FILE HISTORY
`10/037,266
`
`INVENTORS: David Paniagua
`Eduardo lnduni
`Carlos Mejia
`Francisco Lopez-Jinerez
`R. David Fish
`
`TITLE:
`
`Percutaneously implantable replacement
`heart valve device and method of making
`same
`
`APPLICATION 101037 266
`NO:
`'
`FILED:
`04 JAN 2002
`
`COMPILED:
`
`12 AUG 2020
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 1 of 115
`
`

`

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`: ""'APPLICANTS:
`Francisco; Fish R.;
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`====
`U.S. UTILITY Patent Application
`"t =
`0
`~~::::::,:::::::::;;;:::::::::::::::::::;===::::;=::::::::::=:;::=:::;:============::,
`APPL NUM
`FILING DATE CLASS SUBCLASS GAU
`EXAMINER
`61/ (?l ·;-:'-r1'
`2, I/
`10037266
`01/04/2002
`623
`3738
`Paniagua David; lnduni Eduardo; Mejia Carlos; L1.1pez-Jinerez
`
`PATENT NUMBER and
`ISSUE DATE
`'
`
`BEST COPY
`
`**CONTINUING DATA VERIFIED:
`
`** FOREIGN APPLICATIONS VERIFIEf"\·
`
`PG-PUB lo0 ~.
`
`. JDLISH □
`
`RESCIND □
`
`,d
`□ yes □ no
`, 1ditloris met
`35 LJ,
`□ yes □ no
`Verified and Acknowledged Examiners's intiafs ·
`
`!ATTORNEY DOCKET NO,,
`
`1
`
`51458.010100
`
`1
`
`I
`TITLE : Percutaneously implantable replacement heart valve device and method of making same
`U.S.DEPT. OF COMM./PAT.& TM-PT0-436L(Rey, ~
`
`NOTICE OF ALLOWANCE MAILED
`
`ISSUE FEE
`Amount Due
`Date Paid
`
`Assistant Examiner
`
`CL.ki
`., .
`
`Total Cla'
`-
`-
`
`. /
`
`..
`~: f;' Drwg.
`
`Print Claim for
`p.G
`DRAWING
`Flgs.Drwg.
`
`Print Fig,
`
`□ TERMINAL
`DISCLAMER
`
`Primary Examiner
`
`i -,
`
`Examiner
`Hppllcation
`PREPARED FOR lSSUE
`WARNING: The infonnation disc0_J herein may be restricted.
`Unauthorized disclosure may be prc,.,,Uited by the Uni ted States Code Title 35,
`Sections 122, 181 and 368, Possesr. e,n outside the U.S.
`Patent & Trademark
`tors onl .
`Office is restricted to authorized}7l.lDloyees and contrac
`[j DISK (CRF)
`□ CC-ROM
`(Attached In Pocket on right inside lap)
`
`FILED WITH:
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 2 of 115
`
`

`

`10/037,266
`
`Percutaneously implantable replacement heart valve device and method of
`making same
`
`Transaction History
`
`Transaction Description
`Date
`Information Disclosure Statement (IDS) Filed
`01-04-2002
`Information Disclosure Statement (IDS) Filed
`01-04-2002
`Initial Exam Team nn
`01-04-2002
`IFW Scan & PACR Auto Security Review
`01-27-2002
`02-14-2002 Application Is Now Complete
`02-15-2002 Annlication Dispatched from OIPE
`03-17-2002 Case Docketed to Examiner in GAU
`05-05-2003 Non-Final Rejection
`05-08-2003 Mail Non-Final Reiection
`Informal or Non-Responsive Amendment after Examiner Action
`08-06-2003
`08-06-2003 Response after Non-Final Action
`09-17-2003 Date Forwarded to Examiner
`11-19-2003 Mail Notice oflnformal or Non-Responsive Amendment
`12-09-2003 Response after Non-Final Action
`12-23-2003 Date Forwarded to Examiner
`03-08-2004 Final Reiection
`03-09-2004 Mail Final Rejection (PTOL - 326)
`07-10-2004 Workflow incoming amendment IFW
`09-14-2004 Mail Abandonment for Failure to Respond to Office Action
`09-14-2004 Aband. for Failure to Respond to 0. A.
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 3 of 115
`
`

