throbber
.L
`
`LU
`
`LJ‘I
`
`ON
`
`\1
`
`K0
`
`
`
`mattered?
`
`So it may make no difference at all;
`
`isn't that right?
`
`MR. DELAFIELD: Objection;
`
`Vague.
`
`Incomplete hypothetical, Calls for
`
`speculation.
`
`THE WITNESS: You know,
`
`if the
`
`purity was percent and that a percent was
`
`all one single peak,
`
`that would get a great
`
`deal of attention by all those groups you
`
`Said:
`
`the FDA,
`
`the reviewers, and including
`
`the comnany itself.
`
`BY MR. POLLACK:
`
`Q.
`
`All right“ But that's not the case
`
`for the Moriarty process?
`
`MR‘ DELAFIELD:
`
`Same objections.
`
`THE WITNESS:
`
`The Moriarty
`
`process doesn‘t fit your hypothetical
`
`example where you ask me to make up data.
`
`BY MR. POLLACK;
`
`Q,
`
`A.
`
`thhuh,
`
`The Moriarty process produces
`
`plus fold increase in impiritiee compared to
`
`'393 and that I‘m more comfortable with because
`
`that‘s real and not made up.
`
`Q.
`
`Oka”. Yeah, but I‘m just asking
`
`
`
`13-323
`
`UT Ex. 2058
`SteadyMed v. United Therapeutics
`iPR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1201 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1201 of 7335
`
`

`

`
`
`
`STEADYMED LTD. _, VS UNIT’TI) TH’QRAPWUTICS CORPORATION,
`Ruffolo,
`Robert on 08/19/20'6
`
`that weren’t real, you know, how Ear would your
`
`K
`opinion go?
`
`TIELD: Objection.
`
`U1
`
`0‘!
`
`in...\J
`
`)_J
`
`evaluation.
`
`THE WITNESS: Well,
`
`I mean, as
`
`said,
`
`i can't oEf th- t‘
`
`7 my head think
`
`of that.
`
`But
`
`in the example that you gave
`
`you required me to make up data,
`
`something scientists don't really
`
`at least not good scientists ‘~ we
`
`information like this .7 percent
`
`
`
`data, you know —— I have difficulty
`
`answering that question.
`
`And I gave you an example of
`
`made—up data thit you requested where it
`
`would make a big deal, a big difference but,
`
`I mean,
`
`I guess you can ask me to make up
`
`data all day long and I could come up with
`
`lots of silly examples where it would make a
`
`difference. And I’m happy to do that if you
`
`like.
`
`It's just not something i Go for a
`
`living.
`
`BY MR.
`
`PC’LLACK:
`
`
`Eli
`95
`
`sa Dreier Reporting Corp., n U.S. Legal Support Com'
`
`0 Third Avenue, New York, NY 10022
`(212) 557»
`P324
`UT'EX.2058
`
`SteadyMed v. United Therapeutics
`iPREOiBnOOOOG
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1202 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1202 of 7335
`
`

`

`U1
`
`0‘!
`
`)_J
`
`
`UNIT
`
`47D TH’QRAPWUTI CS
`STEADYMED LTD. _,
`Ruffolo,
`Robert on 08/19/2016
`
`VS
`
`CORPORATION,
`
`All ri
`
`gilt.
`
`Thank
`
`you.
`
`DEE
`
`questions.
`
`your time.
`
`Thanks so much for
`
`WITNESS:
`
`Thank you.
`
`Thank
`
`THE
`
`VIDEGGRAPHER:
`
`The time is
`
`:
`
`5:11 p.m. This
`
`concludes today's
`
`audiovisual depo
`
`sition of Dr. Robert R.
`
`Ruffolo. We‘re
`
`off the record.
`
`(
`
`f
`
`TH Hi
`
`f the stenographic record.)
`
`REPORTER: Mr. Delafield, do
`
`you wish a copy
`
`of the transcript?
`
`MT.
`
`could
`
`get it expedited.
`
`MR.
`
`REPORTER: What
`
`time frame?
`
`POLLACK: Three days.
`
`REPORTER:
`
`Do you wish a
`
`DELAFIELD:
`
`I want one.
`
`POI.:LAC I
`
`Elisa
`950
`
`Dr
`
`A 3.5. Legal Supper
`Third Avenue,
`New York, NY 100 2
`(212)
`
`UT‘Ex.2058
`
`Stead yMed v.
`
`Unwed Therapeufics
`iPR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1203 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1203 of 7335
`
`

`

`.4
`
`[\J
`
`U?
`
`0‘!
`
`)_J
`
`DELAFIELD: When can I get
`
`REPORTER; Three days.
`
`DELAFIELD:
`
`the quickest,
`
`nature having not been
`
`waived,
`
`the taking of the depogition
`
`
`STEADYMED LTD., VS UNITED THERAPEUTICS CORPORATION,
`Ruffolo,
`Robert on 08/19/2016
`
`Page 426
`
`get a rough,
`
`too.
`
`MR. DELAFIELD:
`
`If I could get
`
`expedited, both the rough and final.
`
`THE REPORTER: When do you want
`
`concluded at bzll p.m.)
`
`Elisa Dreier Reporting Corp., A U.Su Legal Support Company
`950 Third Avenue, New York, NY 10022
`(212)
`P326
`
`UT'EX.2058
`
`SteedyMed v. United Therapeutics
`iPREOiBnOOOOG
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1204 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1204 of 7335
`
`

`

`STEADYMED LTD. _, v 3 UNIT: ED THERAPE
`Ruffolo, Robert on 08/19/2016
`
`UTICS CORPORATION ,
`
`’0 LaLQ (T)
`
`Ll) [\J \l
`
`.4
`
`[\J
`
`U?
`
`0‘!
`
`)_J
`
`Change
`
`
`
`Change
`
`Change
`
`, A U.Su Legal Suppcrt Company
`Elisa Dreier Reporting Corp.
`950 Third Avenue,
`New York, NY 10-322
`(212) 5576558
`P327
`UT Ex. 2058
`SteadyMed v. United Therapeutics
`iPR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1205 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1205 of 7335
`
`

