throbber
I. Introduction
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`Lakshmi Prasad Dasi
`Georgia Institute of Technology
`Department of Biomedical Engineering
`Atlanta, Georgia, 30322
`Phone: (770) 335-8953
`URL: https://heartvalve.osu.edu/
`Biographical Narrative
`
`Lakshmi Prasad Dasi, Ph.D., is an established researcher in the field of prosthetic heart valves,
`cardiovascular biomechanics, biomaterials, and devices. He is a tenured Full Professor of Biomedical
`Engineering at the Department of Biomedical Engineering, Georgia Institute of Technology (effective Jan
`1 2020). Prior to this, he was a tenured Full Professor of Biomedical Engineering, of Surgery, and of
`Physiology and Cell Biology at The Ohio State University. He is also Affiliate Faculty, Center for
`Cardiovascular Research, Nationwide Children's Hospital Research Institute; and at the School of
`Biomedical Engineering of Colorado State University. Prof. Dasi earned his Ph.D. from Georgia Institute of
`Technology in 2004 with a focus in fluid dynamics and turbulence. He trained as a postdoctoral fellow and
`research engineer under Prof. Ajit Yoganathan’s mentorship at Georgia Tech where he transformed his
`research focus to heart valves, devices, and cardiovascular biomechanics. In 2009, he established the
`Cardiovascular Biofluid Mechanics Lab (CBFL) as Assistant Professor at Colorado State University and
`moved to The Ohio State University in 2015 as his focus became more translational. Since then, his
`research has focused on tackling the complexity of: (a) heart valve biomechanics (native and prosthetic);
`(b) prosthetic heart valve engineering (conventional & trans-catheter); (c) structure-function relationships
`of the heart in health and disease at the embryonic, pediatric, as well as adult stages; and (d) turbulence
`and turbulent blood flow. To date, Dr. Dasi’s work has resulted in over 80 peer-reviewed journal
`publications and over 175 conference proceedings in the areas of mechanics and cardiovascular research.
`As an example of the depth and breadth of his research contributions, overall publications tackle: (1)
`understanding the vortex dynamics of native heart valves, and the impact of coronary flow, (2)
`formulation of a theory to predict mechanical loading on blood cells in turbulent flows, (3) impact of
`altered mechanics as epigenetic factors during embryonic heart development, (4) quantification of the
`thrombo-embolic potential of prosthetic heart valves using Lagrangian blood damage indices, (5) patient
`specific interactions of trans-catheter aortic valves, (6) unification of energy based clinical indices for
`multiple heart valve diseases, and (7) the fundamental structure of turbulent flows. All of these
`contributions either led to, or are a product of highly competitive national level research grants from the
`National Institutes of Health (NIH), National Science Foundation (NSF), and American Heart Association
`(AHA). Dr. Dasi has been Principal Investigator of grants totaling to over $6M in funding with an additional
`$7M in federal funding (as PI) currently pending to further broaden the scope of research undertaken by
`CBFL into the new area of personalized trans-catheter heart valve engineering. Dr. Dasi has 8 patents and
`is actively involved in commercialization of his recent technologies dealing with trans-catheter heart
`valves as well as predictive computational models for trans-catheter aortic valve therapy. Dr. Dasi is also
`involved in international partnerships with the goal of developing low cost heart valves in low-resource
`countries and has received special funding from the NIH as well as Indian government in this effort. Overall
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`Dr. Dasi’s research lab has trained 8 Ph.D. students (4 graduated), and 4 post-docs in addition to
`undergraduate students. Dr. Dasi has received several awards including the Melissa G. Piper Distinguished
`Mentor Award, George T. Abell Outstanding Teaching & Service Faculty Award, George T. Abell
`Outstanding Early-Career Faculty Award, and the American Heart Association’s National Scientist
`Development Award. Dr. Dasi also serves on the editorial board of the Annals of Biomedical Engineering
`in addition to serving as reviewer on NIH, AHA, and NSF grant study section/panels in addition to
`international funding agencies. He actively organizes symposiums and sessions related to heart valve
`engineering at national and international meetings such as at the World Congress of Biomechanics,
`Summer Biomechanics, Bioengineering, and Biotransport Conference, Heart Valve Society, and the U.S.
