`
`On behalf of Illumina, Inc.
`By: Kerry S. Taylor
`
`Nathanael R. Luman
`Michael L. Fuller
`William R. Zimmerman (pro hac vice)
`KNOBBE, MARTENS, OLSON & BEAR, LLP
`2040 Main Street, 14th Floor
`Irvine, CA 92614
`Fax: (858) 707-4001
`Tel.: (858) 707-4000
`Email: BoxIllumina@knobbe.com
`
`
`
`
`
`
`
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`__________________________________
`
`BEFORE THE PATENT TRIAL AND APPEAL BOARD
`__________________________________
`
`ILLUMINA, INC.
`Petitioner,
`
`v.
`
`TRUSTEES OF COLUMBIA UNIVERSITY
`IN THE CITY OF NEW YORK
`Patent Owner.
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`IPR2020-01177
`Patent 10,435,742
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`ILLUMINA UPDATED EXHIBIT LIST
`
`
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`
`
`Pursuant to 37 C.F.R. § 42.63(e), Petitioner Illumina, Inc. (“Illumina”)
`
`hereby provides an updated list of its exhibits in this proceeding.
`
`Exhibit
`No.
`
`EXHIBIT LIST
`
`Description
`
`1001
`
`U.S. Patent No. 10,407,458 (“Ju”) – (guanine with allyl proviso)
`
`1002
`
`U.S. Patent No. 10,407,459 (“Ju”) – (adenine with allyl proviso)
`
`1003
`
`U.S. Patent No. 10,457,984 (“Ju”) – (cytosine with allyl proviso)
`
`1004
`
`U.S. Patent No. 10,435,742 (“Ju”) – (thymine with allyl proviso)
`
`Exhibit numbers 1005-1012 not used.
`
`1013
`
`U.S. Patent No. 7,790,869 (“Ju”)
`
`1014
`
`U.S. Patent No. 7,713,698 (“Ju”)
`
`1015
`
`U.S. Patent No. 8,088,575 (“Ju”)
`
`1016
`
`U.S. Patent No. 9,718,852 (“Ju”) – (adenine)
`
`1017
`
`U.S. Patent No. 9,719,139 (“Ju”) – (thymine)
`
`1018
`
`U.S. Patent No. 9,708,358 (“Ju”) – (cytosine)
`
`1019
`
`U.S. Patent No. 9,725,480 (“Ju”) – (guanine)
`
`1020
`
`U.S. Patent No. 9,868,985 (“Ju”) – (method)
`
`1021
`
`2014-03-06 IPR2012-00007, Paper 140, Final Written Decision
`
`1022
`
`2014-03-06 IPR2012-00006, Paper 128, Final Written Decision
`
`1023
`
`2014-03-06 IPR2013-00011, Paper 130, Final Written Decision
`
`1024
`
`2019-06-21 IPR2018-00291, -00318, -00322, -00385, Final Written
`Decisions
`
`- 1 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`Description
`
`Exhibit numbers 1025-1027 not used.
`
`1028
`
`2019-09-09 IPR2018-00797, Final Written Decision
`
`1029
`
`2015-07-17 Federal Circuit Opinion Affirming IPR2012-00006,
`IPR2012-00007 and IPR2013-00011
`
`1030
`
`U.S. Patent No. 5,547,839 (“Dower”)
`
`1031 WO 91/06678 (“Tsien”)
`
`1032
`
`Exhibit number not used
`
`1033
`
`Welch et al., “Syntheses of Nucleosides Designed for Combinatorial
`DNA Sequencing,” Chem. Eur. J., 5:951-960 (1999) (“Welch”)
`
`Exhibit numbers 1034-1036 not used.