`

`.4
`
`[\J
`
`U?
`
`0‘!
`
`)_J
`
`
`STEADYMED LTD., VS UNITED THERAPEUTICS CORPORATION,
`Ruffolo,
`Robert on 08/19/2016
`
`DECLARATION UNDER PENALTY OF PERJURY
`
`I declare under penalty or
`
`perjury that I have read the entire transcript
`
`my Deposition taken in the captioned matter
`
`or the same has been read to me, and
`
`the same is true and accurate, save and
`
`except for changes and/or corrections,
`
`if
`
`any, as indicated by me on the DEPOSITION
`
`ERRATA SHEET hereof, with the understanding
`
`that I offer these change
`
`as if still under
`
`oath.
`
`Signed on the
`
`ROBERT R. RUFFOLO, JR., PHD
`
`Elisa Dreier Reporting Corp., A U.Su Legal Suppert Company
`950 Third Avenue, New York, NY 10022
`(212) 557»5558
`13-328
`UT Ex. 2058
`SteadyMed v. United Therapeutics
`iPR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1206 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1206 of 7335
`
`

`

`.\
`
`[\J
`
`U1
`
`0‘!
`
`)_J
`
`
`STEADYMED LTD. , VS UNITED THERAPEUTICS CORPORATION,
`Ruffolo, Robert on 08/19/2016
`
`Page
`
`Ll) [\J KD
`
`CERTIFICATE OF REPORTER
`
`DISTRICT OF COLL/IBIA
`
`I, DENISE: D. VICKERY,
`
`(ERR/EMF. and.
`
`Notary Public, hereby certify the witness was by
`
`me first duly sworn to testify to the trutl; that
`
`the foregoing deposition was taken at the time
`
`and place stated herein; and that the said
`
`deposition was recorded stenographically by me
`
`and thereafter reduced to printing under my
`
`direction;
`
`that said deposition is a true record
`
`of the testimony given by said witness.
`
`I certify the inspection,
`
`reading and
`
`signing of said deposition were NOT waived by
`
`counsel for the respective parties and by the
`
`witness; and that I am not a relative or employee
`
`of any of the 1arties, or a relative or employee
`
`of either c.unsel, and I am in no way interested
`
`My Cemmission expires February 14, 2018
`
`Denise D. Vickery, CRR/RMR
`
`A W.Si Legal Support Company
`L
`Elisa Dreier Reporting Corp.,
`5558
`950 Third Avenue, New York, NY 10-322
`(212) 557»
`
`UT'EX.2058
`
`SteadyiVied v. United Therapeutics
`iPREOiBnOOOOG
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1207 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1207 of 7335
`
`

`

`VS UNITED THERAPEUTICS CORPORATION,
`STEADYMED LTDq
`Robert on 08/19/2016
`Ruffolo,
`
`
`Exhibits
`
`1
`
`26624 267215
`281122
`104:3,23
`
`52:3
`
`1004 205:9
`
`
`
`23 311:1,21312:11,
`15,2025
`:11:36 107:17
`11:37 107:20
`
`g12 36:9 512211124
`112:3,12,18113:13,
`15114:11115:4,17,
`22125:5 203917,
`18 210212 212:17
`? 12:30 154:19
`12:34 154:24
`
`; 12:34 pm 155:1
`120 20319
`13 27010915
`110:18 205222
`206:5
`14151:18185;13
`236:4
`15 15025
`
`10 11351424
`151:21168'17,19
`1699101712024
`172:7
`17 12:2 22:3 62:18
`119:2712
`i 170 281:9
`1700 5:12
`
`j 175 252:5
`13 30:7
`
`
`
`Index:
`
`$500..3
`
`154:24182:3,14,17
`183:12,16,17,23
`184:20 186:4,25
`215:18 277:13
`20 352181205
`121:6,7168120
`190:1 272:13
`2006 7528,15 215216
`253120 3:08:17
`
`2007 1251612616,
`12,17128:3176:2
`177:23179:19
`19421725 233215,
`24 234:6
`2008 126:1245
`127212
`
`2009 74:20 75:11,12
`215:18 23324
`251 :23 274:20
`
`2012 126:12,17,21
`127:12128:5,8,25
`129:8130:18
`2013 296124
`2014 283:10,19
`2015 24:4
`2016 6:13 311:17
`2016—00006 6:9
`2023 26:21
`2035 197:17
`2047 241:17
`2043 242:2
`21 11241212
`123:21
`217 207212
`
`22 1212242512223
`123:4,17,22126:14,
`2125
`232 125:14
`
`24 5134
`26 32:58
`27 2:36:20
`28 57:16
`
`138:10,18,25
`
`:25141:8,17,24
`
`
`
`5
`
`EX 0001 Robert Ruff ! (a) 110:10
`010 081916 4:8 9:7:
`(0) 1125171023
`12
`1132011414
`EX 0002 Rohert Ruff :
`010 031916 4:10
`26:20:25
`EX 9003 Robert Ruff
`:010 031916 4:11
`5
`31:14 37:24 43:15
`51:3156:21236:7
`261:25
`EX 0004 Robert Ruff
`o1o 031010 4:14
`522715015
`EX 0005 Robert Ruff a
`010 001010 4:15
`1 7572023 95:13
`215151920
`25319 254:17
`
`(0) 031010920
`174:11
`
`(ti) 70:23 7102324
`72:15 73:2 974,15,
`21,24 9310,15
`99:6,231DD:18
`10102210210
`12212112310
`174:10
`
`0.1 81:22
`0.7% 263:1
`02 214:3,5
`05 231:17 318:5,13
`
`257:20
`g
`i EX 0000 Robert 000
`1015001010 4:13
`75:5 197:152023
`193:2 203:3,0 210:3
`g EX 0007 Rebert Ruff
`010 001010 4:21
`
`'
`
`g 205314
`1 EX 0008 Rasher: Rutt
`010 001010 5:3
`241:1522 242:14,
`15 243:7 255.14
`
`5
`
`j EX 0000 Robert Ruff
`010 001010 5:7
`' 242:1,57 250:25
`255:14 257:13
`
`g EX 0010 Robert Ruff
`ouo 001010 5:0
`. 25221283515
`1 2001729300
`EX 0011 Ruben Ruff
`11015031010 5:12
`1 3102023 311221
`312:11,15,20,25
`
`
`
`g 5:4 0712 33:3
`34:13 0219,22
`54:1225 5510,17
`50:1 1071712020
`1231912471301,
`8,18 140:4,25
`141:7,8,15,17,23,24
`1426831632
`164716923
`231:17,20,24
`271:11277L12
`317:20 318112
`323:7
`10 8:17,1930:7 92:0 g” 5213119124
`120:1,4
`114:3152:5190:7
`1002 205:25 20024
`272:8,11273:15
`f 1000 17522
`282:7,21 283:5,10,
`
`1 123 1552.9
`15,19 288:17 293:9
`230:21 232:1
`
`10,000 24825
`1040099 29721
`302:1
`
`139:1 140:2,13
` .
`1:25147:14
`$
`
`163:2018417
`0500 24:12
`19512151825
`196:1,2,5198:18
`
`g 31:14:17,113 37:24
`43:15 510155921
`195:2,1321524
`235:7 250:15
`
`
`g 2520,25 5514,15,
`25 68:18 76:2 96:12
`10721 15245
`
`Elisa Dreier Reporting Corp:, A Urs.
`950 Third Avanue, New York, NY 10022
`
`Legal Support Company
`557«5558
`(212)
`
`P330
`
`13.330
`
`UT‘EX.2058
`Steadyiv‘ted v. United Therapeutics
`1PR2016—00006
`UT EX.2058
`
`SteadyMed v. United Therapeutics
`1PR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1208 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1208 of 7335
`
`