`National Congress for Theoretical and Applied Mechanics..
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`
`CurrentAppointments
`
`08/2020 - Present
`
`01/2020 - Present
`
`AcademicAppointments
`
`2015 - 05/2019
`
`2015 - 05/2019
`
`
`2015 - 05/2019
`
`2015 - 2015
`
`2015 - 2015
`
`2009 - 2015
`
`2009 - 2015
`
`Other Appointments
`
`2005 - 2009
`
`2005 - 2009
`
`2004 - 2005
`
`2003 - 2004
`
`2001 - 2003
`
`Associate Chair for Undergraduate Studies, Georgia Institute of Technology,
`Biomedical Engineering, United States
`
`Professor, Georgia Institute of Technology, Biomedical Engineering, United
`States
`
`Associate Professor, The Ohio State University, Biomedical Engineering, United
`States
`
`Associate Professor (courtesy), The Ohio State University, Surgery, United
`States
`
`Associate Professor (courtesy), The Ohio State University, Physiology &
`Cell Biology, United States
`
`Associate Professor, Colorado State University, Mechanical Engineering,
`United States
`
`Associate Professor and Core Faculty Member, Colorado State University,
`School of Biomedical Engineering, United States
`
`Assistant Professor, Colorado State University, Mechanical Engineering,
`United States
`
`Assistant Professor and Core Faculty Member, Colorado State University,
`School of Biomedical Engineering, United States
`
`Research Engineer – I, Department of Biomedical Engineering, Georgia
`Institute of Technology, United States
`
`Gandy-Diaz Teaching Fellow (2006-2007) in the Department of Biomedical
`Engineering Georgia Institute of Technology, United States
`
`Postdoctoral Fellow, Department of Biomedical Engineering, Georgia Institute
`of Technology, United States
`
`Graduate Research Assistant, Department of Civil & Environmental
`Engineering, Georgia Institute of Technology, United States
`
`Graduate Teaching Assistant (CEE4200 Hydraulic Engineering 2001-2002;
`CEE6251 Fluid Mechanics Fall 2003; CEE6263 Fluid Mechanics of Organisms
`Fall 2002), Department of Civil & Environmental Engineering, Georgia
`Institute of Technology, United States
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`1999 - 2001
`
`1999 - 2001
`
`1999
`
`Degrees
`
`Tutor/Mentor at Office of Minority Education (OMED) Educational Services,
`Georgia Institute of Technology, United States
`
`Graduate Research Assistant, Department of Civil & Environmental
`Engineering, Georgia Institute of Technology, United States
`
`Library Shelver, Jacob Burns Law Library, George Washington University,
`United States
`
`August 2000 -
`December 2004
`
`
`
`January 1999 - July
`2000
`
`August 1994 - July
`1998
`
`PhD, Georgia Institute of Technology, Civil and Environmental Engineering.
`
`MS, Georgia Institute of Technology, Civil and Environmental Engineering.
`
`BTech, Indian Institute of Technology, Civil Engineering.
`
`Fellowships, Internships, Residency
`None
`
`Certifications
`
`July 2018
`
`
`
`Licensures
`None
`
`I-Corps@Ohio: Ohio Department of Higher Education
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`II. Core Dossier
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`Teaching
`1) Undergraduate, graduate, and professional courses taught
`
`Period Offered Course Number and Title
`(Credit Hours)
`
`Enr. % Taught,
`Role
`
`Stdnt
`Eval.
`
`Peer
`Eval.
`
`Other
`Eval.
`
`Instr.