`

`O')O>t,.J~WOO_..
`lllll\\llllllllllllllllllll\llll\llllllllllll\llll
`10037266
`
`jc872 U.S. PTO
`
`10/037266
`llllllllllllllllllllllllllllllllllllllll
`01/04/021NITIALS __ _
`
`CONTENTS,:·. I •1, -:. :~,a,·~· iD··
`
`Date
`.Received
`(incl. C. of M.)
`or
`Date Mailed
`
`/ ,, :,
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`
`I
`
`Date
`Recelvea
`{Incl. C. of M.}
`er
`Dal&Mai:§d
`
`Application
`
`- -
`
`papers.
`
`31. ____ _
`
`\
`
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`
`32.
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`55.
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`56.
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`57.
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`58.
`
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`
`so.
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 4 of 115
`
`

`

`CLASSIFICATION NOTES
`Examiner/
`·initials
`Classifier
`
`Class
`
`Date
`
`POSIT~ON
`FEE DETERMINATION
`FILE ASSEMIBL Y
`QUALITY CHECK
`SCANNING
`CLASSIFIER
`FORMALITY REVIEW
`RESPONSE
`
`"
`
`.
`¼A6..J:..
`"O'V1)
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`NAME
`
`IDNO.
`
`DATE
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`
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`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 5 of 115
`
`

`

`ISSUE SLIP STAPLE AREA <for additional cross-referencesl
`ISSUING CLASSIFICATION
`CROSS REFERENCE($)
`SUBCLASS (ONE SUBCLASS PER BLOCK)
`
`CLASS
`
`ORIGfNAL
`I SUBCLASS
`CLASS
`I
`
`INTERNATIONAL
`CLASSIFICATION
`
`1
`I
`I
`I
`I
`
`.. . .. .. .. ~~.
`Clatm
`l
`
`- ~ ~ 0
`
`Date
`
`A Continued on Issue Slip Inside File Jacket
`INDEX OF CLAIMS
`✓ ............... Reiecled
`- (Through numeral) .•. Canceled
`N ............... Non-elected A ............... Appeal
`...............
`lnte
`Restricted
`............... Allowed
`rference 0 ............... Oblected
`I
`+ . •• • ... .. .. ...
`Claim
`Date
`Claim
`Date
`ii
`C:
`1 ~
`u: 0
`51
`101
`52
`102
`53
`103
`54
`104
`55
`105
`56
`106
`107
`57
`58
`106
`109
`59
`60
`110
`111
`61
`112
`62
`63
`113
`64.
`· 114.
`65
`115
`66
`116
`67
`117
`118
`68
`119
`69
`70
`120
`121
`71
`72
`122
`73
`123
`12-4
`74
`125
`75
`126
`76
`127
`77
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`129
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`130
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`131
`81
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`M
`134
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`136
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`141
`91
`142
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`144
`94
`1-45
`95
`146
`96
`147
`97
`1-48
`98
`149
`99
`..
`150
`100
`If more than 150 claims or 9 actions staple add1t1onal sheet here
`
`_J,..
`
`9
`10
`11
`12
`13
`
`15
`16
`,< 17
`18
`19
`20
`21
`22
`23
`24
`25
`26
`27
`28
`29
`30
`31
`32
`33
`34
`35
`36
`37
`38
`39
`40
`41
`42
`43
`44
`45
`46
`47
`
`~
`
`:
`
`I
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 6 of 115
`
`

`

`SEARCH
`
`Class Sub. Date Exmr.
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`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 7 of 115
`
`