`

`VS UNITED ‘I'I-IERAPEUTICS
`S'I‘EADYMED LTD. ,
`Ruffolo,
`Robert on 08/19/2016
`
`CORPO RAT I ON ,
`
`,
`
`251125317:9,15
`g
`j 3_ 15:20
`30 25:1,3152324
`25:3 35184315
`32 1561202418517,
`1018616 235:3
`237:7
`33 43:17
`
`1
`a
`
`i 34 4314,2025
`3142431523
`
`j 35 252:4
`35 238:2
`
`; 37 238:2
`
`38 1081722
`39:23 40:1
`
`.24 78:8 7924
`
`1051110819
`12422137322
`140131511011
`15315155210
`155122115718
`1588111215925
`172512151732,
`1817519 20820
`217:9,13 218310
`21924 2281419
`2332025 2341816,
`18 2352,14 23514
`2371215 258:17
`252:9 253:1 25514
`25925 270.89
`271:1 272515
`2811118 315217
`315.5911 317:2
`318:7 320:7,15
`32323
`
`j 3:13 250:15
`3114p.m 250:17
`1 3:21 2501720
`
`gg 52277122
`1242215815
`1832457824
`, 25020
`40 25121523 402
`185171584
`1
`1 400 15:20 24:23
`4:03 282:17
`
`
`
`4121 28211823
`
`5 75:6,72023 81:19
`8211,15 83:22
`8413,1524 85:4,
`1015,2025 8534,
`15 95:25 0513
`100:5 215151920
`219:2,5 2382
`
`24823 25319
`
`25417 257:20
`
`25:3 317:15
`
`0 15:15
`1 55 3210 35:25
`57 23520
`E 5111 325110
`5:11 pum 326113
`
`
`
`
`E 6 7516153124
`19721620231982
`203189 21018
`218124 22012
`253113,17,18,20
`25513 257120
`31 1 :17
`2512024 2612
`24:24 125:3
`26511521
`155 1251718
`6? 136191123
`162122163110
`16614182119
`59 4311316142217
`
`
`
`
`
`
`E 12712205514
`253:8 272:5 27521
`31611423 3171825
`318116 324113
`000 15:10
`13615 26212
`1822225
`80:25
`:25
`
`
`
`
`8
`
`8 24111622 242115
`24317 255114
`2881162122 29318
`296116 298116
`
`8,487,383 52:4
`8" 15:25
`85 19015
`81h 12525
`
`9
`
`9 69:6,7,11,14 70123
`71122 9714,16
`103125109219
`113119114112
`11828169124
`17112417213
`203125 2421157
`24917 250125
`255114 257113
`291225 2921715
`9's 164115
`18726 32317
`
`1'10 16125
`
`94 141216
`945 16416
`
`95 18311,1318421,7,
`22 18612518717
`26617
`950 6117
`
`9545 13716138219,
`514191624
`
`195123 267117
`’ 81123 3032
`
`30911023 31011
`15912218611921
`
`87:12 2672317
`28016 281:1,1523
`30312 30911023
`31021
`1601191613
`
`1601616111923
`641918013182211
`1871111921 18815.
`7,1818912019015,8
`266123 267114
`281122
`
`
`
`
`
`.
`
`185122
`263115
`
`05% 262110
`
`
`
`
`
`N 1841823
`15713
`15715 158117
`'111,12,1718214
`99.6 157116158211,
`16
`143162314417,
`
`2, 623145221
`1821214183115
`1841171861425
`194125 1951924
`19613 206219
`
`
`
`am. 611410711720
`abbreviated 270111
`abbreviations
`296111
`
`5131111); 192:15
`5108010118 13911520
`185216 201:1
`
`absoflutely 79:25
`8311 248:6 322112
`
`accept 188125153112
`19314 201 :20
`
`acceptabie 69:17,
`1922 71:15 72:3],
`10,12,25 731312219
`123:1 12419
`550555 90:23 91:2
`103:6
`ancordance 103125
`ACE 101912111
`achieved 236113
`
`
`
`acid 6913 7118,1012
`72:1821 74:8 79:17
`8014 81:8 97:20
`99:7 10113104125
`10611210914
`110114114118
`1181251221225
`j 4:03 [MT] 28218
`123111,12,1412418
`
`
`Elisa Dreier Reporting Corp., A U.S.
`950 Third AVEDHE, New York, NY 10022
`
`P831
`
`Legal Support Company
`(212) 557--5558
`UT‘EX.2058
`SteadyMed v. United Therapeutics
`iPR2016—00006
`UT EX.2058
`
`13.331
`
`SteadyMed v. United Therapeutics
`1PR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1209 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1209 of 7335
`
`