`Method
`
`Autumn 2018
`
`BIOMEDE 4410 Biomechanics
`(3)
`
`15 100 Instructor Yes
`
`No
`
`No
`
`Spring 2018
`
`BIOMEDE 5194 Cardiovascular
`9
`Biofluid Mechanics (3)
`
`100 Instructor Yes
`
`Yes
`
`No
`
`Spring 2017
`
`Autumn 2016
`
`BIOMEDE 8811 Biomedical
`Engineering Seminars (1)
`
`BIOMEDE 8811 Biomedical
`Engineering Seminars (3)
`
`30 100 Instructor Yes
`
`No
`
`No
`
`34 100 Instructor Yes
`
`No
`
`No
`
`Autumn 2016
`
`BIOMEDE 4410 Biomechanics
`(3)
`
`34 100 Instructor Yes
`
`No
`
`No
`
`Spring 2016
`
`Spring 2015
`
`BIOMEDE 5194
`Cardiovascular Biofluid
`Mechanics (3)
`BIOM300 Problem Based
`Learning Lab (4)
`
`Spring 2015
`
`MECH539 Advanced Fluid
`Mechanics (3)
`
`Autumn 2014 MECH342 Mechanics and
`Thermodynamics of Flow
`Processes (Honors) (3)
`BIOM300 Problem Based
`Learning Lab (4)
`
`Spring 2014
`
`8
`
`100 Instructor Yes
`
`No
`
`No
`
`40 100 Instructor Yes
`
`No
`
`No
`
`21 100 Instructor Yes
`
`No
`
`No
`
`12 100 Instructor Yes
`
`No
`
`No
`
`21 100 Instructor Yes
`
`No
`
`No
`
`Spring 2014
`
`MECH539 Advanced Fluid
`Mechanics (3)
`
`22 100 Seminar
`Organizer
`
`Yes
`
`No
`
`No
`
`Spring 2013
`
`MECH539 Advanced Fluid
`Mechanics (3)
`
`11 100 Seminar
`Organizer
`
`Yes
`
`No
`
`No
`
`Spring 2013
`
`MECH342 Mechanics and
`Thermodynamics of Flow
`Processes (3)
`Autumn 2012 MECH338
`Thermodynamics Lab (1)
`
`55 100 Instructor Yes
`
`No
`
`No
`
`58 100 Seminar
`Organizer
`
`Yes
`
`No
`
`No
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Autumn 2012
`
`BIOM570 Bioengineering (3) 13 100 Seminar Yes
`
`No
`
`No
`
`Didactic /
`
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`Organizer
`
`Spring 2012
`
`Spring 2012
`
`BIOM581/MECH543
`Biofluid Mechanics (3)
`
`9
`
`100 Seminar
`Organizer
`
`Yes
`
`No
`
`No
`
`MECH539 Advanced Fluid
`Mechanics (3)
`
`18 100 Instructor Yes
`
`No
`
`No
`
`Autumn 2011 MECH342 Mechanics and
`Thermodynamics of Flow
`Processes (Honors) (3)
`Autumn 2011 MECH338
`Thermodynamics Lab (1)
`
`18 100 Instructor Yes
`
`No
`
`No
`
`33 100 Seminar
`Organizer
`
`Yes
`
`No
`
`No
`
`Autumn 2011
`
`BIOM570 Bioengineering
`(3)
`
`14 100 Seminar
`Organizer
`
`Yes
`
`No
`
`No
`
`Spring 2011
`
`Spring 2011
`
`MECH565 - Solar and
`Alternative Energies- 3
`Lectures only) (3)
`BIOM570 Bioengineering (3) 20 100 Instructor Yes
`
`13 100 Instructor Yes
`
`No
`
`No
`
`No
`
`No
`
`Autumn 2011 MECH342 Mechanics and
`Thermodynamics of Flow
`Processes (Honors) (3)
`Autumn 2010 MECH539 Advanced Fluid
`Mechanics (3)
`
`Spring 2010
`
`BIOM581/MECH543 Biofluid
`Mechanics (3)
`
`8
`
`9
`
`5
`
`100 Instructor Yes
`
`No
`
`No
`
`100 Instructor Yes
`
`No
`
`No
`
`100 Instructor Yes
`
`No
`
`No
`
`Spring 2010
`
`Summer 2009
`
`MECH342 Mechanics and
`Thermodynamics of Flow
`Processes (3)
`BMED1300 Problem Based
`Learning (3)
`
`Spring 2007
`
`BMED1300 Problem Based
`Learning
`
`Autumn 2006 BMED4757 Biofluid
`Mechanics (3)
`
`28 100 Instructor Yes
`
`No
`
`No
`
`12 100 Instructor Yes
`
`No
`
`No
`
`8
`
`100 Instructor Yes
`
`No
`
`No
`
`25 100 Instructor Yes
`
`No
`
`No
`
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`Didactic /
`Lecture
`
`2) Involvement in graduate/professional exams, theses, and dissertations, and undergraduate research
`
`
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`A major aspect of my academic duties is the advising of graduate and undergraduate students. Here the
`goal is the train students in the cutting edge areas of research while helping them to become potential
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`future leaders by developing their organization skills, communication skills, as well as independent thinking.