`
`1037
`
`Alberts et al., “Molecular Biology of the Cell,” Third Edition, Garland
`Publishing Inc., New York (1994)
`
`1038
`
`Exhibit number not used
`
`1039
`
`Metzker et al., “Termination of DNA synthesis by novel 3’-modified-
`deoxyribonucleoside 5’-triphosphates,” Nucleic Acids Research,
`22:4259-67 (1994) (“Metzker”)
`
`1040
`
`Sanger et al., “DNA sequencing with chain-terminating inhibitors,”
`Proc. Nat’l Acad. Sci. USA, 74:5463-5467 (1977) (“Sanger”)
`
`1041
`
`Prober et al., “A System for Rapid DNA Sequencing with Fluorescent
`Chain-Terminating Dideoxynucleotides,” Science, 238:336-341 (1987)
`(“Prober”)
`
`1042
`
`U.S. Patent No. 5,302,509 (“Cheeseman”)
`
`1043
`
`U.S. Patent No. 5,763,594 (“Hiatt”)
`
`- 2 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`1044
`
`Description
`
`Pelletier et al., “Structures of Ternary Complexes of Rat DNA
`Polymerase β, a DNA Template-Primer, and ddCTP,” Science,
`264:1891-1903 (1994) (“Pelletier”)
`
`1045
`
`Exhibit number not used
`
`1046
`
`Rosenblum et al., “New dye-labeled terminators for improved DNA
`sequencing patterns,” Nucleic Acid Research, 25:4500-4504 (1997)
`(“Rosenblum”)
`
`1047
`
`Exhibit number not used
`
`1048
`
`1049
`
`1050
`
`Excerpts from 2019-01-14 Deposition Transcript of Dr. Menchen in
`IPR2018-00291, -00318, -00322, and -00797
`
`2018-05-04 IPR2018-00385, Paper 13, Patent Owner Preliminary
`Response
`
`Canard et al., “Catalytic editing properties of DNA polymerases,” Proc.
`Nat’l Acad. Sci. USA, 92:10859-10863 (1995) (“Canard”)
`
`1051
`
`Exhibit number not used
`
`1052
`
`Yu et al., “Cyanine dye dUTP analogs for enzymatic labeling of DNA
`probes,” Nucleic Acids Research, 22:3226-3232 (1994) (“Yu”)
`
`1053
`
`Livak et al., “Detection of single base differences using biotinylated
`nucleotides with very long linker arms,” Nucleic Acids Research,
`20:4831-4837 (1992) (“Livak”)
`
`1054
`
`Stryer, “Biochemistry,” Fourth Edition, W.H. Freeman and Co., New
`York (1995) (“Stryer”)
`
`1055
`
`Watson & Crick, “Genetical Implication of the Structure of
`Deoxyribonucleic Acid,” Nature, 171:964-967 (1953) (“Watson &
`Crick”)
`
`1056
`
`U.S. Patent No. 5,151,507 (“Hobbs”)
`
`- 3 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`Description
`
`1057
`
`Exhibit number not used
`
`1058
`
`Excerpts from Sept. 4-5, 2013 Deposition Transcript of Dr. George L.
`Trainor in IPR2012-00007
`
`1059
`
`Exhibit number not used
`
`1060
`
`Hovinen et al., “Synthesis of 3´-O-(ω-Aminoalkoxymethyl)thymidine
`5´-Triphosphates, Terminators of DNA Synthesis that Enable 3’-
`Labeling,” J. Chem. Soc. Perkin Trans. 1, 211-217 (1994) (“Hovinen”)
`
`1061
`
`Exhibit number not used
`
`1062
`
`Excerpt from Prosecution History of U.S. Patent No. 9,725,480
`
`1063
`
`Ireland et al., “Approach to the Total Synthesis of Chlorothricolide:
`Synthesis of (±)-19,20-Dihydro-24-O-methylchlorothricolide, Methyl
`Ester, Ethyl Carbonate,” J. Org. Chem. 51:635-648 (1986) (“Ireland”)
`
`1064
`
`Exhibit number not used
`
`1065
`
`Excerpt from Prosecution History of U.S. Patent No. 10,428,380 [U.S.
`Appl. No. 16/150,191] (2019-03-12 Pre-interview first office action)
`
`1066
`
`1067
`
`Ruparel et al., “Design and synthesis of a 3´-O-allyl photocleavable
`fluorescent nucleotide as a reversible terminator for DNA sequencing
`by synthesis,” PNAS, Vol. 102, No. 17, 5932-37 (2005) (“Ruparel”)
`
`Ju et al., “Four-color DNA sequencing by synthesis using cleavable
`fluorescent nucleotide reversible terminators,” PNAS, Vol. 103, No.
`52, 19635-40 (2006) (“Ju”)
`
`1068
`
`2015-02-11 IPR2013-00517, Paper 87, Final Written Decision
`
`1069
`
`2016-05-09 Federal Circuit Opinion Affirming IPR2013-00517
`
`1070
`
`U.S. Patent No. 5,449,767 (“Ward”)
`
`1071
`
`Exhibit number not used
`
`- 4 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`Description
`
`1072 WO 98/33939 (“Anazawa”)
`
`1073
`
`Anazawa (English Translation of WO 98/33939)
`
`1074
`
`Exhibit number not used
`
`1075
`
`PROTECTIVE GROUPS IN ORGANIC SYNTHESIS (Theodora W.