`

`STEADYMED LTD., VS UNITED THERAPEUTICS CORPORATION,
`Index:
`Ruffolo,
`Robert on 08/19/2016
`acknowledgement..applications
`
`1371213923
`140:16174:11,13
`273112
`
`acknewiedgement
`306:13
`
`‘
`
`; acting 28:25
`actions 153:10
`active 159:7,817815
`179:9 216:25
`activities 20:7
`
`i
`
`j activity 151,24
`1
`15:11 55:15 56:16
`259-12
`acts 255:1 299:1
`
`g actuai 157:2 183:10
`i acute 192:21
`add 30:4 32:7 53:16,
`‘ 21182:17294:14
`2951?) 296:4
`
`; added 30:3 33:18
`362171816
`
`1 adding 49142973
`i addition 57:1
`1
`1702017224
`19218 260:12
`296:22
`i additienai 30:16
`49:4 81:1 170:22
`
`; Additionally 262:6
`address 30920
`
`g addressed 40:1
`1 addressing 74:11
`administration
`211:1283:7 300:12
`advance 312:8
`
`; advancing 314:15
`
`advantages 238:8
`
`= averse
`3:2
`
`
`‘
`254.24 257:23
`258:7 259:5,0
`260:3,6,7,11,16,23
`261:15,17,21,22
`advertise 245:9
`
`j
`
`5 advice 17:14
`advisement 228:2
`aerobic 252:3
`
`5 affairs 132:17133z6,
`‘ 20134:25135:2,8
`283:9 302:17,18
`
`
`
`affect 77:3 201:6
`213.1024 239:9,23
`240:12 241:4
`255:15 285:4
`281:18
`affected 200119
`affects 239:15
`affirm 7:10
`affords 81:1
`AFTERNOON 156:1
`
`age 212:22
`agencies 244:9
`289:13
`
`agency 8:7152213
`153:25 204:13
`
`300:15,17301:7,14,
`25
`
`agent 116:2 213:21
`agents 251:14 253:6
`agree 44:22 52:22,
`23 53:17 55:3 59:14
`70:25 72:20 82:18
`132:8133:21
`1531615711
`1672518525
`18820195121028
`2122425 21422
`2212131318
`314:13 310:4
`
`agreed 46:7 256:22
`266.22 267:25
`306:1 314:6
`
`agreement 305:5
`agrees 281 :21
`air 244:7 245:21
`246:7
`airborne 243:23
`254:3
`
`aikyiating 116:2
`aiiergic 244:2 249:4,
`5 252:8 256:7,16,
`19,23 257:3,6
`aiiowabie 220:22
`
`aiiowed 3021,24
`42:3 43:6 95:9
`107:2 158:18
`170:23 180:6
`275:13 281:25
`294:13 295:17
`206:3
`
`aitering 237:2
`
`aiternate 19020
`
`f aiternative 53:4
`Aiternatively 51:17
`, ambiguity 205:22
`ambiguous 175:11
`amendment 268:14
`27711730911112,
`19,24 310:8,13,14
`f amendments
`308:23 309:8
`amine 28:25
`ammonia 109:21
`1101420119320
`121117
`
`1 amerphic 18:8
`amorphous 1813,10
`201:3
`amount 106:15
`1081819312 238:11
`
`; amounts 213:14
`anamg 60:13
`anaiyses 146:7
`153:18 200:10
`20815215:1218:2
`226:7 264:2
`
`analysis 43:9 62:16
`92251371121
`1452522 1462220
`147118148216
`149:16151'8152:9,
`25153i815415
`15715,15,16158:8,
`10159:10,12
`163019151417
`164224105112
`16613,1616716,9,13
`18014182218614
`189:11 190.25
`192125 1033:2122
`199:15 202119
`204113 208:6 215:7
`221112 226:5 234:5
`263:9 279:23
`281:10
`
`analyticai 16:18
`17:15 54:9,18
`5620,2225 5726,
`7 176:18
`
`analyze 292:15
`anaiyzed 164:2
`173:11
`
`
`
`anapnyiaxis 244:3
`animal 14:8,10,15,
`20
`animals 14:13 32:25
`34:11
`announced 131 :3
`announcement
`93:20
`announcements
`94:1,23
`annuai 226:9
`
`answering 74:21
`120:18 324:15
`answers 265:25
`antibiotics 59:21
`60:3,16 61:15
`243:13 247:20
`254:16
`
`anticipate 242:25
`antigens 249:23
`250:4 251:6 257:11,
`14,15
`anymore 30:10
`anytime 128:3,4
`AP 245.2
`APi 80:24 81 :3 82:3
`96:18 9721415736
`158:21 159:5,6
`160:18163:21
`181:2,9,11 198224
`216:7,9,15 217:14
`221:1 223:3 295:9
`
`apoiegize 32:6
`123:21 166:9
`
`Apneai 6:9 35:11
`appears 208:2
`appies 145:20
`148:21 165:19
`166:8,9,10167:10
`263:25 264:1
`
`appiicant 305:3
`appiicants 304:25
`305:21
`
`appiication 90:17
`125:1,5,13.15,16,
`17,24 198:13
`268:14 289:23
`290:1
`
`applications 125:25
`126:5 290:16
`
`
`
`
`
`Elisa Dr ier Reporting Corp., A UBS.
`950 Third Avenue, New York, NY 10022
`
`P332
`
`Legal Support Company
`(212) 557n5558
`UT‘EX.2058
`Steadyivied v. United Therapeutics
`iPR2016—00006
`UT Ex. 2058
`
`13.332
`
`SteadylVied v. United Therapeutics
`1PR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1210 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1210 of 7335
`
`