`My lab works as a focused group of students because the learning is more productive and insightful as a
`group, particularly one that is multi-cultural, international, and with minorities. There are roughly between
`six to eight graduate students in my group (on average) including international, minority, and non-
`traditional students. I believe that a group with such diverse backgrounds helps generate transformative
`ideas. We have structured weekly meetings to facilitate interaction, including a journal club in addition my
`student specific interactions catered for each student individually.
`
`At the Masters level, I have designed short research projects that a student can tackle within a 1-2 year time
`period. These projects help the student take their first independent research step by helping them formulate
`their own research topic as an original contribution and developing the appropriate experimental model. I
`strongly motivate students with the prospect of publishing their work and potentially continuing at the
`doctoral level or join Industry. I have advised a number of students both at CSU and OSU. These students
`work beside doctoral students and have been an integral part of my lab.
`
`Doctoral students have been at the heart of my lab who are a vibrant team of students who share the
`common passion of pursuing high-impact research in fluid mechanics and cardiovascular biomechanics.
`During the course of their training, students attend weekly meetings with me and bi-weekly meetings with
`our collaborators at the Wexner Medical Center Hospital or Nationwide Childrens or Colorado State
`University (via telecom) to discuss research progress. Together, these collaborators broaden students’
`knowledge as well as highlight the importance of teamwork and think more broadly. Regular group meetings
`are held where group members can interact, exchange ideas and brainstorm solutions to difficulties. These
`meetings train the students to think broadly, and sharpen their problem solving skills. Further, all students
`are involved in Journal club presentations, which are an exercise for my group members to develop the skills
`to critically analyze peer- reviewed technical papers by studying them with me. At the beginning of each
`semester, doctoral students are expected to develop a project plan with defined objectives, deadlines,
`deliverables and budget for that semester. At the end of the semester, student is expected to give a detailed
`presentation and written report on his/her accomplishments with a thorough self-assessment. As part of my
`training philosophy, a doctoral student is expected to publish at least three peer-reviewed publications in
`coveted journals. Students are encouraged and provided with opportunities to present his/her findings at
`national and international scientific meetings. These conferences allow students to interact with other
`researchers and further develop their skills to present / market his/her research findings. All of the writing
`and oral presentations help train my students in communication skills that are critical to their professional
`development and success. Doctoral students also have the opportunity to mentor undergraduate research
`assistants, so they will be ready to mentor students in their future academic career.
`
`.
`
`a) Graduate Students: Number Completed and Number Current
`
`Category
`
`Current Complete
`
`i) Doctoral Students (Dissertation Advisor)
`
`5
`
`5
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`ii) Doctoral Students (Dissertation Committee Member) 3
`
`5 (CSU)
`
`v) Master's Students Plan A (Thesis Advisor)
`
`vii) Master's Students (Thesis Committee Member)
`
`Totals
`
`0
`
`0
`
`8
`
`10
`
`5 (CSU)
`
`25
`
`i) Doctoral Students (Dissertation Advisor)
`
`2019 – Present Yeats B. Towards Patient Prosthetic Heart valves. The Ohio State University.