`Greene & Peter G.M. Wuts eds., 3rd ed. 1999) (excerpts) (“Greene &
`Wuts”)
`
`1076
`
`Boss et al., “Cleavage of Allyl Ethers with Pd/C,” Angew. Chem. Int.
`Ed. Engl., 15:558-559 (1976) (“Boss”)
`
`1077
`
`1078
`
`Qian et al., “Unexpected Enzymatic Fucosylation of the Hindered
`Tertiary Alcohol of 3-C-Methyl-N-Acetyllactosamine Produces a
`Novel Analogue of the LeX-Trisaccharide,” J. Am. Chem. Soc.,
`120:2184-2185 (1998) (“Qian”)
`
`Kamal et al., “A Mild and Rapid Regeneration of Alcohols from their
`Allylic Ethers by Chlorotrimethylsilane/Sodium Iodide,” Tetrahedron
`Letters, 40:371-372 (1999) (“Kamal”)
`
`1079
`
`2014-07-25 Final Written Decision in IPR2013-00128, Paper 92
`
`1080
`
`2014-10-28 Final Written Decision in IPR2013-00266, Paper 73
`
`1081
`
`2016-01-29 Federal Circuit Opinion Affirming IPR2013-00128 and
`IPR2013-00266
`
`1082
`
`IPR2017-02172, Paper 20 (P.T.A.B. 2018)
`
`1083
`
`IPR2017-02174, Paper 20 (P.T.A.B. 2018)
`
`1084
`
`Meng et al., “Design and Synthesis of a Photocleavable Fluorescent
`Nucleotide 3´-O-Allyl-dGTP-PC-Bodipy-FL-510 as a Reversible
`Terminator for DNA Sequencing by Synthesis,” J. Org. Chem. 71,
`3248-3252 (2006) (“Meng”)
`
`- 5 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`1085
`
`Description
`
`Bi et al., “Design and Synthesis of a Chemically Cleavable Fluorescent
`Nucleotide, 3´-O-Allyl-dGTP-allyl-Bodipy-FL-510, as a Reversible
`Terminator for DNA Sequencing by Synthesis,” J. Am. Chem. Soc.,
`128, 2542-2543 (2006) (“Bi”)
`
`1086
`
`Meng thesis from Dr. Ju’s laboratory at Columbia University (2006)
`(“Meng Thesis”)
`
`1087
`
`1088
`
`1089
`
`1090
`
`1091
`
`1092
`
`1093
`
`1094
`
`Wu, et al., “3´-O-modified nucleotides as reversible terminators for
`pyrosequencing,” PNAS, Vol. 104, No. 42, 16462-16467 (2007)
`(“Wu”)
`
`Kim thesis from Dr. Ju’s laboratory at Columbia University (2008)
`(“Kim Thesis”)
`
`Wu thesis from Dr. Ju’s laboratory at Columbia University (2008)
`(“Wu Thesis”)
`
`Zhang thesis from Dr. Ju’s laboratory at Columbia University (2008)
`(“Zhang Thesis”)
`
`Guo et al., “Four-color DNA sequencing with 3´-O-modified
`nucleotide reversible terminators and chemically cleavable fluorescent
`dideoxynucleotides,” PNAS, Vol. 105, No. 27, 9145-9150 (2008)
`(“Guo”)
`
`Guo thesis from Dr. Ju’s laboratory at Columbia University (2009)
`(“Guo Thesis”)
`
`Yu thesis from Dr. Ju’s laboratory at Columbia University (2010) (“Yu
`Thesis”)
`
`Qui thesis from Dr. Ju’s laboratory at Columbia University (2011)
`(“Qui Thesis”)
`
`1095
`
`Exhibit number not used
`
`1096
`
`Lipshutz et al., “Hydrolysis of Acetals and Ketals Using LiBF4,”
`Synthetic Communications, 12:4, 267-277 (1982)
`
`- 6 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`Description
`
`1097
`
`Curriculum Vitae of Floyd Romesberg, Ph.D.
`
`1098
`
`Exhibit number not used
`
`1099
`
`U.S. Patent No. 7,270,951 (“Stemple”)
`
`1100
`
`Kraevskii et al., Molecular Biology 21:25-29 (1987) (“Kraevskii”)
`
`Exhibit numbers 1101-1103 not used.