`

`VS UNITED THERAPEUTICS
`STEADYMED LTDq
`Robert on 08/19/2016
`Ruffolo,
`
`CORPORATION,
`Index:
`
`applies..
`
`
`base 1092011125
`113:20114:13,14
`based 14:1025
`32:23 34:9 37:12
`40:2 52:2,1523
`53-14 63:20 73:9
`82:5 87:5100:1
`10421 1361,25
`145:7153:22161:1,
`18166151742
`180:8185:17187:4
`188:3,24 201:12
`207:22 212:5
`25922 261:2
`265:21 266:21
`295:16 302:10
`320:20
`bases 119:13
`basic 66:24
`
`basicaiiy 11:23
`148,11 19:8 21:7
`2961625 243:18
`275:11
`
`basing 195:13
`basis 40:19 42:2
`58:18
`batch 1572615813
`159:11 1604510,
`172016136 180:2
`262:7
`batches 161:16
`162:2 281:6 306:7
`bathroern 250:11
`
`bedding 223:14
`Beecham 27:16
`28217
`begin 62:18
`beginning 23:4 26:7
`79:24 216:1277:11
`296:18
`
`begins 6:410721
`156:9 250:20
`
`
`
`appiies 38:15 74:7
`f appiy 1042412024
`173:9
`
`i
`
`:
`
`5
`
`‘
`
`approval 43:2 92:12
`151224152213
`1532919426 279222
`289212 298213
`30328 304216 30525
`306:8,9 307221
`approvals 189:19
`21124 287224
`
`approve 76:19
`152214211218
`29622
`
`; approved 22:5 41:6
`5
`4328 462711511213
`153225158218
`219216 267225
`277216 279217
`28021617 29723
`29924 300225 30127,
`15 305221 30622
`
`310218 315216
`1
`5 approving 277:22
`303:1
`
`f approximate 185:3
`187:6
`
`5
`
`; appreximately 6:14
`1
`2421716122316429
`5
`18322185217
`Aprii 24:2,4
`area 23:6 29:10
`50220 54223151219
`153.22 289219
`291:7 30225 303214
`30421218
`1
`j areas 131513314,
`2122 16222 54:22
`a arguing 20:18
`argument 17925
`305:14
`2
`i Argumentative
`231210 23329 30829
`
`f army 31:6
`art 38219512315
`I
`52220 54225103213
`104216105121
`
`5
`
`
`
`artistes 305:19
`
`aseptic 243:18
`aspect 19:6
`aspects 37:12
`assay 146:12,1320
`14919150315
`151:25 152:8
`153:23 154:1
`159:12160616723
`195:10,11196:10,
`20 197:2 199:2
`204:13 224:25
`310:8
`
`assays 146:16
`assess 13:25
`18824
`assessment 163:11
`192:25 241:9 264:3
`assessments 203:7
`assistance 134:2
`assistants 31:7
`
`assume 1721,13
`39:8 62:1190:2,14
`956,15 9621 190225
`211223 21221
`233211287:11,16
`313214
`assumed 88:14
`18520
`
`assuming 38:14
`16013 266:7
`
`iassumption 114:8:9
`182:1 233:12
`
`assumptiens 160:8
`assurance 222:23
`assure 2122:) 213:3
`21419 22323
`assured 281 :24
`Astrazeneca 12:25
`
`! attach 225:10,12
`attached 227:6
`attendance 9:15
`attention 289:7
`323:9
`
`attorney 36:14 38:6
`66:2467:12171:15
`292:5
`
`: atterneys 134:1
`313215
`attributabie 259:13
`
`audiovisuai 6:5
`325211
`
`August 6:13
`author 129:19
`298111
`autonomic 28:13
`1 Avenue 6:18
`
`average 161:17218
`1133:1319 164219
`1652517194225
`22121126227924
`26321 316224 32026
`321:9
`
`averages 138115
`26522
`avoided 300:13
`
`aware 37:2 602124
`6113 93214220,
`25143151512
`1592019619
`287:22 288.2425
`28922 2903612,
`1520 29420
`awareness 30021
`Aziiect 11214
`
`B
`
`bachelor's 51:19
`5325,12
`hack 15:4 31:4 66:2
`6821410722410823
`109291112111327,
`2311452214121
`1562131662613
`168111 17025
`171:20179211,13
`18526 208212
`215214 236.2
`247:16 257:18
`261224 282223
`283:2 29328 298116
`308216
`bacteria 61 :22
`249119202124
`252:3
`
`bacteria! 5312,13
`baiance 47:8 48:22
`50224 279225
`balanced 14:24
`
`baiances 44:3,13
`
`
`
`behalf 6:23 7136
`19:4 23:20
`belief 280:1
`believed 42:4
`254:21
`believes 192:5
`14321514427,14
`
`76:4
`arterial 193:11,19
`
`
`19422919
`1
`~z -:
`.
`70:14,
`i articie 205:9,18
`21271251218
`‘
`20623 24227
`2722222 273:1125
`
`
`Elisa Dr ier Reporting Corp., A UBS.
`950 Third Avenue, New York, NY 10022
`
`P333
`
`Legal Support Company
`(212) 557«5558
`UT‘EX.2058
`Steadyivied v. United Therapeutics
`iPR2016—00006
`UT Ex. 2058
`SteadylVied v. United Therapeutics
`1PR2016n00006
`
`6333
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1211 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1211 of 7335
`
`

