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`ABOUT US
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`M I- U NO M WEe xe m
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`OCTOBER 27, 2020
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`June 11, 2020 / 0
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`University of Colorado a global leader in
`patents for inventions, innovations
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`CU leaps into Top 20 universities for connecting research and industry
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`By Staff // Issue: June 11, 2020 // Categories: CU Boulder, UCCS, CU Denver, CU Anschutz Medical
`Campus, CU South Denver, CU System, Faculty, Staff
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`Patent Owner Ex. 2008-0001
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`The University of Colorado jumped from No. 53 to No. 20 in a recent global ranking of the top 100
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`universities granted U.S. utility patents for an array of inventions and innovations that can have far-
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`reaching and positive impacts on society.
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`The National Academy of Inventors (NAI) and the Intellectual Property Owners Association (IPO)
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`this week announced the 2019 rankings. All four campuses contributed to CU's total 100 patents.
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`"This is yet another demonstration of the innovative, entrepreneurial spirit of faculty across the CU
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`system," said CU President Mark Kennedy. "Our faculty improve lives, save lives and make our
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`state and world a better place. I'm pleased and proud that CU faculty are so adept at securing
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`patents that turn their ideas and research into practical applications that advance a variety of fields."
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`Here are the highest-impact patents from 2019 and their associated university spinoffs:
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`• Inscripta — After raising $260M in investment capital, Inscripta brought the breakthrough
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`digital engineering platform Onyx to market. Inscripta was founded on an exclusive license to
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`a portfolio of CU patents, including US 10,266,849 "CRISPR enabled multiplexed genome
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`engineering" invented by CU Boulder chemical and biological engineering associate professor
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`Ryan Gill. The innovation developed in the Gill lab, known as "CREATE," enables rapid,
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`multiplexed editing at multiple locations across the genome.
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`• Kahook Dual Blade - US 10,327,947 "Modified Dual-Blade Cutting System," was created by
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`Malik Kahook, M.D., CU School of Medicine professor in ophthalmology at the CU Anschutz
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`Patent Owner Ex. 2008-0002
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`Medical Campus. The Kahook Dual Blade, launched in 2015 by New World Medical, is a novel
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`surgical blade created to produce a more complete removal of trabecular meshwork, which is
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`the eye tissue associated with the development of glaucoma. Glaucoma is a leading cause of
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`irreversible blindness around the globe. Surgery with the Kahook Dual Blade is minimally
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`invasive and can be effectively performed with equal efficacy in modern operating rooms as
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`well as in low-resource areas around the world. It is now one of the most commonly performed
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`glaucoma procedures and backed by extensive evidence-based medicine.
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`• Stateless — Stateless, a company reinventing network connectivity, is the exclusive licensee
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`of US 10,245,348 "Stateless Network Functions." This technology enables new levels of
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`automation, greatly simplifies how businesses access remote IT services and uses computing
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`resources more than five times more cost-effectively than traditional approaches. Lead
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`inventors Eric Keller, a CU Boulder associate professor in electrical, computer and energy
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`engineering, and Murad Kablan (PhDCompSci'17) co-founded Stateless after completing CU
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`Boulder's New Venture Challenge and Catalyze CU accelerator.
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`• Q32 Bio — US 10,233,235 "Modulating the Alternative Complement Pathway" application
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`pertains to methods and compositions for modulating, e.g., stimulating or inhibiting, activity of
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`the alternative complement pathway. This therapeutic approach is important because it
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`provides targeted regulation of complement directly in diseased tissues while minimizing the
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`risk of serious infections and other complications associated with systemic complement
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`pathway modulation. The patent is licensed to Q32 Bio, a biotechnology company developing
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`treatments for patients with severe autoimmune and inflammatory diseases. Q32 Bio was
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`seeded and incubated by Atlas Venture with foundational science from renowned researchers
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`in immunology Michael Holers, M.D., and Joshua Thurman, M.D., from the CU School of
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`Medicine at the CU Anschutz Medical Campus. The company raised $46 million in Series A
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`funding and expects to enter into a Phase I trial in 2021.
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`• Longpath Technologies —US 10,240,998 "Determining a Location and Size of a Gas
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`Source with a Spectrometer Gas Monitor" was created by lead inventor and Longpath co-
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`founder Greg Rieker, a CU Boulder associate professor in mechanical engineering. Rieker, in
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`collaboration with colleagues at CU Boulder and NIST, applied Nobel Prize-winning research
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`on optical frequency combs to detect trace gases with extraordinary sensitivity. LongPath is
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`commercializing cost-effective, continuous gas leak detection and preparing for commercial
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`deployments starting in summer 2020. Rieker also placed first in the 2017 Lab Venture
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`Challenge.
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`Patent Owner Ex. 2008-0003
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`"While patents are a critical part of commercialization, our strategy also heavily emphasizes
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`entrepreneurial training, mentorship and startup resources," said Brynmor Rees, assistant vice
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`chancellor for Research & Innovation at CU Boulder and managing director of Venture Partners at
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`CU Boulder. "This jump in our ranking shows that our engine of new innovations powers our holistic
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`approach of bringing ideas to market."
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`"The University of Colorado's focus on innovation is yielding impressive results, and we continue to
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`see forward momentum," said Donald M. Elliman Jr., chancellor of the University of Colorado
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`Anschutz Medical Campus. "At CU Anschutz, our CU Innovations team embodies our collaborative
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`spirit by connecting industry partners with our physicians and researchers in partnerships that lead
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`to diverse projects spanning biomedical technology, novel therapeutics and medical devices. That
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`creative collaboration had led to an increase in patent applications, and growing recognition of our
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`campus as a dynamic hub for commercial innovations that are transforming health care and saving
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`lives."
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`The report uses data obtained from the U.S. Patent and Trademark Office (USPTO) and highlights
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`the vital role patents play in university research and innovation.
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`Published annually since 2013, the report ranks the top 100 universities named as first assignee on
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`utility patents granted by the USPTO in the 2019 calendar year.
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`"The institutions included in this year's report are leading innovation worldwide through their
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`encouragement of academic discovery and invention," said Paul R. Sanberg, NAI president. "We
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`are proud to collaborate with the IPO for the eighth consecutive year to highlight universities that
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`have made critical contributions to society."
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`There are 57 member institutions of the NAI represented this year in the Top 100. They hold an
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`aggregate total of 4,685 patents spanning a wide variety of fields, such as medicine, technology and
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`engineering. The IPO Top 300 Patent Owners List, published annually since 1985, ranks
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`organizations worldwide that received the most U.S. utility patents during the previous calendar
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`year.
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`This year's report on 2019 patents, published May 18, lists the total number of patents for 2019's
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`Top 100 universities (including U.S. and international universities) to be 7,873, an increase of 1,046
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`patents over the previous year.
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`Patent Owner Ex. 2008-0004
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`"University patents ignite a culture of growth and innovation which in turn stimulates the economy,"
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`said Jessica Landacre, IPO executive director. "The Top 100 Worldwide Universities Granted U.S.
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`Utility Patents demonstrates which institutions excel in this arena."
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`Read the full report.
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`Tagged with: research, patents, Office of Technology Transfer
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`Patent Owner Ex. 2008-0005
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