`
`Seitz et al., HYCRON, an Allylic Anchor for High-Efficiency Solid
`Phase Synthesis of Protected Peptides and Glycopeptides,” J. Org.
`Chem., 62:813-826 (1997) (“Seitz”)
`
`Greenberg et al., “Optimization and Mechanistic Analysis of
`Oligonucleotide Cleavage from Palladium-Labile Solid-Phase
`Synthesis Supports,” J. Org. Chem., 63:4062-4068 (1998)
`(“Greenberg”)
`
`Gullier et al., “Linkers and Cleavage Strategies in Solid-Phase Organic
`Synthesis and Combinatorial Chemistry,” Chem. Rev., 100:2091-2157
`(2000) (“Guillier Review 2000”)
`
`Fields, Methods in Molecular Biology, Volume 35, Peptide Synthesis
`Protocols, Chapter 2, Humana Press 1994 (“Fields”)
`
`Gigg et al., “The Allyl Ether as a Protecting Group in Carbohydrate
`Chemistry Part II”, J. Chem. Soc. (C), 1903-1911 (1968) (“Gigg”)
`
`IUPAC, Nomenclature of Organic Chemistry, Eds. Rigaudy et al.,
`International Union of Pure and Applied Chemistry, Organic Chemistry
`Division, Commission on Nomenclature of Organic Chemistry,
`Pergamon Press, 1979.
`
`CRC Handbook of Chemistry and Physics, eds. Weast et al., 72nd
`edition, CRC Press (1991)
`
`McGraw-Hill Dictionary of Chemistry, ed. Parker, McGraw-Hill Book
`Co., 1984
`
`1104
`
`1105
`
`1106
`
`1107
`
`1108
`
`1109
`
`1110
`
`1111
`
`- 7 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`1112
`
`1113
`
`1114
`
`1115
`
`Description
`
`Vollhardt et al., “Organic Chemistry,” W.H. Freeman and Co., New
`York (2d ed. 1994) (“Vollhardt”)
`
`Solomons, “Organic Chemistry”, Fourth Edition, John Wiley & Sons
`(1988) (“Solomons”)
`
`Morrison et al., “Organic Chemistry,” Third Edition, Allyn and Bacon,
`Inc. (1973)
`
`Dominguez et al., “DNA polymerase mu (Pol μ), homologous to TdT,
`could act as a DNA mutator in eukaryotic cells,” The EMBO Journal,
`19(7): 1731-1742 (2000) (“Dominguez”)
`
`1116
`
`Ito et al., “Compilation and alignment of DNA polymerase sequences,”
`Nucleic Acids Research, 19: 4045-4057 (1991) (“Ito”)
`
`1117
`
`1118
`
`1119
`
`1120
`
`1121
`
`Collins et al., “A rapid method for mRNA detection in single-cell
`Biopsies from preimplantation-stage bovine embryos,”
`Theriogenology, 43: 1227-1238 (1995) (“Collins”)
`
`Haber et al., “Diagnosis of Flame Chlorosis by Reverse Transcription–
`Polymerase Chain Reaction (RT-PCR),” Plant Disease, 79(6): 626-630
`(1995) (“Haber”)
`
`Sidorova et al., “A rapid RT-PCR based method for the detection of
`BCR-ABL translocation,” J. Clin Pathol: Mol Pathol 50: 266-268
`(1997) (“Sidorova”)
`
`Stromskaya et al., “Cell-specific effects of RAS oncogene and protein
`kinase C agonist TPA on P-glycoprotein function,” FEBS Letters, 368:
`373-376 (1995) (“Stromskaya”)
`
`Bechtereva et al., “DNA sequencing with thermostable Tet DNA
`polymerase from Thermus thermophilus,” Nucleic Acids Research, 17:
`10507 (1989) (“Bechtereva”)
`
`- 8 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`1122
`
`1123
`
`Description
`
`Asakura et al., “Cloning, Nucleotide Sequence, and Expression in
`Escherichia coli of DNA Polymerase Gene (polA) from Thermus
`thermophilus HB8,” Journal of Fermentation and Bioengineering,
`76(4): 265-269 (1993) (“Asakura”)
`
`Ikeda et al., “A Non-radioactive DNA Sequencing Method Using
`Biotinylated Dideoxynucleoside Triphosphates and ΔTth DNA
`Polymerase,” DNA Research, 2: 225-227 (1995) (“Ikeda”)
`
`Exhibit numbers 1124-1130 not used.