`

`STEADYMED
`LTD., VS
`UNITED THERAPEUTICS CORPORATION,
`Ruffolo,
`
`9/2016Robert on 08/1 Index: bet ..Change
`
`281:3 293:1 295:16
`175:3177:25
`274:2,11 275:1,8,9,
`BSES 294.1622
`295:12 301122
`300:23 308:7 314:4
`14 278119 277:18
`180:11 182:9,23
`323:13
`184:11,25186:8
`278:21,23,25 279:7
`bet 322:21
`1873191425
`19413195520
`beta 20:5,10
`200:22 201:15
`betaniactam 241219
`204:17 206:9 208:9
`242215 254:16
`209:1525 211:8
`betauiactams 243:9
`214:8 215:9216:20
`244:4 245:14 247:5
`221:19 222218
`223:10 226:25
`229:6 233:9 234:2,
`20 239212 240:14
`249214 255:18
`285:8 286:18
`271:20 274:14
`275:24 288:8 281:4
`295:21 298:22
`317:13 320:10
`321:18 322:9 323:4
`324:4
`cancer 192:11
`
`cases 8:19,21,24,25
`9:1 13:417:23
`22:20 24:17 27:15,
`22 30:22 45:17,18
`47:2
`catch 250:10
`
`1 categories 259:7
`categery 219:11
`259:8 289:8
`
`caught 32:6
`; caution 35:22
`CEDR 211:2,17
`212:2.9,17
`ceii 253:10
`center 21022
`281 :22
`centered 267:8
`
`cephalosporin
`59:12
`
`; cephaiosporins
`243:10
`
`certainty 136:19
`certificate 137:20
`157:5,15158:10
`159:10 167:5
`186:14 202:18
`234:5
`certificates 148:16
`226:5 281:9
`
`chaiienging 20:15
`28724
`chance 36:1524627
`291:5
`
`
`
`budge 192:12
`huiiding 243:24
`244:11,12,14,15
`2452225 246:5
`buiidings 245:17,
`1920 246:3
`buiiet 76:4 79:10
`Bunce 283:8
`bunch 126:11
`
`caicuiate 137:9,14,
`25138:14183:13
`262:21 264:20
`caicuiated 13:63:24
`26218
`
`caicuiatien 136:10,
`23138:7,8,13,17
`13931525142212
`185:3 187:6,16
`caicuiatione 136:1,
`1513921114322
`183:22 187:25
`226:7
`caii 40:22172:12,13
`caiied 7:13 9:20
`182462213122
`1412:2224 15624
`1741519717
`219:16,21,22
`230:21 242:8
`255:15 2666,3914
`277:19 299:8
`293215 3:68:17
`
`
`
`big 278:5 306:11
`324:18
`
`binding 256:2
`bio 249:11 253:10
`
`biodrug 249:12
`bioicgic 247:10,13
`249:16 253:6
`
`bioiogicai 247:6
`251 :14
`biomoiecuie 211:12
`251:2
`bit 24:20 96:24
`171 :3 193:5 225:7
`289:5
`BLA 212:5
`
`bianking 282:3
`biocker 26:6
`biockers 20:11
`Board 6:9 35:11
`313:25 314:1,3
`Bob 129:5
`
`Bobby 7:2
`Boehringer 11:23
`Back 288:25 289:5,
`15 290:8
`borderiine 318218
`barn 28:19
`bottcm 32:9151;18
`20321 20523
`229:22 277:8,11
`branch 210:25
`brand 10:16
`branded 11:19
`break 154:14,15,21
`250:10,25 282:7
`breaks 259:6
`
`briefly 8:18198:6,11
`bring 26:16
`broad 15:3
`BS 176:24
`
`capahie 53:13
`capacities 135:6
`Capitai 177:4
`care 19221214
`213:10
`career 14251610
`44:3,13 243:9
`carried 73:3 82:2
`96:5,17 9721425
`carry 32:16 72:13
`77:20
`
`carryuthrough
`278:24
`
`carrying 72:15
`97:16 98:18 99:23
`
`carrycver 275:2
`carvediioi 18:24
`
`case11:816,12,15,
`22251271213: 5
`13 18:5,7,18 19
`
`45:5,15 48:22 5617
`62:3 77:25 87:15
`97:21 143:15
`146:18,23 159:22
`165:19177:21,22
`181:14 202:17
`214:6,11 255224
`
`change 26:8 39:10
`caiiing 173218
`4245,10 43:1,6,8
`45:7 74:15 76:11
`216:17 217:3,9
`Cails 62:25 63:14
`77:11,14,22,23
`66:14 91:17 94:8
`78:6,7,10,22,25
`80:3 92:14 93:5
`95:4,24 97:6 98:4,
`21 99910022
`107:6,14131:4
`101910215
`143241444318
`122:12128212
`17314 237:5
`131:7132213144:2
`239:22 246:10,16
`145:3146:4147:16
`24720 25113515
`15220 15320
`265:10 266:22
`157:21 158:15
`257:2 268:2,349,
`159:15,24161:9
`10,24 2695,1014,
`163:23 166:24
`19,20 270691618
`169:3,18171:1
`27325 2742122
`
`
`Elisa Dreier Reporting Corp., A U.S.
`950 Third Avenue, New York, NY 10022
`
`Legal Support Company
`(212}
`
`P334
`
`6334
`
`UT'EX.2058
`SteadyMed v. United Therapeutics
`1PR2016-00006
`UT Ex. 2055
`SteadylVied v. United Therapeutics
`1PR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1212 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1212 of 7335
`
`

`

`275:3 277:23,24,25
`279:10,19,21
`280:17 281:20
`300:7 303:3,24
`305:4,22 306:1,2
`309:23 310:1,6,7,
`1415 320:8
`changed 19:20
`42:21 ,24 43:4 52:7
`93:16,21237:14,18,
`24 260:17 261-321
`270:12
`
`changing 77:1,10
`236:13 237:2
`240:10 269:23
`309:9
`characteristic
`221:11322:13
`characteristics
`200:13
`characterization
`122:10 316:22
`characterize 164:19
`check 135201367
`137:18 208:12
`314:23
`
`checking 136:20
`chemicai 21:9,15
`71:6,21 83:25 94:17
`113:5114:16,17
`198:6,19 231:2,6
`315210 316:8
`chemist 49:18
`5013,16
`chemistry 14:2,3
`15:216:1,2,6,17,19
`49:20 50:15 51:16
`5246112153:
`15,
`19,2425 5
`8,
`4:4,
`9,
`1017.18 5
`6:20.22.
`63:19
`25 57:5,6,7,9
`142:23
`64:76 91:1
`1492715019
`176;16,17,18,19
`196:12 205:10
`
`chemistrye
`dominated 55:16
`
`chemistry." 51 :21
`chemists 1618,20
`17:14,15 4913,19,
`2152:9 57:3
`
`Chicago 76:8,13
`79:12 80:12 216.10,
`16 217:2 268:15
`269:1
`Children's 248:23
`choice 300:21
`Chokei 6:25
`chose 161:14
`
`chromatographic
`198:5 210118 220:8
`257223
`
`chromatography
`238:1014 239:3
`chronic 40:19 42:2
`192:21
`
`chronicaily 74:7
`128:18
`cite 255:8
`cited 307:23 309:19
`310:7
`
`citizen'e 2555:2912,
`16 286:1,7,24
`287:12,23 288:12.
`13 289:9 299:24
`304217
`claim 6219,22 64:6.
`12,25 65:10,14.16,
`17,25 66:1,4,11,12,
`19,20,2167:3,13,14
`68:1869:6,7,11,14
`70:23 71:22 72.21
`9741610325
`104:15109:16,18,
`19110z18111z24
`112:3,12.18113:13,
`15,19114:11,12
`115:4,17,22116:1,
`5192411721015
`118:6,8.14,24
`119:2,7,12,24
`120119201216,
`7,9,16,24,25122223
`1234161921
`124:6,7152:4,5
`153:1,3,6168:17,19
`1699102324
`170:17,19,20,23
`17112024 172:3,7
`235:22 273:1
`291:25 292227.15
`322:6
`
`
`
`claims 62:18 66:7,8
`152:14153:13
`169121702912
`272:25 291:10,18
`clarify 291:22
`clarifying 239:6
`cleaned 243216
`244:7,11
`cieaning 199:5,6
`clear 78:20 86:4
`120:17145:6
`210:21 218:1
`client 12:15
`clinical 14:17 21:3
`2210,18 29:12
`242:8 260:8 261:10
`315:12
`
`clinicaliy 315.17
`close 139181426
`162:8
`
`closely 51:16 52:21
`54:47 55:17
`clothes 246;10,16
`CMC 198:4,7199119
`209:18 213:1
`222:23 224:17
`
`225.0,7,10,12,20,22
`226:11,14,21
`243:15
`code 231:23
`
`Coie 12:201823
`coli 5916,17 61:22
`249:19 251:6,9
`252:4,22 257:11
`coile e 176:8,21
`
`5211811433
`151:18,21
`168:20 2196,1521
`220:3 4 7 8 221 :5 7
`16,25 222:13
`223:13 2213:4613
`2382,1014 2726,
`11 276:21
`comfortable 323:23
`comment 67:17
`87:13165220 203:2
`276:25
`commented 203:5
`
`commenting 74:12
`62:13110:19111:2
`
`
`
`commoniy 185:20
`186:12
`communications
`35:23 58:7
`
`companies 8:21
`13112213317
`245:3,8,11,15
`289:23
`
`8:7,10,22
`
` ,1
`7,2011215
`119:16 20: 52121
`
`29:1042:1744:5,15
`48:16 49:25 50:6
`60:1194:18158:12
`161:2,5 243:12
`274:11277:19
`28018 20 323:11
`
`
`166:11
`compare 14519
`148:21166111
`201:12 263124
`2912225 2926,11
`compared 148:12
`163:15165110
`170:10 263:25
`264129121017
`316211 323:22
`compares 166:17
`comparing 165:19
`camparism 87:19
`10121491161657
`167:2,11264:13
`2922?» 293:1
`
`comparisons 235:9
`; competent 15:20
`compilation 57:23
`1 compieted 70:23
`1 compieteiy 244:21
`245:19,23 246:5
`313:18 314117
`
`STEADYMED
`i'.1TD., VS UNITED THERAPEUTICS CORPORATION,
`Ruffolo,
`Robert on 08/19/2016
`Index: changed..completes
`claimed 62:22 64:7
`112:2131:16
`comments 104:20
`106:1,8,13108:7
`commercial 216:9,
`15,25
`common 83:25
`208:17 210:3 239:3
`256:20
`
`compietes 107:17
`154:24 250:15
`
`
`Elisa Dreier Reporting Corp., A 0.9,
`950 Third Avenue, New York, NY 10022
`
`Legal Support Company
`(212} SSVHSSSS
`UT Ex. 2058
`6-335
`Steadylvled v. United Therapeutics
`1PR2016—00006
`UT Ex. 2058
`
`13.335
`
`SteadyMed v. United Therapeutics
`lPR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1213 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1213 of 7335
`
`