`
`2018 – Present Sivakumar S. Computational modeling of trans-catheter valves. The Ohio State
`University.
`
`
`2019 – Present Gooden S. Computational modeling of trans-catheter valves. The Ohio State
`University.
`
`2017 – Present Heitkemper M. Advanced flow controlled polymeric heart valves. The Ohio State
`University.
`2016 – Present Flemister D. 3D tissue engineered modeling of aortic valves. The Ohio State University.
`
`2015 - 2018
`
`Hatoum H. Fluid Mechanics of Transcatheter Aortic Valve Replacement. The Ohio
`State University. Current Positions: Postdoctoral Researcher
`
`2012 - 2015 Moore B. Regulation of Aortic Valve Sinus Hemodynamics by Anatomic Factors and Coronary
`Flow. Colorado State University. Graduated: 2015. Current Positions: Industry Researcher
`
`2010 - 2014
`
`Johnson B. Embryonic cardiac biomechanics and the role of mechanics on congenital
`defect formation. Colorado State University. Graduated: 2014. Current Positions:
`Industry Researcher
`
`2009 - 2014
`
`Forleo M. Time resolved particle image velocimetry analysis of bileaflet heart valves.
`Colorado State University. Graduated: 2014. Current Positions: Academic Researcher
`
`2010 - 2014 Morshed N. Phenomenology of anisotropic turbulence. Colorado State University.
`Graduated: 2014. Current Positions: Industry Researcher
`
`ii) Doctoral Students (Dissertation Committee Member)
`
`2019
`
`2018
`
`2018
`
`Farzadi A. The Ohio State University, Columbus, OH
`
`Rodriguez J. The Ohio State University, Columbus, OH
`
`Kanghyun K. The Ohio State University, Columbus, OH
`
`v) Master's Students Plan A (Thesis Advisor)
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`2017 - 2018
`
`2015 - 2018
`
`2014 - 2015
`
`2013 - 2015
`
`Shelley Gooden. In-vitro modeling of Mitra-clip repair for Mitral Regurgitation. The Ohio
`State University.
`2017 - 2018 Michael Mastran. Trileaflet Mechanical Heart Valve Prosthesis. The Ohio State
`University.
`Amir Azimian. Computational modeling of trans-catheter heart valve therapy. The Ohio
`State University. Graduated: 2018.
`Ryan Oba. Development of bioreactor for aortic valve mechanobiology. The Ohio State
`University. Graduated: 2018.
`Banefshah Zebhi. Hemodynamic and anatomic correlates of calcific aortic valve disease:
`image based analysis of lesions. Colorado State University. Graduated: 2015.
`Alexander Bulk. Embryonic cardiovascular biomechanics. Colorado State University.
`Graduated: 2015.
`Evan Koenig. In-vitro study of trans-catheter mitral valve prosthesis. Colorado State
`University. Graduated: 2014.
`Haiming Tan. Lumped parameter modeling of multiple heart valve disease and cardiac
`energetics. Colorado State University. Graduated: 2013.
`Canek Philips. A simple lumped parameter model of the cardiovascular system. Colorado
`State University. Graduated: 2011.
`Brandon Moore. Effects of structure on flow mechanics in the human left ventricle and
`respiratory tract. Colorado State University. Graduated: 2011.
`Kevin Migita. Design and fabrication of a flow chamber for the study of cell adhesion and
`hemocompatibilty in dynamic conditions. Colorado State University. Graduated: 2011.
`Jennifer Serrao. Colorado State University. Graduated: 2010.
`
`2013 - 2014
`
`2011 - 2013
`
`2009 - 2011
`
`2009 - 2011
`
`2009 - 2011
`
`2009 - 2011
`
`2009 - 2010
`
`
`
`vi) Undergraduate Student Advising
`
`2018 - 2018
`
`2017 - 2019
`2017 - 2018
`2015 - 2018
`
`2014 - 2015
`
`2013 - 2015
`
`2013 - 2014
`
`2011 - 2013
`
`2009 - 2011
`
`2009 - 2011
`
`2009 - 2011
`
`2009 - 2011
`
`Breandon Yeats – Developing computational models for heart valve engineering. The
`Ohio State University.