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`( ( (623/2 .1-2 .19) .CC:LS.)
`and (@rlad<20020104))
`(((623/2.1-2.19) .CCLS.) and
`(@ptld<20020104))
`( ( ( 623/2 .1-2. 19) . CCLS.)
`and (@pt3d<20020104))
`(((623/2.1-2.19) .CCLS.) and
`(@ptpd<20020104))
`((((623/2.1-2.19).CCLS.) and
`(@ad<20020104))
`( ( (623/2 .1-2 .19) .CCLS.)
`and (@rlad<20020104))
`(((623/2.1-2.19) .CCLS.) and
`(@ptld<20020104))
`( ( (623/2 .1-2 .19) .CCLS.)
`and {@pt3d<20020104))
`"(((623/2.1-2.19) .CCLS.) and
`(@ptpd<20020104))) and (nitinol titanium
`stainless)
`(((((623/2.1-2.19) .CCLS.) and
`(@ad<20020104))
`( ( (623/2 .1-2 .19) .CCLS.)
`and (@rlad<20020104))
`(((623/2.1-2.19) .CCLS.) and
`(@ptld<20020104))
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`and (@pt3d<20020104))
`(((623/2.1-2.19) .CCLS.) and
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`stainless)) and bovine and porcine and
`autologous
`19 fold same pericardium
`
`415
`
`200
`
`24
`
`3
`
`4
`
`USPAT;
`US-PG PUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/J3
`16: 47
`
`2003/05/'.)3
`16:47
`
`2003/05/)3
`16:47
`
`2003/05/'.)3
`16:47
`
`2003/05/03
`16:47
`
`2003/05/03
`16:48
`
`2003/05/03
`16:48
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/03
`16:49
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/0'::
`11 :38
`
`2003/05/0<&
`11: 29
`
`2003/05/C4
`11:30
`
`2003/05/(4
`11;32
`
`2003/05/[4
`11:34
`
`(fold same pericardium) and stent
`
`,
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`(fold same pericardium) and (frame stent) USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`4351 valve and (within near (frame stent))
`
`Search History
`
`5/5/03 10:50:07 AM
`
`p·age 1
`
`C:\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 8 of 115
`
`

`

`857
`
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`and (@pt3d<20020104})
`(((623/2.1-2.19).CCLS.) and
`(@ptpd<20020104})) and (nitinol titanium
`stainless)) and
`(bovine porcine
`autologous)
`((((((623/2.1-2.19).CCLS.) and
`( ( ( 623/2. 1-2 .19). c:::Ls.)
`(@ad<20020104))
`and (@rlad<20020104))
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`(@ptld<20020104)) (((623/2.1-2.19) .CCLS.)
`and (@pt3d<20020104))
`(((623/2.1-2.19) .CCLS.) and
`(@ptpd<20020104))) and (nitinol titanium
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`("3714671"
`
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`autologous)) and {rectangle rectangular
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`valve and ((tissue same within) same
`stent)
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`( valve and ((tissue same within) same
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`square)
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`
`4
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`26 3739402.URPN.
`
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`
`8
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`14 4340977.URPN.
`
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`DERWENT
`USPAT;
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`EPO; JPO;
`DERWENT
`
`2003/05/)4
`12:23
`
`2003/05/04
`11:34
`
`2003/05/04
`11:37
`
`2003/05/04
`11:39
`
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`US-PGPUB;
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`DERWENT
`
`2003/05/04
`11 :50
`
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`
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`DERWENT
`
`2003/05/C'::
`11:41
`2003/05/0?
`11:48
`
`USPAT;
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`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`2003/05/G?
`11: 49
`
`2003/05/04
`12:07
`
`2003/05/04
`11:53
`
`2003/05/04
`12:00
`2003/05/04
`12:00
`2003/05/04
`12:03
`2003/05/04
`12:03
`2003/05/04
`12:03
`
`2003/0S/:J4
`12:03
`
`Search History
`
`5/5/03 10:50:07 AM
`
`p·age 2
`
`C:\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 9 of 115
`
`

`

`-
`
`-
`
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`
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`I "4247292" I "4297749" 1
`"4211241"
`I "4470157" I "4490859" !
`"4388735"
`I "4512471"
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`I "4643732"
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`50 5163955.URPN.
`
`12
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`14 5509930.URPN.
`
`I
`
`9
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`"4451936"
`I "4624822"
`I "5197979"
`"5139515"
`10 5S45215.URPN.
`
`I "4372743"
`I "4692164" !
`I "5376112"). PN.
`
`I
`
`,..:lPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`USPAT
`
`!
`
`i
`
`2003/05/04
`12:03
`
`2003/05/04
`12: 03
`2003/05/04
`12:03
`
`2003/05/04
`12:04
`2003/05/04
`12:04
`
`2003/05/0f
`12:04
`2003/05/Cf
`12:04
`
`2003/05/04
`12:04
`2003/05/04
`12:04
`
`2003/05/04
`12:04
`2003/05/0',
`12:04
`
`2003/05/0<:
`12:05
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 3
`
`C:\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 10 of 115
`
`