`

`vs UNITED THERAPEUTICS
`STEADYMED LTD.,
`Ruffolo,
`Robert on 08/19/2016
`
`COR.ORATION,
`Index:
`complex..crystallcgraphy
`
`
`
`4,8 309:5 312:18
`corrected 32220
`correction 33:7,24
`3621,24
`corrections 27:6
`32:133:13 37:1
`
`correctiy 44:18
`80:20 81.412020
`121 :10 124:6
`1852321612
`286:3
`cost 4914,16
`counsel 6:19 7:18
`107:22156:11,18
`225:23 226:12
`227:4 250:6,22
`282:24
`count 63:10 252:4
`
`coupie 36:2 170:7
`214215 296:10
`302:2 305:15
`311:19
`courses 177:6
`court 6:16 7:9107:9
`covered 289:25
`covers 292116
`create 205:21
`0
`
`77:2 233:17
`244:15
`
`creating 134:2
`2031131121
`creation 311:24
`criteria 190:11
`cross
`contamination
`243:20
`crossover 246:7
`
`crudeiy 14:9 67:9.10
`crystal 13:10,15
`18:5,7,10,13,14
`201:2,10 202:2,3]
`crystaiiization
`173:7,13174216,
`15,19,23175:9,13,
`15,19177:8,22
`178:1,8,19 179:8
`201 :4 277:25
`
`crystallized 179:10
`crystaiiography
`18:11
`
`contention 20:5
`contents 37:22
`context 305:9
`continued 156:4,7
`contraindicated
`2012,20
`contraindication
`
`198:9,13
`0 275210
`.
`conversion 80:18
`178:3
`converted 122:8
`123:1
`convince 146:11
`convinced 146:15
`152:13
`
`convincing 224:23
`copy 325:15
`corner 205:23
`
`compiex 15:25 52:6
`191 :13
`
`Compiiance 283:1 O
`complicated 192:24
`component 59:14,
`16 226:6 240:5
`
`components 181:9
`226:10 256:20
`
`compound 40:14
`45:20 71:2325 72:2
`80:17 83:12 94:17
`98:24104:19,23
`105:25118:10,25
`120211121:11
`151:13168:23
`174:11 179:9 200:2.
`7,8,20 235:7,15,17,
`18,24 248:1 272:23
`273:15 274:7 307:7
`309:15 315:20
`
`compounded 169:5
`compounds 16:8
`62:2163:2,10,16
`64:11,19,25 65:59,
`131625 68:17 69:4
`1201222325
`174224 200:14
`212121 235:19
`238:6 271:13
`
`comprising 170:18,
`21 172:4
`
`concept 74:10
`170:17
`
`concern 10:2 60:3,
`5,10115:10116:12
`118:3 236:10
`249:18 251:5
`253:12 278:13,23
`300:11
`concerned 107:9
`111:9 255:10
`274:24 279:1
`30021517
`concerns 45:4
`48:23 50:25 75:1
`76:11 77:24
`concession 245:18
`conclude 99:21
`16327819 222:21
`concluded 326:13
`concludes 325:10
`
`conclusion 66:14
`87:14100:5171:1
`216:2,6 218:8 265:5
`conclusions 266:12
`confidence 183:1,
`131854187711,
`2018921264812,
`20 265:3
`confident 318:24
`confidentiai 88:7,
`15,18 89:9 95:72
`96:1
`
`27:3 200:14
`2 : 242:23
`276:15 284:9
`confused 123:14
`185:8 236:4 237:10
`confuses 236:19
`
`confusing 204:5
`congestive 20:1,3
`consideration
`130:10,14192:14
`considerations 47:9
`considered 43:11
`88:7 92:14 269:9
`278:10279:9,12,19
`309:12,24
`considers 303:8
`consistent 203:6
`
`consistentiy 280:2
`consisting 109:21
`consult 133:15
`consultant 8:5
`
`consulting 8:6,9
`consumes 92:24
`contact 23:17
`199:14
`contacted 24:8,9
`contaminant 245213
`2491253125919
`321:11
`contaminants
`251:19 25441019,
`20 255:5,10,15,20
`257:8 279:2 295:8
`321:12
`contaminate 243:23
`contamination
`59:11,12,13,14,20
`60:2 243:25 244:24
`
`Corp 6:17 286:2,6
`corporate 8:3 29:8
`Corporation 6:8
`283:8,16
`correct 2920,23
`33:23 37:25 41:7
`45:9 46:22 47:9
`5421520 59:19
`60:17 62:15 64:5
`69:1171:18 72:3,4,
`15,16 75:13 76:13,
`2425 77:4,12
`8011,14 81:15 83:8
`95212115231178
`119:12121:18
`134:7 136:13
`138:17140:20
`1462147561691
`180222 186:21
`189:1 202:24
`211:13 212:7
`216:14 219:20
`220:1228:10,11,14,
`1516 232:18
`246121 251:4,5,8,14
`253:24 255216
`256:11 263:24
`268:15 269:2,25
`270221 273:1
`274:12,17283:14
`284:24 297:2
`298:10,14,15 301:2,
`
`-n
`e unis
`950
`
`a Dreier Reporting Corp., A U.S: Legal Support Company
`New York, NY 10022
`557n5558
`(212)
`Third Avenue,
`UT‘EX.2058
`SieadyMed v: United Therapeutics
`iPR2015—00006
`UT'EX.2058
`
`P336
`
`13.336
`
`SteedyMcd v. United Therapeutics
`1PR2016n00006
`
`|PR2020-00770
`
`United Therapeutics EX2007
`Page 1214 of 7335
`
`IPR2020-00770
`United Therapeutics EX2007
`Page 1214 of 7335
`
`