`Tori Burton – Developing polymeric heart valves. The Ohio State University.
`Kunal Gupta – Processing patient CT angiography data. The Ohio State University.
`Ian May – Statistical analysis the small scale structure of fluid turbulence. Colorado State
`University.
`Hannah Mikelson – Developing electrical impedance tomography device specifically for
`aortic valve imaging. Colorado State University.
`Lane Taylor – Prosthetic heart valve design and energy loss characterization Colorado
`State University.
`Joslyne Lovelace – Nitinol Stents for transcatheter aortic valves. Colorado State
`University.
`Jennifer Vaughn – Developing a Novel Low Cost Heart Valve Fatigue Tester – Honors
`Thesis May 2013. Colorado State University.
`Evan Siebenmorgen – Modeling calcific aortic valve ideas in fresh pig hearts. Colorado
`State University.
`Rachael Simon, Denver Metropolitan, Undergraduate American Heart Association Fellow.
`Colorado State University.
`Eric Dishinger – Honors Thesis in Mechanical Engineering. Colorado State University.
`Graduated: 2011.
`Stephanie Jebsen – Development of a beating cadaver heart simulator. Colorado State
`University
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`b) Describe any noteworthy accomplishments of graduate students for whom you have been the
`advisor of record, for example, publications during or emanating from graduate program, awards for
`graduate work, prestigious post-docs or first post-graduate positions.
`I have graduated a total of five doctoral students. All of the doctoral students have been first authors in
`conference and journal publications since 2011. Megan Heitkemper received the ICorps Ohio grant as
`Entrepreneurial Lead. Hoda Hatoum received the prestigious Presidential Graduate Fellowship and has
`published over 20 first authored papers. Hoda Hatoum received the BMES Early Career Development
`Award for the 2019 meeting. Megan Heitkemper received the Diversity Travel award to present at the
`2018 World Congress of Biomechanics, Dublin Ireland, while Dormal Flemister and Hoda Hatoum were
`runners-up (towards being finalistics) in the PhD student paper competition at the same meeting. Dorma
`Flemester also received the diversity travel award to present at the 2017 SB3C (Summer Biomechanics,
`Bioengineering, and Biotransport Conference) in Tuson, Arizona. Marcio Forleo won the NSF AGEP
`minority fellowship award and is now currently industry researcher at Gore Biomedical Inc. Brandon
`Moore received the best teaching assistant award at Colorado State University.
`
`
`
`
`
`c) Undergraduate Research Mentoring
`I have always served as undergraduate research mentor since 2009. Undergrads bring highly enthusiastic
`energy into the lab and are the ideal people to undertake risky and high reward research activities. I usually
`recruit these students through senior design teams or through the undergraduate classes that I teach.
`Some of my undergraduate research students have presented at national conferences
`
`
`
`
`
`d) Describe any noteworthy accomplishments of undergraduate students, in particular related to
`research, for whom you have been the advisor of record (publications, posters, honors or student
`awards).
`Rachael Simon was an undergrad from Denver Metropolitan, who won the Undergraduate American Heart
`Association Fellow twice in Summer 2012 and 2013. Ian May presented an oral talk at the American
`Physical Society (Division of Fluid Dynamics) conference on turbulent flows in 2014. Melody Dong (a high-
`school student) presented a poster at the American Physical Society (Division of Fluid Dynamics). Rachael
`Simon presented a poster at the American Society of Mechanical Engineers annual meeting in 2012. In
`2019, Tori Burton won 2nd place in the undergraduate poster competition at SB3C 2019.
`
`3) Involvement with Posdoctoral Scholars and Researchers
`I have been involved in the advising of five postdocs.
`
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`1.
`
`Dr. Hieu Bieu (PhD) (8/2019-present) – Studying advanced biomaterials on prosthetic heart valves.