`

`_<SPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/04
`12:07
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/0':
`12:07
`
`I
`
`I
`
`( ("35 _ .,18" I "3570014" I "3451067" I
`"3263239") .PN.) 3739402.URPN.
`( ("3714671"
`I "4084268"} .PN.) 4172295.URPN.
`(("3608097" I "3655306"
`J "3710744"
`I "3739402"
`I "3755823"
`I
`"3714671"
`"4172295"
`l "4222126") .PN.) 4340977.URPN.
`(("3548418" I "3655306" I "3739402" I
`I
`I "3983581"
`I "4035849"
`"3755823"
`"4084268"
`I "4172295 ") . PN.) 4477930. URPN.
`I "4090878" I "4247292" I
`( ("3966401"
`I "4350492"
`I
`I "4473423"
`"4340977"
`"4477930") .PN.) 4624822.URPN.
`( ("2822819"
`I "2922437"
`I "3548418"
`I "3570014"
`I
`I "3755823"
`I "3967645"
`I
`"3589392"
`"3983581" I "4011947" I "4035849" I
`I
`I "4101031"
`I "4106129"
`"4065816"
`I "4192020"
`I "4211241"
`I
`"41B2446"
`I "4297749"
`I "4388735"
`I
`"4247292"
`I "4490B59"
`I "4501030"
`I
`"4470157"
`I "4535819"
`I "4597767"
`I
`"4512471"
`I "_4643732"
`I "4679556"
`I
`"4605407"
`I "4725274"
`I "4B01015"
`I
`"4687483"
`I "4881562") .PN.) 5163955.URPN.
`"4838288"
`I "4108161"
`I "4211325" I
`(("3966401"
`I "4512471"
`I "4601718"
`I
`"4470157"
`I "4838288"
`I "4960424"
`I
`"4801299"
`I "5163955"
`I "5344442") .PN.)
`"5031762"
`( ("3655306" I "3686740"
`I
`5480424.URPN.
`I "4172295"
`I
`I "421878 2 "
`"4079468"
`I "4629459"
`I "4790844"
`I
`"4470157"
`I "5197979"
`I "5215-541") .PN.)
`"4960424"
`I
`I "4343048"
`5509930.URPN.
`( ("4218782"
`I "4451936"
`I "4624822"
`I
`"4372743"
`I "5139515"
`I "5197979"
`I
`"4692164"
`"5376112") . PN.) 5545215. URPN.
`I
`( (("3548418" I "3570014"
`I "3451067"
`"3263239") .PN.) 3739402.URPN.
`( ("3714671"
`I "4084268") .PN.) 4172295.URPN.
`I "3655306" I "3710744''
`( ("3608097"
`"3714671"
`I "3739402"
`I "3755823" I
`"4172295"
`I "4222126").PN.) 4340977.URPN.
`(("3548418" I "3655306" I n3739402~ I
`I "3983581"
`I "4035849"
`I
`n3755a23 11
`"4084268"
`I "4172295") .PN.) 4477930.URPN.
`(("3966401" I "4090878" I "4247292~ I
`"4340977" I "43~0492" I "4473423" I
`"4477930") .PN.) 4624822.URPN.
`(("2822819"
`I "2922437"
`I "3548418" I "3570014n I
`"3589392" I "3755823" I "3967645"
`I
`"3983581" ! "4011947" I "4035849"
`I
`"4065816"
`r "4101031"
`r "4106129"
`1
`I "4192020" ! "4211241"
`"4182446"
`"4247292" I "4297749" ! "4388735" I
`"4470157" I "4490859" I "4501030" I
`"4512471" I "4535819" I "4597767" I
`"4605407" I "4643732" I "4679556" !
`"4687483" I "4725274" I "4801015" I
`"48382ll8" I "4881562") .PN.) 5163955.URPN.
`({"3966401" I "4108161" I "4211325"
`I
`"4470i57" I "4512471" I "4601718" I
`I "4838288" I "4960424"
`I
`"4801299"
`I "5163955"
`"5031762"
`I "5344442") .PN.)
`548'0424.URPN.
`( ("3655306" I "3686740" I
`I "4172295"
`I "4218782" I
`"4079468"
`"4470157"
`I "4629459" I "4790844" I
`I "5197979"
`I "5215541") .PN.)
`"4960424"
`5509930.URPN. (("4218782" I "4343048" I
`"4372743"
`I "4451936" I "4624822" I
`I
`I "5139515"
`I "5197979"
`"4692164"
`"5376112 '~) . PN.) 5545215. URPN.) and
`(rectangle rectangular 'square)
`
`225
`
`68
`
`J
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 4
`
`C:\APPS\EAST\workspaces\10037266 heart vaive.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 11 of 115
`
`

