`

`Role: Principal Investigator. Co-investigators: Stephen Tsang, MD, PhD, Janet Sparrow, PhD, R
`Theodore Smith, MD
`Goals: To generate an animal model of geographic atrophy and treat this disorder with
`embryonic stem cells that are differentiated towards an RPE lineage.
`
`Del Priore: curriculum vitae Page 13
`
`26. Unrestricted Funds to Support Research in Age-related Macular Degeneration
`Funding Source: Robert L. Burch III Fund, Columbia University.
`Total award: $130,000.
`From January 1, 2002 to September 2011.
`Role: Principal Investigator.
`
`27. Greater New York Center for Retinal Degenerative Disease
`Foundation Fighting Blindness, 11435 Cronhill Drive
`Owings Mills, MD 21117-2220
`Role: Principal Investigator
`Total Amount: $1,500,000
`Dates: 07/01/2010-6/30/2015
`
`28. Research to Prevent Blindness
`New York, NY
`Role: Principal Investigator
`Total: $115,000 per year
`Dates: 7/1/11 to 6/30/16
`
`CLINICAL TRIALS:
`
`Second Sight Medical Products, study on implantation of the artificial retina in patient with
`severe retinitis pigmentosa.
`Role: Principal Investigator and Principal Surgeon
`Sponsor: Second Sight
`Purpose: Implanted an artificial retinal prosthesis into the eye of a patient with bare light
`perception vision from end stage retinitis pigmentosa.
`
`PUBLICATIONS
`
`1
`
`2
`
`3
`
`Del Priore LV, Doyle C, Andrade JD. Characterization of Vapor-deposited Silver Films
`Exhibiting Surface-enhanced Raman Scattering by Raman and X-ray Photoelectron
`Spectroscopy. Applied Spectroscopy 36:69-71, 1982.
`Del Priore LV, Lewis A. Calcium-dependent Activation and Deactivation of Rod Outer
`Segment Phosphodiesterase is Calmodulin-independent. Biochem Biophys Res Commun
`113:317- 324, 1983.
`Del Priore LV, Lewis A, Schaat KA. Membrane Structural Alterations in Malignant and
`Normal Avian Lymphocytes: A Raman Investigation. Membrane Biochemistry 5:97-107,
`1984.
`
`Exhibit 2081
`Page 13 of 58
`
`