`
`Dr. Hoda Hatoum (PhD) (9/2018-8.2019) – Studying superhydrophobic and vortex generator
`2.
`controlled heart valves.
`
`Dr. David Bark (PhD) (11/2013-8/2015) – Studying prosthetic heart valve design parameters and
`3.
`hemodynamics in relation to fatigue and thrombosis characteristics. Currently Assistant Professor at
`Colorado State University.
`
`Dr. Marcio Forleo (PhD) 8/2014-12/2014 – Assisting in particle image velocimetry studies for textile
`4.
`and polymeric heart valves. Currently Industry researcher.
`
`Dr. Neil Stafford (MD) (1/2013-5/2014) – Embryonic cardiac biomechanics and the role of mechanics
`5.
`on congenital defect formation. Currently Assistant Professor (Clinical) at Duke University.
`
`Dr. Pablo Maureira (MD/PhD) (11/2013-7/2014) – Studying transcatheter aortic and mitral valve
`6.
`replacement devices. Currently Department Chair of Cardiac Surgery in University Hospital of Nancy, France.
`
`
`
`Postdocs are involved with the future research direction of the lab by being involved in grant proposal writing
`as well as new research study designs. They also help mentor all graduate students in the lab by being positive
`role models as well as by being involved in day to day research tasks. In addition, postdocs also undergo the
`same training as with doctoral students with respect to meetings, journal clubs, and the expectation of
`semester plans and progress reports. Postdocs are encouraged to attend workshops at the university level
`for grant writing and also attend faculty candidate workshops at national meetings.
`
`
`
`
`
`4) Extension and Continuing Education Instruction
`None.
`
`5) Curriculum Development
`
`At OSU/CSU, I developed two graduate courses and one undergraduate course. The graduate courses are
`Advanced Fluid Mechanics, and Cardiovascular Biofluid Mechanics. The fluids course is a core course for
`the MS and PhD programs that mechanical engineering graduate students may take. The biofluids course
`is a technical elective course open to biomedical and mechanical/chemical engineering students. Both of
`these courses provide students with advanced knowledge in fluid mechanics and biofluid mechanics while
`maintaining an introductory style, thus building and reinforcing fundamental principles at an advanced
`level. In addition to these two graduate courses, I developed a new undergraduate course to support the
`creation of the new undergraduate biomedical engineering dual degree program at CSU. This course is
`BIOM300 – Problem based learning laboratory, a 4-credit required lab course for all dual degree
`biomedical engineering students. The novel aspect of this course is its non-didactic style to inculcate the
`core biomedical engineering experience of “multi-disciplinary problem solving” in the context of health
`care. The course achieves this through a series of open-ended biomedical engineering problems that
`require students to perform inquiry, hypothesis development, experimental design, data analysis, and
`
`Dasi - Page 13 of 58
`
`Colibri Heart Valve LLC, Exhibit 2027, Page 13 of 65
`
`

`

`communication of results as a team. Through this process, the students learn to appreciate true teamwork
`while exposing themselves to advanced topics in biomedical engineering – including biomechanics,
`imaging, exercise physiology, and medical devices.
`
`
`
`6) Brief Description of your approach to and goals in teaching, major accomplishments, plans for the
`future in teaching
`Teaching and mentoring has been the most rewarding aspect of my duties as a faculty member at Ohio State
`University (OSU) and Colorado State University (CSU). It is an honor and great privilege to shape future minds,
`each inherently unique. Since starting as a faculty member, I have been the primary instructor for 6 courses -
`2 graduate and 4 undergraduate levels, and I have helped co-teach 2 additional graduate courses. I also
`regularly participate in the senior design capstone courses in mechanical and biomedical engineering. I have
`found that these teaching/mentoring activities truly push my own knowledge about the course material and
`these activities further strengthen my passion for academia. This has been particularly true for the three new
`courses that I have had the privilege to develop. These experiences have fundamentally changed the way I
`see “teaching” in comparison to what I believed prior to becoming a professor. I now appreciate that
`successful teaching involves much more than just “lecturing”. Rather, it actively involves the establishment of
`a low level connection with students, which then dictates the manner in which high level knowledge must be
`broken down and presented. This is a dynamic process and every class (even for the same course) is different.