`

`17
`
`14
`
`10
`
`(US-61~-~86-$ or US-5545215-$ or
`US-54B0424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$) .did. or (US-20020138:38-$
`or US-20030040792-$) .did.
`((US-6126686-$ or US-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$) .did. or (US-20020138:38-$
`or US-20030040792-$) .did.) and within
`(((US-61266B6-$ or US-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`us-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`us-4470157-$ or US-4692164-$ or
`US-5865723-$) .did. or (US-2002013813B-$
`or US-20030040792-$) .did.) and within)
`and bovine
`((((0S-6126686-$ or us-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$) .did. or (US-20020138138-$
`or US-20030040792-$) .did.) and within)
`and bovine) and porcine
`(((((US-6126686-$ or us-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`us-4340977-$ or us~4172295-$ or
`us-5509930-$ or us-4624822-$ or
`us-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$) .did. or (US-20020138138-$
`or US-20030040792-$) .did.) and within)
`and bovine} and porcine) and autologous
`((((((US-6126686-$ or us-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`us-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`us-4470157-$ or US-4692164-$ or
`US-586S723-$) .did. or (US-20020138:38-$
`or US-,20030040792-$) .did.} and within)
`and bovine) and porcine) and autologous)
`and (titanium nitinol stainless)
`10 55'!._5215. URPN.
`
`10
`
`7
`
`7
`
`12
`
`139
`
`I "5413599"
`I "5397351"
`("4787901"
`"5545215" I "5549665" I "5891195"
`"5957949" I "6027525" I "6110201"
`"6168614" I "6254642" I "6264700") .PN.
`(623/1.24-1.26) .CCLS.
`
`I
`
`Search History
`
`5/5/03 10:50:07 AM
`
`P:age 5
`
`c:\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`~PAT;
`US-PGPUB
`
`2003/05/C4
`12:14
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/04
`12:23
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/(4
`13:26
`
`US PAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/(4
`12:23
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/'.:>4
`12:23
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/C4
`13:24
`
`USPAT
`
`US PAT
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/C4
`13:21
`2003/05/04
`13:23
`
`2003/05/04
`13:25
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 12 of 115
`
`

`

`· 71162 79and .. ;ine
`
`19
`
`((623/1.24-1.26) .CCLS.) and bovine
`
`2
`
`( ("5855597") or ("6162245")) .PN.
`
`1428
`
`(gluteraldehyde glutaraldehyde) SP.ME
`ETHANOL
`
`17
`
`((gluteraldehyde glutaraldehyde) SAME
`ETHANOL) and (porcine and bovine and
`autologous)
`
`7
`
`(((gluteraldehyde glutaraldehyde) SAME
`ETHANOL) and (porcine and bovine and
`autologous)) and valve
`
`45
`
`( (gluteraldehyde glutaraldehyde) SAME
`ETHANOL) and stent
`
`300
`
`((gluteraldehyde glutaraldehyde) SAME
`ETHANOL) same (dry dried)
`
`12
`
`(( (gluteraldehyde glutaraldehyde) SAME
`ETHANOL) same (dry dried)) and stent
`
`166
`
`( ((gluteraldehyde glutaraldehyde) SAME
`ETHANOL) same (dry dried)) and bovine
`
`64
`
`33
`
`({((gluteraldehyde glutaraldehyde) SAME
`ETHANOL) same (dry dried)) and bovine)
`and heart
`
`(((gluteraldehyde glutaraldehyde) SAME
`ETHANOL) same (dry dried)) and {bovine
`same porcine)
`
`9779
`
`(gl uteraldehyde -glutaraldehyde) an::i
`ETHANOL
`
`2499 {(gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart
`
`512
`
`(( (gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve
`
`61
`
`(({(gl\!lteraldehyde glutaraldehyde) and
`ETHANQL) and heart) and valve) and stent
`
`46
`
`( ((( (gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and stent)
`and (dryed dried drying dry)
`
`3 5746775.URPN.
`
`,PAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US - PGPUB;
`EPO; JPO;
`DERWENT
`USPAT
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`US PAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`BPO; JPO;
`DERWENT
`USPAT
`
`2003/05/:4
`13:27
`
`2003/05/C:4
`13:39
`
`2003/05/04
`13:46
`2003/05/04
`14:02
`
`2003/05/04
`13:47
`
`2003/05/04
`13:50
`
`2003/05/04
`13:55
`
`2003/05/04
`13:55
`
`2003/05/04
`13:58
`
`2003/05/04
`14:01
`
`2003/05/C4
`13:58
`
`2003 / 05/C4
`14:01
`
`2003/05/C4
`14:27
`
`2003/05/(4
`14 :02
`
`2003/05/(4
`14:03
`
`2003/05/(4
`14:06
`
`2003/05/C,.;
`14: 13
`
`2003/05/C.;
`14:08
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 6
`
`C:\APPS\EAST\workspaces\10037266 heart va~ve.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 13 of 115
`
`