`

`STEADYMED LTD., VS UNITED THERAPEUTICS CORPORATION,
`Ruffolo, Robert on 08/19/2016
`Index: current.,Delafie1d
`
`current 7:23 30.13
`‘ 1602241808
`curricuium 26:21
`curve 151:1915323
`cutoff 31824
`
`1 cv 27:4,5,7 305,11,
`1
`25 31:1
`Ecyeno 112:7114:13
`=
`118;11,13117:15
`
`1712517218
`173420174717
`175:2,1021 176:4,
`9,14177:10,24
`178:11,17179:2,14,
`21 18010231813,
`7,18182:8.22
`183:20184:4,10,24
`186:7187:2,13,23
`1889189323
`190:9191:3,24
`1931320194312,
`2119541919812,
`2319729198214
`1991223 200521
`201:14 202:4,14
`204:15 205:2 206:8,
`17,23 207:4,11,16
`208:1,8,15,22
`2091424 211514,
`2124 212:10
`213216214723
`215:8 216:19 217:4,
`17,22 218:13
`220:18221:8,18
`222:3,11,15,18
`223:5,920 224:7,14
`101:8,1824102:13,
`225:17 2262,1724
`25103218104:2,18
`227:7,12,16,21,23
`10562210617
`2281,22 2295,13
`10921 110:5,23
`2302,24 231:9
`111:10,13112:4,13,
`232:3,12 233:2,822
`25113:15115:5,18
`234:1,19 235:3,23
`116182011711121
`239:11,24 240:13
`119:8120:2,7,10
`122211 123:51242
`2415,13 2477,15
`248:4 249:13 250:1,
`12527126222
`6,9 251:16 252:15,
`127:13,15128:11
`18 2537,1025
`1292913031222
`13113132121339
`255:17,23 25625
`25725 258:4 259:1
`135222137:11
`260:19261:18
`13822013912
`264:14 265:7
`140:9141:1,4,10,19
`266:15 267:5 268:6,
`143251714419
`17 269716 270:1.
`145214031471,
`22 27171922
`15148:1,8149:2,12
`27217 273:3,16
`150:1,10,22151:14
`15211915310
`274:13 2752023
`27622 278:7 280:7
`15413182215720
`281:3,16 283:20
`158:14159:14,23
`285:4,18 286:9,11,
`100212221612821,
`25 2871425 289:1
`241522410321122
`290:2,104724
`164:12,15,21 165:7
`291:13,20 2929,18
`1661182316722
`2933517 29417
`169:2,14,17170:25
`
`
`dec 35:2
`E Decades 179g17
`December 125:5
`decide 140:1211z4
`decided 269:13,19
`decider 17:9
`decision 17:21
`21:24 35:10153z11
`193:4
`
`decisions 1757,12,
`15,18 50:18,21,23
`52:10 5321412913
`
`deciaratien 31:10,
`18,19,2325 32:4
`3419,2023 35:3
`37:6,17 43:15 51:3,
`7,13 64:14 87:25
`73:16 81:12 87:1,5
`100:8,13101:1,25
`102:15104:10,11
`105:17106:7,13
`1087109113 130:1
`134:3,6,8,16,20
`135:4,5138z16
`155:21 163:2
`172:1317322
`185:8197z25
`198:16 202:24
`225:11,13,16,18,21
`230:5,21 239:13
`242:12 281:24
`263:10 283:23
`285:6,20 286:15
`289:3 291:1293:18
`294:19 295:23
`298:9,24 301:23
`303:13 304:10
`312:3 314:11,12
`315213131922
`317:14
`decoration 247:19
`decreaee 49:16
`173:9 261:8
`decreases 46:21
`dedicated 244:16
`
`deepiy 17:10
`define 39:2 294:21
`296:11 307:9
`defined 121:14
`307:18
`
`definition 230:5,14
`276:8
`
`degree 51:15,19
`52:8,9 53:12
`Deiafieid 7:2 15:17
`24:8 25:13 34224
`35:1921 38:24
`3917,17 40:13 4129,
`17 42212
`
`01510303030003anth
`
`‘
`
`
`
`
`
`
`
`D
`
`77:19
`
`
`
`us 245:12
`g
`248215 249:3
`
`I 25120
`dEata 81:1910324
`'
`104:6135:21,25
`136:2 137318
`14322189210
`193:2 261:2 266221
`281:7 323118
`324:10,14,17,20
`E
`1 date 1252625 284:1,
`1 3,672
`1441140 21517
`
`E
`
`,
`
`283:10,18311:17
`dates 126:6,12
`127:3
`day 17:1,3 19:7 33:3
`34:14111:16
`24824 27425
`
`‘
`
`312:5,6 32420
`i
`1 days 305:1532521
`326:8
`5 DC 6:

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