`
`1131
`
`Declaration of Dr. Floyd Romesberg, Ph.D.
`
`1132
`
`List of documents considered by Floyd Romesberg, Ph.D.
`
`1133
`
`1134
`
`1135
`
`1136
`
`Excerpt from Prosecution History of U.S. Patent No. 10,435,742
`(Declaration of Jingyue Ju and Accompanying Documents)
`
`Excerpt from Prosecution History of U.S. Patent No. 10,435,742
`(2019-02-15 Pre-interview First Office Action)
`
`Excerpt from Prosecution History of U.S. Patent No. 10,435,742
`(2019-02-26 Applicant Arguments/Remarks Made in an Amendment)
`
`Excerpt from Prosecution History of U.S. Patent No. 10,435,742
`(2019-05-13 Applicant Arguments/Remarks Made in an Amendment)
`
`1137 William R. Zimmerman Declaration in support of pro hac vice motion
`
`Exhibit numbers 1138-1145 not used.
`
`1146
`
`1147
`
`Stipulated Extension of Time #1, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 7, 19-cv-01681 (D. Del.) (Sept. 19, 2019)
`
`Stipulated Extension of Time #2, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 31, 19-cv-01681 (D. Del.) (Mar. 20, 2020)
`
`- 9 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`Description
`
`1148
`
`1149
`
`1150
`
`1151
`
`1152
`
`1153
`
`1154
`
`1155
`
`1156
`
`Stipulated Extension of Time #3, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 34, 19-cv-01681 (D. Del.) (Apr. 15, 2020)
`
`Stipulated Extension of Time #4, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 39, 19-cv-01681 (D. Del.) (May 20, 2020)
`
`Stipulated Extension of Time #5, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 45, 19-cv-01681 (D. Del.) (Jun. 25, 2020)
`
`Stipulated Extension of Time #6, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 50, 19-cv-01681 (D. Del.) (Jul. 14, 2020)
`
`Stipulated Extension of Time #7, The Trustees of Columbia University
`in the City of New York and Qiagen Sciences, LLC v. Illumina, Inc.,
`D.I. 65, 19-cv-01681 (D. Del.) (Oct. 2, 2020)
`
`Docket, The Trustees of Columbia University in the City of New York
`and Qiagen Sciences, LLC v. Illumina, Inc., 19-cv-01681 (D. Del.)
`(current as of Nov. 11, 2020)
`
`Scheduling Order, The Trustees of Columbia University in the City of
`New York and Qiagen Sciences, LLC v. Illumina, Inc., D.I. 17, 19-cv-
`01681 (D. Del.) (Dec. 11, 2019)
`
`Standing Order Regarding Criminal and Civil Jury Selections; Jury
`Trials; And Transition to Phase 2, In re: Court Operations Under the
`Exigent Circumstances Created by COVID-19 (D. Del.) (Sept. 1, 2020)
`
`Claim Construction Order, The Trustees of Columbia University in the
`City of New York and Qiagen Sciences, LLC v. Illumina, Inc., D.I. 60,
`19-cv-01681 (D. Del.) (Sept. 10, 2020)
`
`- 10 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`Description
`
`1157
`
`1158
`
`1159
`
`1160
`
`1161
`
`1162
`
`1163
`
`1164
`
`Joint Claim Construction Brief, The Trustees of Columbia University in
`the City of New York and Qiagen Sciences, LLC v. Illumina, Inc., D.I.
`54, 19-cv-01681 (D. Del.) (Aug. 10, 2020)
`
`Joint Claim Construction Appendix, The Trustees of Columbia
`University in the City of New York and Qiagen Sciences, LLC v.
`Illumina, Inc., D.I. 55, 19-cv-01681 (D. Del.) (Aug. 10, 2020)
`
`Columbia’s Motion for Reconsideration of the Court’s Claim
`Construction Order, The Trustees of Columbia University in the City of
`New York and Qiagen Sciences, LLC v. Illumina, Inc., D.I. 63, 19-cv-
`01681 (D. Del.) (Sept. 16, 2020)
`
`Illumina’s Answer to Columbia’s Motion for Reconsideration of the
`Court’s Claim Construction Order, The Trustees of Columbia
`University in the City of New York and Qiagen Sciences, LLC v.