`

`452
`
`( ( ( (gi._ .craldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and (dryed
`dried drying dry)
`
`0
`
`((( (gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and (then
`adj (dryed dried drying dry))
`
`307
`
`( (((gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) anc
`(ethanol same (dryed dried drying dry))
`
`133
`
`117
`
`133
`
`(((((gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same (dryed dried drying dry)))
`and (bovine and porcine)
`( ((((gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same (dryed dried drying dry)))
`and (autologous and bovine and porcine)
`(((((gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same (dryed dried drying dry)))
`and (bovine and porcine)
`((((({gluteraldehyde glutaral dehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same (dryed dried drying dry)))
`and (bovine and porcine)) not
`((((( (gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same {dryed dried drying dry)))
`and (autologous and bovine and porcine))
`((( ((gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same (dryed dried drying dry)))
`and fixing
`( ((( ((gluteraldehyde glutaraldehyde) and
`ETHANOL) and heart) and valve) and
`(ethanol same (dryed dried drying dry)))
`and fixing) and tissue
`·
`909 {gluteraldehyde glutaraldehyde) and
`((rinse rinsed) same ETHANOL)
`
`16
`
`188
`
`188
`
`817
`
`427
`
`185
`
`137
`
`2
`
`10
`
`((gl uterald€hyde glutaraldehyde) and
`( (rinse "rinsed) ,same ETHANOL)) and (dr yed
`dried drying dry)
`
`(gluteraldehyde glutaraldehyde) and
`(((rinse rinsed} same ETHANOL) same
`(dryed dried drying dry)}
`
`((gluteraldehyde glutaraldehyde) and
`(((rinse rinsed) same ETHANOL) same
`(dryed dried drying dry))) 1and
`(prosthetic implant)
`(((gluteraldehyde glutaraldehyde) and
`(((rinSle rinsed} same ETHANOL) same
`(dryed,dried drying dry))) and
`(prosthetic implant)) and (valve valves)
`("5855597") .PN.
`
`I "4297749"
`I "4056854"
`("3671979"
`I "5397355" I "5507771"
`''5332402"
`"5522881" I "56 1 8301"
`I "5769887"
`"5776161") .PN.
`
`I
`I
`
`I
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 7
`
`C:\APPS\EAST\workspaces\10037266 heart valVe.wsp
`
`_.;PAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US - PGPUB;
`EPO; JPO;
`DERWENT
`
`USPAT;
`US-PGPUB;
`EPO,· JPO;
`DERWENT
`USPAT;
`US - PGPUB;
`EPO;
`JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT
`
`2003/05/:)4
`14:28
`
`2003/05/'J-4
`14:13
`
`2003/05/J4
`14:14
`
`2003/05/04
`14:14
`
`2003/05/04
`14 :17
`
`2003/05/04
`14: 17
`
`2003/05/04
`14:25
`
`2003/05/C?
`14:25
`
`2003/05/0~
`14:25
`
`2003/05/0-4
`14:28
`
`2003/05/04
`14:28
`
`2003/05/04
`14 :.29
`
`2003 / 05/04
`14 :31
`
`2003/05/04
`14:31
`
`2003/05/04
`15:45
`
`2003/05/04
`15:44
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 14 of 115
`
`