`

`4
`
`5.
`
`6.
`
`7.
`
`8.
`
`9.
`
`10.
`
`11.
`
`12.
`
`13.
`
`14.
`
`15.
`
`16.
`
`17.
`
`18.
`
`19.
`
`20.
`
`21.
`
`22.
`
`23.
`
`Del Priore: curriculum vitae Page 14
`
`Del Priore LV, Lewis A. Vanadate, Tungstate and Molybdate Activate Rod Outer
`Segment Phosphodiesterase in the Dark. Biochem Biophysica Acta 845:81-85, 1985.
`Del Priore LV, Guyton DL. The Jackson Cross Cylinder: A Reappraisal. Ophthalmology
`93:1461-1465, 1986.
`Del Priore LV, Lewis A, Carley WW, Webb WW. Fluorescence Light Microscopy of F-
`Actin in Retinal Rods and Glial Cells. Inv Ophthalmol Vis Sci 8:633-639, 1987.
`Guyton DL, Del Priore LV. Letter to the Editor, The Jackson Cross Cylinder (Reply)
`Ophthalmology 94:893-894, 1987.
`Pollack IP, Robin AL, Streisfeld DL, Del Priore LV, et al. Neodymium:YAG Laser:
`Histopathology of Effects Upon Monkey Trabecular Meshwork and Role in the
`Treatment of Open-angle Glaucoma. In: Glaucoma Update III. Ed: G. K. Krieglstein,
`Springer-Verlag, Berlin Heidelberg (1987), p. 185-193.
`Lewis A, Del Priore LV. The Biophysics of Visual Photoreception. Physics Today 41:38-
`46, 1988.
`Del Priore LV, Robin AL, Pollack IP. Long-term Follow-up of Neodymium:YAG Laser
`Angle Surgery for Open-angle Glaucoma. Ophthalmology 95:277-281, 1988.
`Del Priore LV, Robin AL, Pollack IP. Neodymium:YAG versus Argon Laser Iridotomy
`for Pupillary Block Glaucoma. Ophthalmology 95:1207-1211, 1988.
`Del Priore LV, Glaser BM, Quigley HA, Dorman ME, Green WR. Morphology of Pig
`Retinal Pigment Epithelium Maintained in Organ Culture. Arch Ophthalmology
`106:1286-1290, 1988.
`Del Priore LV, Glaser BM, Quigley HA, Green WR. Response of the Retinal Pigment
`Epithelium to Laser Photocoagulation In Vitro. Arch Ophthalmology l07:119-122, l989.
`Del Priore LV, Michels RG, Nunez MA, Smiddy W, Glaser BM, de Bustros S.
`Intraocular Pressure Measurement after Pars Plana Vitrectomy. Ophthalmology 96:1353-
`1356, 1989.
`Del Priore LV, Miller NR. Trigeminal Schwannoma as a Cause of Chronic Isolated Sixth
`Nerve Palsy. Am J Ophthalmol 108:726-729,1989.
`Schwartz AL, Del Priore LV. The Evolving Role of Argon Laser Trabeculoplasty in
`Glaucoma. Ophthalmology Clinics of North America 4:827-838, 1991.
`Del Priore LV, Kaplan HJ, Silverman MS, Valentino T, Mason G, Hornbeck R.
`Experimental and Surgical Aspects of Retinal Pigment Epithelial Cell Transplantation.
`Eur J Implant Ref Surg 5:128-132, 1993.
`Del Priore LV. Surgical Management of Idiopathic Macular Holes. European Journal of
`Ophthalmology 4:35-42, 1994.
`Bynoe LA, Chang TS, Funata M, Del Priore LV, Kaplan HJ, Green WR. Histopathologic
`Examination of Vascular Patterns in Subfoveal Neovascular Membranes. Ophthalmology
`101:1112-1117, 1994.
`Arfken C, Salicrup A, Meuer S, Del Priore LV, Klein R, J. McGill, Rucker C, White N,
`Santiago J. Retinopathy in African Americans and Whites with Insulin Dependent
`Diabetes Mellitus. Arch Intern Medicine 154:2597-2602, 1994.
`Del Priore LV, Kaplan HJ, Bonham R. Laser Photocoagulation and Fluid-Gas Exchange
`for the Treatment of Recurrent Macular Hole. Retina 14:381-382, 1994.
`De Ungria JM, Del Priore LV, Hart W. Abnormal Disc Vessels after Diabetic
`Papillopathy. Arch Ophthalmol 113:245-246, 1995.
`Desai VN, Del Priore LV, Kaplan HJ. Choriocapillaris Atrophy after Submacular Surgery
`in the Presumed Ocular Histoplasmosis Syndrome. Arch Ophthalmol 113:409-410, 1995.
`
`Exhibit 2081
`Page 14 of 58
`
`