`Illumina, Inc., D.I. 64, 19-cv-01681 (D. Del.) (Sept. 30, 2020)
`
`Transcript of Markman Hearing on Claim Construction, The Trustees
`of Columbia University in the City of New York and Qiagen Sciences,
`LLC v. Illumina, Inc., 19-cv-01681 (D. Del.) (Sept. 2, 2020)
`
`Columbia’s Claim Construction Presentation for Markman Hearing,
`The Trustees of Columbia University in the City of New York and
`Qiagen Sciences, LLC v. Illumina, Inc., 19-cv-01681 (D. Del.) (Sept. 2,
`2020)
`
`Illumina’s Claim Construction Presentation for Markman Hearing, The
`Trustees of Columbia University in the City of New York and Qiagen
`Sciences, LLC v. Illumina, Inc., 19-cv-01681 (D. Del.) (Sept. 2, 2020)
`
`Columbia’s Motion to Take Judicial Notice of Documents Filed in
`IPR2020-00988, The Trustees of Columbia University in the City of
`New York v. Illumina, Inc., D.I. 51, 19-2302 (Fed. Cir.) (Sept. 16,
`2020)
`
`- 11 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`Exhibit
`No.
`
`1165
`
`1166
`
`Description
`
`Illumina’s Opposition to Columbia’s Motion to Take Judicial Notice of
`Documents Filed in IPR2020-00988, The Trustees of Columbia
`University in the City of New York v. Illumina, Inc., D.I. 53, 19-2302
`(Fed. Cir.) (Sept. 25, 2020)
`
`Columbia’s Reply to Illumina’s Opposition to Columbia’s Motion to
`Take Judicial Notice of Documents Filed in IPR2020-00988, The
`Trustees of Columbia University in the City of New York v. Illumina,
`Inc., D.I. 54 19-2302 (Fed. Cir.) (Oct. 2, 2020)
`
`1167
`
`Exhibit number not used.
`
`1168
`
`Stipulation and Order amending the case schedule and cancelling the
`trial date, The Trustees of Columbia University in the City of New York
`and Qiagen Sciences, LLC v. Illumina, Inc., 19-cv-01681, D.I. 74
`(D. Del.) (Dec. 16, 2020)
`Exhibit submitted pursuant to emailed authorization of the PTAB on
`December 28, 2020.
`
`1169
`
`[Confidential] 2021 Settlement agreement [Filed July 20, 2021]
`
`1170
`
`[Confidential] 2017 Settlement agreement
`
`
`
`
`Dated: July 29, 2021
`
`
`
`
`
`Respectfully submitted,
`
`By: /Kerry Taylor/
`Kerry Taylor (Reg. No. 43,947)
`Nathanael R. Luman (Reg. No. 63,160)
`Michael L. Fuller (Reg. No. 36,516)
`William R. Zimmerman (pro hac vice)
`KNOBBE, MARTENS, OLSON & BEAR, LLP
`Attorneys for Petitioner
`ILLUMINA, INC.
`
`
`
`- 12 -
`
`
`
`Illumina v. Columbia
`IPR2020-01177– Patent 10,435,742
`
`CERTIFICATE OF SERVICE
`
`I hereby certify that true and correct copies of the foregoing ILLUMINA
`
`UPDATED EXHIBIT LIST and EXHIBIT 1170 are being served on July 29,
`
`2021, via email, pursuant to agreement of the parties, to counsel for the Trustees of
`
`Columbia University in the City of New York, at the email addresses below:
`
`John P. White
`jwhite@cooperdunham.com
`Gary J. Gershik
`ggershik@cooperdunham.com
`ColumbiaIPR@cooperdunham.com
`Cooper & Dunham, LLP
`30 Rockefeller Plaza, 20th Floor
`New York, NY 10112
`
`
`John D. Murnane
`VENABLE LLP
`jmurnane@venable.com
`1290 Avenue of the Americas
`New York, NY 10104
`
`Justin J. Oliver
`VENABLE LLP
`joliver@venable.com
`600 Massachusetts Ave.
`Washington, D.C. 20001
`
`
`
`Dated: July 29, 2021
`
`
`
`
`
`By: /Kerry Taylor/
`Kerry Taylor (Reg. No. 43,947)
`Nathanael R. Luman (Reg. No. 63,160)
`Michael L. Fuller (Reg. No. 36,516)
`William R. Zimmerman (pro hac vice)
`KNOBBE, MARTENS, OLSON & BEAR, LLP
`Attorneys for Petitioner
`ILLUMINA, INC.
`
`53869849
`
`
`
`