`In essence, the connection must be optimal to maximize the absorption of knowledge. This process defines
`my teaching strategy that can be simplistically represented as: (a) continuously excite the students about the
`subject matter through the significance of the knowledge and its intellectual appeal, (b) provide the
`fundamental principles in the most general form, yet in an applicable manner that any engineering student
`can master, and (c) challenge the minds to the highest level requiring true independent thought and mastery
`in the application of fundamental principles. This simple strategy truly represents my classroom teaching
`philosophy, which I believe strongly and positively impacts student learning objectives.
`
`Outside of the classroom, I strongly believe in the concept of a capstone senior design experience in
`biomedical engineering. Over the past five years, I have sponsored and challenged groups of seniors to address
`a variety of engineering problems related to state-of-the-art cardiovascular bioengineering design problems
`on prosthetic heart valves, left heart simulators, and minimally invasive cardiovascular surgical tools. These
`mentoring experiences were highly successful in generating a high level of intellectual challenge for budding
`engineers as well as advancing research in these areas. Most of these senior design products proved to be
`valuable proof-of-concept experiments for my successful grants and are still used in the lab to-date.
`
`Overall, I love teaching and I have had a truly awesome and rewarding experience. I look forward to further
`evolving my classes towards the highest quality.
`
`7) Evaluation of Teaching
`In our department, the teaching is evaluated through Student Evaluation of Intructors (SEI), Qualtrics
`student survey, and peer evaluations provided by colleague. Our department maintains the CQI
`(Continuous Quality Improvement) table for each and every course. After every semester, I participate in
`the self-assessment of the course and update the CQI table for future offerings. I have always taken into
`Dasi - Page 14 of 58
`
`Colibri Heart Valve LLC, Exhibit 2027, Page 14 of 65
`
`

`

`account comments from students and colleagues and continuously improved my teaching. At CSU as well
`as at OSU, my SEI scores (item 10) have either met or exceeded college metrics or has been the best SEI
`score for that course in our department. To help students who struggle with equation/math aspects of
`biomedical engineering, I offer more one-on-one time with students outside of office hours as well as
`incorporated more problem solving in class sessions. This helps the student learn as well as appreciate their
`own limitations better.
`
`8) Awards and Formal Recognition for Teaching
`2020, ABME Best Paper Award “Sinus Hemodynamics Variation with Tilted Transcatheter Aortic Valve
`Deployments paper”.
`2017, Melissa G. Piper Distinguished Mentor Award, Dorothy M. Davis Heart & Lung Research Institute, The
`Ohio State University, Columbus OH, USA.
`2015, Nominated for Best Professor Award - Edays, College of Engineering, Colorado State University, Fort
`Collins CO, USA.
`2014, George T. Abell Outstanding Teaching & Service Faculty Award, College of Engineering, Colorado State
`University, Fort Collins CO, USA.
`2011, Nominated for the Best Teacher Award at the University Level, Colorado State University.
`2006, Teaching Fellowship Award, School of Biomedical Engineering, Georgia Institute of Technology,
`Atlanta GA, USA.
`2002, Outstanding Teaching Assistant Award, Civil and Environmental Engineering, Georgia Institute of
`Technology, Atlanta GA, USA.
`
`9) Other Academic Advising
`I frequently recruit and advise high-school students as well as minority students from the community. I am
`also involved in advising MD fellows at Nationwide Children through my involvement in a Cardiovascular T32
`grant at Nationwide (PI: Vidu Garg). I also participate as mentor to students as well as junior faculty at various
`national meeting mentoring workshops.
`
`10) Teaching Professional Development
`
`I attended teaching workshops at Georgia Institute of Technology on developing the “Problem Based
`Learning” concept. I also attended University teaching center workshops at Colorado State University as
`an Assistant Professor

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