`

`Del Priore: curriculum vitae Page 15
`
`26.
`
`27.
`
`28.
`
`29.
`
`30.
`
`31.
`
`24.
`
`Valentino TL, Kaplan HJ, Del Priore LV, Fang SR, Berger A, Silverman MS. Retinal
`Pigment Epithelial Repopulation in Monkeys after Submacular Surgery. Arch
`Ophthalmol 113:932-938, 1995.
`25. Matsumoto B, Del Priore LV. Transretinal Membrane Formation in Diffuse Unilateral
`Subacute Neuroretinitis. Retina 15:146-149, 1995.
`Del Priore LV, Hornbeck R, Kaplan HJ, Jones Z, Valentino TL, Mosinger-Ogilvie J,
`Swinn M. Debridement of the Pig Retinal Pigment Epithelium In Vivo. Arch Ophthalmol
`113:939-944, 1995.
`Adelberg DA, Del Priore LV, Kaplan HJ. Surgery for Subfoveal Membranes in Myopia,
`Angioid Streaks, and Other Disorders. Retina 15:198-205, 1995.
`Del Priore LV, Kaplan HJ. Pathogenesis of Age-related Macular Degeneration (letter).
`Ophthalmology 102:1125-1126, 1995.
`Akduman LA, Del Priore LV, Kaplan HJ, Meredith TA. Uveal Effusion Syndrome
`Associated with Primary Pulmonary Hypertension and Vomiting. Am J Ophthalmology
`121:578-580, 1996.
`Tezel TH, Del Priore LV. Density-dependent Growth Regulation of Pig Retinal Pigment
`Epithelial Cells In Vitro. Graefe’s Arch Clinical and Experimental Ophthalmology
`234:S89-95, 1996.
`Pollack JS, Del Priore LV, Smith ME, Feiner MA, Kaplan HJ. Postoperative
`Abnormalities of the Choriocapillaris in Exudative Age-related Macular Degeneration.
`Brit J Ophthalmol 80:314-318, 1996.
`Akduman LA, Kolker AE, Black DL, Del Priore LV, Kaplan HJ. Treatment of Persistent
`Glaucoma Secondary to Periocular Corticosteroids. Am J Ophthalmol 122:275-277,
`1996.
`Del Priore LV, Kaplan HJ, Hornbeck R, Jones Z, Swinn M. Retinal Pigment Epithelial
`Debridement as a Model for the Pathogenesis and Treatment of Macular Degeneration.
`Am J Ophthalmol 122:629-643, 1996.
`Tezel TH, Del Priore LV, Flowers BE, Grosof D, Benenson IL, Zamora RL, Kaplan HJ.
`Correlation between Scanning Laser Ophthalmoscope (SLO) Microperimetry and
`Anatomic Abnormalities in Patients with Subfoveal Neovascularization. Ophthalmology
`103:1829-1836, 1996.
`Zamora RL, Del Priore LV, Storch GA, Gelb LD, Sharp J. Multiple Recurrent Branch
`Retinal Artery Occlusions Associated with Varicella Zoster Virus. Retina 16:399-404,
`1996.
`Ho TC, Del Priore LV, Kaplan HJ. En Bloc Transfer of Extracellular Matrix In Vitro.
`Curr Eye Res 15:991-997, 1996.
`Akduman LA, Del Priore LV, Kaplan HJ, Powderly WG. Rifabutin-induced Vitritis in
`AIDS Patients. Ocular Immunology and Inflammation 4:219-224, 1996.
`Ho TC, Del Priore LV, Kaplan HJ. Tissue Culture of Retinal Pigment Epithelium
`Following Isolation with a Gelatin Matrix Technique. Exp Eye Research 64:133-139,
`1997.
`Akduman LA, Desai VN, Del Priore LV, Olk RJ, Kaplan HJ. Visual Improvement After
`Subfoveal Surgery in POHS Depends on Perfusion of Subfoveal Choriocapillaris. Am J
`Ophthalmol 123:90-96,1997.
`Ho TC, Del Priore LV. Reattachment of Human Retinal Pigment Epithelium to
`Extracellular Matrix and Human Bruch’s Membrane. Invest Ophthalmol Vis Sci
`38:1110-1118,1997.
`
`32.
`
`33.
`
`34.
`
`35.
`
`36.
`
`37.
`
`38.
`
`39.
`
`40.
`
`Exhibit 2081
`Page 15 of 58
`
`

`

`41.
`
`42.
`
`43.
`
`44.
`
`45.
`
`46.
`
`47.
`
`48.
`
`49.
`
`50.
`
`51.
`
`52.
`
`53.
`
`54.
`
`55.
`
`56.
`
`57.
`
`Del Priore: curriculum vitae Page 16
`
`Tezel TH, Del Priore LV, Kaplan HJ. Reattachment to a Substrate Prevents Apoptosis of
`Human Retinal Pigment Epithelium. Graefe’s Arch Clin Exp Ophthalmol 235:41-47,
`1997.
`Berman A, Del Priore LV, Fischer CK. Endogenous Ochrobactrum Anthropi
`Endophthalmitis. Am J Ophthalmol 123:560-562, 1997.
`Akduman LA, Adelberg DA, Del Priore LV. Nanophthalmic Uveal Effusion Managed
`with Scleral Windows and Topical Mitomycin-C. Ophthalmic Surgery and Lasers
`28:325-327, 1997.
`Del Priore LV, Kaplan HJ, Berger AS. Retinal Pigment Epithelial Transplantation in the
`Management of Subfoveal Choroidal Neovascularization. Seminars in Ophthalmology
`12:45-55, 1997.
`Ho TC, Del Priore LV, Hornbeck R. Effect of Mitomycin-C on Human Retinal Pigment
`Epithelium in Tissue Culture. Curr Eye Res 16:572-576, 1997.
`Tezel TH, Del Priore LV, Kaplan HJ. Harvest and Storage of Adult Human Reti