`

`4
`
`I "4297749"
`I "4056854"
`( ("36-, __ /9"
`I "5397355" I "5507771" I
`"5332402"
`I "5618301"
`I "5769887"
`I
`"5522881"
`"5776161") .PN.) and valve
`37 4297749.URPN.
`
`I
`
`22 4297749.URPN. and self
`
`22
`
`(4297749.URPN. and self) and valve
`
`7
`
`((4297749.URPN. and self) and valve) not
`love.in.
`
`(US-6126686-$ or US-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$ or US-6482228-$ or
`US-6027525-$ or US-6245102-$ or
`US-6440164-$ or us-5746775-$ or
`US-6471723-$ or US-5782914-$ or
`US-5855597-$ or US-6162245-$) .did. or
`(US-20020138138-$ or US-20030040792-$ or
`US-20010023372-$) .did.
`(US-3608097-$) .did.
`
`27
`
`1
`
`8
`
`7
`
`((US-6126686-$ or us-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865123-$ or US-6482228-$ or
`US-6027525-$ or ~S-6245102-$ or
`US-6440164-$ or US-5746775-$ or
`US-6471723-$ or US-5782914-$ or
`US-5855597-$ or US-6162245-$) .did. or
`(US-20020138138-$ or us-20030040792-$ or
`US-20010023372-$) .did.) and catheter
`(((US-6126686-$ or US-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`
`6~=i~6~~~6=: ~~ ~~=:~~~~~~~: ~~
`
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$ or US-6482228-$ or
`US-6027525-$ or US-6245102-$ or
`US-6440164-$ or US-5746775-$ or
`US~6471723-$ or US-5782914-$ or
`US-5855597-$ or US-6162245-$) .did. or
`(US-20020138138-$ or US-20030040792-$ or
`US-20010023372-$) .did.) and catheter) and
`bovine
`10 5545215.URPN.
`
`1 5545215.URPN. and catheter
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 8
`
`C:\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`.. ~PAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB
`
`2003/05/04
`15: 46
`
`2[03/05/04
`15:46
`2C03/05/04
`15:46
`
`2003/05/04
`15:47
`
`2003/05/04
`15:48
`
`2003/05/0~
`16:09
`
`USOCR
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/C4
`16:09
`2003/05/C4
`16:12
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`20".)3/05/0?
`16:10
`
`USPAT
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/04
`16:12
`2003/05/04
`16:14
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 15 of 115
`
`

`

`2003/05/04
`16:14
`
`2003/05/:4
`16:15
`
`2003/05/:4
`16:15
`
`2003/05/:4
`16:15
`
`2C03/05/C4
`16:16
`
`20:)3/05/04
`16:16
`
`2003/05/04
`16: 17
`
`I
`
`I
`
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`_$PAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`USPAT;
`( (valve and (percutaneous percutaneously
`catheter)) and stent) and (bovine porcine US-PGPUB;
`EPO; JPO;
`autologous)
`DERWENT
`( ( (valve and (percutaneous percutaneously USPAT;
`catheter)) and stent) and (bovine porcine US-PGPUB;
`EPO; JPO;
`autol ogous) ) not love.in.
`DERWENT
`( ( (valve and (percutaneous percutaneously US PAT;
`catheter)) and stent) and (bovine porcine US-PGPUB;
`EPO; JPO;
`autologous) ) not ( (US - 6126686-$ or
`DERWENT
`US-5545215-$ or US-5480424-$ or
`US-5163955-$ or US-4340977-$ or
`US-4172295-$ or US-5509930-$ or
`US-4624822-$ or US-3739402-$ or
`US-4477930-$ or US-61297S8-$ or
`US-4297749-$ or US-4470157-$ or
`US-4692164-$ or US-5865723 - $ or
`US-6482228-$ or US-6027525-$ or
`US-6245102-$ or US-6440164-$ or
`US-S746775-$ or US-6471723-$ or
`US-5782914-$ or US - 5855597-$ or
`US-6162245-$) .did. or (US-20020138138-$
`or us-20030040792-$ or
`US-20010023372-$) .did.)
`( ( ( (valve and (percutaneous
`percutaneously catheter)) and stent) and
`{bovine porcine autologous)) not
`{ ( US-612 668 6-$ or US-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or .US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$ or US-6482228-$ or
`US-6027525-$ or US-6245102-$ or
`US-6440164-$ or US-5746775-$ or
`US-6471723-$ or US-5782914-$ or
`US-5855597-$ or US-6162245 , $) .did. or
`{US-200201 38138-$ or US-20030040 7 92-$ or
`US-20010023372-$) .did.)) and
`glutarc1ldehyde
`
`-
`
`-
`
`-
`
`-
`
`-
`
`-
`
`l
`
`554521-.JRPN. and (percutaneous
`percutaneously catheter)
`
`13623 valve and (percutaneous percutaneously
`catheter)
`
`(valve and (percutaneous percutaneously
`catheter)) and stent
`
`1523
`
`319
`
`319
`
`310
`
`-
`
`81
`
`\ ·.
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 9
`
`C;\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 16 of 115
`
`

