`~ Know more. Be sure.
`
`FDA Approves Avastin
`Avastin Approved for treatment for Metastatic Colorectal Cancer
`
`Avastin (bevacizumab) is a recombinant humanized monoclonal lgG1 antibody which in
`combination with intravenous 5-fluorouracil-based chemotherapy, is indicated for first- or second(cid:173)
`line treatment of patients with metastatic carcinoma of the colon or rectum.
`
`Posted : February 2004
`
`Related Articles:
`
`• FDA Approves Genentech's Avastin (bevacizumab) Plus Chemotherapy as a Treatment for
`Women With Advanced Ovarian Cancer Following Initial Surgery - June 13, 2018
`
`• FDA Grants Genentech's Avastin Full Approval for Most Aggressive Form of Brain Cancer -
`December 5, 2017
`
`• FDA Approves Avastin (bevacizumab) Plus Chemotherapy for a Specific Type of Advanced
`Ovarian Cancer - December 6, 2016
`
`• FDA Approves Avastin (bevacizumab) Plus Chemotherapy for Platinum-Resistant Recurrent
`Ovarian Cancer- November 14, 2014
`
`• FDA Approves Avastin for Metastatic Cervical Cancer - August 14, 2014
`
`• FDA Revokes Breast Cancer Indication for Avastin (bevacizumab)- November 18, 2011
`
`• FDA Approves Avastin for the Most Common Type of Kidney Cancer - August 3, 2009
`
`• FDA Grants Accelerated Approval of Avastin for Brain Cancer (Glioblastoma) That Has
`Progressed Following Prior Therapy - May 6, 2009
`
`• FDA Grants Accelerated Approval of Avastin in Combination With Paclitaxel Chemotherapy for
`First-Line Treatment of Advanced HER2-Negative Breast Cancer - February 25, 2008
`
`• FDA Approves Avastin in Combination With Chemotherapy for First-Line Treatment of Most
`Common Type of Lung Cancer - October 11 , 2006
`
`• Avastin Filed in US for Treatment of Most Common Form of Lung Cancer - April 12, 2006
`
`Avastin (bevacizumab) FDA Approval History
`
`https://www.drugs.com/newdrugs/avastin-approved-metastatic-colorectal-cancer-21.html
`
`Novartis Exhibit 2262.001
`Regeneron v. Novartis, IPR2021-00816
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`