`

`.. .:iPAT;
`US-PGPUB;
`EPO; JPO;
`DERWENT
`
`2003/05/C4
`16:17
`
`-
`
`8
`
`. .Je and (percutaneous
`( ( ( ( (', •
`percutaneously catheter)) and stent) and
`(bovine porcine autologous)) not
`( (US-6126686-$ or US-5545215-$ or
`US-5480424-$ or US-5163955-$ or
`US-4340977-$ or US-4172295-$ or
`US-5509930-$ or US-4624822-$ or
`US-3739402-$ or US-4477930-$ or
`US-6129758-$ or US-4297749-$ or
`US-4470157-$ or US-4692164-$ or
`US-5865723-$ or US-6482228-$ or
`US-6027525-$ or US-6245102-$ or
`US-6440164-$ or US-5746775-$ or
`US-6471723-$ or US-5782914-$ or
`US-5855597-$ or US-6162245-$) .did. or
`(US-20020138138-$ or US-20030040792-$ or
`US-20010023372-$) .did.)) and
`glutaraldehyde) and valve.ti.
`
`Search History
`
`5/5/03 10:50:07 AM
`
`Page 10
`
`C:\APPS\EAST\workspaces\10037266 heart valve.wsp
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 17 of 115
`
`

`

`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`lllllmllllllllllllllllllllllllllllllllllllllllllllllllllllllllJIIII
`
`Bib Data Sheet
`
`SERIAL NUMBER
`10/037,266
`
`FILING DATE
`01/04/2002
`RULE
`
`CLASS
`623
`
`GROUP ART UNIT
`3738
`
`ATTORNEY
`DOCKET NO.
`51458.010100
`
`Page 2 of···
`
`COMMISSIONER FOR PATENTS
`UNITED STATES PATENT AND TRADEMARt OFF CE
`WASHINClON, 0.G. 202':!J
`www-uspto.gov
`
`CONFIRMATION NO. 61&C
`
`APPLICANTS
`Davld Paniagua, North Bay Village, FL;
`Eduardo lnduni, Alajuela, COSTA RICA;
`Carlos Mejia, Miami Beach, FL;
`Francisco Lopez-Jinerez, Rochester, MN;
`R. David Fish, Houston, TX;
`
`** CONTINUING DATA*************"*********** ff?
`
`** FOREIGN APPLICATIONS **"'*"'*"'*"""**"'***"'"'**rf(?'
`
`IF REQUIRED, FOREIGN FILING LICENSE GRANTED.,* SMALL ENTJTY **
`** 02/14/2002
`D yes to
`Foreign Priority claimed
`35 USC 119 (a-d) cond i t io~ 0 D Met after
`met
`wa
`-:-'~
`rllerified and
`--:'
`.
`l:xamin\lr's Signature 1
`Acknowledged
`ADDRESS
`Manuel R. Valcarcel, IV
`GREENBERG TRAURlG, P.A.
`1221 Brickell Avenue
`Miami ,FL 33131
`
`SHEETS
`STATE OR
`COUNTRY DRAWING
`FL
`9
`
`Initials
`
`TITLE
`
`TOTAL
`CLAIMS
`14
`
`INDEPENDEN-
`CLAIMS
`2
`
`°t:~--.
`
`Percutaneously implantable replacement heart valve device and method of making same
`I□ All Fees
`I□ 1.16 Fees (Filing) ;
`1 □ 1.17 Fees (Processing Ext. '.)f
`time)
`I □ 1.18 Fees (Issue)
`I□ Other
`I□ Credit
`
`FILING FEE FEE~: Authority has been given in Paper
`to charge/credit DEPOSIT ACCOUNT
`RECEIVED No.
`for following:
`No.
`370
`
`'
`
`I
`
`I
`I
`I
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p. 18 of 115
`
`

`

`B'ESTCOPY
`
`PATENT APPLICATION SERIAL NO. _______ _
`
`U.S. DEPARTMENT OF COMMERCE
`PATENT AND TRADEMARK OFFICE
`FEE RECORD SHEET
`
`0./10/2002 SDrnErnl 00000062 100372:66
`370.00 OP
`
`PTO-1556
`(5/87)
`·u.s. GPO: 20 □□-468-987/39595
`
`Edwards Lifesciences Corporation, et al. Exhibit 1018, p